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KO |
Eukaryotic type
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Sister chromatid cohesion proteins
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Meiosis-specific proteins
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Nucleosome assembly factors
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Histone modification proteins
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HATs (histone acetyltransferases)
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HAT complexes
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HDACs (histone deacetylases)
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HDAC complexes
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HMTs (histone methyltransferases)
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HKMTs (histone lysine methyltransferases)
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103750808 Ash1l; ASH1 like histone lysine methyltransferase
103737299 Dot1l; DOT1 like histone lysine methyltransferase
103724422 Ehmt2; euchromatic histone lysine methyltransferase 2
103732609 Ehmt1; euchromatic histone lysine methyltransferase 1
103735912 Ezh1; enhancer of zeste 1 polycomb repressive complex 2 subunit
103731383 Ezh2; enhancer of zeste 2 polycomb repressive complex 2 subunit
103748298 Kmt2a; lysine methyltransferase 2A
103750570 Kmt2d; lysine methyltransferase 2D
103745326 Kmt2c; lysine methyltransferase 2C
103729965 Kmt2b; lysine methyltransferase 2B
103732191 Kmt2e; lysine methyltransferase 2E
103732357 Nsd1; nuclear receptor binding SET domain protein 1
103745768 Nsd3; nuclear receptor binding SET domain protein 3
103752332 Prdm2; PR/SET domain 2
103731713 Mecom; MDS1 and EVI1 complex locus protein EVI1
103738642 Prdm6; PR/SET domain 6
103742349 Prdm9; PR/SET domain 9
103735028 Znf488; zinc finger protein 488
103742624 Prdm8; PR/SET domain 8
103727742 Prdm12; PR/SET domain 12
103749783 Prdm16; PR/SET domain 16
103726333 Setd1a; SET domain containing 1A
103739104 Setd1b; SET domain containing 1B
103732034 Setd2; SET domain containing 2
103736429 Setd4; SET domain containing 4
103735123 Setd6; SET domain containing 6
103742371 Setd7; SET domain containing lysine methyltransferase 7
103739033 Kmt5a; lysine methyltransferase 5A
103730089 Setdb1; SET domain bifurcated 1
103727170 Setdb2; SET domain bifurcated 2
103751200 histone-lysine N-methyltransferase SETMAR
103737043 Smyd1; SET and MYND domain containing 1
103727065 Smyd2; SET and MYND domain containing 2
103746872 Smyd3; SET and MYND domain containing 3
103735184 Suv39h2; suppressor of variegation 3-9 homolog 2
103741644 Suv39h1; suppressor of variegation 3-9 homolog 1
103744814 Kmt5c; lysine methyltransferase 5C
103744517 Kmt5b; lysine methyltransferase 5B
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K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
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PRMTs (protein arginine metyltransferases)
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HMT complexes
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COMPASS/SET1 complex
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COMPASS/SET1 complex (yeast)
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MLL-HCF complex
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MLL3/MLL4 complex
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103745326 Kmt2c; lysine methyltransferase 2C
103729965 Kmt2b; lysine methyltransferase 2B
103745763 Ash2l; ASH2 like histone lysine methyltransferase complex subunit
103745772 set1/Ash2 histone methyltransferase complex subunit ASH2-like
103748406 Dpy30; dpy-30, histone methyltransferase complex regulatory subunit
103725958 Rbbp5; RB binding protein 5, histone lysine methyltransferase complex subunit
103741975 Wdr5b; WD repeat domain 5B
103742822 Wdr5; WD repeat domain 5
103745868 Ncoa6; nuclear receptor coactivator 6
103745372 Paxip1; PAX interacting protein 1
103726366 Pagr1; PAXIP1 associated glutamate rich protein 1
103731790 Kdm6a; lysine demethylase 6A
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K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
K14965 DPY30; protein dpy-30
K14961 RBBP5; COMPASS component SWD1
K14963 WDR5; COMPASS component SWD3
K14963 WDR5; COMPASS component SWD3
K14971 NCOA6; nuclear receptor coactivator 6
K14972 PAXIP1; PAX-interacting protein 1
K14973 PA1; PAXIP1-associated protein 1
K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68]
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Dot1-containing complex
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Histone demethylases
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Polycomb repressive complex (PRC) and associated proteins
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Sir proteins
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Other histone modification proteins
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Chromosome condensation proteins
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Centromeric chromatin formation proteins
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Heterochromatin formation proteins
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Gene silencing
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Centrosome formation proteins
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Sister chromatid separation proteins
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Chromatin remodeling factors
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Prokaryotic type
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