| Entry |
|
|---|
| Gene name |
HPRT1, HGPRT, HPRT
|
|---|
| Definition |
hypoxanthine phosphoribosyltransferase 1 (EC:2.4.2.8)
|
|---|
| Orthology |
| hypoxanthine phosphoribosyltransferase [EC: 2.4.2.8] |
|
|---|
| Organism |
|
|---|
| Pathway |
| Purine metabolism | | Drug metabolism - other enzymes | | Metabolic pathways |
|
|---|
| Disease |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:hsa00001]
Metabolism
Nucleotide metabolism
00230 Purine metabolism
3251 (HPRT1)
Xenobiotics biodegradation and metabolism
00983 Drug metabolism - other enzymes
3251 (HPRT1)
Enzymes [BR:hsa01000]
2. Transferases
2.4 Glycosyltransferases
2.4.2 Pentosyltransferases
2.4.2.8 hypoxanthine phosphoribosyltransferase
3251 (HPRT1)
 |
|---|
| SSDB |
   |
|---|
| Motif |
 |
|---|
| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
|---|
| LinkDB |
 |
|---|
| Structure |
PDB: |
|---|
| Position |
Xq26.1
|
|---|
| AA seq |
218 aa  
MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA |
|---|
| NT seq |
657 nt  +upstreamnt +downstreamnt
atggcgacccgcagccctggcgtcgtgattagtgatgatgaaccaggttatgaccttgat
ttattttgcatacctaatcattatgctgaggatttggaaagggtgtttattcctcatgga
ctaattatggacaggactgaacgtcttgctcgagatgtgatgaaggagatgggaggccat
cacattgtagccctctgtgtgctcaaggggggctataaattctttgctgacctgctggat
tacatcaaagcactgaatagaaatagtgatagatccattcctatgactgtagattttatc
agactgaagagctattgtaatgaccagtcaacaggggacataaaagtaattggtggagat
gatctctcaactttaactggaaagaatgtcttgattgtggaagatataattgacactggc
aaaacaatgcagactttgctttccttggtcaggcagtataatccaaagatggtcaaggtc
gcaagcttgctggtgaaaaggaccccacgaagtgttggatataagccagactttgttgga
tttgaaattccagacaagtttgttgtaggatatgcccttgactataatgaatacttcagg
gatttgaatcatgtttgtgtcattagtgaaactggaaaagcaaaatacaaagcctaa |
|---|
