{
	"name":"bthi03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"BTK_11115 methylated DNA-protein cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"BTK_14000 deoxyribodipyrimidine photolyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"BTK_28640 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"BTK_04980 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"BTK_03005 A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"BTK_09045 endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex"
					},
					{
						"name":"DNA polymerase epsilon complex"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex"
					},
					{
						"name":"Cul4-DDB2 complex"
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex"
					},
					{
						"name":"Cul4-CSA complex"
					},
					{
						"name":"Other TCR factor"
					}
					]
				},
				{
					"name":"TFIIH complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Other NER factors"
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"MutL homologs"
				},
				{
					"name":"DNA polymerase delta complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other MMR factors"
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex"
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex"
				},
				{
					"name":"BRCA complex"
				},
				{
					"name":"Shu complex and associated proteins"
				},
				{
					"name":"RecA family proteins"
				},
				{
					"name":"Rad52 family proteins"
				},
				{
					"name":"Rad54 family proteins"
				},
				{
					"name":"RecQ family DNA helicases"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Protein phosphatase 4"
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex"
				},
				{
					"name":"Other HR factors"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex"
				},
				{
					"name":"MRX complex"
				},
				{
					"name":"DNA Ligase 4 complex"
				},
				{
					"name":"X-family DNA polymerases"
				},
				{
					"name":"Other NHEJ factors"
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors"
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others"
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"B-family DNA polymerases"
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group"
			},
			{
				"name":"Other TLS factors"
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex"
			},
			{
				"name":"HRAD17(Rad24)-RFC complex"
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex"
			},
			{
				"name":"FPC (fork protection complex)"
			},
			{
				"name":"Triple T complex"
			},
			{
				"name":"BAG6-UBL4A-GET4 complex"
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases"
			},
			{
				"name":"Nucleases"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"PSO4 complex"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"BTK_03100 mutator MutT protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_03575 mutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_05265 phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_10130 phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_11160 MutT\/NUDIX family protein phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_14375 mutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_14470 mutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_16390 MutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_25150 MutT\/NUDIX family protein phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_27290 putative mutator MutT protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_30794 MutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"BTK_11115 methylated DNA-protein cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"BTK_19795 ADA regulatory protein\tK13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"BTK_19800 methylated DNA-protein cysteine methyltransferase\tK13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"BTK_14000 deoxyribodipyrimidine photolyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"BTK_28640 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"BTK_08955 uracil-DNA glycosylase\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"BTK_02835 DNA-3-methyladenine glycosylase II\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"BTK_19805 DNA-3-methyladenine glycosidase\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"BTK_04980 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"BTK_03005 A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"BTK_24065 formamidopyrimidine\/5-formyluracil\/5-hydroxymethyluracil DNA glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"BTK_09045 endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"BTK_22610 endonuclease IV\tK01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]"
					},
					{
						"name":"BTK_17450 deoxyribonuclease V\tK05982 nfi; deoxyribonuclease V [EC:3.1.21.7]"
					}
					]
				},
				{
					"name":"RecJ",
					"children":[
					{
						"name":"BTK_23240 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"BTK_01890 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"BTK_24070 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"BTK_27340 uvrA; excinuclease ABC subunit A\tK03701 uvrA; excinuclease ABC subunit A"
					},
					{
						"name":"BTK_27345 excinuclease ABC subunit B\tK03702 uvrB; excinuclease ABC subunit B"
					},
					{
						"name":"BTK_23720 uvrC; excinuclease ABC subunit C\tK03703 uvrC; excinuclease ABC subunit C"
					},
					{
						"name":"BTK_01885 ATP-dependent DNA helicase PcrA\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_06025 UvrD\/Rep family helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_07430 ATP-dependent DNA helicase, UvrD\/REP family protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_15725 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_30224 ATP-dependent DNA helicase PcrA\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_24070 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"BTK_01890 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)",
						"children":[
						{
							"name":"BTK_00515 rpoB; DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
						},
						{
							"name":"BTK_00520 DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"BTK_00700 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
						},
						{
							"name":"BTK_28270 DNA-directed RNA polymerase subunit delta\tK03048 rpoE; DNA-directed RNA polymerase subunit delta"
						},
						{
							"name":"BTK_20450 rpoZ; DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]"
						}
						]
					},
					{
						"name":"TRCF (transcription-repair coupling factor)",
						"children":[
						{
							"name":"BTK_00265 transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"BTK_19940 DNA mismatch repair protein MutS\tK03555 mutS; DNA mismatch repair protein MutS"
					},
					{
						"name":"BTK_18360 DNA mismatch repair protein mutS\tK07456 mutS2; DNA mismatch repair protein MutS2"
					},
					{
						"name":"BTK_23890 recombination and DNA strand exchange inhibitor protein\tK07456 mutS2; DNA mismatch repair protein MutS2"
					}
					]
				},
				{
					"name":"Molecular matchmaker",
					"children":[
					{
						"name":"BTK_19935 mutL; DNA mismatch repair protein\tK03572 mutL; DNA mismatch repair protein MutL"
					}
					]
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases",
					"children":[
					{
						"name":"BTK_22080 xseA; exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
					},
					{
						"name":"BTK_22075 exodeoxyribonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
					}
					]
				},
				{
					"name":"DNA polymerase III holoenzyme",
					"children":[
					{
						"name":"BTK_24160 dnaE; DNA polymerase III DnaE\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
					},
					{
						"name":"BTK_20175 polC; DNA polymerase III PolC\tK03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]"
					},
					{
						"name":"BTK_00010 DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"BTK_16355 DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"BTK_31936 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"BTK_22800 holA; DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
					},
					{
						"name":"BTK_00155 DNA polymerase III subunit delta'\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
					},
					{
						"name":"BTK_19120 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"BTK_00115 DNA polymerase III subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"BTK_01890 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"BTK_01885 ATP-dependent DNA helicase PcrA\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_06025 UvrD\/Rep family helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_07430 ATP-dependent DNA helicase, UvrD\/REP family protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_15725 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_30224 ATP-dependent DNA helicase PcrA\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"BTK_12080 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"BTK_29085 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"BTK_34676 hypothetical protein\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins",
					"children":[
					{
						"name":"BTK_23170 exodeoxyribonuclease v, alpha subunit\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"BTK_35141 helicase\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"BTK_35256 helicase RecD\/TraA\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"BTK_01675 recombinase A\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"BTK_19990 recA; recombinase A\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"BTK_23305 ruvA; Holliday junction DNA helicase RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"BTK_23300 Holliday junction DNA helicase B\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"BTK_20440 primosome assembly protein PriA\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
					},
					{
						"name":"BTK_12825 exonuclease\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"BTK_12820 nuclease sbcCD subunit D\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					}
					]
				},
				{
					"name":"RecFOR pathway proteins",
					"children":[
					{
						"name":"BTK_01675 recombinase A\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"BTK_19990 recA; recombinase A\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"BTK_00410 DNA repair protein RadA\tK04485 radA; DNA repair protein RadA\/Sms"
					},
					{
						"name":"BTK_00020 recF; recombination protein F\tK03629 recF; DNA replication and repair protein RecF"
					},
					{
						"name":"BTK_20370 ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					},
					{
						"name":"BTK_23240 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					},
					{
						"name":"BTK_22675 recO; DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
					},
					{
						"name":"BTK_00125 recR; recombination protein RecR\tK06187 recR; recombination protein RecR"
					},
					{
						"name":"BTK_22050 DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
					},
					{
						"name":"BTK_06725 penicillin-binding protein\tK03700 recU; recombination protein U"
					},
					{
						"name":"BTK_06735 penicillin-binding protein\tK03700 recU; recombination protein U"
					},
					{
						"name":"BTK_06755 hypothetical protein\tK03700 recU; recombination protein U"
					},
					{
						"name":"BTK_06835 penicillin-binding protein\tK03700 recU; recombination protein U"
					},
					{
						"name":"BTK_09060 recU; Holliday junction-specific endonuclease\tK03700 recU; recombination protein U"
					},
					{
						"name":"BTK_34831 recombination protein U (penicillin-binding protein-related factor A)\tK03700 recU; recombination protein U"
					},
					{
						"name":"BTK_23305 ruvA; Holliday junction DNA helicase RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"BTK_23300 Holliday junction DNA helicase B\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"AddAB pathway proteins",
					"children":[
					{
						"name":"BTK_06535 ATP-dependent nuclease subunit A\tK16898 addA; ATP-dependent helicase\/nuclease subunit A [EC:5.6.2.4 3.1.-.-]"
					},
					{
						"name":"BTK_06530 ATP-dependent nuclease subunit B\tK16899 addB; ATP-dependent helicase\/nuclease subunit B [EC:5.6.2.4 3.1.-.-]"
					}
					]
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins",
					"children":[
					{
						"name":"BTK_12825 exonuclease\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"BTK_12820 nuclease sbcCD subunit D\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex",
					"children":[
					{
						"name":"BTK_04690 Ku protein\tK10979 ku; DNA end-binding protein Ku"
					}
					]
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"BTK_00030 DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"BTK_00050 DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"BTK_00025 gyrB; DNA gyrase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						},
						{
							"name":"BTK_00045 gyrB; DNA gyrase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						},
						{
							"name":"BTK_20250 DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						},
						{
							"name":"BTK_32226 DNA topoisomerase 1\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						},
						{
							"name":"BTK_34451 DNA topoisomerase 1\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						}
						]
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"BTK_08840 DNA-binding protein HU\tK03530 hupB; DNA-binding protein HU-beta"
						},
						{
							"name":"BTK_12900 DNA-binding protein HupA\tK03530 hupB; DNA-binding protein HU-beta"
						},
						{
							"name":"BTK_19740 HU family DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta"
						},
						{
							"name":"BTK_30344 DNA-binding protein HU\tK03530 hupB; DNA-binding protein HU-beta"
						},
						{
							"name":"BTK_31351 DNA-binding protein HU\tK03530 hupB; DNA-binding protein HU-beta"
						}
						]
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway",
						"children":[
						{
							"name":"BTK_23240 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
						},
						{
							"name":"BTK_22675 recO; DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
						},
						{
							"name":"BTK_00125 recR; recombination protein RecR\tK06187 recR; recombination protein RecR"
						},
						{
							"name":"BTK_01890 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						}
						]
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"BTK_08710 ATP-dependent DNA helicase recQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"BTK_15715 ATP-dependent DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"BTK_27340 uvrA; excinuclease ABC subunit A\tK03701 uvrA; excinuclease ABC subunit A"
						},
						{
							"name":"BTK_27345 excinuclease ABC subunit B\tK03702 uvrB; excinuclease ABC subunit B"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"BTK_21895 DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"BTK_01675 recombinase A\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"BTK_19990 recA; recombinase A\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"BTK_06615 hypothetical protein\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"BTK_19595 LexA repressor\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"BTK_22050 DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"BTK_12080 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"BTK_29085 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"BTK_34676 hypothetical protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"BTK_02975 recX; recombination regulator RecX\tK03565 recX; regulatory protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase",
				"children":[
				{
					"name":"BTK_23895 hypothetical protein\tK02347 polX; DNA polymerase (family X)"
				}
				]
			},
			{
				"name":"DNA helicases",
				"children":[
				{
					"name":"BTK_09020 bifunctional ATP-dependent DNA helicase\/DNA polymerase III subunit epsilon\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"BTK_09120 DinG family ATP-dependent helicase\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"BTK_03100 mutator MutT protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_03575 mutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_05265 phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_10130 phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_11160 MutT\/NUDIX family protein phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_14375 mutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_14470 mutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_16390 MutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_25150 MutT\/NUDIX family protein phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_27290 putative mutator MutT protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_30794 MutT\/nudix family protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"BTK_08060 ribonucleotide-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"BTK_08065 nrdF; ribonucleotide-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"BTK_24175 bifunctional oligoribonuclease and PAP phosphatase NrnA\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				}
				]
			}
			]
		}
		]
	}
	]
}
