KEGG   Homo sapiens (human): 1559Help
Entry
1559              CDS       T01001                                 

Gene name
CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
Definition
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)
Orthology
K17719  
cytochrome P450, family 2, subfamily C, polypeptide 9 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
Organism
hsa  Homo sapiens (human)
Pathway
Arachidonic acid metabolism
Linoleic acid metabolism
Retinol metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Metabolic pathways
Serotonergic synapse
Chemical carcinogenesis
Disease
H01205  
Coumarin resistance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Lipid metabolism
   00590 Arachidonic acid metabolism
    1559 (CYP2C9)
   00591 Linoleic acid metabolism
    1559 (CYP2C9)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    1559 (CYP2C9)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    1559 (CYP2C9)
   00982 Drug metabolism - cytochrome P450
    1559 (CYP2C9)
 Organismal Systems
  Nervous system
   04726 Serotonergic synapse
    1559 (CYP2C9)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    1559 (CYP2C9)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.48  (S)-limonene 6-monooxygenase
     1559 (CYP2C9)
    1.14.13.49  (S)-limonene 7-monooxygenase
     1559 (CYP2C9)
    1.14.13.80  (R)-limonene 6-monooxygenase
     1559 (CYP2C9)
    1.14.13.-  
     1559 (CYP2C9)
Cytochrome P450 [BR:hsa00199]
 Cytochrome P450, animal type
  CYP2 family
   1559 (CYP2C9)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
LinkDB All DBs
Structure
PDB: 

Jmol
Position
10q24
AA seq 490 aa AA seqDB search
MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKV
YGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKW
KEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICS
IIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFM
KSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTE
TTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYID
LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK
KSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVP
PFYQLCFIPV
NT seq 1473 nt NT seq  +upstreamnt  +downstreamnt
atggattctcttgtggtccttgtgctctgtctctcatgtttgcttctcctttcactctgg
agacagagctctgggagaggaaaactccctcctggccccactcctctcccagtgattgga
aatatcctacagataggtattaaggacatcagcaaatccttaaccaatctctcaaaggtc
tatggccctgtgttcactctgtattttggcctgaaacccatagtggtgctgcatggatat
gaagcagtgaaggaagccctgattgatcttggagaggagttttctggaagaggcattttc
ccactggctgaaagagctaacagaggatttggaattgttttcagcaatggaaagaaatgg
aaggagatccggcgtttctccctcatgacgctgcggaattttgggatggggaagaggagc
attgaggaccgtgttcaagaggaagcccgctgccttgtggaggagttgagaaaaaccaag
gcctcaccctgtgatcccactttcatcctgggctgtgctccctgcaatgtgatctgctcc
attattttccataaacgttttgattataaagatcagcaatttcttaacttaatggaaaag
ttgaatgaaaacatcaagattttgagcagcccctggatccagatctgcaataatttttct
cctatcattgattacttcccgggaactcacaacaaattacttaaaaacgttgcttttatg
aaaagttatattttggaaaaagtaaaagaacaccaagaatcaatggacatgaacaaccct
caggactttattgattgcttcctgatgaaaatggagaaggaaaagcacaaccaaccatct
gaatttactattgaaagcttggaaaacactgcagttgacttgtttggagctgggacagag
acgacaagcacaaccctgagatatgctctccttctcctgctgaagcacccagaggtcaca
gctaaagtccaggaagagattgaacgtgtgattggcagaaaccggagcccctgcatgcaa
gacaggagccacatgccctacacagatgctgtggtgcacgaggtccagagatacattgac
cttctccccaccagcctgccccatgcagtgacctgtgacattaaattcagaaactatctc
attcccaagggcacaaccatattaatttccctgacttctgtgctacatgacaacaaagaa
tttcccaacccagagatgtttgaccctcatcactttctggatgaaggtggcaattttaag
aaaagtaaatacttcatgcctttctcagcaggaaaacggatttgtgtgggagaagccctg
gccggcatggagctgtttttattcctgacctccattttacagaactttaacctgaaatct
ctggttgacccaaagaaccttgacaccactccagttgtcaatggatttgcctctgtgccg
cccttctaccagctgtgcttcattcctgtctga

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