KEGG   Homo sapiens (human): 2539Help
Entry
2539              CDS       T01001                                 

Gene name
G6PD, G6PD1
Definition
(RefSeq) glucose-6-phosphate dehydrogenase (EC:1.1.1.49)
  KO
K00036  
glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
Organism
hsa  Homo sapiens (human)
Pathway
Pentose phosphate pathway
Glutathione metabolism
Metabolic pathways
Carbon metabolism
Central carbon metabolism in cancer
Module
Pentose phosphate pathway (Pentose phosphate cycle)
Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
Disease
H00101  
Other phagocyte defects
H00668  
Anemia due to disorders of glutathione metabolism
H01375  
Glucose 6-phosphate dehydrogenase deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    2539 (G6PD)
  Carbohydrate metabolism
   00030 Pentose phosphate pathway
    2539 (G6PD)
  Metabolism of other amino acids
   00480 Glutathione metabolism
    2539 (G6PD)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    2539 (G6PD)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.49  glucose-6-phosphate dehydrogenase (NADP+)
     2539 (G6PD)
    1.1.1.363  glucose-6-phosphate dehydrogenase [NAD(P)+]
     2539 (G6PD)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   2539 (G6PD)
  Exosomal proteins of colorectal cancer cells
   2539 (G6PD)
  Exosomal proteins of bladder cancer cells
   2539 (G6PD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
LinkDB All DBs
Structure
PDB: 

Jmol
Position
Xq28
AA seq 515 aa AA seqDB search
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
NT seq 1548 nt NT seq  +upstreamnt  +downstreamnt
atggcagagcaggtggccctgagccggacccaggtgtgcgggatcctgcgggaagagctt
ttccagggcgatgccttccatcagtcggatacacacatattcatcatcatgggtgcatcg
ggtgacctggccaagaagaagatctaccccaccatctggtggctgttccgggatggcctt
ctgcccgaaaacaccttcatcgtgggctatgcccgttcccgcctcacagtggctgacatc
cgcaaacagagtgagcccttcttcaaggccaccccagaggagaagctcaagctggaggac
ttctttgcccgcaactcctatgtggctggccagtacgatgatgcagcctcctaccagcgc
ctcaacagccacatgaatgccctccacctggggtcacaggccaaccgcctcttctacctg
gccttgcccccgaccgtctacgaggccgtcaccaagaacattcacgagtcctgcatgagc
cagataggctggaaccgcatcatcgtggagaagcccttcgggagggacctgcagagctct
gaccggctgtccaaccacatctcctccctgttccgtgaggaccagatctaccgcatcgac
cactacctgggcaaggagatggtgcagaacctcatggtgctgagatttgccaacaggatc
ttcggccccatctggaaccgggacaacatcgcctgcgttatcctcaccttcaaggagccc
tttggcactgagggtcgcgggggctatttcgatgaatttgggatcatccgggacgtgatg
cagaaccacctactgcagatgctgtgtctggtggccatggagaagcccgcctccaccaac
tcagatgacgtccgtgatgagaaggtcaaggtgttgaaatgcatctcagaggtgcaggcc
aacaatgtggtcctgggccagtacgtggggaaccccgatggagagggcgaggccaccaaa
gggtacctggacgaccccacggtgccccgcgggtccaccaccgccacttttgcagccgtc
gtcctctatgtggagaatgagaggtgggatggggtgcccttcatcctgcgctgcggcaag
gccctgaacgagcgcaaggccgaggtgaggctgcagttccatgatgtggccggcgacatc
ttccaccagcagtgcaagcgcaacgagctggtgatccgcgtgcagcccaacgaggccgtg
tacaccaagatgatgaccaagaagccgggcatgttcttcaaccccgaggagtcggagctg
gacctgacctacggcaacagatacaagaacgtgaagctccctgacgcctatgagcgcctc
atcctggacgtcttctgcgggagccagatgcacttcgtgcgcagcgacgagctccgtgag
gcctggcgtattttcaccccactgctgcaccagattgagctggagaagcccaagcccatc
ccctatatttatggcagccgaggccccacggaggcagacgagctgatgaagagagtgggt
ttccagtatgagggcacctacaagtgggtgaacccccacaagctctga

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