{
	"name":"aml03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"100483692 RNMT; LOW QUALITY PROTEIN: mRNA cap guanine-N7 methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"100483690 RNGTT; mRNA-capping enzyme\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]"
					},
					{
						"name":"100463640 CDK7; cyclin-dependent kinase 7 isoform X2\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"100464010 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]"
					},
					{
						"name":"100482851 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]"
					},
					{
						"name":"100484818 RAMAC; RNA guanine-N7 methyltransferase activating subunit\tK18708 FAM103A1; RNMT-activating mini protein"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"100472655 NCBP1; nuclear cap-binding protein subunit 1 isoform X1\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"100482239 NCBP2; nuclear cap-binding protein subunit 2 isoform X2\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					},
					{
						"name":"117797382 NCBP2L; nuclear cap-binding protein subunit 2-like\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"100466536 NUDT21; cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					},
					{
						"name":"100468772 CPSF7; cleavage and polyadenylation specificity factor subunit 7 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					},
					{
						"name":"100482011 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X2\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"100478336 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 isoform X2\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"100470130 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X2\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"100478082 CPSF1; cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"100464762 CPSF2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"100482521 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X2\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"100481121 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"100482615 CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform X1\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"100474965 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X4\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"100474664 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"100472927 WDR82; WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"100464499 PPP1CA; serine\/threonine-protein phosphatase PP1-alpha catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100471456 PPP1CB; serine\/threonine-protein phosphatase PP1-beta catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100476029 PPP1CC; serine\/threonine-protein phosphatase PP1-gamma catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100465474 RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"100472784 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"100473755 LOW QUALITY PROTEIN: RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"100469343 CSTF1; cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1"
					},
					{
						"name":"100465292 CSTF2; cleavage stimulation factor subunit 2 isoform X3\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"100474929 CSTF2T; cleavage stimulation factor subunit 2 tau variant\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"100480328 CSTF3; cleavage stimulation factor subunit 3 isoform X2\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"100474335 SYMPK; symplekin\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"100466329 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X2\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"100477663 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"100463815 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"100484971 small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"117796606 small nuclear ribonucleoprotein E-like\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"100469419 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"100471390 small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"100483824 SNRPG; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"109489114 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"109491022 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"117803042 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"100465179 LSM10; U7 snRNA-associated Sm-like protein LSm10 isoform X1\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10"
					},
					{
						"name":"100481900 LSM11; U7 snRNA-associated Sm-like protein LSm11\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11"
					},
					{
						"name":"100464762 CPSF2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"100482521 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X2\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"100465292 CSTF2; cleavage stimulation factor subunit 2 isoform X3\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"100474929 CSTF2T; cleavage stimulation factor subunit 2 tau variant\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"100474335 SYMPK; symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"100463845 SLBP; histone RNA hairpin-binding protein\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"100464752 oocyte-specific histone RNA stem-loop-binding protein 2-like\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"100467432 CASP8AP2; CASP8-associated protein 2\tK25593 CASP8AP2; CASP8-associated protein 2"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"100470725 SUPT4H1; transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"100463856 SUPT5H; transcription elongation factor SPT5 isoform X1\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"100464193 METTL3; N6-adenosine-methyltransferase catalytic subunit\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]"
					},
					{
						"name":"100484603 METTL14; N6-adenosine-methyltransferase non-catalytic subunit\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"100467181 METTL4; N(6)-adenine-specific methyltransferase METTL4\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]"
					},
					{
						"name":"100479575 METTL16; RNA N6-adenosine-methyltransferase METTL16 isoform X1\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"100477999 WTAP; pre-mRNA-splicing regulator WTAP isoform X1\tK22824 WTAP; pre-mRNA-splicing regulator WTAP"
					},
					{
						"name":"100478448 VIRMA; protein virilizer homolog isoform X1\tK22910 VIRMA; protein virilizer"
					},
					{
						"name":"100479873 RBM15; RNA-binding protein 15\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"100481170 RBM15B; putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"100482482 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X4\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"100471827 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X3\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"100463770 PAPOLG; poly(A) polymerase gamma isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"100481624 PAPOLA; poly(A) polymerase alpha isoform X3\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"105236373 PAPOLB; poly(A) polymerase beta\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"100470836 TENT2; poly(A) RNA polymerase GLD2 isoform X1\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]"
					},
					{
						"name":"100468113 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase\tK18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"100471907 BARD1; BRCA1-associated RING domain protein 1 isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"100463913 RBM26; RNA-binding protein 26 isoform X6\tK13192 RBM26; RNA-binding protein 26"
					},
					{
						"name":"100464623 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X2\tK19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"100472776 ALKBH5; RNA demethylase ALKBH5\tK10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"100466671 TARDBP; TAR DNA-binding protein 43\tK23600 TARDBP; TAR DNA-binding protein 43"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"100465010 DHX40; probable ATP-dependent RNA helicase DHX40\tK18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]"
				},
				{
					"name":"100475186 KIN; DNA\/RNA-binding protein KIN17 isoform X1\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"100464594 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 isoform X3\tK24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]"
				},
				{
					"name":"100470601 METTL22; methyltransferase-like protein 22 isoform X1\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]"
				},
				{
					"name":"100465558 TENT5B; terminal nucleotidyltransferase 5B\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"100476297 TENT5A; terminal nucleotidyltransferase 5A isoform X1\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"100478499 TENT5C; terminal nucleotidyltransferase 5C\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]"
				},
				{
					"name":"100466946 TENT5D; terminal nucleotidyltransferase 5D\tK23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]"
				},
				{
					"name":"100473115 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X3\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14"
				},
				{
					"name":"100482632 SRRT; serrate RNA effector molecule homolog isoform X1\tK27103 SRRT; serrate RNA effector molecule"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"100484705 RBM8A; RNA-binding protein 8A isoform X1\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"100465392 MAGOH; protein mago nashi homolog\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"100481045 protein mago nashi homolog 2\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"100470742 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"100466125 DDX39B; spliceosome RNA helicase DDX39B\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"100477327 EIF4A3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"100473447 CCDC174; coiled-coil domain-containing protein 174 isoform X1\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"100484375 CASC3; protein CASC3\tK14323 CASC3; protein CASC3"
					},
					{
						"name":"100477160 SAP18; histone deacetylase complex subunit SAP18 isoform X3\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"100478214 PNN; pinin\tK13114 PNN; pinin"
					},
					{
						"name":"100470890 ACIN1; apoptotic chromatin condensation inducer in the nucleus isoform X1\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus"
					},
					{
						"name":"100467265 RNPS1; RNA-binding protein with serine-rich domain 1 isoform X1\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"100479398 SRRM1; serine\/arginine repetitive matrix protein 1 isoform X3\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"100473279 THOC1; THO complex subunit 1 isoform X1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"100473142 THOC2; THO complex subunit 2 isoform X7\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"100481259 THOC3; THO complex subunit 3 isoform X2\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"100470742 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"100465138 THOC5; THO complex subunit 5 homolog isoform X1\tK13174 THOC5; THO complex subunit 5"
					},
					{
						"name":"100476687 THOC6; THO complex subunit 6 homolog isoform X1\tK13175 THOC6; THO complex subunit 6"
					},
					{
						"name":"100469998 THOC7; THO complex subunit 7 homolog\tK13176 THOC7; THO complex subunit 7"
					},
					{
						"name":"100464588 CHTOP; chromatin target of PRMT1 protein isoform X1\tK28424 CHTOP; chromatin target of PRMT1 protein"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"100471236 PCID2; PCI domain-containing protein 2 isoform X2\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"100465742 SEM1; 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"100470536 transcription and mRNA export factor ENY2-like\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"100484513 ENY2; transcription and mRNA export factor ENY2 isoform X1\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"100467705 CETN2; centrin-2 isoform X2\tK10840 CETN2; centrin-2"
					},
					{
						"name":"100464389 CETN3; centrin-3 isoform X2\tK16466 CETN3; centrin-3"
					},
					{
						"name":"100482346 MCM3AP; germinal-center associated nuclear protein isoform X1\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"100480868 TPR; nucleoprotein TPR isoform X5\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"100471008 RAE1; mRNA export factor\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"100467863 SEC13; protein SEC13 homolog isoform X2\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"100476542 NUP37; nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37"
					},
					{
						"name":"100467743 NUP85; nuclear pore complex protein Nup85 isoform X1\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"100466830 NUP43; nucleoporin Nup43\tK14305 NUP43; nuclear pore complex protein Nup43"
					},
					{
						"name":"100474401 NUP50; nuclear pore complex protein Nup50\tK14295 NUP50; nuclear pore complex protein Nup50"
					},
					{
						"name":"100470201 NUP54; nucleoporin p54\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"100468204 NUP62CL; nucleoporin-62 C-terminal-like protein\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"117794984 NUP62; nuclear pore glycoprotein p62\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"100465869 NUP88; nuclear pore complex protein Nup88 isoform X1\tK14318 NUP88; nuclear pore complex protein Nup88"
					},
					{
						"name":"100468546 NUP93; nuclear pore complex protein Nup93 isoform X2\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"100475098 NUP98; nuclear pore complex protein Nup98-Nup96 isoform X2\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"100479983 NUP107; nuclear pore complex protein Nup107 isoform X1\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"100473451 NUP133; nuclear pore complex protein Nup133\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"100472656 NUP188; nucleoporin NUP188 homolog\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"100478692 NUP153; nuclear pore complex protein Nup153 isoform X1\tK14296 NUP153; nuclear pore complex protein Nup153"
					},
					{
						"name":"100472557 NUP155; nuclear pore complex protein Nup155 isoform X1\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"100483792 NUP160; nuclear pore complex protein Nup160\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"100470301 NUP35; nucleoporin NUP35\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"100472705 NUP205; nuclear pore complex protein Nup205\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"100472022 NUP210L; nuclear pore membrane glycoprotein 210-like\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"100472432 NUP210; nuclear pore membrane glycoprotein 210 isoform X1\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"100466970 nuclear pore complex protein Nup214 isoform X4\tK14317 NUP214; nuclear pore complex protein Nup214"
					},
					{
						"name":"100466438 POM121L2; POM121-like protein 2\tK14316 POM121; nuclear pore complex protein Nup121"
					},
					{
						"name":"100469013 nuclear envelope pore membrane protein POM 121C\tK14316 POM121; nuclear pore complex protein Nup121"
					},
					{
						"name":"100467418 NUP58; nucleoporin p58\/p45 isoform X2\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"100478164 NUP42; nucleoporin NUP42 isoform X1\tK14321 NUPL2; nucleoporin-like protein 2"
					},
					{
						"name":"100465646 NDC1; nucleoporin NDC1\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"105239157 SEH1L; nucleoporin SEH1 isoform X1\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"100484820 LOW QUALITY PROTEIN: E3 SUMO-protein ligase RanBP2\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
					},
					{
						"name":"100476800 SENP2; sentrin-specific protease 2 isoform X1\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
					},
					{
						"name":"100468100 AAAS; aladin isoform X1\tK14320 AAAS; aladin"
					},
					{
						"name":"100464389 CETN3; centrin-3 isoform X2\tK16466 CETN3; centrin-3"
					},
					{
						"name":"100482913 GLE1; nucleoporin GLE1\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"100470225 LOW QUALITY PROTEIN: nuclear RNA export factor 2\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100481947 NXF1; nuclear RNA export factor 1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100484912 nuclear RNA export factor 2-like isoform X1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"105234339 LOW QUALITY PROTEIN: nuclear RNA export factor 3\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100467867 NXT1; NTF2-related export protein 1\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					},
					{
						"name":"100469359 NXT2; NTF2-related export protein 2 isoform X1\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"100468957 RAN; GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"117799753 GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"100477720 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D"
					},
					{
						"name":"100477450 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B"
					},
					{
						"name":"100466355 tumor necrosis factor ligand superfamily member 13 isoform X1\tK05475 TNFSF13; tumor necrosis factor ligand superfamily member 13"
					},
					{
						"name":"100468848 ELAVL1; ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"100470439 ELAVL4; ELAV-like protein 4 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"100472188 ELAVL3; ELAV-like protein 3 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"100472920 ELAVL2; ELAV-like protein 2 isoform X7\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"100482513 FAF2; FAS-associated factor 2 isoform X2\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"100470305 VCP; transitional endoplasmic reticulum ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"100470695 VCPKMT; protein-lysine methyltransferase METTL21D isoform X1\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]"
					},
					{
						"name":"100469427 TNPO2; transportin-2\tK18727 TNPO2; transportin-2"
					},
					{
						"name":"100466522 XPO1; exportin-1 isoform X1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"100474362 XPO7; exportin-7 isoform X2\tK18460 XPO7; exportin-7"
					},
					{
						"name":"100465006 RANBP17; ran-binding protein 17\tK24115 RANBP17; Ran-binding protein 17"
					},
					{
						"name":"100469193 RANGAP1; ran GTPase-activating protein 1 isoform X2\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"100466750 TAF15; TATA-binding protein-associated factor 2N isoform X1\tK14651 TAF15; transcription initiation factor TFIID subunit 15"
					},
					{
						"name":"100467826 NUTF2; nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"100463829 EIF4E1B; eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100465592 EIF4E; eukaryotic translation initiation factor 4E isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100483338 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100466854 EIF4A1; eukaryotic initiation factor 4A-I\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"100481978 EIF4A2; eukaryotic initiation factor 4A-II isoform X2\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"100465360 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X6\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100470670 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100478604 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100466347 EIF4B; eukaryotic translation initiation factor 4B isoform X4\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"100474290 EIF4H; eukaryotic translation initiation factor 4H\tK24086 EIF4H; translation initiation factor 4H"
					},
					{
						"name":"100469745 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1"
					},
					{
						"name":"100473926 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2"
					},
					{
						"name":"105235994 EIF4EBP3; eukaryotic translation initiation factor 4E-binding protein 3\tK18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3"
					},
					{
						"name":"100477199 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"100478569 ANGEL2; protein angel homolog 2 isoform X1\tK18729 ANGEL; protein angel"
					},
					{
						"name":"100482481 ANGEL1; protein angel homolog 1\tK18729 ANGEL; protein angel"
					},
					{
						"name":"100467605 FXR2; fragile X mental retardation syndrome-related protein 2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100471726 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100472255 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100467958 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"100475933 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"100472921 GEMIN5; gem-associated protein 5 isoform X2\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"100464097 TACC3; transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"100463552 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100481594 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X5\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100482740 cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100484423 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100464548 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"100464649 GIGYF2; GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"100484297 GIGYF1; GRB10-interacting GYF protein 1 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"100465799 PABPC4; LOW QUALITY PROTEIN: polyadenylate-binding protein 4\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100466038 LOW QUALITY PROTEIN: polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100475370 polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100480222 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100482395 PABPC5; polyadenylate-binding protein 5\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100482751 PABPC4L; polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100483251 PABPC1L; polyadenylate-binding protein 1-like isoform X2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100474807 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1"
					},
					{
						"name":"100465975 PAIP2B; polyadenylate-binding protein-interacting protein 2B isoform X2\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"100475115 PAIP2; polyadenylate-binding protein-interacting protein 2\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"100475276 SKIV2L; helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"100477361 DEAF1; deformed epidermal autoregulatory factor 1 homolog\tK23041 DEAF1; deformed epidermal autoregulatory factor 1"
					},
					{
						"name":"100475568 MCTS1; malignant T-cell-amplified sequence 1\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"100483510 malignant T-cell-amplified sequence 1\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"100469905 DENR; density-regulated protein\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex",
					"children":[
					{
						"name":"100473834 APOBEC1; C->U-editing enzyme APOBEC-1\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"100468305 A1CF; APOBEC1 complementation factor\tK24978 A1CF; APOBEC1 complementation factor"
					}
					]
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"100483993 PYM1; partner of Y14 and mago isoform X2\tK14294 WIBG; partner of Y14 and mago"
					},
					{
						"name":"100467781 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100467816 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100469027 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100475689 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100475735 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X2\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"117798384 heterogeneous nuclear ribonucleoprotein A3-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100465519 DAZAP1; DAZ-associated protein 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"100479973 MSI2; RNA-binding protein Musashi homolog 2\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"100480137 MSI1; RNA-binding protein Musashi homolog 1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"100471584 HBS1L; HBS1-like protein isoform X1\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"100475235 PELO; protein pelota homolog\tK06965 PELO; protein pelota"
					},
					{
						"name":"100479030 PABPN1L; LOW QUALITY PROTEIN: embryonic polyadenylate-binding protein 2\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"100481351 LOW QUALITY PROTEIN: ATP-dependent RNA helicase DDX19A\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"105234868 LOW QUALITY PROTEIN: ATP-dependent RNA helicase DDX19B-like\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"100472450 DDX25; ATP-dependent RNA helicase DDX25 isoform X2\tK18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]"
					},
					{
						"name":"100465848 XAB2; pre-mRNA-splicing factor SYF1\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"100477185 SARNP; SAP domain-containing ribonucleoprotein isoform X1\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"100480725 RCC1; regulator of chromosome condensation isoform X1\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"100478993 LARP6; la-related protein 6 isoform X1\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"100467966 PURA; transcriptional activator protein Pur-alpha\tK21772 PURA; transcriptional activator protein Pur-alpha"
					},
					{
						"name":"105239655 PURB; LOW QUALITY PROTEIN: transcriptional activator protein Pur-beta\tK21799 PURB; transcriptional activator protein Pur-beta"
					},
					{
						"name":"100473211 POLDIP3; polymerase delta-interacting protein 3\tK22414 POLDIP3; polymerase delta-interacting protein 3"
					},
					{
						"name":"100463562 zinc finger CCCH domain-containing protein 11A isoform X2\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"100464875 LENG8; leukocyte receptor cluster member 8 isoform X1\tK23802 LENG8; SAC3 family protein LENG8\/THP3"
					},
					{
						"name":"100466962 PATL2; protein PAT1 homolog 2\tK24823 PATL2; protein PAT1 homolog 2"
					},
					{
						"name":"100479816 FYTTD1; UAP56-interacting factor\tK28772 FYTTD1; UAP56-interacting factor"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"100483442 ETF1; eukaryotic peptide chain release factor subunit 1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"100465019 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"100472226 GSPT2; eukaryotic peptide chain release factor GTP-binding subunit ERF3B\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"100480150 UPF1; LOW QUALITY PROTEIN: regulator of nonsense transcripts 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"100482868 UPF2; regulator of nonsense transcripts 2 isoform X2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"100478254 UPF3A; regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"100479178 UPF3B; regulator of nonsense transcripts 3B isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"100464293 PPP2CA; serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform X1\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100473021 PPP2CB; serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100482129 PPP2R1A; serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"100482604 PPP2R1B; serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"100469264 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"100478681 PPP2R2B; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X7\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"100480910 PPP2R2A; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X10\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"100481821 PPP2R2D; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"100465950 PPP2R3B; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"100466255 PPP2R3C; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X2\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"100478108 PPP2R3A; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X3\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"100463538 PPP2R5D; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"100466685 PPP2R5C; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"100471672 PPP2R5B; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"100472488 PPP2R5E; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"100480070 PPP2R5A; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"100477904 SMG1; serine\/threonine-protein kinase SMG1 isoform X3\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"100470386 SMG5; protein SMG5 isoform X1\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"100480996 SMG6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"100476578 SMG7; protein SMG7 isoform X2\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"100466348 SMG8; protein SMG8\tK18734 SMG8; protein SMG8"
					},
					{
						"name":"100468609 SMG9; protein SMG9 isoform X3\tK18735 SMG9; protein SMG9"
					},
					{
						"name":"100464649 GIGYF2; GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"100484297 GIGYF1; GRB10-interacting GYF protein 1 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"100470097 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"100478315 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform X1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"100469863 DHX34; probable ATP-dependent RNA helicase DHX34 isoform X1\tK20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]"
					},
					{
						"name":"100474610 GTPBP1; GTP-binding protein 1 isoform X1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"100471761 PUM3; pumilio homolog 3 isoform X2\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"100467505 MYO5C; unconventional myosin-Vc isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"100467758 MYO5A; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"100476593 MYO5B; unconventional myosin-Vb\tK10357 MYO5; myosin V"
					},
					{
						"name":"100472389 BICD2; protein bicaudal D homolog 2 isoform X1\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"100474952 BICD1; protein bicaudal D homolog 1 isoform X1\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"100472483 EXD1; piRNA biogenesis protein EXD1 isoform X1\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals",
					"children":[
					{
						"name":"100466132 ACTG1; actin, cytoplasmic 2\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117800125 actin, cytoplasmic 1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117800181 actin, cytoplasmic type 5 isoform X1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117800361 actin, cytoplasmic 1-like\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117800408 actin, cytoplasmic 1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"100471292 MBP; myelin basic protein isoform X1\tK17269 MBP; myelin basic protein"
					},
					{
						"name":"100464155 VIM; vimentin\tK07606 VIM; vimentin"
					},
					{
						"name":"100467789 metallothionein-1-like\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"100468044 metallothionein-1A\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"100468297 metallothionein-1-like\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"105236726 metallothionein-2E-like\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"100464396 MYC; myc proto-oncogene protein\tK04377 MYC; Myc proto-oncogene protein"
					},
					{
						"name":"100478281 embryonic growth\/differentiation factor 1\tK05495 GDF1; growth differentiation factor 1"
					},
					{
						"name":"100478611 TBX6; T-box transcription factor TBX6\tK10180 TBX6; T-box protein 6"
					}
					]
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"100475455 ZBP1; Z-DNA-binding protein 1 isoform X2\tK12965 ZBP1; Z-DNA binding protein 1"
					},
					{
						"name":"100465976 FUBP3; far upstream element-binding protein 3 isoform X1\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"100474332 KHSRP; far upstream element-binding protein 2\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"100475812 FUBP1; far upstream element-binding protein 1 isoform X6\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"100469825 EEF1A1; LOW QUALITY PROTEIN: elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"100470920 elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"100471885 elongation factor 1-alpha 2\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"100476280 elongation factor 1-alpha, somatic form\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"109489905 elongation factor 1-alpha 1-like\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"117800367 elongation factor 1-alpha, somatic form-like\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"117802686 elongation factor 1-alpha 1-like\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"117804139 elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"100463848 EEF1G; elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"117800293 elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"100470912 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2\/B1 isoform X1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1"
					},
					{
						"name":"100481604 HAX1; HCLS1-associated protein X-1 isoform X1\tK16220 HAX1; HCLS1-associated protein X-1"
					},
					{
						"name":"100478408 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1"
					},
					{
						"name":"100466791 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X7\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"100470208 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X2\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"100478844 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 isoform X1\tK13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3"
					},
					{
						"name":"100482947 PTBP1; polypyrimidine tract-binding protein 1\tK13218 PTBP1; polypyrimidine tract-binding protein 1"
					},
					{
						"name":"100463552 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100481594 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X5\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100482740 cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100484423 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"100467605 FXR2; fragile X mental retardation syndrome-related protein 2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100471726 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100472255 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100467958 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"100475933 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"100469688 PCBP2; poly(rC)-binding protein 2\tK13162 PCBP2; poly(rC)-binding protein 2"
					},
					{
						"name":"100473695 PCBP4; poly(rC)-binding protein 4 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"100483595 PCBP3; poly(rC)-binding protein 3 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"100474973 CAPRIN1; caprin-1 isoform X1\tK18743 CAPRIN1; caprin-1"
					},
					{
						"name":"100477455 CAPRIN2; caprin-2 isoform X1\tK18744 CAPRIN2; caprin-2"
					},
					{
						"name":"100470605 LOW QUALITY PROTEIN: Y-box-binding protein 1-like\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"100472801 YBX1; Y-box-binding protein 1\tK09276 YBX1; Y-box-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"100464646 XRN1; 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"100464244 AGO2; protein argonaute-2 isoform X2\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"100465651 AGO3; protein argonaute-3 isoform X6\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"100465900 AGO4; protein argonaute-4 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"100482671 AGO1; protein argonaute-1 isoform X2\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"100463829 EIF4E1B; eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100465592 EIF4E; eukaryotic translation initiation factor 4E isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100483338 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100480150 UPF1; LOW QUALITY PROTEIN: regulator of nonsense transcripts 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"100464548 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"100477267 DDX6; probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"100467313 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"100469502 MEX3B; RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"109490790 MEX3A; RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"100482824 FASTK; fas-activated serine\/threonine kinase isoform X3\tK08290 FASTK; Fas-activated serine\/threonine kinase [EC:2.7.11.8]"
					},
					{
						"name":"100473185 LSM14B; protein LSM14 homolog B isoform X1\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"100473202 LSM14A; protein LSM14 homolog A isoform X2\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"100484740 PCBP1; poly(rC)-binding protein 1\tK12889 PCBP1; poly(rC)-binding protein 1"
					},
					{
						"name":"100469688 PCBP2; poly(rC)-binding protein 2\tK13162 PCBP2; poly(rC)-binding protein 2"
					},
					{
						"name":"100470605 LOW QUALITY PROTEIN: Y-box-binding protein 1-like\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"100472801 YBX1; Y-box-binding protein 1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"100470132 AJUBA; LIM domain-containing protein ajuba isoform X1\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"100474733 WTIP; Wilms tumor protein 1-interacting protein isoform X1\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"100483063 LIMD1; LIM domain-containing protein 1\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"100473834 APOBEC1; C->U-editing enzyme APOBEC-1\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"100464783 LOW QUALITY PROTEIN: DNA dC->dU-editing enzyme APOBEC-3H\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"100483325 DNA dC->dU-editing enzyme APOBEC-3G isoform X1\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"100483573 DNA dC->dU-editing enzyme APOBEC3 isoform X1\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"100481166 MOV10; helicase MOV-10 isoform X4\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"100477779 PNRC2; proline-rich nuclear receptor coactivator 2\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2"
					},
					{
						"name":"100483263 TNPO1; transportin-1 isoform X2\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"100477904 SMG1; serine\/threonine-protein kinase SMG1 isoform X3\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"100470386 SMG5; protein SMG5 isoform X1\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"100480996 SMG6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"100476578 SMG7; protein SMG7 isoform X2\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"100464527 ZFP36; mRNA decay activator protein ZFP36\tK15308 TTP; tristetraprolin"
					},
					{
						"name":"100468989 ZFP36L1; mRNA decay activator protein ZFP36L1 isoform X1\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"100475030 ZFP36L2; mRNA decay activator protein ZFP36L2\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"100463935 LOW QUALITY PROTEIN: protein lin-28 homolog A-like\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"100474879 LIN28B; protein lin-28 homolog B\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"100484733 LIN28A; LOW QUALITY PROTEIN: protein lin-28 homolog A\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"100466808 HTT; huntingtin\tK04533 HD; huntingtin"
					},
					{
						"name":"100476200 importin-8\tK18755 IPO8; importin-8"
					},
					{
						"name":"100466363 BICC1; protein bicaudal C homolog 1 isoform X1\tK18756 BICC1; protein bicaudal C"
					},
					{
						"name":"100467781 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100467816 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100469027 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100475689 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100475735 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X2\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"117798384 heterogeneous nuclear ribonucleoprotein A3-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"100469628 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"100465508 LARP1B; la-related protein 1B isoform X4\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"100470425 LARP1; la-related protein 1 isoform X1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"100473144 ATXN2L; ataxin-2-like protein isoform X1\tK23625 ATXN2; ataxin-2"
					},
					{
						"name":"100475037 ATXN2; ataxin-2 isoform X1\tK23625 ATXN2; ataxin-2"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"100473528 DCP2; m7GpppN-mRNA hydrolase isoform X1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"100481669 DCP1A; mRNA-decapping enzyme 1A isoform X1\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"100479967 DCP1B; mRNA-decapping enzyme 1B isoform X1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"100470506 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"100483807 LSM2; U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"100473950 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"100477624 LSM4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"100472616 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"100477883 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"100465685 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"100479478 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"100464655 KLC1; kinesin light chain 1 isoform X3\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"100481191 KLC3; kinesin light chain 3\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"100483172 KLC2; kinesin light chain 2\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"100484737 KLC4; kinesin light chain 4\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"100467505 MYO5C; unconventional myosin-Vc isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"100467758 MYO5A; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"100476593 MYO5B; unconventional myosin-Vb\tK10357 MYO5; myosin V"
					},
					{
						"name":"100463766 TUBA8; tubulin alpha-8 chain isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100464995 TUBAL3; tubulin alpha chain-like 3 isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100466505 tubulin alpha-4A chain isoform X2\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100468269 TUBA4B; LOW QUALITY PROTEIN: putative tubulin-like protein alpha-4B\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100470688 LOW QUALITY PROTEIN: tubulin alpha-3 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100475162 LOW QUALITY PROTEIN: tubulin alpha-1C chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100480515 tubulin alpha-8 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100463552 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100481594 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X5\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100482740 cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100484423 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100472921 GEMIN5; gem-associated protein 5 isoform X2\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"100464097 TACC3; transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"100475056 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"100477033 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"100481885 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"100474169 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X4\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"100483517 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"100464278 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"100473214 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X3\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"100474935 CNOT6L; CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"100478261 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"100473287 CNOT7; CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"100474446 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"100472950 GARRE1; uncharacterized protein KIAA0355 homolog\tK26671 GARRE1; granule associated Rac and RHOG effector protein 1"
					},
					{
						"name":"100465652 DIS3L2; DIS3-like exonuclease 2\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"100471669 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X7\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"100483709 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"100467646 BTG3; protein BTG3\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100482458 TOB2; protein Tob2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100482779 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100483106 BTG4; protein BTG4\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100484707 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100484798 TOB1; protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100477199 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"100483301 PATL1; protein PAT1 homolog 1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"100473281 EDC3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"100468074 EDC4; enhancer of mRNA-decapping protein 4 isoform X2\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"100473576 NANOS2; nanos homolog 2\tK18760 NANOS2; protein nanos 2"
					},
					{
						"name":"100474716 NANOS3; nanos homolog 3\tK18761 NANOS3; protein nanos 3"
					},
					{
						"name":"100482868 UPF2; regulator of nonsense transcripts 2 isoform X2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"100478254 UPF3A; regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"100479178 UPF3B; regulator of nonsense transcripts 3B isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"100477603 TRIM21; E3 ubiquitin-protein ligase TRIM21 isoform X2\tK10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]"
					},
					{
						"name":"100478070 TRIM71; E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
					},
					{
						"name":"100482703 POLR2G; LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"100469151 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]"
					},
					{
						"name":"100473108 ZAR1L; ZAR1-like protein isoform X1\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"105236616 ZAR1; zygote arrest protein 1\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"100480771 YTHDF1; YTH domain-containing family protein 1\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"100481471 YTHDF2; YTH domain-containing family protein 2\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"100482397 YTHDF3; YTH domain-containing family protein 3 isoform X3\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"100480982 TIAL1; nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"100484078 TIA1; nucleolysin TIA-1 isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"100465799 PABPC4; LOW QUALITY PROTEIN: polyadenylate-binding protein 4\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100466038 LOW QUALITY PROTEIN: polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100475370 polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100480222 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100482395 PABPC5; polyadenylate-binding protein 5\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100482751 PABPC4L; polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100483251 PABPC1L; polyadenylate-binding protein 1-like isoform X2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100466791 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X7\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"100470208 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X2\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"100467605 FXR2; fragile X mental retardation syndrome-related protein 2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100471726 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100472255 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100475455 ZBP1; Z-DNA-binding protein 1 isoform X2\tK12965 ZBP1; Z-DNA binding protein 1"
					},
					{
						"name":"100468848 ELAVL1; ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"100470608 G3BP1; ras GTPase-activating protein-binding protein 1\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"100468331 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"100481938 EIF2A; eukaryotic translation initiation factor 2A isoform X1\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"100466854 EIF4A1; eukaryotic initiation factor 4A-I\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"100481978 EIF4A2; eukaryotic initiation factor 4A-II isoform X2\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"100477327 EIF4A3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"100466347 EIF4B; eukaryotic translation initiation factor 4B isoform X4\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"100465360 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X6\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100470670 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100478604 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100464040 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"100470572 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X7\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"100474764 RPS6KA6; ribosomal protein S6 kinase alpha-6\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"100483843 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"100466625 RACK1; receptor of activated protein C kinase 1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"117800066 receptor of activated protein C kinase 1-like\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"100474087 TRAF2; TNF receptor-associated factor 2\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
					},
					{
						"name":"100470225 LOW QUALITY PROTEIN: nuclear RNA export factor 2\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100481947 NXF1; nuclear RNA export factor 1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100484912 nuclear RNA export factor 2-like isoform X1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"105234339 LOW QUALITY PROTEIN: nuclear RNA export factor 3\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100478725 HDAC6; histone deacetylase 6 isoform X1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					},
					{
						"name":"100476453 TDRD3; tudor domain-containing protein 3 isoform X1\tK18404 TDRD3; tudor domain-containing protein 3"
					},
					{
						"name":"100474905 LARP4; la-related protein 4 isoform X1\tK18763 LARP4; la-related protein 4"
					},
					{
						"name":"100483616 LARP4B; la-related protein 4B isoform X1\tK18763 LARP4; la-related protein 4"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"100481669 DCP1A; mRNA-decapping enzyme 1A isoform X1\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"100479967 DCP1B; mRNA-decapping enzyme 1B isoform X1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"100473528 DCP2; m7GpppN-mRNA hydrolase isoform X1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"100477267 DDX6; probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"100473281 EDC3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"100468074 EDC4; enhancer of mRNA-decapping protein 4 isoform X2\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"100483301 PATL1; protein PAT1 homolog 1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"100470506 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"100483807 LSM2; U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"100473950 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"100477624 LSM4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"100472616 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"100477883 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"100465685 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"100479478 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"100464646 XRN1; 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"100468930 XRN2; 5'-3' exoribonuclease 2 isoform X1\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"100482941 NUDT16; U8 snoRNA-decapping enzyme\tK16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]"
					},
					{
						"name":"117795062 U8 snoRNA-decapping enzyme-like\tK16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"100470542 DCPS; m7GpppX diphosphatase isoform X1\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"100481272 HELZ; probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"100479652 EXOSC1; exosome complex component CSL4\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"100466226 EXOSC2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"100473928 EXOSC3; exosome complex component RRP40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"100473642 EXOSC4; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"100484369 EXOSC5; exosome complex component RRP46 isoform X1\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"117795089 EXOSC6; exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"100484320 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"100466704 EXOSC8; exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"100482524 EXOSC9; exosome complex component RRP45 isoform X1\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"100465639 DIS3; exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"100483820 DIS3L; DIS3-like exonuclease 1 isoform X2\tK18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"100467172 EXOSC10; exosome component 10\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"100468183 C1D; nuclear nucleic acid-binding protein C1D\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"100482750 MPHOSPH6; M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type"
					},
					{
						"name":"100481165 DDX60; probable ATP-dependent RNA helicase DDX60 isoform X1\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"100468731 TENT4B; terminal nucleotidyltransferase 4B\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"100472944 TENT4A; terminal nucleotidyltransferase 4A isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"100474889 ZCCHC7; zinc finger CCHC domain-containing protein 7 isoform X1\tK12597 AIR1_2; protein AIR1\/2"
					},
					{
						"name":"100479623 MTREX; exosome RNA helicase MTR4 isoform X1\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"100475276 SKIV2L; helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"100479521 TTC37; tetratricopeptide repeat protein 37 isoform X1\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"100480255 WDR61; WD repeat-containing protein 61\tK12602 WDR61; WD repeat-containing protein 61"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"100474935 CNOT6L; CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"100478261 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"100474169 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X4\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"100483517 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"100464278 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"100473214 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X3\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"100473287 CNOT7; CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"100474446 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"100481156 CNOT9; CCR4-NOT transcription complex subunit 9\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"100475317 CNOT10; CCR4-NOT transcription complex subunit 10\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"100471669 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X7\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"100483709 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"100469832 PARN; LOW QUALITY PROTEIN: poly(A)-specific ribonuclease PARN\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"100478756 PNLDC1; poly(A)-specific ribonuclease PNLDC1 isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"100481192 DHX36; ATP-dependent DNA\/RNA helicase DHX36 isoform X1\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]"
					},
					{
						"name":"100467646 BTG3; protein BTG3\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100482458 TOB2; protein Tob2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100482779 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100483106 BTG4; protein BTG4\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100484707 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100484798 TOB1; protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100473502 uncharacterized protein LOC100473502\tK05427 CSF2; granulocyte-macrophage colony-stimulating factor"
					},
					{
						"name":"109488324 CSF2; granulocyte-macrophage colony-stimulating factor\tK05427 CSF2; granulocyte-macrophage colony-stimulating factor"
					},
					{
						"name":"100472917 NOCT; LOW QUALITY PROTEIN: nocturnin\tK18764 NOCT; nocturnin [EC:3.1.3.108]"
					},
					{
						"name":"100481634 ERI1; 3'-5' exoribonuclease 1 isoform X1\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"100466195 ERI2; ERI1 exoribonuclease 2\tK18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]"
					},
					{
						"name":"100470542 DCPS; m7GpppX diphosphatase isoform X1\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"100480045 PDE12; 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]"
					},
					{
						"name":"100483768 IREB2; iron-responsive element-binding protein 2 isoform X2\tK22416 IREB2; iron-responsive element-binding protein 2"
					},
					{
						"name":"100481272 HELZ; probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					},
					{
						"name":"100464014 HELZ2; helicase with zinc finger domain 2\tK25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]"
					},
					{
						"name":"100483188 NRDE2; nuclear exosome regulator NRDE2\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"100465282 SAMD4B; protein Smaug homolog 2\tK27396 SMG; protein Smaug"
					},
					{
						"name":"100478913 SAMD4A; protein Smaug homolog 1 isoform X3\tK27396 SMG; protein Smaug"
					},
					{
						"name":"100476052 FOCAD; focadhesin isoform X2\tK27498 FOCAD; focadhesin"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases",
					"children":[
					{
						"name":"100467619 RNASE1; ribonuclease pancreatic\tK01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]"
					},
					{
						"name":"105234286 RNASE4; ribonuclease 4\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]"
					},
					{
						"name":"100468875 ribonuclease 7\tK01172 RNASE6_7_8; ribonuclease 6\/7\/8 [EC:3.1.27.-]"
					},
					{
						"name":"117797281 ribonuclease 7-like\tK01172 RNASE6_7_8; ribonuclease 6\/7\/8 [EC:3.1.27.-]"
					},
					{
						"name":"117797267 RNASE11; probable ribonuclease 11\tK16633 RNASE11; ribonuclease 11 [EC:3.1.27.-]"
					},
					{
						"name":"100466452 ZC3H12B; probable ribonuclease ZC3H12B\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"100473690 ZC3H12C; probable ribonuclease ZC3H12C isoform X1\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"100481016 ZC3H12A; endoribonuclease ZC3H12A\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"105238202 ZC3H12D; probable ribonuclease ZC3H12D isoform X1\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"100464911 DROSHA; ribonuclease 3 isoform X1\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"100475752 REXO2; oligoribonuclease, mitochondrial\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"100464368 ENO3; beta-enolase isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"100474299 ENO2; gamma-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"100476305 ENO1; alpha-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"117800325 alpha-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"117800431 beta-enolase-like isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"100474686 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
					},
					{
						"name":"100467584 PFKP; LOW QUALITY PROTEIN: ATP-dependent 6-phosphofructokinase, platelet type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"100471440 PFKM; ATP-dependent 6-phosphofructokinase, muscle type isoform X3\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"100479861 PFKL; ATP-dependent 6-phosphofructokinase, liver type isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"100483691 HSPA9; stress-70 protein, mitochondrial\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"100477321 HSPD1; 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"100466226 EXOSC2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"100479652 EXOSC1; exosome complex component CSL4\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"100473642 EXOSC4; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"100484320 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}
