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Remark |
 G Protein-coupled receptors
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Cytokine receptors
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Nuclear receptors
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Ion channels
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Transporters
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 Enzymes
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Oxidoreductases
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alcohol dehydrogenase [HSA:124 125 126] [KO:K13951]
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aldose reductase [HSA:231] [KO:K00011]
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hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase [HSA:3156] [KO:K00021]
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3beta-hydroxysteroid dehydrogenase type 1 [HSA:3283] [KO:K00070]
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hydroxysteroid (11-beta) dehydrogenase 1 [HSA:3290] [KO:K00071]
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IMP dehydrogenase [HSA:3614 3615] [KO:K00088]
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vitamin-K-epoxide reductase [HSA:79001] [KO:K05357]
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aldehyde dehydrogenase [HSA:217 219 224] [KO:K00128]
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dihydropyrimidine dehydrogenase [HSA:1806] [KO:K00207]
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dihydroorotate dehydrogenase (DHODH) [HSA:1723] [KO:K00254]
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5alpha-reductase 1 [HSA:6715] [KO:K12343]
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5alpha-reductase 2 [HSA:6716] [KO:K12344]
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5alpha-reductase 3 [HSA:79644] [KO:K12345]
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monoamine oxidase (MAO) [HSA:4128 4129] [KO:K00274]
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monoamine oxidase A (MAO-A) [HSA:4128] [KO:K00274]
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monoamine oxidase B (MAO-B) [HSA:4129] [KO:K00274]
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dihydrofolate reductase [HSA:1719 200895] [KO:K00287]
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phylloquinone reductase [HSA:1728] [KO:K00355]
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glutathione-disulfide reductase [HSA:2936] [KO:K00383]
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thyroid peroxidase [HSA:7173] [KO:K00431]
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4-hydroxyphenylpyruvate dioxygenase [HSA:3242] [KO:K00457]
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arachidonate 5-lipoxygenase [HSA:240] [KO:K00461]
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indoleamine 2,3-dioxygenase [HSA:3620 169355] [KO:K00463]
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prolyl 4-hydroxylase [HSA:5033 8974 283208] [KO:K00472]
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hypoxia-inducible factor prolyl hydroxylase [HSA:112398 112399 54583] [KO:K09592]
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inducible nitric oxide synthase (iNOS) [HSA:4843] [KO:K13241]
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nitric oxide synthase (NOS) [HSA:4842 4843 4846] [KO:K13240 K13241 K13242]
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CYP3A [HSA:1551 1576 1577 64816] [KO:K07424]
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aromatase [HSA:1588] [KO:K07434]
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steroid 11beta-monooxygenase (CYP11B1) [HSA:1584] [KO:K00497]
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tyrosine 3-monooxygenase [HSA:7054] [KO:K00501]
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dopamine beta-hydroxylase [HSA:1621] [KO:K00503]
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tyrosinase [HSA:7299] [KO:K00505]
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cyclooxygenase-1 (COX-1) [HSA:5742] [KO:K00509]
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Benzydamine [DG:DG00014]
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Acetylsalicylic acid [DG:DG00015]
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Indometacin [DG:DG00241]
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Ibuprofen [DG:DG00245]
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Diclofenac [DG:DG00441]
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Naproxen [DG:DG00455]
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Phenylbutazone [DG:DG00745]
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Oxyphenbutazone [DG:DG00746]
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Tolmetin [DG:DG00747]
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Proglumetacin [DG:DG00750]
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Ketorolac [DG:DG00751]
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Piroxicam [DG:DG00752]
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Ketoprofen [DG:DG00753]
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Fenoprofen [DG:DG00754]
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Flurbiprofen [DG:DG00755]
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Dexibuprofen [DG:DG00756]
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Flufenamic acid [DG:DG00757]
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Meclofenamic acid [DG:DG00758]
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Felbinac [DG:DG00764]
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Amfenac [DG:DG01249]
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Piketoprofen [DG:DG01250]
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Loxoprofen [DG:DG01251]
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Aloxiprin
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Alminoprofen
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Dexketoprofen
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Acemetacin
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Ampiroxicam
|
Diflunisal
|
Carprofen
|
Firocoxib
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Lornoxicam
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Indobufen
|
Magnesium salicylate
|
Mefenamic acid
|
Mofezolac
|
Nepafenac
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Oxaprozin
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Pamicogrel
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Phenbutazone
|
Pranoprofen
|
 D01578 Pranoprofen (JP17/INN)
|
Inhibitor
|
Pravadoline
|
Salicylamide
|
Salicylic acid
|
Salsalate
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Sulindac
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Tenoxicam
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Tiaprofenic acid
|
Triflusal
|
Tolfenamic acid
|
Zaltoprofen
|
cyclooxygenase-2 (COX-2) [HSA:5743] [KO:K11987]
|
Benzydamine [DG:DG00014]
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Acetylsalicylic acid [DG:DG00015]
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Indometacin [DG:DG00241]
|
Ibuprofen [DG:DG00245]
|
Diclofenac [DG:DG00441]
|
Naproxen [DG:DG00455]
|
Phenylbutazone [DG:DG00745]
|
Oxyphenbutazone [DG:DG00746]
|
Tolmetin [DG:DG00747]
|
Proglumetacin [DG:DG00750]
|
Ketorolac [DG:DG00751]
|
Piroxicam [DG:DG00752]
|
Ketoprofen [DG:DG00753]
|
Fenoprofen [DG:DG00754]
|
Flurbiprofen [DG:DG00755]
|
Dexibuprofen [DG:DG00756]
|
Flufenamic acid [DG:DG00757]
|
Meclofenamic acid [DG:DG00758]
|
Parecoxib [DG:DG00759]
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Felbinac [DG:DG00764]
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Bromfenac [DG:DG01128]
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Amfenac [DG:DG01249]
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Piketoprofen [DG:DG01250]
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Loxoprofen [DG:DG01251]
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Aceclofenac
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Acemetacin
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Alminoprofen
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Aloxiprin
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Ampiroxicam
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Apricoxib
|
Celecoxib
|
Dexketoprofen
|
Valdecoxib
|
Lumiracoxib
|
Nabumetone
|
Salsalate
|
Diflunisal
|
Floctafenine
|
Nepafenac
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Carprofen
|
Darbufelone
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Deracoxib
|
Eltenac
|
Etodolac
|
Etoricoxib
|
Firocoxib
|
Indobufen
|
Lornoxicam
|
Magnesium salicylate
|
Mavacoxib
|
Mefenamic acid
|
Meloxicam
|
Niflumic acid
|
Nimesulide
|
Oxaprozin
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Pamicogrel
|
Phenbutazone
|
Polmacoxib
|
Pranoprofen
|
D01578 Pranoprofen (JP17/INN)
|
Inhibitor
|
Pravadoline
|
Rofecoxib
|
Salicylamide
|
Salicylic acid
|
Sulindac
|
Tiaprofenic acid
|
Tilmacoxib
|
Tenoxicam
|
Tolfenamic acid
|
Zaltoprofen
|
CYP17 [HSA:1586] [KO:K00512]
|
xanthine dehydrogenase/oxidase [HSA:7498] [KO:K00106]
|
ribonucleotide reductase [HSA:6240 6241 50484] [KO:K10807 K10808]
|
ribonucleotide reductase M1 [HSA:6240] [KO:K10807]
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ribonucleotide reductase M2 [HSA:6241] [KO:K10808]
|
type I iodothyronine deiodinase [HSA:1733] [KO:K01562]
|
type II iodothyronine deiodinase [HSA:1734] [KO:K01562]
|
Transferases
|
Hydrolases
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Lyases
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Isomerases
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Protein kinases
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Cytokines
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Others
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Target-based Classification of Drugs