KEGG   Homo sapiens (human): 2539Help
Entry
2539              CDS       T01001                                 

Gene name
G6PD, G6PD1
Definition
glucose-6-phosphate dehydrogenase (EC:1.1.1.49)
Orthology
K00036  
glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49]
Organism
hsa  Homo sapiens (human)
Pathway
Pentose phosphate pathway
Glutathione metabolism
Metabolic pathways
Carbon metabolism
Central carbon metabolism in cancer
Module
Pentose phosphate pathway (Pentose phosphate cycle)
Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
Disease
H00101  
Other phagocyte defects
H00668  
Anemia due to disorders of glutathione metabolism
H01375  
Glucose 6-phosphate dehydrogenase deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    2539 (G6PD)
  Carbohydrate metabolism
   00030 Pentose phosphate pathway
    2539 (G6PD)
  Metabolism of other amino acids
   00480 Glutathione metabolism
    2539 (G6PD)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    2539 (G6PD)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.49  glucose-6-phosphate dehydrogenase (NADP+)
     2539 (G6PD)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   2539 (G6PD)
  Exosomal proteins of colorectal cancer cells
   2539 (G6PD)
  Exosomal proteins of bladder cancer cells
   2539 (G6PD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
LinkDB All DBs
Structure
PDB: 

Jmol
Position
Xq28
AA seq 545 aa AA seqDB search
MGRRGSAPGNGRTLRGCERGGRRRRSADSVMAEQVALSRTQVCGILREELFQGDAFHQSD
THIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKA
TPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAV
TKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQN
LMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCL
VAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPR
GSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNEL
VIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQM
HFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWV
NPHKL
NT seq 1638 nt NT seq  +upstreamnt  +downstreamnt
atgggccggcggggctcagcccccggaaacggtcgtacacttcggggctgcgagcgcgga
gggcgacgacgacgaagcgcagacagcgtcatggcagagcaggtggccctgagccggacc
caggtgtgcgggatcctgcgggaagagcttttccagggcgatgccttccatcagtcggat
acacacatattcatcatcatgggtgcatcgggtgacctggccaagaagaagatctacccc
accatctggtggctgttccgggatggccttctgcccgaaaacaccttcatcgtgggctat
gcccgttcccgcctcacagtggctgacatccgcaaacagagtgagcccttcttcaaggcc
accccagaggagaagctcaagctggaggacttctttgcccgcaactcctatgtggctggc
cagtacgatgatgcagcctcctaccagcgcctcaacagccacatgaatgccctccacctg
gggtcacaggccaaccgcctcttctacctggccttgcccccgaccgtctacgaggccgtc
accaagaacattcacgagtcctgcatgagccagataggctggaaccgcatcatcgtggag
aagcccttcgggagggacctgcagagctctgaccggctgtccaaccacatctcctccctg
ttccgtgaggaccagatctaccgcatcgaccactacctgggcaaggagatggtgcagaac
ctcatggtgctgagatttgccaacaggatcttcggccccatctggaaccgggacaacatc
gcctgcgttatcctcaccttcaaggagccctttggcactgagggtcgcgggggctatttc
gatgaatttgggatcatccgggacgtgatgcagaaccacctactgcagatgctgtgtctg
gtggccatggagaagcccgcctccaccaactcagatgacgtccgtgatgagaaggtcaag
gtgttgaaatgcatctcagaggtgcaggccaacaatgtggtcctgggccagtacgtgggg
aaccccgatggagagggcgaggccaccaaagggtacctggacgaccccacggtgccccgc
gggtccaccaccgccacttttgcagccgtcgtcctctatgtggagaatgagaggtgggat
ggggtgcccttcatcctgcgctgcggcaaggccctgaacgagcgcaaggccgaggtgagg
ctgcagttccatgatgtggccggcgacatcttccaccagcagtgcaagcgcaacgagctg
gtgatccgcgtgcagcccaacgaggccgtgtacaccaagatgatgaccaagaagccgggc
atgttcttcaaccccgaggagtcggagctggacctgacctacggcaacagatacaagaac
gtgaagctccctgacgcctatgagcgcctcatcctggacgtcttctgcgggagccagatg
cacttcgtgcgcagcgacgagctccgtgaggcctggcgtattttcaccccactgctgcac
cagattgagctggagaagcccaagcccatcccctatatttatggcagccgaggccccacg
gaggcagacgagctgatgaagagagtgggtttccagtatgagggcacctacaagtgggtg
aacccccacaagctctga

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