{
	"name":"msa03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"Mycsm_02288 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"Mycsm_04405 oligoribonuclease (3'->5' exoribonuclease)\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"Mycsm_04088 GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"Mycsm_04205 Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"Mycsm_02478 transcription termination factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"Mycsm_02803 NusB antitermination factor\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"Mycsm_00913 transcription antitermination protein nusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"Mycsm_05183 dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"Mycsm_02839 tRNA\/rRNA cytosine-C5-methylase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"Mycsm_02282 RNA methyltransferase, RsmD family\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"Mycsm_04093 RNA methyltransferase, RsmE family\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"Mycsm_06508 16S rRNA m(7)G-527 methyltransferase\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Mycsm_03869 S-adenosyl-methyltransferase MraW\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"Mycsm_05207 putative S-adenosylmethionine-dependent methyltransferase, YraL family\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"Mycsm_03110 hemolysin A\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"Mycsm_05887 rRNA methylase, putative, group 3\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"Mycsm_02375 23S rRNA m(2)A-2503 methyltransferase\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"Mycsm_03110 hemolysin A\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				},
				{
					"name":"Mycsm_01289 23S RNA-specific pseudouridylate synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"Mycsm_03123 pseudouridine synthase family protein\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"Mycsm_02929 ribosomal large subunit pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"Mycsm_01112 ribosomal-protein-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"Mycsm_05249 acetyltransferase, ribosomal protein N-acetylase\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"Mycsm_02308 16S rRNA processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"Mycsm_02288 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"Mycsm_04208 ribonuclease, Rne\/Rng family\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"Mycsm_02788 RNAse H-fold protein YqgF\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"Mycsm_04828 DNA\/RNA helicase, superfamily II\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"Mycsm_04088 GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"Mycsm_01407 ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"Mycsm_03125 ribosome-associated GTPase EngA\tK03977 engA; GTPase"
			},
			{
				"name":"Mycsm_04205 Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"Mycsm_02569 GTP-binding protein HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"Mycsm_04721 translation factor SUA5\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"Mycsm_02733 (p)ppGpp synthetase, RelA\/SpoT family\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"Mycsm_02481 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"Mycsm_02477 hypothetical protein\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"Mycsm_04191 iojap-like ribosome-associated protein\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"Mycsm_04091 metalloprotein, YbeY\/UPF0054 family\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"Mycsm_05031 GTP-binding protein YchF\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"Mycsm_02287 putative metal-binding protein, possibly nucleic-acid binding protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}