Chromosome and Associated Proteins - Nannospalax galili (Upper Galilee mountains blind mole rat)

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     KO
 Eukaryotic type
   Sister chromatid cohesion proteins
   Meiosis-specific proteins
   Nucleosome assembly factors
   Histone modification proteins
     HATs (histone acetyltransferases)
     HAT complexes
     HDACs (histone deacetylases)
     HDAC complexes
     HMTs (histone methyltransferases)
       HKMTs (histone lysine methyltransferases)
         103750808 Ash1l; ASH1 like histone lysine methyltransferase
         103737299 Dot1l; DOT1 like histone lysine methyltransferase
         103724422 Ehmt2; euchromatic histone lysine methyltransferase 2
         103732609 Ehmt1; euchromatic histone lysine methyltransferase 1
         103735912 Ezh1; enhancer of zeste 1 polycomb repressive complex 2 subunit
         103731383 Ezh2; enhancer of zeste 2 polycomb repressive complex 2 subunit
         103748298 Kmt2a; lysine methyltransferase 2A
         103750570 Kmt2d; lysine methyltransferase 2D
         103745326 Kmt2c; lysine methyltransferase 2C
         103729965 Kmt2b; lysine methyltransferase 2B
         103732191 Kmt2e; lysine methyltransferase 2E
         103732357 Nsd1; nuclear receptor binding SET domain protein 1
         103745768 Nsd3; nuclear receptor binding SET domain protein 3
         103752332 Prdm2; PR/SET domain 2
         103731713 Mecom; MDS1 and EVI1 complex locus protein EVI1
         103738642 Prdm6; PR/SET domain 6
         103742349 Prdm9; PR/SET domain 9
         103735028 Znf488; zinc finger protein 488
         103742624 Prdm8; PR/SET domain 8
         103727742 Prdm12; PR/SET domain 12
         103749783 Prdm16; PR/SET domain 16
         103726333 Setd1a; SET domain containing 1A
         103739104 Setd1b; SET domain containing 1B
         103732034 Setd2; SET domain containing 2
         103736429 Setd4; SET domain containing 4
         103735123 Setd6; SET domain containing 6
         103742371 Setd7; SET domain containing lysine methyltransferase 7
         103739033 Kmt5a; lysine methyltransferase 5A
         103730089 Setdb1; SET domain bifurcated 1
         103727170 Setdb2; SET domain bifurcated 2
         103751200 histone-lysine N-methyltransferase SETMAR
         103737043 Smyd1; SET and MYND domain containing 1
         103727065 Smyd2; SET and MYND domain containing 2
         103746872 Smyd3; SET and MYND domain containing 3
         103735184 Suv39h2; suppressor of variegation 3-9 homolog 2
         103741644 Suv39h1; suppressor of variegation 3-9 homolog 1
         103744814 Kmt5c; lysine methyltransferase 5C
         103744517 Kmt5b; lysine methyltransferase 5B
K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354] 
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356] 
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356] 
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354] 
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354] 
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354] 
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354] 
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354] 
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357] 
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371] 
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355] 
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367] 
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361] 
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-] 
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359] 
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364] 
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-] 
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364] 
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361] 
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366] 
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355] 
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
       PRMTs (protein arginine metyltransferases)
     HMT complexes
       COMPASS/SET1 complex
       COMPASS/SET1 complex (yeast)
       MLL-HCF complex
       MLL3/MLL4 complex
         103745326 Kmt2c; lysine methyltransferase 2C
         103729965 Kmt2b; lysine methyltransferase 2B
         103745763 Ash2l; ASH2 like histone lysine methyltransferase complex subunit
         103745772 set1/Ash2 histone methyltransferase complex subunit ASH2-like
         103748406 Dpy30; dpy-30, histone methyltransferase complex regulatory subunit
         103725958 Rbbp5; RB binding protein 5, histone lysine methyltransferase complex subunit
         103741975 Wdr5b; WD repeat domain 5B
         103742822 Wdr5; WD repeat domain 5
         103745868 Ncoa6; nuclear receptor coactivator 6
         103745372 Paxip1; PAX interacting protein 1
         103726366 Pagr1; PAXIP1 associated glutamate rich protein 1
         103731790 Kdm6a; lysine demethylase 6A
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354] 
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354] 
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2 
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2 
K14965 DPY30; protein dpy-30 
K14961 RBBP5; COMPASS component SWD1 
K14963 WDR5; COMPASS component SWD3 
K14963 WDR5; COMPASS component SWD3 
K14971 NCOA6; nuclear receptor coactivator 6 
K14972 PAXIP1; PAX-interacting protein 1 
K14973 PA1; PAXIP1-associated protein 1 
K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68] 
       Dot1-containing complex
     Histone demethylases
     Polycomb repressive complex (PRC) and associated proteins
     Sir proteins
     Other histone modification proteins
   Chromosome condensation proteins
   Centromeric chromatin formation proteins
   Heterochromatin formation proteins
   Gene silencing
   Centrosome formation proteins
   Sister chromatid separation proteins
   Chromatin remodeling factors
 
 Prokaryotic type

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Last updated: April 10, 2024