{
	"name":"hsa03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"8731 RNMT; mRNA cap guanine-N(7) methyltransferase isoform 2\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"8732 RNGTT; mRNA-capping enzyme isoform a\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]"
					},
					{
						"name":"1022 CDK7; cyclin-dependent kinase 7 isoform 1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"23070 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]"
					},
					{
						"name":"55783 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]"
					},
					{
						"name":"353267 RAMACL; RNA guanine-N7 methyltransferase-activating subunit-like protein\tK18708 FAM103A1; RNMT-activating mini protein"
					},
					{
						"name":"83640 RAMAC; RNA guanine-N7 methyltransferase activating subunit\tK18708 FAM103A1; RNMT-activating mini protein"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"4686 NCBP1; nuclear cap-binding protein subunit 1 isoform 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"22916 NCBP2; nuclear cap-binding protein subunit 2 isoform 1\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					},
					{
						"name":"392517 NCBP2L; nuclear cap-binding protein subunit 2-like\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"11051 NUDT21; cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					},
					{
						"name":"11052 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform 1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					},
					{
						"name":"79869 CPSF7; cleavage and polyadenylation specificity factor subunit 7 isoform 2\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"10978 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 isoform 1\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"51585 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform 3\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"29894 CPSF1; cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"53981 CPSF2; cleavage and polyadenylation specificity factor subunit 2 isoform 1\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"51692 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform a\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"10898 CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform 1\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"642843 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"81608 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform 1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"55339 WDR33; pre-mRNA 3' end processing protein WDR33 isoform 1\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"80335 WDR82; WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"5499 PPP1CA; serine\/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"5500 PPP1CB; serine\/threonine-protein phosphatase PP1-beta catalytic subunit isoform 1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"5501 PPP1CC; serine\/threonine-protein phosphatase PP1-gamma catalytic subunit isoform 1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"136157 SSU72L6; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 6\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"143506 SSU72L3; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 3\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"196120 SSU72L5; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 5\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"29101 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"390031 SSU72L2; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 2\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"390033 SSU72L1; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 1\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"441584 SSU72L4; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 4\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"1477 CSTF1; cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1"
					},
					{
						"name":"1478 CSTF2; cleavage stimulation factor subunit 2 isoform 2\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"23283 CSTF2T; cleavage stimulation factor subunit 2 tau variant\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"1479 CSTF3; cleavage stimulation factor subunit 3 isoform 1\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"8189 SYMPK; symplekin\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"6628 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform B'\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"6634 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"6635 SNRPE; small nuclear ribonucleoprotein E isoform 1\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"6636 SNRPF; small nuclear ribonucleoprotein F isoform 1\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"6637 SNRPG; small nuclear ribonucleoprotein G isoform a\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"84967 LSM10; U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10"
					},
					{
						"name":"134353 LSM11; U7 snRNA-associated Sm-like protein LSm11\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11"
					},
					{
						"name":"53981 CPSF2; cleavage and polyadenylation specificity factor subunit 2 isoform 1\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"51692 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform a\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"1478 CSTF2; cleavage stimulation factor subunit 2 isoform 2\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"23283 CSTF2T; cleavage stimulation factor subunit 2 tau variant\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"8189 SYMPK; symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"7884 SLBP; histone RNA hairpin-binding protein isoform 1\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"9994 CASP8AP2; CASP8-associated protein 2\tK25593 CASP8AP2; CASP8-associated protein 2"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"6827 SUPT4H1; transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"6829 SUPT5H; transcription elongation factor SPT5 isoform a\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"56339 METTL3; N(6)-adenosine-methyltransferase catalytic subunit METTL3\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]"
					},
					{
						"name":"57721 METTL14; N(6)-adenosine-methyltransferase non-catalytic subunit METTL14\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"64863 METTL4; N(6)-adenine-specific methyltransferase METTL4 isoform 1\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]"
					},
					{
						"name":"79066 METTL16; RNA N(6)-adenosine-methyltransferase METTL16\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"9589 WTAP; pre-mRNA-splicing regulator WTAP isoform 1\tK22824 WTAP; pre-mRNA-splicing regulator WTAP"
					},
					{
						"name":"25962 VIRMA; protein virilizer homolog isoform 1\tK22910 VIRMA; protein virilizer"
					},
					{
						"name":"29890 RBM15B; putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"64783 RBM15; RNA-binding protein 15 isoform 1\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"23091 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform 2\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"79872 CBLL1; E3 ubiquitin-protein ligase Hakai isoform 1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"10914 PAPOLA; poly(A) polymerase alpha isoform 1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"56903 PAPOLB; poly(A) polymerase beta\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"64895 PAPOLG; poly(A) polymerase gamma\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"167153 TENT2; poly(A) RNA polymerase GLD2 isoform 1\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]"
					},
					{
						"name":"64852 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase isoform 1\tK18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"580 BARD1; BRCA1-associated RING domain protein 1 isoform 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"64062 RBM26; RNA-binding protein 26 isoform 4\tK13192 RBM26; RNA-binding protein 26"
					},
					{
						"name":"79068 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform 3\tK19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"54890 ALKBH5; RNA demethylase ALKBH5\tK10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"23435 TARDBP; TAR DNA-binding protein 43\tK23600 TARDBP; TAR DNA-binding protein 43"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"79665 DHX40; probable ATP-dependent RNA helicase DHX40 isoform 1\tK18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]"
				},
				{
					"name":"22944 KIN; DNA\/RNA-binding protein KIN17\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"79828 METTL8; tRNA N(3)-cytidine methyltransferase METTL8, mitochondrial isoform 5\tK24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]"
				},
				{
					"name":"79091 METTL22; methyltransferase-like protein 22\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]"
				},
				{
					"name":"115572 TENT5B; terminal nucleotidyltransferase 5B\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"55603 TENT5A; terminal nucleotidyltransferase 5A\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"54855 TENT5C; terminal nucleotidyltransferase 5C\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]"
				},
				{
					"name":"169966 TENT5D; terminal nucleotidyltransferase 5D\tK23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]"
				},
				{
					"name":"79882 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform 1\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14"
				},
				{
					"name":"51593 SRRT; serrate RNA effector molecule homolog isoform a\tK27103 SRRT; serrate RNA effector molecule"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"9939 RBM8A; RNA-binding protein 8A\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"4116 MAGOH; protein mago nashi homolog\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"55110 MAGOHB; protein mago nashi homolog 2 isoform 1\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"10189 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"7919 DDX39B; spliceosome RNA helicase DDX39B\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"9775 EIF4A3; eukaryotic initiation factor 4A-III isoform 1\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"51244 CCDC174; coiled-coil domain-containing protein 174 isoform a\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"22794 CASC3; protein CASC3\tK14323 CASC3; protein CASC3"
					},
					{
						"name":"10284 SAP18; histone deacetylase complex subunit SAP18 isoform 1\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"5411 PNN; pinin\tK13114 PNN; pinin"
					},
					{
						"name":"22985 ACIN1; apoptotic chromatin condensation inducer in the nucleus isoform 1\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus"
					},
					{
						"name":"10921 RNPS1; RNA-binding protein with serine-rich domain 1 isoform a\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"10250 SRRM1; serine\/arginine repetitive matrix protein 1 isoform 2\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"9984 THOC1; THO complex subunit 1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"57187 THOC2; THO complex subunit 2 isoform 1\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"84321 THOC3; THO complex subunit 3 isoform 1\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"10189 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"8563 THOC5; THO complex subunit 5\tK13174 THOC5; THO complex subunit 5"
					},
					{
						"name":"79228 THOC6; THO complex subunit 6 isoform 1\tK13175 THOC6; THO complex subunit 6"
					},
					{
						"name":"80145 THOC7; THO complex subunit 7 isoform 1\tK13176 THOC7; THO complex subunit 7"
					},
					{
						"name":"26097 CHTOP; chromatin target of PRMT1 protein isoform 1\tK28424 CHTOP; chromatin target of PRMT1 protein"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"55795 PCID2; PCI domain-containing protein 2 isoform 1\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"7979 SEM1; 26S proteasome complex subunit SEM1 isoform c\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"56943 ENY2; transcription and mRNA export factor ENY2 isoform 1\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"1069 CETN2; centrin-2\tK10840 CETN2; centrin-2"
					},
					{
						"name":"1070 CETN3; centrin-3 isoform 2\tK16466 CETN3; centrin-3"
					},
					{
						"name":"8888 MCM3AP; germinal-center associated nuclear protein\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"7175 TPR; nucleoprotein TPR\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"8480 RAE1; mRNA export factor RAE1\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"6396 SEC13; protein SEC13 homolog isoform 1\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"79023 NUP37; nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37"
					},
					{
						"name":"79902 NUP85; nuclear pore complex protein Nup85 isoform 1\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"348995 NUP43; nucleoporin Nup43\tK14305 NUP43; nuclear pore complex protein Nup43"
					},
					{
						"name":"10762 NUP50; nuclear pore complex protein Nup50 isoform b\tK14295 NUP50; nuclear pore complex protein Nup50"
					},
					{
						"name":"53371 NUP54; nucleoporin p54 isoform 1\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"23636 NUP62; nuclear pore glycoprotein p62\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"4927 NUP88; nuclear pore complex protein Nup88 isoform 2\tK14318 NUP88; nuclear pore complex protein Nup88"
					},
					{
						"name":"9688 NUP93; nuclear pore complex protein Nup93 isoform 1\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"4928 NUP98; nuclear pore complex protein Nup98-Nup96 isoform 6 precursor\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"57122 NUP107; nuclear pore complex protein Nup107 isoform 1\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"55746 NUP133; nuclear pore complex protein Nup133\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"23511 NUP188; nucleoporin NUP188\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"9972 NUP153; nuclear pore complex protein Nup153 isoform 2\tK14296 NUP153; nuclear pore complex protein Nup153"
					},
					{
						"name":"9631 NUP155; nuclear pore complex protein Nup155 isoform 1\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"23279 NUP160; nuclear pore complex protein Nup160 isoform 1\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"129401 NUP35; nucleoporin NUP35 isoform a\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"23165 NUP205; nuclear pore complex protein Nup205 isoform 1\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"23225 NUP210; nuclear pore membrane glycoprotein 210 precursor\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"91181 NUP210L; nuclear pore membrane glycoprotein 210-like isoform 1 precursor\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"8021 NUP214; nuclear pore complex protein Nup214 isoform 2\tK14317 NUP214; nuclear pore complex protein Nup214"
					},
					{
						"name":"100101267 POM121C; nuclear envelope pore membrane protein POM 121C\tK14316 POM121; nuclear pore complex protein Nup121"
					},
					{
						"name":"94026 POM121L2; POM121-like protein 2\tK14316 POM121; nuclear pore complex protein Nup121"
					},
					{
						"name":"9883 POM121; nuclear envelope pore membrane protein POM 121 isoform 4\tK14316 POM121; nuclear pore complex protein Nup121"
					},
					{
						"name":"9818 NUP58; nucleoporin p58\/p45 isoform a\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"11097 NUP42; nucleoporin NUP42 isoform 2\tK14321 NUPL2; nucleoporin-like protein 2"
					},
					{
						"name":"55706 NDC1; nucleoporin NDC1 isoform 1\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"81929 SEH1L; nucleoporin SEH1 isoform 2\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"5903 RANBP2; E3 SUMO-protein ligase RanBP2 isoform 1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
					},
					{
						"name":"59343 SENP2; sentrin-specific protease 2\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
					},
					{
						"name":"8086 AAAS; aladin isoform 1\tK14320 AAAS; aladin"
					},
					{
						"name":"1070 CETN3; centrin-3 isoform 2\tK16466 CETN3; centrin-3"
					},
					{
						"name":"2733 GLE1; mRNA export factor GLE1 isoform 1\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"10482 NXF1; nuclear RNA export factor 1 isoform 1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"56000 NXF3; nuclear RNA export factor 3\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"56001 NXF2; nuclear RNA export factor 2\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"728343 NXF2B; nuclear RNA export factor 2\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"29107 NXT1; NTF2-related export protein 1\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					},
					{
						"name":"55916 NXT2; NTF2-related export protein 2 isoform 2\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					},
					{
						"name":"23742 NPAP1; nuclear pore-associated protein 1\tK26564 NPAP1; nuclear pore-associated protein 1"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"5901 RAN; GTP-binding nuclear protein Ran isoform 1\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"23519 ANP32D; acidic leucine-rich nuclear phosphoprotein 32 family member D\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D"
					},
					{
						"name":"8125 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D"
					},
					{
						"name":"10541 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B"
					},
					{
						"name":"8741 TNFSF13; tumor necrosis factor ligand superfamily member 13 isoform alpha precursor\tK05475 TNFSF13; tumor necrosis factor ligand superfamily member 13"
					},
					{
						"name":"1994 ELAVL1; ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"1993 ELAVL2; ELAV-like protein 2 isoform a\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"1995 ELAVL3; ELAV-like protein 3 isoform 1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"1996 ELAVL4; ELAV-like protein 4 isoform 9\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"23197 FAF2; FAS-associated factor 2\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"7415 VCP; transitional endoplasmic reticulum ATPase isoform 1\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"79609 VCPKMT; protein N-lysine methyltransferase METTL21D isoform a\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]"
					},
					{
						"name":"30000 TNPO2; transportin-2 isoform 1\tK18727 TNPO2; transportin-2"
					},
					{
						"name":"7514 XPO1; exportin-1 isoform 1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"23039 XPO7; exportin-7 isoform b\tK18460 XPO7; exportin-7"
					},
					{
						"name":"64901 RANBP17; ran-binding protein 17\tK24115 RANBP17; Ran-binding protein 17"
					},
					{
						"name":"5905 RANGAP1; ran GTPase-activating protein 1\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"8148 TAF15; TATA-binding protein-associated factor 2N isoform 1\tK14651 TAF15; transcription initiation factor TFIID subunit 15"
					},
					{
						"name":"10204 NUTF2; nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					},
					{
						"name":"128322 NUTF2P4; nuclear transport factor 2-like\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"1977 EIF4E; eukaryotic translation initiation factor 4E isoform 1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"253314 EIF4E1B; eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"9470 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform A\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"1973 EIF4A1; eukaryotic initiation factor 4A-I isoform 1\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"1974 EIF4A2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"1981 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform 5\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"1982 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform 1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"8672 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform 3\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"1975 EIF4B; eukaryotic translation initiation factor 4B isoform 2\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"7458 EIF4H; eukaryotic translation initiation factor 4H isoform 1\tK24086 EIF4H; translation initiation factor 4H"
					},
					{
						"name":"1978 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1"
					},
					{
						"name":"1979 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2"
					},
					{
						"name":"8637 EIF4EBP3; eukaryotic translation initiation factor 4E-binding protein 3\tK18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3"
					},
					{
						"name":"56478 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform a\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"23357 ANGEL1; protein angel homolog 1 isoform 4\tK18729 ANGEL; protein angel"
					},
					{
						"name":"90806 ANGEL2; protein angel homolog 2 isoform a\tK18729 ANGEL; protein angel"
					},
					{
						"name":"2332 FMR1; fragile X messenger ribonucleoprotein 1 isoform ISO1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"8087 FXR1; RNA-binding protein FXR1 isoform a\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"9513 FXR2; RNA-binding protein FXR2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"23191 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform a\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"26999 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform c\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"25929 GEMIN5; gem-associated protein 5 isoform 1\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"10460 TACC3; transforming acidic coiled-coil-containing protein 3 isoform 1\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"132864 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform C\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"22849 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform 1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"64506 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"80315 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform a\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"1654 DDX3X; ATP-dependent RNA helicase DDX3X isoform 1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"26058 GIGYF2; GRB10-interacting GYF protein 2 isoform b\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"64599 GIGYF1; GRB10-interacting GYF protein 1 isoform b\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"132430 PABPC4L; polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"140886 PABPC5; polyadenylate-binding protein 5\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"26986 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"340529 PABPC1L2A; polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"5042 PABPC3; polyadenylate-binding protein 3\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"645974 PABPC1L2B; polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"80336 PABPC1L; polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"8761 PABPC4; polyadenylate-binding protein 4 isoform 2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"10605 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform 1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1"
					},
					{
						"name":"400961 PAIP2B; polyadenylate-binding protein-interacting protein 2B\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"51247 PAIP2; polyadenylate-binding protein-interacting protein 2\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"6499 SKIC2; superkiller complex protein 2\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"10522 DEAF1; deformed epidermal autoregulatory factor 1 homolog isoform a\tK23041 DEAF1; deformed epidermal autoregulatory factor 1"
					},
					{
						"name":"100101490 MCTS2; malignant T-cell-amplified sequence 2\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"28985 MCTS1; malignant T-cell-amplified sequence 1 isoform 1\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"8562 DENR; density-regulated protein\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex",
					"children":[
					{
						"name":"339 APOBEC1; C->U-editing enzyme APOBEC-1 isoform a\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"29974 A1CF; APOBEC1 complementation factor isoform 2\tK24978 A1CF; APOBEC1 complementation factor"
					}
					]
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"84305 PYM1; partner of Y14 and mago isoform 1\tK14294 WIBG; partner of Y14 and mago"
					},
					{
						"name":"144983 HNRNPA1L2; heterogeneous nuclear ribonucleoprotein A1-like 2\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"220988 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform a\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"3178 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform b\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"642659 HNRNPA1L3; heterogeneous nuclear ribonucleoprotein A1-like 3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"124540 MSI2; RNA-binding protein Musashi homolog 2 isoform a\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"26528 DAZAP1; DAZ-associated protein 1 isoform b\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"4440 MSI1; RNA-binding protein Musashi homolog 1 isoform a\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"10767 HBS1L; HBS1-like protein isoform 1\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"53918 PELO; protein pelota homolog\tK06965 PELO; protein pelota"
					},
					{
						"name":"100529063 BCL2L2-PABPN1; BCL2L2-PABPN1 protein isoform 4\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"390748 PABPN1L; embryonic polyadenylate-binding protein 2 isoform 1\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"8106 PABPN1; polyadenylate-binding protein 2 isoform 1\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"11269 DDX19B; ATP-dependent RNA helicase DDX19B isoform 1\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"55308 DDX19A; ATP-dependent RNA helicase DDX19A isoform 1\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"29118 DDX25; ATP-dependent RNA helicase DDX25 isoform 1\tK18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]"
					},
					{
						"name":"56949 XAB2; pre-mRNA-splicing factor SYF1\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"84324 SARNP; SAP domain-containing ribonucleoprotein\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"1104 RCC1; regulator of chromosome condensation isoform c\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"55323 LARP6; la-related protein 6 isoform 1\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"5813 PURA; transcriptional activator protein Pur-alpha\tK21772 PURA; transcriptional activator protein Pur-alpha"
					},
					{
						"name":"5814 PURB; transcriptional regulator protein Pur-beta\tK21799 PURB; transcriptional activator protein Pur-beta"
					},
					{
						"name":"84271 POLDIP3; polymerase delta-interacting protein 3 isoform 1\tK22414 POLDIP3; polymerase delta-interacting protein 3"
					},
					{
						"name":"441155 ZC3H11C; zinc finger CCCH domain-containing protein 11C\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"643136 ZC3H11B; zinc finger CCCH domain-containing protein 11B\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"9877 ZC3H11A; zinc finger CCCH domain-containing protein 11A isoform 1\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"114823 LENG8; leukocyte receptor cluster member 8 isoform 6\tK23802 LENG8; SAC3 family protein LENG8\/THP3"
					},
					{
						"name":"197135 PATL2; protein PAT1 homolog 2 isoform 1\tK24823 PATL2; protein PAT1 homolog 2"
					},
					{
						"name":"84248 FYTTD1; UAP56-interacting factor isoform 1\tK28772 FYTTD1; UAP56-interacting factor"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"2107 ETF1; eukaryotic peptide chain release factor subunit 1 isoform 1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"23708 GSPT2; eukaryotic peptide chain release factor GTP-binding subunit ERF3B\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"2935 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 3\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"5976 UPF1; regulator of nonsense transcripts 1 isoform 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"26019 UPF2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"65109 UPF3B; regulator of nonsense transcripts 3B isoform 1\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"65110 UPF3A; regulator of nonsense transcripts 3A isoform hUpf3p\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"5515 PPP2CA; serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform 1\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"5516 PPP2CB; serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"5518 PPP2R1A; serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform 1\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"5519 PPP2R1B; serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform a\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"5520 PPP2R2A; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform 1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"5521 PPP2R2B; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform e\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"5522 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform a\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"55844 PPP2R2D; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform a\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"28227 PPP2R3B; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"55012 PPP2R3C; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform 1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"5523 PPP2R3A; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform 1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"5525 PPP2R5A; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform 1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"5526 PPP2R5B; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"5527 PPP2R5C; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform a\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"5528 PPP2R5D; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform 1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"5529 PPP2R5E; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform a\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"23049 SMG1; serine\/threonine-protein kinase SMG1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"23381 SMG5; nonsense-mediated mRNA decay factor SMG5 isoform 1\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"23293 SMG6; telomerase-binding protein EST1A isoform 1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"9887 SMG7; nonsense-mediated mRNA decay factor SMG7 isoform 1\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"55181 SMG8; nonsense-mediated mRNA decay factor SMG8\tK18734 SMG8; protein SMG8"
					},
					{
						"name":"56006 SMG9; nonsense-mediated mRNA decay factor SMG9\tK18735 SMG9; protein SMG9"
					},
					{
						"name":"26058 GIGYF2; GRB10-interacting GYF protein 2 isoform b\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"64599 GIGYF1; GRB10-interacting GYF protein 1 isoform b\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"79048 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform 1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"9728 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform 1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"9704 DHX34; probable ATP-dependent RNA helicase DHX34\tK20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]"
					},
					{
						"name":"9567 GTPBP1; GTP-binding protein 1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"9933 PUM3; pumilio homolog 3\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"4644 MYO5A; unconventional myosin-Va isoform 1\tK10357 MYO5; myosin V"
					},
					{
						"name":"4645 MYO5B; unconventional myosin-Vb\tK10357 MYO5; myosin V"
					},
					{
						"name":"55930 MYO5C; unconventional myosin-Vc\tK10357 MYO5; myosin V"
					},
					{
						"name":"23299 BICD2; protein bicaudal D homolog 2 isoform 2\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"636 BICD1; protein bicaudal D homolog 1 isoform 1\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"161829 EXD1; piRNA biogenesis protein EXD1 isoform 2\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals",
					"children":[
					{
						"name":"60 ACTB; actin, cytoplasmic 1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"71 ACTG1; actin, cytoplasmic 2\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"4155 MBP; Golli-MBP isoform 1\tK17269 MBP; myelin basic protein"
					},
					{
						"name":"7431 VIM; vimentin\tK07606 VIM; vimentin"
					},
					{
						"name":"107984936 metallothionein-1E-like\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4489 MT1A; metallothionein-1A\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4490 MT1B; metallothionein-1B\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4493 MT1E; metallothionein-1E isoform 2\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4494 MT1F; metallothionein-1F isoform 1\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4495 MT1G; metallothionein-1G isoform 2\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4496 MT1H; metallothionein-1H\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4499 MT1M; metallothionein-1M\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4501 MT1X; metallothionein-1X\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4502 MT2A; metallothionein-2\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"645745 MT1HL1; metallothionein 1H-like protein 1\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"4609 MYC; myc proto-oncogene protein isoform 1\tK04377 MYC; Myc proto-oncogene protein"
					},
					{
						"name":"2657 GDF1; embryonic growth\/differentiation factor 1 precursor\tK05495 GDF1; growth differentiation factor 1"
					},
					{
						"name":"6911 TBX6; T-box transcription factor TBX6\tK10180 TBX6; T-box protein 6"
					},
					{
						"name":"340719 NANOS1; nanos homolog 1\tK18741 NANOS1; protein nanos 1"
					}
					]
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"81030 ZBP1; Z-DNA-binding protein 1 isoform a\tK12965 ZBP1; Z-DNA binding protein 1"
					},
					{
						"name":"8570 KHSRP; far upstream element-binding protein 2 isoform 1\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"8880 FUBP1; far upstream element-binding protein 1 isoform 2\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"8939 FUBP3; far upstream element-binding protein 3\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"1915 EEF1A1; elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"1917 EEF1A2; elongation factor 1-alpha 2\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"1937 EEF1G; elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"3181 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2\/B1 isoform B1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1"
					},
					{
						"name":"10456 HAX1; HCLS1-associated protein X-1 isoform a\tK16220 HAX1; HCLS1-associated protein X-1"
					},
					{
						"name":"3267 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform 2\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1"
					},
					{
						"name":"27067 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform a\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"6780 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform b\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"10643 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3\tK13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3"
					},
					{
						"name":"5725 PTBP1; polypyrimidine tract-binding protein 1 isoform a\tK13218 PTBP1; polypyrimidine tract-binding protein 1"
					},
					{
						"name":"132864 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform C\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"22849 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform 1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"64506 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"80315 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform a\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"2332 FMR1; fragile X messenger ribonucleoprotein 1 isoform ISO1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"8087 FXR1; RNA-binding protein FXR1 isoform a\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"9513 FXR2; RNA-binding protein FXR2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"23191 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform a\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"26999 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform c\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"5094 PCBP2; poly(rC)-binding protein 2 isoform d\tK13162 PCBP2; poly(rC)-binding protein 2"
					},
					{
						"name":"54039 PCBP3; poly(rC)-binding protein 3 isoform 1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"57060 PCBP4; poly(rC)-binding protein 4 isoform c\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"4076 CAPRIN1; caprin-1 isoform 1\tK18743 CAPRIN1; caprin-1"
					},
					{
						"name":"65981 CAPRIN2; caprin-2 isoform 1\tK18744 CAPRIN2; caprin-2"
					},
					{
						"name":"4904 YBX1; Y-box-binding protein 1\tK09276 YBX1; Y-box-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"54464 XRN1; 5'-3' exoribonuclease 1 isoform a\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"192669 AGO3; protein argonaute-3 isoform a\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"192670 AGO4; protein argonaute-4\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"26523 AGO1; protein argonaute-1 isoform 1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"27161 AGO2; protein argonaute-2 isoform 1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"1977 EIF4E; eukaryotic translation initiation factor 4E isoform 1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"253314 EIF4E1B; eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"9470 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform A\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"5976 UPF1; regulator of nonsense transcripts 1 isoform 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"1654 DDX3X; ATP-dependent RNA helicase DDX3X isoform 1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"8653 DDX3Y; ATP-dependent RNA helicase DDX3Y isoform 1\tK17642 DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:5.6.2.7]"
					},
					{
						"name":"1656 DDX6; probable ATP-dependent RNA helicase DDX6 isoform 1\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"399664 MEX3D; RNA-binding protein MEX3D isoform 1\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"51320 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"84206 MEX3B; RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"92312 MEX3A; RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"10922 FASTK; fas-activated serine\/threonine kinase isoform 1\tK08290 FASTK; Fas-activated serine\/threonine kinase [EC:2.7.11.8]"
					},
					{
						"name":"149986 LSM14B; protein LSM14 homolog B\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"26065 LSM14A; protein LSM14 homolog A isoform a\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"5093 PCBP1; poly(rC)-binding protein 1\tK12889 PCBP1; poly(rC)-binding protein 1"
					},
					{
						"name":"5094 PCBP2; poly(rC)-binding protein 2 isoform d\tK13162 PCBP2; poly(rC)-binding protein 2"
					},
					{
						"name":"4904 YBX1; Y-box-binding protein 1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"126374 WTIP; Wilms tumor protein 1-interacting protein\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"84962 AJUBA; LIM domain-containing protein ajuba isoform 1\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"8994 LIMD1; LIM domain-containing protein 1\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"339 APOBEC1; C->U-editing enzyme APOBEC-1 isoform a\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"100913187 APOBEC3A_B; probable DNA dC->dU-editing enzyme APOBEC-3A\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"140564 APOBEC3D; DNA dC->dU-editing enzyme APOBEC-3D isoform 1\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"164668 APOBEC3H; DNA dC->dU-editing enzyme APOBEC-3H isoform SV-200\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"200315 APOBEC3A; DNA dC->dU-editing enzyme APOBEC-3A isoform a\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"200316 APOBEC3F; DNA dC->dU-editing enzyme APOBEC-3F isoform a\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"27350 APOBEC3C; DNA dC->dU-editing enzyme APOBEC-3C\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"60489 APOBEC3G; DNA dC->dU-editing enzyme APOBEC-3G isoform 1\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"9582 APOBEC3B; DNA dC->dU-editing enzyme APOBEC-3B isoform a\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]"
					},
					{
						"name":"4343 MOV10; helicase MOV-10 isoform 1\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"55629 PNRC2; proline-rich nuclear receptor coactivator 2\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2"
					},
					{
						"name":"3842 TNPO1; transportin-1 isoform 1\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"23049 SMG1; serine\/threonine-protein kinase SMG1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"23381 SMG5; nonsense-mediated mRNA decay factor SMG5 isoform 1\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"23293 SMG6; telomerase-binding protein EST1A isoform 1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"9887 SMG7; nonsense-mediated mRNA decay factor SMG7 isoform 1\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"7538 ZFP36; mRNA decay activator protein ZFP36\tK15308 TTP; tristetraprolin"
					},
					{
						"name":"677 ZFP36L1; mRNA decay activator protein ZFP36L1 isoform 1\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"678 ZFP36L2; mRNA decay activator protein ZFP36L2\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"389421 LIN28B; protein lin-28 homolog B isoform 1\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"79727 LIN28A; protein lin-28 homolog A\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"3064 HTT; huntingtin isoform 1\tK04533 HD; huntingtin"
					},
					{
						"name":"10526 IPO8; importin-8 isoform 1\tK18755 IPO8; importin-8"
					},
					{
						"name":"80114 BICC1; protein bicaudal C homolog 1\tK18756 BICC1; protein bicaudal C"
					},
					{
						"name":"144983 HNRNPA1L2; heterogeneous nuclear ribonucleoprotein A1-like 2\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"220988 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform a\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"3178 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform b\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"642659 HNRNPA1L3; heterogeneous nuclear ribonucleoprotein A1-like 3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"5566 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"5567 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform 2\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"5568 PRKACG; cAMP-dependent protein kinase catalytic subunit gamma\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"23367 LARP1; la-related protein 1 isoform 2\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"55132 LARP1B; la-related protein 1B isoform 1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"11273 ATXN2L; ataxin-2-like protein isoform 1\tK23625 ATXN2; ataxin-2"
					},
					{
						"name":"6311 ATXN2; ataxin-2 isoform 1\tK23625 ATXN2; ataxin-2"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"167227 DCP2; m7GpppN-mRNA hydrolase isoform 1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"55802 DCP1A; mRNA-decapping enzyme 1A isoform a\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"196513 DCP1B; mRNA-decapping enzyme 1B isoform 1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"27257 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"57819 LSM2; U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"27258 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"25804 LSM4; U6 snRNA-associated Sm-like protein LSm4 isoform 1\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"23658 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform a\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"11157 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"51690 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"51691 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"147700 KLC3; kinesin light chain 3\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"3831 KLC1; kinesin light chain 1 isoform 2\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"64837 KLC2; kinesin light chain 2 isoform 1\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"89953 KLC4; kinesin light chain 4 isoform a\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"4644 MYO5A; unconventional myosin-Va isoform 1\tK10357 MYO5; myosin V"
					},
					{
						"name":"4645 MYO5B; unconventional myosin-Vb\tK10357 MYO5; myosin V"
					},
					{
						"name":"55930 MYO5C; unconventional myosin-Vc\tK10357 MYO5; myosin V"
					},
					{
						"name":"10376 TUBA1B; tubulin alpha-1B chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"112714 TUBA3E; tubulin alpha-3E chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"113457 TUBA3D; tubulin alpha-3D chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"51807 TUBA8; tubulin alpha-8 chain isoform 1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"7277 TUBA4A; tubulin alpha-4A chain isoform 1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"7278 TUBA3C; tubulin alpha-3C chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"7846 TUBA1A; tubulin alpha-1A chain isoform 1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"79861 TUBAL3; tubulin alpha chain-like 3 isoform 1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"80086 TUBA4B; tubulin-like protein alpha-4B\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"84790 TUBA1C; tubulin alpha-1C chain isoform c\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"132864 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform C\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"22849 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform 1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"64506 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"80315 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform a\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"25929 GEMIN5; gem-associated protein 5 isoform 1\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"10460 TACC3; transforming acidic coiled-coil-containing protein 3 isoform 1\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"23112 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform 1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"27327 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform 1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"57690 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform 1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"23019 CNOT1; CCR4-NOT transcription complex subunit 1 isoform a\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"4848 CNOT2; CCR4-NOT transcription complex subunit 2 isoform a\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"4849 CNOT3; CCR4-NOT transcription complex subunit 3 isoform 1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"4850 CNOT4; CCR4-NOT transcription complex subunit 4 isoform d\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"246175 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform 1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"57472 CNOT6; CCR4-NOT transcription complex subunit 6 isoform 1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"29883 CNOT7; CCR4-NOT transcription complex subunit 7 isoform 1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"9337 CNOT8; CCR4-NOT transcription complex subunit 8 isoform 1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"9710 GARRE1; granule associated Rac and RHOG effector protein 1\tK26671 GARRE1; granule associated Rac and RHOG effector protein 1"
					},
					{
						"name":"129563 DIS3L2; DIS3-like exonuclease 2 isoform 1\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"9924 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"255967 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"10140 TOB1; protein Tob1 isoform 1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"10766 TOB2; protein Tob2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"10950 BTG3; protein BTG3 isoform b\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"54766 BTG4; protein BTG4 isoform 1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"694 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"7832 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"56478 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform a\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"219988 PATL1; protein PAT1 homolog 1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"80153 EDC3; enhancer of mRNA-decapping protein 3 isoform 1\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"23644 EDC4; enhancer of mRNA-decapping protein 4 isoform 2\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"339345 NANOS2; nanos homolog 2\tK18760 NANOS2; protein nanos 2"
					},
					{
						"name":"342977 NANOS3; nanos homolog 3\tK18761 NANOS3; protein nanos 3"
					},
					{
						"name":"26019 UPF2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"65109 UPF3B; regulator of nonsense transcripts 3B isoform 1\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"65110 UPF3A; regulator of nonsense transcripts 3A isoform hUpf3p\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"6737 TRIM21; E3 ubiquitin-protein ligase TRIM21\tK10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]"
					},
					{
						"name":"131405 TRIM71; E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
					},
					{
						"name":"5436 POLR2G; DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"5610 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform a\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]"
					},
					{
						"name":"326340 ZAR1; zygote arrest protein 1\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"646799 ZAR1L; protein ZAR1-like\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"253943 YTHDF3; YTH domain-containing family protein 3 isoform a\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"51441 YTHDF2; YTH domain-containing family protein 2 isoform 1\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"54915 YTHDF1; YTH domain-containing family protein 1\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"7072 TIA1; cytotoxic granule associated RNA binding protein TIA1 isoform 2\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"7073 TIAL1; nucleolysin TIAR isoform 1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"132430 PABPC4L; polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"140886 PABPC5; polyadenylate-binding protein 5\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"26986 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"340529 PABPC1L2A; polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"5042 PABPC3; polyadenylate-binding protein 3\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"645974 PABPC1L2B; polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"80336 PABPC1L; polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"8761 PABPC4; polyadenylate-binding protein 4 isoform 2\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"27067 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform a\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"6780 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform b\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"2332 FMR1; fragile X messenger ribonucleoprotein 1 isoform ISO1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"8087 FXR1; RNA-binding protein FXR1 isoform a\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"9513 FXR2; RNA-binding protein FXR2\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"81030 ZBP1; Z-DNA-binding protein 1 isoform a\tK12965 ZBP1; Z-DNA binding protein 1"
					},
					{
						"name":"1994 ELAVL1; ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"10146 G3BP1; ras GTPase-activating protein-binding protein 1\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"9908 G3BP2; ras GTPase-activating protein-binding protein 2 isoform a\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"83939 EIF2A; eukaryotic translation initiation factor 2A isoform 1\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"8662 EIF3B; eukaryotic translation initiation factor 3 subunit B isoform 1\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"1973 EIF4A1; eukaryotic initiation factor 4A-I isoform 1\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"1974 EIF4A2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"9775 EIF4A3; eukaryotic initiation factor 4A-III isoform 1\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"1975 EIF4B; eukaryotic translation initiation factor 4B isoform 2\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"1981 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform 5\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"1982 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform 1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"8672 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform 3\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"27330 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform 2\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"6195 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform a\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"6196 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform a\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"6197 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform 1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"10399 RACK1; small ribosomal subunit protein RACK1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"7186 TRAF2; TNF receptor-associated factor 2\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
					},
					{
						"name":"10482 NXF1; nuclear RNA export factor 1 isoform 1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"56000 NXF3; nuclear RNA export factor 3\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"56001 NXF2; nuclear RNA export factor 2\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"728343 NXF2B; nuclear RNA export factor 2\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"10013 HDAC6; protein deacetylase HDAC6 isoform b\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					},
					{
						"name":"81550 TDRD3; tudor domain-containing protein 3 isoform 2\tK18404 TDRD3; tudor domain-containing protein 3"
					},
					{
						"name":"113251 LARP4; la-related protein 4 isoform a\tK18763 LARP4; la-related protein 4"
					},
					{
						"name":"23185 LARP4B; la-related protein 4B isoform 1\tK18763 LARP4; la-related protein 4"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"55802 DCP1A; mRNA-decapping enzyme 1A isoform a\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"196513 DCP1B; mRNA-decapping enzyme 1B isoform 1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"167227 DCP2; m7GpppN-mRNA hydrolase isoform 1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"1656 DDX6; probable ATP-dependent RNA helicase DDX6 isoform 1\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"80153 EDC3; enhancer of mRNA-decapping protein 3 isoform 1\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"23644 EDC4; enhancer of mRNA-decapping protein 4 isoform 2\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"219988 PATL1; protein PAT1 homolog 1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"27257 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"57819 LSM2; U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"27258 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"25804 LSM4; U6 snRNA-associated Sm-like protein LSm4 isoform 1\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"23658 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform a\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"11157 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"51690 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"51691 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"54464 XRN1; 5'-3' exoribonuclease 1 isoform a\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"22803 XRN2; 5'-3' exoribonuclease 2 isoform 2\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"131870 NUDT16; U8 snoRNA-decapping enzyme isoform 2\tK16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"28960 DCPS; m7GpppX diphosphatase isoform 2\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"9931 HELZ; probable helicase with zinc finger domain isoform 1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"51013 EXOSC1; exosome complex component CSL4 isoform a\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"23404 EXOSC2; exosome complex component RRP4 isoform 1\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"51010 EXOSC3; exosome complex component RRP40 isoform 1\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"54512 EXOSC4; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"56915 EXOSC5; exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"118460 EXOSC6; exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"23016 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"11340 EXOSC8; exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"5393 EXOSC9; exosome complex component RRP45 isoform 2\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"22894 DIS3; exosome complex exonuclease RRP44 isoform a\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"115752 DIS3L; DIS3-like exonuclease 1 isoform 1\tK18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"5394 EXOSC10; exosome complex component 10 isoform 1\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"10438 C1D; nuclear nucleic acid-binding protein C1D\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"10200 MPHOSPH6; M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type"
					},
					{
						"name":"55601 DDX60; probable ATP-dependent RNA helicase DDX60 isoform 1\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]"
					},
					{
						"name":"91351 DDX60L; probable ATP-dependent RNA helicase DDX60-like isoform 1\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"11044 TENT4A; terminal nucleotidyltransferase 4A isoform 1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"64282 TENT4B; terminal nucleotidyltransferase 4B isoform a\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"84186 ZCCHC7; zinc finger CCHC domain-containing protein 7\tK12597 AIR1_2; protein AIR1\/2"
					},
					{
						"name":"23517 MTREX; exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"6499 SKIC2; superkiller complex protein 2\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"9652 SKIC3; superkiller complex protein 3\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"80349 SKIC8; superkiller complex protein 8 isoform a\tK12602 WDR61; WD repeat-containing protein 61"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"246175 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform 1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"57472 CNOT6; CCR4-NOT transcription complex subunit 6 isoform 1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"23019 CNOT1; CCR4-NOT transcription complex subunit 1 isoform a\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"4848 CNOT2; CCR4-NOT transcription complex subunit 2 isoform a\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"4849 CNOT3; CCR4-NOT transcription complex subunit 3 isoform 1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"4850 CNOT4; CCR4-NOT transcription complex subunit 4 isoform d\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"29883 CNOT7; CCR4-NOT transcription complex subunit 7 isoform 1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"9337 CNOT8; CCR4-NOT transcription complex subunit 8 isoform 1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"9125 CNOT9; CCR4-NOT transcription complex subunit 9 isoform 2\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"25904 CNOT10; CCR4-NOT transcription complex subunit 10 isoform 1\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"9924 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"255967 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"154197 PNLDC1; poly(A)-specific ribonuclease PNLDC1 isoform 2\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"5073 PARN; poly(A)-specific ribonuclease PARN isoform 1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"170506 DHX36; ATP-dependent DNA\/RNA helicase DHX36 isoform 1\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]"
					},
					{
						"name":"10140 TOB1; protein Tob1 isoform 1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"10766 TOB2; protein Tob2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"10950 BTG3; protein BTG3 isoform b\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"54766 BTG4; protein BTG4 isoform 1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"694 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"7832 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"1437 CSF2; granulocyte-macrophage colony-stimulating factor precursor\tK05427 CSF2; granulocyte-macrophage colony-stimulating factor"
					},
					{
						"name":"25819 NOCT; nocturnin\tK18764 NOCT; nocturnin [EC:3.1.3.108]"
					},
					{
						"name":"90459 ERI1; 3'-5' exoribonuclease 1 isoform 1\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"112479 ERI2; ERI1 exoribonuclease 2 isoform 1\tK18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]"
					},
					{
						"name":"28960 DCPS; m7GpppX diphosphatase isoform 2\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"201626 PDE12; 2',5'-phosphodiesterase 12 isoform 1 precursor\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]"
					},
					{
						"name":"3658 IREB2; iron-responsive element-binding protein 2 isoform 1\tK22416 IREB2; iron-responsive element-binding protein 2"
					},
					{
						"name":"9931 HELZ; probable helicase with zinc finger domain isoform 1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					},
					{
						"name":"85441 HELZ2; 3'-5' exoribonuclease HELZ2 isoform 1\tK25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]"
					},
					{
						"name":"55051 NRDE2; nuclear exosome regulator NRDE2\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"23034 SAMD4A; protein Smaug homolog 1 isoform 1\tK27396 SMG; protein Smaug"
					},
					{
						"name":"55095 SAMD4B; protein Smaug homolog 2 isoform a\tK27396 SMG; protein Smaug"
					},
					{
						"name":"54914 FOCAD; focadhesin isoform 1\tK27498 FOCAD; focadhesin"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases",
					"children":[
					{
						"name":"6035 RNASE1; ribonuclease pancreatic precursor\tK01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]"
					},
					{
						"name":"6036 RNASE2; non-secretory ribonuclease precursor\tK01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]"
					},
					{
						"name":"6037 RNASE3; eosinophil cationic protein precursor\tK10787 RNASE3; eosinophil cationic protein [EC:3.1.27.-]"
					},
					{
						"name":"6038 RNASE4; ribonuclease 4 precursor\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]"
					},
					{
						"name":"122665 RNASE8; ribonuclease 8 precursor\tK01172 RNASE6_7_8; ribonuclease 6\/7\/8 [EC:3.1.27.-]"
					},
					{
						"name":"6039 RNASE6; ribonuclease K6 precursor\tK01172 RNASE6_7_8; ribonuclease 6\/7\/8 [EC:3.1.27.-]"
					},
					{
						"name":"84659 RNASE7; ribonuclease 7 precursor\tK01172 RNASE6_7_8; ribonuclease 6\/7\/8 [EC:3.1.27.-]"
					},
					{
						"name":"122651 RNASE11; putative inactive ribonuclease 11 precursor\tK16633 RNASE11; ribonuclease 11 [EC:3.1.27.-]"
					},
					{
						"name":"340152 ZC3H12D; probable ribonuclease ZC3H12D\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"340554 ZC3H12B; probable ribonuclease ZC3H12B\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"80149 ZC3H12A; endoribonuclease ZC3H12A isoform a\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"85463 ZC3H12C; probable ribonuclease ZC3H12C isoform 1\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"29102 DROSHA; ribonuclease 3 isoform 1\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"25996 REXO2; oligoribonuclease, mitochondrial precursor\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"2023 ENO1; alpha-enolase isoform 1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"2026 ENO2; gamma-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"2027 ENO3; beta-enolase isoform 1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"87178 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
					},
					{
						"name":"5211 PFKL; ATP-dependent 6-phosphofructokinase, liver type isoform b\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"5213 PFKM; ATP-dependent 6-phosphofructokinase, muscle type isoform 2\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"5214 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform 1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"3313 HSPA9; stress-70 protein, mitochondrial precursor\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"3329 HSPD1; 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"23404 EXOSC2; exosome complex component RRP4 isoform 1\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"51013 EXOSC1; exosome complex component CSL4 isoform a\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"54512 EXOSC4; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"23016 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}
