{
	"name":"pbi03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"103054500 MGMT; methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"103067031 ALKBH2; DNA oxidative demethylase ALKBH2\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"103049891 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"103065287 ASCC3; activating signal cointegrator 1 complex subunit 3\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				},
				{
					"name":"103067349 deoxyribodipyrimidine photo-lyase-like\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"103057544 UNG; uracil-DNA glycosylase isoform X1\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"103052255 CCNO; cyclin-O\tK10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]"
					},
					{
						"name":"103058406 TDG; G\/T mismatch-specific thymine DNA glycosylase isoform X2\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"103052134 MPG; DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"103060135 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"103061782 MUTYH; adenine DNA glycosylase isoform X3\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"103051872 MBD4; methyl-CpG-binding domain protein 4 isoform X1\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"103056383 OGG1; N-glycosylase\/DNA lyase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"103056109 NEIL1; endonuclease 8-like 1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"103052360 NEIL2; endonuclease 8-like 2 isoform X1\tK10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"103056400 NEIL3; endonuclease 8-like 3\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"103048346 NTHL1; endonuclease III-like protein 1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"103049845 APEX1; DNA-(apurinic or apyrimidinic site) lyase\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"103059473 APEX2; DNA-(apurinic or apyrimidinic site) lyase 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"103054637 POLD1; DNA polymerase delta catalytic subunit isoform X2\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"103061070 POLD2; DNA polymerase delta subunit 2 isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"103061468 POLD3; DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"103062790 POLD4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"103049755 POLE; DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"103052002 DNA polymerase epsilon subunit 2\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"103058852 DNA polymerase epsilon subunit 2\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"103067387 POLE3; DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"103055444 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"103053156 flap endonuclease 1-like\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"103063759 FEN1; flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"103064233 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"103066680 POLB; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"103053968 XRCC1; DNA repair protein XRCC1 isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"103062651 short transient receptor potential channel 2-like\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"103050660 LIG3; DNA ligase 3 isoform X1\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"103064074 TDP1; tyrosyl-DNA phosphodiesterase 1 isoform X1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"103066205 APTX; aprataxin isoform X3\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"103055773 APLF; aprataxin and PNK-like factor\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"103056785 PNKP; bifunctional polynucleotide phosphatase\/kinase\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"103050122 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"103062692 POLL; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"103053160 PARP1; poly [ADP-ribose] polymerase 1 isoform X1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"103057054 PARP2; poly [ADP-ribose] polymerase 2 isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"103048840 PARP3; poly [ADP-ribose] polymerase 3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"103049367 poly [ADP-ribose] polymerase 4\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"103056870 XPC; DNA repair protein complementing XP-C cells isoform X1\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"103057994 RAD23A; UV excision repair protein RAD23 homolog A isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"103061094 RAD23B; UV excision repair protein RAD23 homolog B isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"103061688 CETN2; centrin-2\tK10840 CETN2; centrin-2"
						},
						{
							"name":"103063412 centrin-2-like\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"103065423 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"103054675 CUL4B; cullin-4B\tK10609 CUL4; cullin 4"
						},
						{
							"name":"103056431 DDB1; DNA damage-binding protein 1 isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"103059573 DDB2; DNA damage-binding protein 2\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"103060884 POLR2A; DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"103055368 POLR2B; DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"103054596 POLR2C; DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"103066577 POLR2D; DNA-directed RNA polymerase II subunit RPB4 isoform X1\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"103062569 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"103053228 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"103067278 POLR2G; DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"103062347 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"107326288 POLR2I; DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"107326298 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"103067977 POLR2J; DNA-directed RNA polymerase II subunit RPB11-a isoform X1\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"103051493 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"103065423 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"103054675 CUL4B; cullin-4B\tK10609 CUL4; cullin 4"
						},
						{
							"name":"103056431 DDB1; DNA damage-binding protein 1 isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"103055046 ERCC8; DNA excision repair protein ERCC-8 isoform X3\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"103055956 ERCC6; DNA excision repair protein ERCC-6 isoform X2\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"103062240 UVSSA; UV-stimulated scaffold protein A\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"103057500 ELOF1; transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"103049028 ERCC3; general transcription and DNA repair factor IIH helicase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"103050318 ERCC2; general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"103058876 GTF2H1; general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"103062189 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"103054878 GTF2H3; general transcription factor IIH subunit 3\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"103061391 GTF2H4; general transcription factor IIH subunit 4 isoform X1\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"103052776 GTF2H5; general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"103057397 CDK7; cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"103061836 CCNH; cyclin-H\tK06634 CCNH; cyclin H"
					},
					{
						"name":"103058175 MNAT1; CDK-activating kinase assembly factor MAT1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"103054280 RPA1; replication protein A 70 kDa DNA-binding subunit isoform X1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"103054371 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"103051255 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"103067428 ERCC1; DNA excision repair protein ERCC-1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"103062375 ERCC4; DNA repair endonuclease XPF\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"103060755 ERCC5; DNA repair protein complementing XP-G cells\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"103064233 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"103051762 MMS19; MMS19 nucleotide excision repair protein homolog\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"103064975 CCDC117; coiled-coil domain-containing protein 117\tK27967 CCDC117; coiled-coil domain-containing protein 117"
					},
					{
						"name":"103061680 CIAO1; probable cytosolic iron-sulfur protein assembly protein CIAO1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"103048329 CIAO2B; mitotic spindle-associated MMXD complex subunit MIP18 isoform X1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"103056944 CUL3; cullin-3\tK03869 CUL3; cullin 3"
					},
					{
						"name":"103067405 CUL5; cullin-5 isoform X2\tK10612 CUL5; cullin 5"
					},
					{
						"name":"103067951 ELOC; elongin-C isoform X1\tK03872 ELOC; elongin-C"
					},
					{
						"name":"103053353 ELOB; elongin-B isoform X1\tK03873 ELOB; elongin-B"
					},
					{
						"name":"103066374 ELOA; elongin-A\tK15076 ELOA; elongin-A"
					},
					{
						"name":"103057907 UBAP2L; ubiquitin-associated protein 2-like\tK26545 UBAP2; ubiquitin-associated protein 2"
					},
					{
						"name":"103058147 UBAP2; ubiquitin-associated protein 2 isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"103057506 MSH2; DNA mismatch repair protein Msh2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"103064642 MSH3; DNA mismatch repair protein Msh3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"103056083 MSH6; DNA mismatch repair protein Msh6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"103059490 PMS1; PMS1 protein homolog 1 isoform X1\tK10864 PMS1; DNA mismatch repair protein PMS1"
					},
					{
						"name":"103056141 MLH1; DNA mismatch repair protein Mlh1 isoform X1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"103063489 PMS2; mismatch repair endonuclease PMS2\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"103067532 MLH3; DNA mismatch repair protein Mlh3 isoform X1\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"103054637 POLD1; DNA polymerase delta catalytic subunit isoform X2\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"103061070 POLD2; DNA polymerase delta subunit 2 isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"103061468 POLD3; DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"103062790 POLD4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"103054280 RPA1; replication protein A 70 kDa DNA-binding subunit isoform X1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"103054371 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"103051255 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"103054882 RFC1; replication factor C subunit 1 isoform X1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"103054137 RFC4; replication factor C subunit 4 isoform X2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"103055645 RFC2; replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"103050610 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"103050675 RFC3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"103055444 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"103048716 EXO1; exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"103050122 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"103064233 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"103060392 WDR76; WD repeat-containing protein 76 isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"103061835 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"103064733 DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"103053407 NBN; nibrin\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"103057262 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103065778 BRCA1-associated RING domain protein 1-like\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"103057262 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103049996 ABRAXAS1; BRCA1-A complex subunit Abraxas 1\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"103056971 UIMC1; BRCA1-A complex subunit RAP80 isoform X1\tK20775 UIMC1; BRCA1-A complex subunit RAP80"
					},
					{
						"name":"103053879 BABAM1; BRISC and BRCA1-A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"103058066 BABAM2; BRISC and BRCA1-A complex member 2 isoform X3\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"103055227 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X2\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"103057262 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103063956 BRIP1; Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"103055805 TOPBP1; DNA topoisomerase 2-binding protein 1 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"103057262 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103066696 RBBP8; DNA endonuclease RBBP8 isoform X1\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"103061835 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"103064733 DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"103053407 NBN; nibrin\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"103057262 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103068142 BRCA2; breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"103057917 PALB2; partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					},
					{
						"name":"103051032 RAD51; DNA repair protein RAD51 homolog 1 isoform X1\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"Shu complex and associated proteins",
					"children":[
					{
						"name":"103050083 ZSWIM7; zinc finger SWIM domain-containing protein 7 isoform X2\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"103059640 SWSAP1; ATPase SWSAP1 isoform X1\tK25771 SWSAP1; ATPase SWSAP1"
					},
					{
						"name":"103059388 SPIDR; DNA repair-scaffolding protein\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"103054645 PDS5A; sister chromatid cohesion protein PDS5 homolog A isoform X1\tK11267 PDS5; sister chromatid cohesion protein PDS5"
					},
					{
						"name":"103067443 PDS5B; sister chromatid cohesion protein PDS5 homolog B\tK11267 PDS5; sister chromatid cohesion protein PDS5"
					},
					{
						"name":"103049320 FIGNL1; fidgetin-like protein 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"103051032 RAD51; DNA repair protein RAD51 homolog 1 isoform X1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"103049986 RAD51B; DNA repair protein RAD51 homolog 2 isoform X1\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"103066402 RAD51C; DNA repair protein RAD51 homolog 3\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"103049994 RAD51D; DNA repair protein RAD51 homolog 4 isoform X1\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"103062407 XRCC2; DNA repair protein XRCC2\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"103058279 XRCC3; DNA repair protein XRCC3 isoform X1\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"103057289 RAD52; DNA repair protein RAD52 homolog isoform X1\tK10873 RAD52; DNA repair and recombination protein RAD52"
					},
					{
						"name":"103052352 RDM1; RAD52 motif-containing protein 1\tK10874 RDM1; RAD52 motif-containing protein 1"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"103048307 RAD54L; DNA repair and recombination protein RAD54-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"103063517 RAD54L2; helicase ARIP4\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"103062118 RAD54B; DNA repair and recombination protein RAD54B\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"103058665 RECQL; ATP-dependent DNA helicase Q1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"103066362 WRN; Werner syndrome ATP-dependent helicase\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"103060640 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"103060975 RECQL4; ATP-dependent DNA helicase Q4\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					},
					{
						"name":"103050220 RECQL5; ATP-dependent DNA helicase Q5 isoform X1\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"103060640 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"103052651 TOP3B; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"103060611 TOP3A; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"103054812 RMI1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"103054875 RMI2; recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"103054280 RPA1; replication protein A 70 kDa DNA-binding subunit isoform X1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"103054371 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"103051255 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"103060275 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"103054086 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"103065922 serine\/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X2\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"103065596 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"103048401 PPP4R3A; serine\/threonine-protein phosphatase 4 regulatory subunit 3A\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"103057311 serine\/threonine-protein phosphatase 4 regulatory subunit 3B isoform X2\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"103055913 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"103048723 AP5B1; AP-5 complex subunit beta-1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"103058356 AP5M1; AP-5 complex subunit mu-1\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"103067570 AP5Z1; AP-5 complex subunit zeta-1 isoform X1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"103059945 SMC5; structural maintenance of chromosomes protein 5 isoform X1\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"103049392 LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 6-like\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"103059613 structural maintenance of chromosomes protein 6-like\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"103067050 structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"103060206 FAM84A; protein FAM84A\tK22805 FAM84A; protein FAM84A"
					},
					{
						"name":"103062591 NSMCE1; non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"103059229 NSMCE2; LOW QUALITY PROTEIN: E3 SUMO-protein ligase NSE2\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"103058918 non-structural maintenance of chromosomes element 3 homolog isoform X1\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"103053685 non-structural maintenance of chromosomes element 4 homolog A isoform X1\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"103067534 SLF1; SMC5-SMC6 complex localization factor protein 1\tK26126 SLF1; SMC5-SMC6 complex localization factor protein 1"
					},
					{
						"name":"103054157 SLF2; SMC5-SMC6 complex localization factor protein 2 isoform X1\tK26127 SLF2; SMC5-SMC6 complex localization factor protein 2"
					},
					{
						"name":"103067503 SIMC1; SUMO-interacting motif-containing protein 1\tK28408 SIMC1; SUMO-interacting motif-containing protein 1"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"103066772 EME1; crossover junction endonuclease EME1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"103063955 EME2; probable crossover junction endonuclease EME2\tK10883 EME2; crossover junction endonuclease EME2"
					},
					{
						"name":"103053120 EXD2; exonuclease 3'-5' domain-containing protein 2\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"103048538 MUS81; crossover junction endonuclease MUS81 isoform X1\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"103062566 SEM1; LOW QUALITY PROTEIN: 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"103055306 SWI5; DNA repair protein SWI5 homolog isoform X2\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"103048999 SFR1; swi5-dependent recombination DNA repair protein 1 homolog isoform X2\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"103058046 structure-specific endonuclease subunit slx1 isoform X2\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"103063539 SLX4; structure-specific endonuclease subunit SLX4\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"103059865 GEN1; flap endonuclease GEN homolog 1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"103066721 spatacsin isoform X1\tK19026 SPG11; spatacsin"
					},
					{
						"name":"103059969 ZFYVE26; zinc finger FYVE domain-containing protein 26 isoform X1\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"103049306 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 isoform X1\tK28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1"
					},
					{
						"name":"103059098 MORF4L1; mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"103048109 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"103062739 FAM84B; protein FAM84B\tK22810 FAM84B; protein FAM84B"
					},
					{
						"name":"103050485 BRAT1; BRCA1-associated ATM activator 1 isoform X1\tK23112 BRAT1; BRCA1-associated ATM activator 1"
					},
					{
						"name":"103066614 CUNH21orf2; protein C21orf2 homolog\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"103048162 HDGFL2; hepatoma-derived growth factor-related protein 2\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"103061000 EMSY; BRCA2-interacting transcriptional repressor EMSY\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"103062001 HSF2BP; heat shock factor 2-binding protein\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"103068014 protein MMS22-like\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"103061058 TONSL; tonsoku-like protein\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"103064139 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"103062501 PARPBP; PCNA-interacting partner\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"112540321 CUNH17orf53; uncharacterized protein C17orf53 homolog isoform X1\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"103068233 MCM8; DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"103054389 DNA helicase MCM9-like\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"103057984 MCM9; DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"103064899 HNRNPUL1; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein U-like protein 1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"103058348 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2"
					},
					{
						"name":"103066870 MRNIP; MRN complex-interacting protein\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"103061970 CUNHXorf57; RPA-related protein RADX isoform X1\tK29002 RADX; RPA-related protein RADX"
					},
					{
						"name":"103048602 RBM6; RNA-binding protein 6 isoform X1\tK29038 RBM6; RNA-binding protein 6"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"103063490 XRCC6; X-ray repair cross-complementing protein 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"103050673 XRCC5; X-ray repair cross-complementing protein 5\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"103059879 DNA-dependent protein kinase catalytic subunit\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					},
					{
						"name":"103061618 DNA-dependent protein kinase catalytic subunit\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"103061835 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"103064733 DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"103050388 LIG4; DNA ligase 4\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"103057423 XRCC4; DNA repair protein XRCC4\tK10886 XRCC4; DNA-repair protein XRCC4"
					},
					{
						"name":"103055797 NHEJ1; non-homologous end-joining factor 1 isoform X2\tK10980 NHEJ1; non-homologous end-joining factor 1"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"103062692 POLL; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"103051733 POLM; DNA-directed DNA\/RNA polymerase mu isoform X1\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					},
					{
						"name":"103057405 DNTT; DNA nucleotidylexotransferase\tK00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]"
					},
					{
						"name":"103066680 POLB; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"103066205 APTX; aprataxin isoform X3\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"103055773 APLF; aprataxin and PNK-like factor\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"103056873 DCLRE1C; protein artemis isoform X1\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"103062604 TDP2; tyrosyl-DNA phosphodiesterase 2\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"103059470 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"103060396 structural maintenance of chromosomes flexible hinge domain-containing protein 1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"103054221 PWWP domain-containing protein MUM1-like isoform X3\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"112540503 PAXX; protein PAXX\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"103056937 CYREN; cell cycle regulator of non-homologous end joining\tK26155 CYREN; cell cycle regulator of non-homologous end joining"
					},
					{
						"name":"103050479 JMJD8; jmjC domain-containing protein 8\tK25792 JMJD8; jumonji domain-containing protein 8"
					},
					{
						"name":"112540253 SHLD1; uncharacterized protein C20orf196 homolog\tK26128 SHLD1; shieldin complex subunit 1"
					},
					{
						"name":"103059206 SHLD2; protein FAM35A\tK26129 SHLD2; shieldin complex subunit 2"
					},
					{
						"name":"103048857 BEND4; BEN domain-containing protein 4\tK27845 BEND4; BEN domain-containing protein 4"
					},
					{
						"name":"103051031 IFFO1; intermediate filament family orphan 1\tK28738 IFFO; non-homologous end joining factor IFFO"
					},
					{
						"name":"103068022 IFFO2; intermediate filament family orphan 2\tK28738 IFFO; non-homologous end joining factor IFFO"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"103067801 FANCA; Fanconi anemia group A protein\tK10888 FANCA; fanconi anemia group A protein"
					},
					{
						"name":"103050735 FANCB; Fanconi anemia group B protein\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"103058457 FANCC; Fanconi anemia group C protein isoform X1\tK10890 FANCC; fanconi anemia group C protein"
					},
					{
						"name":"103065828 FANCE; Fanconi anemia group E protein\tK10892 FANCE; fanconi anemia group E protein"
					},
					{
						"name":"103048146 Fanconi anemia group F protein-like\tK10893 FANCF; fanconi anemia group F protein"
					},
					{
						"name":"103068114 Fanconi anemia group F protein-like\tK10893 FANCF; fanconi anemia group F protein"
					},
					{
						"name":"103049768 FANCG; Fanconi anemia group G protein\tK10894 FANCG; fanconi anemia group G protein"
					},
					{
						"name":"103051811 FANCL; E3 ubiquitin-protein ligase FANCL\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"103066920 FAAP24; Fanconi anemia core complex-associated protein 24 isoform X1\tK10898 FAAP24; fanconi anemia-associated protein"
					},
					{
						"name":"103062499 FAAP100; Fanconi anemia core complex-associated protein 100 isoform X2\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"103049451 transcription factor HES-1\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"103056990 transcription factor HES-1-like\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"103055091 centromere protein S\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"103062298 CENPX; centromere protein X isoform X2\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"103064045 UBE2T; ubiquitin-conjugating enzyme E2 T isoform X1\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"103060640 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"103052651 TOP3B; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"103060611 TOP3A; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"103054812 RMI1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"103054875 RMI2; recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"103049962 FANCD2; Fanconi anemia group D2 protein\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"103062715 FANCI; LOW QUALITY PROTEIN: Fanconi anemia group I protein\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"103057262 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103068142 BRCA2; breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"103063956 BRIP1; Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"103057917 PALB2; partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"103067147 FAN1; fanconi-associated nuclease 1 isoform X1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"103051032 RAD51; DNA repair protein RAD51 homolog 1 isoform X1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"103066402 RAD51C; DNA repair protein RAD51 homolog 3\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"103055512 TELO2; telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"103053739 USP1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"103057288 WDR48; WD repeat-containing protein 48\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"103067969 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"103065562 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1 isoform X3\tK15499 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1"
					},
					{
						"name":"103051617 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2 isoform X9\tK15500 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2"
					},
					{
						"name":"103066361 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X2\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"103049158 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"103060775 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X4\tK15503 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B"
					},
					{
						"name":"103065303 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C isoform X1\tK15504 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"103058875 RNF8; E3 ubiquitin-protein ligase RNF8 isoform X1\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"103050073 RNF168; E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"103055331 RNF169; E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
					},
					{
						"name":"103060742 HERC2; E3 ubiquitin-protein ligase HERC2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					},
					{
						"name":"103061850 E3 ubiquitin-protein ligase HERC2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"103060460 WRAP53; telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"103064766 TPRN; taperin isoform X1\tK24164 TPRN; taperin"
					},
					{
						"name":"112542200 ZCWPW1; zinc finger CW-type PWWP domain protein 1\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"103053533 WDR70; WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"103060392 WDR76; WD repeat-containing protein 76 isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"103054468 HMCES; embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"103060980 POLH; DNA polymerase eta\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"103048544 POLI; DNA polymerase iota isoform X1\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"103053639 POLK; DNA polymerase kappa isoform X1\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"103052385 REV1; DNA repair protein REV1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"103061024 REV3L; DNA polymerase zeta catalytic subunit isoform X1\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"103060716 UBE2A; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"103050774 UBE2B; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"103056943 RAD18; E3 ubiquitin-protein ligase RAD18 isoform X1\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"103060562 HLTF; helicase-like transcription factor\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"103061382 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"103063088 UBE2V1; ubiquitin-conjugating enzyme E2 variant 1 isoform X4\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"103050238 UBE2N; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"103055444 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"103060695 PCLAF; PCNA-associated factor\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"103062501 PARPBP; PCNA-interacting partner\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"103049959 SPRTN; sprT-like domain-containing protein Spartan\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"103064464 GCNA; acidic repeat-containing protein isoform X1\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"103057650 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"103057083 RAD9B; cell cycle checkpoint control protein RAD9B\tK10995 RAD9B; cell cycle checkpoint control protein RAD9B"
				},
				{
					"name":"103053658 HUS1; checkpoint protein HUS1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"103059899 RAD1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"103052608 RAD17; LOW QUALITY PROTEIN: cell cycle checkpoint protein RAD17\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"103054137 RFC4; replication factor C subunit 4 isoform X2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"103055645 RFC2; replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"103050610 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"103050675 RFC3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"103059899 RAD1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"103059942 TIMELESS; protein timeless homolog isoform X1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"103050276 TIPIN; TIMELESS-interacting protein isoform X2\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"103050315 CLSPN; claspin\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"103055512 TELO2; telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"103066466 TTI1; TELO2-interacting protein 1 homolog\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"103062224 TTI2; TELO2-interacting protein 2\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"103054836 large proline-rich protein BAG6-like\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"103061053 BAG6; large proline-rich protein BAG6\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"103060293 UBL4A; ubiquitin-like protein 4A\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"103057614 GET4; Golgi to ER traffic protein 4 homolog\tK23387 GET4; Golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"103049761 integrator complex subunit 3\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"103061553 NABP1; SOSS complex subunit B2\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"103063715 NABP2; SOSS complex subunit B1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"103063096 INIP; SOSS complex subunit C isoform X2\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"103067932 serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"103049942 ATRIP; ATR-interacting protein\tK10905 ATRIP; ATR interacting protein"
				},
				{
					"name":"103059474 ETAA1; ewing's tumor-associated antigen 1\tK28856 ETAA1; Ewing's tumor-associated antigen 1"
				},
				{
					"name":"103049413 ATM; serine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"103061365 TP53; cellular tumor antigen p53\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"112542108 cellular tumor antigen p53-like\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"103064116 CHEK1; serine\/threonine-protein kinase Chk1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"103066019 CHEK2; serine\/threonine-protein kinase Chk2\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"103059140 CDC25A; M-phase inducer phosphatase 1 isoform X1\tK06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]"
				},
				{
					"name":"103054614 CDC25B; M-phase inducer phosphatase 2\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"103051692 CDC25C; M-phase inducer phosphatase 3\tK05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]"
				},
				{
					"name":"103048257 YWHAZ; 14-3-3 protein zeta\/delta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"103055521 YWHAB; 14-3-3 protein beta\/alpha\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"103059524 YWHAQ; 14-3-3 protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"103055823 YWHAG; 14-3-3 protein gamma\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"103065741 14-3-3 protein gamma-like\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"103064385 YWHAE; 14-3-3 protein epsilon isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"103054315 NAV2; neuron navigator 2 isoform X3\tK19483 NAV2; neuron navigator 2 [EC:5.6.2.4]"
				},
				{
					"name":"103052681 WEE1; wee1-like protein kinase isoform X2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"103055243 WEE2; wee1-like protein kinase 2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"103050831 PER1; period circadian protein homolog 1\tK21944 PER1; period circadian protein 1"
				},
				{
					"name":"103048182 PER2; period circadian protein homolog 2\tK02633 PER2; period circadian protein 2"
				},
				{
					"name":"103055986 PER3; LOW QUALITY PROTEIN: period circadian protein homolog 3\tK21945 PER3; period circadian protein 3"
				},
				{
					"name":"103050020 MDC1; mediator of DNA damage checkpoint protein 1 isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"103060763 PLS3; plastin-3\tK17336 PLS3; plastin-3"
				},
				{
					"name":"103066745 AEN; apoptosis-enhancing nuclease\tK18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]"
				},
				{
					"name":"103065204 PLK3; serine\/threonine-protein kinase PLK3\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
				},
				{
					"name":"103050987 inactive serine\/threonine-protein kinase PLK5-like isoform X2\tK19596 PLK5; inactive serine\/threonine-protein kinase PLK5"
				},
				{
					"name":"103055048 NEK1; serine\/threonine-protein kinase Nek1 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"103062506 serine\/threonine-protein kinase Nek4-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"103063229 NEK5; serine\/threonine-protein kinase Nek5 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"103060710 NEK10; serine\/threonine-protein kinase Nek10\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"103061526 NEK11; serine\/threonine-protein kinase Nek11\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"103067771 DONSON; protein downstream neighbor of Son isoform X1\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"103059486 KANK1; KN motif and ankyrin repeat domain-containing protein 1 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103060880 KANK4; KN motif and ankyrin repeat domain-containing protein 4\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103061294 KANK2; KN motif and ankyrin repeat domain-containing protein 2 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103063685 KN motif and ankyrin repeat domain-containing protein 3-like\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103050871 CHMP4C; charged multivesicular body protein 4c\tK24782 CHMP4C; charged multivesicular body protein 4C"
				},
				{
					"name":"103053086 vacuolar protein sorting-associated protein 4B\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"103056985 VPS4A; vacuolar protein sorting-associated protein 4A\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"103052364 ZFYVE19; abscission\/NoCut checkpoint regulator\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"103065338 SDE2; replication stress response regulator SDE2\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"103048784 BLCAP; bladder cancer-associated protein\tK29062 BLCAP; apoptosis inducing factor BLCAP"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"103048988 POLQ; DNA polymerase theta\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"103057244 MYBBP1A; myb-binding protein 1A\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"103049953 PRIMPOL; DNA-directed primase\/polymerase protein isoform X1\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"103050274 TREX2; three prime repair exonuclease 2 isoform X2\tK10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]"
				},
				{
					"name":"103059041 DCLRE1A; DNA cross-link repair 1A protein isoform X1\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"103066211 DCLRE1B; 5' exonuclease Apollo isoform X2\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"103065583 EXO5; exonuclease V\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"103067719 ENDOV; endonuclease V isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"103062294 ZRANB3; DNA annealing helicase and endonuclease ZRANB3\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"103053641 ANKLE1; ankyrin repeat and LEM domain-containing protein 1\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"103050488 HELQ; helicase POLQ-like\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				},
				{
					"name":"103058225 DNA excision repair protein ERCC-6-like 2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				},
				{
					"name":"103066081 DNA excision repair protein ERCC-6-like 2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"103065320 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"103064862 CDC5L; cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"103065236 BCAS2; pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"103053093 PLRG1; pleiotropic regulator 1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"103061592 NUDT15; nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"103052574 NUDT1; 7,8-dihydro-8-oxoguanine triphosphatase\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"103062314 NUDT18; 8-oxo-dGDP phosphatase NUDT18\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"103059767 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X3\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"103055237 RRM1; ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"103049984 RRM2; ribonucleoside-diphosphate reductase subunit M2 isoform X1\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"103062671 ribonucleoside-diphosphate reductase subunit M2 B-like isoform X1\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"103054500 MGMT; methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"103067349 deoxyribodipyrimidine photo-lyase-like\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"103057544 UNG; uracil-DNA glycosylase isoform X1\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"103060135 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"103052134 MPG; DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"103061782 MUTYH; adenine DNA glycosylase isoform X3\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"103048346 NTHL1; endonuclease III-like protein 1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"103055480 SSBP1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"103055480 SSBP1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"103061592 NUDT15; nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"103059767 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X3\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}