Search BRITE hierarchies

KEGG Orthology (KO) [BR:ko00001]
  09100 Metabolism
    09104 Nucleotide metabolism
      00230 Purine metabolism [PATH:ko00230]
        K18437  PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
  09150 Organismal Systems
    09152 Endocrine system
      04927 Cortisol synthesis and secretion [PATH:ko04927]
        K18437  PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
  09160 Human Diseases
    09165 Substance dependence
      05032 Morphine addiction [PATH:ko05032]
        K18437  PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
    09167 Endocrine and metabolic disease
      04934 Cushing syndrome [PATH:ko04934]
        K18437  PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]

Enzymes [BR:ko01000]
  3. Hydrolases
    3.1  Acting on ester bonds
      3.1.4  Phosphoric-diester hydrolases
        3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
          K18437  PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]