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Comment |
 CYP inhbitors
|
|
|
CYP inducers
|
|
|
 CYP substrates
|
CYP1A1 [HSA:1543]
|
CYP1A2 [HSA:1544]
|
CYP1B1 [HSA:1545]
|
CYP2A6 [HSA:1548]
|
CYP2B6 [HSA:1555]
|
CYP2C8 [HSA:1558]
|
CYP2C9 [HSA:1559]
|
Amiodarone [DG:DG00204]
|
Ampiroxicam
|
Armodafinil
|
Cimetidine [DG:DG00017]
|
Benzbromarone
|
Bepridil [DG:DG00333]
|
Bosentan [DG:DG00266]
|
Candesartan [DG:DG00350]
|
Capecitabine
|
Carvedilol [DG:DG00321]
|
Celecoxib
|
Sensitive (in vivo) |
Cyclophosphamide [DG:DG00675]
|
Dabrafenib
|
Delavirdine [DG:DG00662]
|
Diclofenac [DG:DG00441]
|
Dronabinol
|
Entacapone
|
Etizolam
|
Etravirine
|
Fluconazole [DG:DG00371]
|
Fluoxetine [DG:DG00942]
|
Flurbiprofen
|
 D00330 Flurbiprofen (JP17/USP/INN)
D02290 Flurbiprofen sodium (USP)
D01475 Flurbiprofen axetil (JAN)
D10254 Esflurbiprofen (JAN)
|
|
Fluvastatin [DG:DG00354]
|
Fosamprenavir [DG:DG00656]
|
Fosphenytoin [DG:DG00847]
|
Glibenclamide
|
Glimepiride
|
Glipizide
|
Hexobarbital
|
Ibuprofen [DG:DG00245]
|
Imatinib [DG:DG00710]
|
Irbesartan
|
Leflunomide
|
Lornoxicam
|
Losartan [DG:DG00348]
|
Losartan and diuretics
|
Mefenamic acid
|
Meloxicam
|
Miconazole [DG:DG00004]
|
Modafinil
|
Mofezolac
|
Montelukast [DG:DG01066]
|
Naproxen [DG:DG00455]
|
Naratriptan [DG:DG00837]
|
Nateglinide
|
Nelfinavir [DG:DG00655]
|
Phenytoin [DG:DG00846]
|
Narrow therapeutic range (in vivo) |
Phenytoin, combinations
|
Piroxicam [DG:DG00752]
|
Pitavastatin [DG:DG01838]
|
Quazepam
|
Rosiglitazone [DG:DG00116]
|
Sarpogrelate
|
Sertraline [DG:DG00945]
|
Sildenafil [DG:DG00484]
|
Simvastatin
|
Sorafenib [DG:DG00713]
|
Suprofen
|
Tamoxifen [DG:DG00734]
|
Terbinafine [DG:DG00375]
|
Tenoxicam
|
Tolbutamide [DG:DG00115]
|
Torasemide [DG:DG00273]
|
Tranilast
|
Trimethadione
|
Valproic acid [DG:DG00849]
|
Valsartan
|
Vardenafil [DG:DG00487]
|
Voriconazole
|
Warfarin [DG:DG00149]
|
Narrow therapeutic range (in vivo) |
Zolpidem [DG:DG00922]
|
CYP2C18 [HSA:1562]
|
CYP2C19 [HSA:1557]
|
CYP2D6 [HSA:1565]
|
CYP2J2 [HSA:1573]
|
CYP3A4 [HSA:1576]
|
CYP3A5 [HSA:1577]
|
CYP3A7 [HSA:1551]
|
CYP3A [HSA:1576 1577 1551]
|
CYP4B1 [HSA:1580]
|
|
|
Transporter inhibitors
|
|
|
Transporter inducers
|
|
|
Transporter substrates
|
Drug interactions with metabolizing enzymes and transporters