{
	"name":"ehs03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"104504359 RNMT; mRNA cap guanine-N7 methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"104507118 cyclin-dependent kinase 7-like\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"104513900 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]"
					},
					{
						"name":"104502653 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]"
					},
					{
						"name":"104505330 FAM103A1; RNMT-activating mini protein\tK18708 FAM103A1; RNMT-activating mini protein"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"104513320 NCBP2; nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					},
					{
						"name":"104516003 LOW QUALITY PROTEIN: nuclear cap-binding protein subunit 2-like\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"104516211 NUDT21; cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					},
					{
						"name":"104504756 CPSF6; cleavage and polyadenylation specificity factor subunit 6\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"104503648 PCF11; pre-mRNA cleavage complex 2 protein Pcf11\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"104508740 CPSF2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"104502961 CPSF3; cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"104513122 CPSF4; cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"104513410 FIP1L1; pre-mRNA 3'-end-processing factor FIP1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"104516435 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"104509341 WDR82; WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"104512926 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase PP1-gamma catalytic subunit-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"104513988 PPP1CB; serine\/threonine-protein phosphatase PP1-beta catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"104515685 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"104508900 CSTF1; cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1"
					},
					{
						"name":"104515712 LOW QUALITY PROTEIN: cleavage stimulation factor subunit 2-like\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"104516966 CSTF3; cleavage stimulation factor subunit 3\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"104503781 small nuclear ribonucleoprotein-associated protein B'\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"104505028 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"104517158 LSM10; LOW QUALITY PROTEIN: U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10"
					},
					{
						"name":"104508740 CPSF2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"104502961 CPSF3; cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"104515712 LOW QUALITY PROTEIN: cleavage stimulation factor subunit 2-like\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"104509253 histone RNA hairpin-binding protein-like\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"104515915 SLBP; histone RNA hairpin-binding protein\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"104513530 CASP8AP2; CASP8-associated protein 2\tK25593 CASP8AP2; CASP8-associated protein 2"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"104508639 SUPT4H1; transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"104503352 METTL14; N6-adenosine-methyltransferase subunit METTL14\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"104516295 METTL4; methyltransferase-like protein 4\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]"
					},
					{
						"name":"104505578 LOW QUALITY PROTEIN: methyltransferase-like protein 16\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"104504890 WTAP; pre-mRNA-splicing regulator WTAP\tK22824 WTAP; pre-mRNA-splicing regulator WTAP"
					},
					{
						"name":"104511915 KIAA1429; protein virilizer homolog\tK22910 VIRMA; protein virilizer"
					},
					{
						"name":"104516855 RBM15B; putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"104510494 ZC3H13; LOW QUALITY PROTEIN: zinc finger CCCH domain-containing protein 13\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"104513943 CBLL1; E3 ubiquitin-protein ligase Hakai\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"104502623 poly(A) polymerase alpha\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"104512542 PAPD4; poly(A) RNA polymerase GLD2\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"104506317 BARD1; LOW QUALITY PROTEIN: BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"104510419 RBM26; RNA-binding protein 26\tK13192 RBM26; RNA-binding protein 26"
					},
					{
						"name":"104514042 FTO; alpha-ketoglutarate-dependent dioxygenase FTO\tK19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"104504501 ALKBH5; RNA demethylase ALKBH5\tK10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"104506388 TARDBP; LOW QUALITY PROTEIN: TAR DNA-binding protein 43\tK23600 TARDBP; TAR DNA-binding protein 43"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"104502975 DHX40; probable ATP-dependent RNA helicase DHX40\tK18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]"
				},
				{
					"name":"104502857 KIN; DNA\/RNA-binding protein KIN17\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"104514303 METTL8; methyltransferase-like protein 8\tK24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]"
				},
				{
					"name":"104511581 METTL22; methyltransferase-like protein 22\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]"
				},
				{
					"name":"104507400 FAM46A; protein FAM46A\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"104508073 FAM46C; protein FAM46C\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]"
				},
				{
					"name":"104505371 protein FAM46C-like\tK23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]"
				},
				{
					"name":"104502940 ZC3H14; zinc finger CCCH domain-containing protein 14\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"104517117 protein mago nashi homolog\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"104503672 EIF4A3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"104503849 CCDC174; coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"104505926 CASC3; LOW QUALITY PROTEIN: protein CASC3\tK14323 CASC3; protein CASC3"
					},
					{
						"name":"104504443 SAP18; histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"104511004 PNN; pinin\tK13114 PNN; pinin"
					},
					{
						"name":"104504645 RNPS1; RNA-binding protein with serine-rich domain 1\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"104505458 SRRM1; serine\/arginine repetitive matrix protein 1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"104502524 THOC1; THO complex subunit 1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"104509820 THOC2; THO complex subunit 2\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"104505593 THOC3; THO complex subunit 3\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"104505626 THOC5; THO complex subunit 5 homolog\tK13174 THOC5; THO complex subunit 5"
					},
					{
						"name":"104515677 THOC7; THO complex subunit 7 homolog isoform X1\tK13176 THOC7; THO complex subunit 7"
					},
					{
						"name":"104512717 CHTOP; chromatin target of PRMT1 protein isoform X1\tK28424 CHTOP; chromatin target of PRMT1 protein"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"104505677 PCID2; PCI domain-containing protein 2\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"104512922 SHFM1; 26S proteasome complex subunit DSS1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"104514329 ENY2; transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"104514888 LOW QUALITY PROTEIN: centrin-2-like\tK10840 CETN2; centrin-2"
					},
					{
						"name":"104515020 centrin-3-like\tK16466 CETN3; centrin-3"
					},
					{
						"name":"104515653 MCM3AP; germinal-center associated nuclear protein\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"104507837 TPR; nucleoprotein TPR\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"104503000 RAE1; mRNA export factor\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"104516552 SEC13; protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"104511538 NUP37; nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37"
					},
					{
						"name":"104503276 NUP85; nuclear pore complex protein Nup85\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"104503782 NUP43; nucleoporin Nup43\tK14305 NUP43; nuclear pore complex protein Nup43"
					},
					{
						"name":"104513052 NUP50; nuclear pore complex protein Nup50\tK14295 NUP50; nuclear pore complex protein Nup50"
					},
					{
						"name":"104506343 NUP54; LOW QUALITY PROTEIN: nucleoporin p54\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"104514281 NUP88; nuclear pore complex protein Nup88\tK14318 NUP88; nuclear pore complex protein Nup88"
					},
					{
						"name":"104509797 NUP93; nuclear pore complex protein Nup93\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"104503074 NUP107; nuclear pore complex protein Nup107\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"104512373 NUP188; nucleoporin NUP188 homolog\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"104512944 nuclear pore complex protein Nup153-like\tK14296 NUP153; nuclear pore complex protein Nup153"
					},
					{
						"name":"104513218 NUP155; nuclear pore complex protein Nup155 isoform X1\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"104516811 NUP160; nuclear pore complex protein Nup160\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"104506369 NUP35; nucleoporin NUP53\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"104510439 LOW QUALITY PROTEIN: nucleoporin NUP53-like\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"104506072 NUP205; nuclear pore complex protein Nup205\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"104502510 NUP210; nuclear pore membrane glycoprotein 210\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"104515354 NUP214; nuclear pore complex protein Nup214\tK14317 NUP214; nuclear pore complex protein Nup214"
					},
					{
						"name":"104515090 NUPL2; nucleoporin-like protein 2\tK14321 NUPL2; nucleoporin-like protein 2"
					},
					{
						"name":"104503414 NDC1; nucleoporin NDC1\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"104503706 SEH1L; nucleoporin SEH1\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"104509010 RANBP2; E3 SUMO-protein ligase RanBP2\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
					},
					{
						"name":"104509033 sentrin-specific protease 2-like\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
					},
					{
						"name":"104515020 centrin-3-like\tK16466 CETN3; centrin-3"
					},
					{
						"name":"104506756 GLE1; nucleoporin GLE1\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"104502893 NTF2-related export protein 2\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"104508362 RAN; GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"104504606 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B"
					},
					{
						"name":"104514157 ELAVL1; ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"104514917 ELAVL4; ELAV-like protein 4 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"104515613 ELAVL2; ELAV-like protein 2 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"104506799 FAF2; FAS-associated factor 2\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"104502621 VCP; transitional endoplasmic reticulum ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"104516658 XPO1; exportin-1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"104517098 XPO7; exportin-7\tK18460 XPO7; exportin-7"
					},
					{
						"name":"104503426 ran-binding protein 17-like\tK24115 RANBP17; Ran-binding protein 17"
					},
					{
						"name":"104515193 RANGAP1; ran GTPase-activating protein 1\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"104503690 TAF15; TATA-binding protein-associated factor 2N\tK14651 TAF15; transcription initiation factor TFIID subunit 15"
					},
					{
						"name":"104505261 NUTF2; nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"104503003 eukaryotic translation initiation factor 4E-like\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"104504189 EIF4E2; eukaryotic translation initiation factor 4E type 2\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"104505005 EIF4E; eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"104509461 EIF4A2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"104503601 EIF4G2; eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"104511840 EIF4G1; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"104517254 EIF4G3; eukaryotic translation initiation factor 4 gamma 3\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"104507025 EIF4H; eukaryotic translation initiation factor 4H\tK24086 EIF4H; translation initiation factor 4H"
					},
					{
						"name":"104508995 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1"
					},
					{
						"name":"104505673 EIF4ENIF1; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E transporter\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"104504342 ANGEL1; protein angel homolog 1\tK18729 ANGEL; protein angel"
					},
					{
						"name":"104508838 ANGEL2; protein angel homolog 2 isoform X1\tK18729 ANGEL; protein angel"
					},
					{
						"name":"104506141 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"104513706 cytoplasmic FMR1-interacting protein 2\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"104511481 GEMIN5; LOW QUALITY PROTEIN: gem-associated protein 5\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"104510803 TACC3; transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"104505467 CPEB4; cytoplasmic polyadenylation element-binding protein 4\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"104517347 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"104511949 ATP-dependent RNA helicase DDX3X\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"104509376 GIGYF2; LOW QUALITY PROTEIN: PERQ amino acid-rich with GYF domain-containing protein 2\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"104506119 PABPC4; polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"104512389 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"104505325 PAIP2; polyadenylate-binding protein-interacting protein 2\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"104506005 PAIP2B; polyadenylate-binding protein-interacting protein 2B\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"104515243 DEAF1; deformed epidermal autoregulatory factor 1 homolog\tK23041 DEAF1; deformed epidermal autoregulatory factor 1"
					},
					{
						"name":"104504252 MCTS1; malignant T-cell-amplified sequence 1\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"104504433 DENR; density-regulated protein\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex",
					"children":[
					{
						"name":"104513938 C->U-editing enzyme APOBEC-1-like\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"104515546 C->U-editing enzyme APOBEC-1-like\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"104510863 A1CF; APOBEC1 complementation factor isoform X1\tK24978 A1CF; APOBEC1 complementation factor"
					}
					]
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"104508928 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"104504892 LOW QUALITY PROTEIN: RNA-binding protein Musashi homolog 1-like\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"104509217 DAZAP1; DAZ-associated protein 1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"104503952 HBS1L; HBS1-like protein\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"104512628 uncharacterized protein LOC104512628\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"104508207 PELO; protein pelota homolog\tK06965 PELO; protein pelota"
					},
					{
						"name":"104508370 embryonic polyadenylate-binding protein 2-B-like\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"104507973 ATP-dependent RNA helicase DDX19B isoform X1\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"104512468 LOW QUALITY PROTEIN: ATP-dependent RNA helicase DDX25-like\tK18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]"
					},
					{
						"name":"104511746 RCC1; LOW QUALITY PROTEIN: regulator of chromosome condensation\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"104505381 LARP6; la-related protein 6\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"104509833 la-related protein 6-like\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"104504510 POLDIP3; LOW QUALITY PROTEIN: polymerase delta-interacting protein 3\tK22414 POLDIP3; polymerase delta-interacting protein 3"
					},
					{
						"name":"104507227 zinc finger CCCH domain-containing protein 11A-like\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"104504179 protein PAT1 homolog 2-like\tK24823 PATL2; protein PAT1 homolog 2"
					},
					{
						"name":"104505418 UAP56-interacting factor-like\tK28772 FYTTD1; UAP56-interacting factor"
					},
					{
						"name":"104512500 FYTTD1; UAP56-interacting factor\tK28772 FYTTD1; UAP56-interacting factor"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"104506442 ETF1; eukaryotic peptide chain release factor subunit 1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"104503670 eukaryotic peptide chain release factor GTP-binding subunit ERF3A\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"104503574 UPF1; regulator of nonsense transcripts 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"104505432 UPF2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"104504192 UPF3B; regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"104515263 UPF3A; regulator of nonsense transcripts 3A\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"104504972 serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform-like\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"104512390 PPP2CA; serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"104506437 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"104508102 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform-like\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"104511010 PPP2R2A; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"104503425 PPP2R3C; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"104508243 PPP2R3B; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"104514796 PPP2R3A; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"104509127 PPP2R5A; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"104510255 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"104514576 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"104506906 SMG1; serine\/threonine-protein kinase SMG1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"104512853 SMG6; LOW QUALITY PROTEIN: telomerase-binding protein EST1A\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"104513882 SMG7; LOW QUALITY PROTEIN: protein SMG7\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"104506850 SMG8; protein SMG8\tK18734 SMG8; protein SMG8"
					},
					{
						"name":"104509376 GIGYF2; LOW QUALITY PROTEIN: PERQ amino acid-rich with GYF domain-containing protein 2\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"104505845 SECISBP2; selenocysteine insertion sequence-binding protein 2\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"104513967 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"104514750 GTPBP1; GTP-binding protein 1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"104512234 pumilio domain-containing protein KIAA0020 homolog\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"104507296 unconventional myosin-Vb-like\tK10357 MYO5; myosin V"
					},
					{
						"name":"104513638 MYO5A; unconventional myosin-Va\tK10357 MYO5; myosin V"
					},
					{
						"name":"104511953 BICD1; protein bicaudal D homolog 1\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"104513284 BICD2; protein bicaudal D homolog 2\tK18739 BICD; protein bicaudal D"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals",
					"children":[
					{
						"name":"104505299 actin, cytoplasmic type 5 isoform X1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"104515004 MBP; myelin basic protein isoform X1\tK17269 MBP; myelin basic protein"
					},
					{
						"name":"104516806 VIM; vimentin\tK07606 VIM; vimentin"
					},
					{
						"name":"104503569 GDF3; growth\/differentiation factor 3\tK05495 GDF1; growth differentiation factor 1"
					},
					{
						"name":"104517368 T-box-containing protein TBX6L\tK10180 TBX6; T-box protein 6"
					}
					]
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"104502841 FUBP3; far upstream element-binding protein 3\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"104513204 FUBP1; far upstream element-binding protein 1\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"104504385 EEF1A2; elongation factor 1-alpha 2\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"104508715 EEF1A1; elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"104503961 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2\/B1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1"
					},
					{
						"name":"104504399 AGFG1; arf-GAP domain and FG repeat-containing protein 1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1"
					},
					{
						"name":"104510664 double-stranded RNA-binding protein Staufen homolog 2-like\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"104513567 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"104513825 PTBP1; polypyrimidine tract-binding protein 1\tK13218 PTBP1; polypyrimidine tract-binding protein 1"
					},
					{
						"name":"104505467 CPEB4; cytoplasmic polyadenylation element-binding protein 4\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"104517347 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"104506141 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"104513706 cytoplasmic FMR1-interacting protein 2\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"104508487 poly(rC)-binding protein 3-like\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"104508616 PCBP3; poly(rC)-binding protein 3\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"104510970 caprin-1-like\tK18743 CAPRIN1; caprin-1"
					},
					{
						"name":"104503298 CAPRIN2; caprin-2 isoform X1\tK18744 CAPRIN2; caprin-2"
					},
					{
						"name":"104515558 YBX1; LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1\tK09276 YBX1; Y-box-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"104505815 XRN1; 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"104503532 AGO4; protein argonaute-4\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"104509760 LOW QUALITY PROTEIN: protein argonaute-2-like\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"104510424 AGO3; protein argonaute-3 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"104512770 protein argonaute-1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"104503003 eukaryotic translation initiation factor 4E-like\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"104504189 EIF4E2; eukaryotic translation initiation factor 4E type 2\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"104505005 EIF4E; eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"104503574 UPF1; regulator of nonsense transcripts 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"104511949 ATP-dependent RNA helicase DDX3X\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"104515461 DDX6; probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"104505752 LOW QUALITY PROTEIN: RNA-binding E3 ubiquitin-protein ligase MEX3C-like\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"104503728 LSM14A; protein LSM14 homolog A\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"104506493 LSM14B; protein LSM14 homolog B\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"104515558 YBX1; LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"104513938 C->U-editing enzyme APOBEC-1-like\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"104515546 C->U-editing enzyme APOBEC-1-like\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"104505177 PNRC2; proline-rich nuclear receptor coactivator 2\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2"
					},
					{
						"name":"104506906 SMG1; serine\/threonine-protein kinase SMG1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"104512853 SMG6; LOW QUALITY PROTEIN: telomerase-binding protein EST1A\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"104513882 SMG7; LOW QUALITY PROTEIN: protein SMG7\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"104512123 protein lin-28 homolog A-like\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"104517236 LOW QUALITY PROTEIN: protein lin-28 homolog B-like\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"104509107 HTT; huntingtin\tK04533 HD; huntingtin"
					},
					{
						"name":"104514158 IPO8; importin-8\tK18755 IPO8; importin-8"
					},
					{
						"name":"104512988 BICC1; protein bicaudal C homolog 1\tK18756 BICC1; protein bicaudal C"
					},
					{
						"name":"104508928 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"104506854 cAMP-dependent protein kinase catalytic subunit beta\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"104503958 LARP1B; LOW QUALITY PROTEIN: la-related protein 1B\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"104517265 LARP1; LOW QUALITY PROTEIN: la-related protein 1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"104516649 ATXN2; ataxin-2\tK23625 ATXN2; ataxin-2"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"104516461 DCP2; m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"104508226 DCP1A; LOW QUALITY PROTEIN: mRNA-decapping enzyme 1A\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"104507683 DCP1B; LOW QUALITY PROTEIN: mRNA-decapping enzyme 1B\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"104514389 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"104508839 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"104506367 LSM4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"104503250 LSM5; U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"104505319 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"104516118 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"104505199 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"104514316 KLC1; kinesin light chain 1 isoform X1\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"104514672 kinesin light chain 1-like\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"104507296 unconventional myosin-Vb-like\tK10357 MYO5; myosin V"
					},
					{
						"name":"104513638 MYO5A; unconventional myosin-Va\tK10357 MYO5; myosin V"
					},
					{
						"name":"104504454 tubulin alpha-3 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"104504589 tubulin alpha-8 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"104514915 TUBA8; tubulin alpha-8 chain isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"104505467 CPEB4; cytoplasmic polyadenylation element-binding protein 4\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"104517347 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"104511481 GEMIN5; LOW QUALITY PROTEIN: gem-associated protein 5\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"104510803 TACC3; transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"104503966 TNRC6C; trinucleotide repeat-containing gene 6C protein\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"104514987 TNRC6A; trinucleotide repeat-containing gene 6A protein\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"104516335 LOW QUALITY PROTEIN: trinucleotide repeat-containing gene 6B protein-like\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"104505678 LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 1-like\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"104515457 CNOT2; CCR4-NOT transcription complex subunit 2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"104506199 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"104503143 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"104503809 CNOT6; CCR4-NOT transcription complex subunit 6\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"104511482 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"104514466 CNOT7; CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"104517348 uncharacterized protein KIAA0355 homolog\tK26671 GARRE1; granule associated Rac and RHOG effector protein 1"
					},
					{
						"name":"104506040 DIS3L2; DIS3-like exonuclease 2\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"104510512 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"104502851 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104502861 protein BTG1-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104508676 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104512517 TOB1; protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104512826 BTG4; protein BTG4\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104516815 TOB2; protein Tob2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104505673 EIF4ENIF1; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E transporter\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"104515805 EDC3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"104514656 EDC4; enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"104505432 UPF2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"104504192 UPF3B; regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"104515263 UPF3A; regulator of nonsense transcripts 3A\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"104510380 TRIM71; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
					},
					{
						"name":"104506985 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]"
					},
					{
						"name":"104504619 ZAR1L; ZAR1-like protein\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"104505088 YTHDF1; YTH domain-containing family protein 1\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"104505152 YTHDF3; YTH domain-containing family protein 3 isoform X1\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"104503844 nucleolysin TIAR\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"104506119 PABPC4; polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"104512389 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"104510664 double-stranded RNA-binding protein Staufen homolog 2-like\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"104513567 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"104506141 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"104514157 ELAVL1; ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"104506596 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"104503538 ras GTPase-activating protein-binding protein 2-like\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"104506099 EIF2A; eukaryotic translation initiation factor 2A\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"104503827 EIF3B; eukaryotic translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"104509461 EIF4A2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"104503672 EIF4A3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"104503601 EIF4G2; eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"104511840 EIF4G1; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"104517254 EIF4G3; eukaryotic translation initiation factor 4 gamma 3\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"104506377 RPS6KA6; ribosomal protein S6 kinase alpha-6\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"104507004 RPS6KA2; ribosomal protein S6 kinase alpha-2\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"104507490 RPS6KA1; ribosomal protein S6 kinase alpha-1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"104511743 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"104516843 guanine nucleotide-binding protein subunit beta-2-like 1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"104513443 TRAF2; TNF receptor-associated factor 2 isoform X1\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
					},
					{
						"name":"104509850 LARP4; LOW QUALITY PROTEIN: la-related protein 4\tK18763 LARP4; la-related protein 4"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"104508226 DCP1A; LOW QUALITY PROTEIN: mRNA-decapping enzyme 1A\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"104507683 DCP1B; LOW QUALITY PROTEIN: mRNA-decapping enzyme 1B\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"104516461 DCP2; m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"104515461 DDX6; probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"104515805 EDC3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"104514656 EDC4; enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"104514389 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"104508839 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"104506367 LSM4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"104503250 LSM5; U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"104505319 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"104516118 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"104505199 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"104505815 XRN1; 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"104510050 XRN2; 5'-3' exoribonuclease 2\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"104516455 DCPS; m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"104515581 HELZ; probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"104503178 EXOSC2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"104517184 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"104511113 EXOSC8; exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"104502974 EXOSC9; exosome complex component RRP45\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"104514892 DIS3; exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"104507419 DIS3L; DIS3-like exonuclease 1\tK18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"104512392 EXOSC10; exosome component 10\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"104503124 C1D; nuclear nucleic acid-binding protein C1D\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"104513555 MPHOSPH6; M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type"
					},
					{
						"name":"104507692 LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX60\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"104510993 PAPD7; non-canonical poly(A) RNA polymerase PAPD7 isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"104516820 PAPD5; non-canonical poly(A) RNA polymerase PAPD5\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"104512548 TTC37; tetratricopeptide repeat protein 37\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"104515831 WDR61; WD repeat-containing protein 61\tK12602 WDR61; WD repeat-containing protein 61"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"104503143 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"104503809 CNOT6; CCR4-NOT transcription complex subunit 6\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"104505678 LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 1-like\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"104515457 CNOT2; CCR4-NOT transcription complex subunit 2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"104506199 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"104511482 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"104514466 CNOT7; CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"104509631 RQCD1; cell differentiation protein RCD1 homolog\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"104502530 CNOT10; CCR4-NOT transcription complex subunit 10\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"104510512 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"104503037 PNLDC1; poly(A)-specific ribonuclease PARN-like domain-containing protein 1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"104510140 PARN; poly(A)-specific ribonuclease PARN\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"104513012 DHX36; ATP-dependent RNA helicase DHX36\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]"
					},
					{
						"name":"104502851 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104502861 protein BTG1-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104508676 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104512517 TOB1; protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104512826 BTG4; protein BTG4\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104516815 TOB2; protein Tob2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"104509053 CCRN4L; nocturnin\tK18764 NOCT; nocturnin [EC:3.1.3.108]"
					},
					{
						"name":"104511740 ERI1; 3'-5' exoribonuclease 1\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"104509182 ERI2; ERI1 exoribonuclease 2\tK18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]"
					},
					{
						"name":"104516455 DCPS; m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"104503466 PDE12; 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]"
					},
					{
						"name":"104517206 IREB2; iron-responsive element-binding protein 2\tK22416 IREB2; iron-responsive element-binding protein 2"
					},
					{
						"name":"104515581 HELZ; probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					},
					{
						"name":"104507684 HELZ2; helicase with zinc finger domain 2\tK25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]"
					},
					{
						"name":"104510566 protein NRDE2 homolog\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"104512732 SAMD4A; protein Smaug homolog 1\tK27396 SMG; protein Smaug"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases",
					"children":[
					{
						"name":"104505065 ZC3H12C; probable ribonuclease ZC3H12C\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"104505974 ZC3H12D; probable ribonuclease ZC3H12D\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"104507009 ribonuclease ZC3H12A-like\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"104514986 ZC3H12B; probable ribonuclease ZC3H12B\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"104507213 DROSHA; ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"104507083 REXO2; oligoribonuclease, mitochondrial\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"104504150 ENO1; alpha-enolase isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"104516419 gamma-enolase isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"104503147 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
					},
					{
						"name":"104506621 PFKP; LOW QUALITY PROTEIN: ATP-dependent 6-phosphofructokinase, platelet type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"104517395 ATP-dependent 6-phosphofructokinase, liver type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"104512137 HSPA9; stress-70 protein, mitochondrial\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"104503627 HSPD1; 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"104503178 EXOSC2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"104517184 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}