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<!-- Creation date: Jul 22, 2026 15:54:10 +0900 (GMT+9) -->
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        <subtype name="inhibition" value="--|"/>
        <subtype name="dephosphorylation" value="-p"/>
    </relation>
    <relation entry1="83" entry2="79" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="dephosphorylation" value="-p"/>
    </relation>
    <relation entry1="83" entry2="118" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="dephosphorylation" value="-p"/>
    </relation>
    <relation entry1="83" entry2="120" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="dephosphorylation" value="-p"/>
    </relation>
    <relation entry1="78" entry2="89" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="dephosphorylation" value="-p"/>
    </relation>
    <relation entry1="23" entry2="88" type="PPrel">
        <subtype name="inhibition" value="--|"/>
        <subtype name="dephosphorylation" value="-p"/>
    </relation>
    <relation entry1="123" entry2="119" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="124" entry2="119" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="292" entry2="137" type="GErel">
        <subtype name="expression" value="--&gt;"/>
    </relation>
    <relation entry1="104" entry2="98" type="PPrel">
        <subtype name="indirect effect" value="..&gt;"/>
    </relation>
    <relation entry1="35" entry2="33" type="PPrel">
        <subtype name="indirect effect" value="..&gt;"/>
    </relation>
    <relation entry1="34" entry2="33" type="PPrel">
        <subtype name="indirect effect" value="..&gt;"/>
    </relation>
    <relation entry1="55" entry2="20" type="PPrel">
        <subtype name="compound" value="28"/>
    </relation>
    <relation entry1="55" entry2="50" type="PPrel">
        <subtype name="compound" value="28"/>
    </relation>
    <relation entry1="19" entry2="104" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="26" entry2="47" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="25" entry2="44" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="25" entry2="46" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
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    <relation entry1="26" entry2="46" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
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        <subtype name="activation" value="--&gt;"/>
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        <subtype name="activation" value="--&gt;"/>
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    <relation entry1="35" entry2="34" type="PPrel">
        <subtype name="phosphorylation" value="+p"/>
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        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="97" entry2="88" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="108" entry2="275" type="PPrel">
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        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="275" entry2="103" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="indirect effect" value="..&gt;"/>
    </relation>
    <relation entry1="107" entry2="278" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="278" entry2="279" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
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        <subtype name="activation" value="--&gt;"/>
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    <relation entry1="279" entry2="100" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="indirect effect" value="..&gt;"/>
    </relation>
    <relation entry1="100" entry2="98" type="PPrel">
        <subtype name="binding/association" value="---"/>
    </relation>
    <relation entry1="274" entry2="54" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
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        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="284" entry2="39" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="284" entry2="38" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
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        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
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    <relation entry1="86" entry2="79" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
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    <relation entry1="85" entry2="80" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="85" entry2="79" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="49" entry2="133" type="PPrel">
    </relation>
    <relation entry1="287" entry2="36" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
</pathway>
