| Entry |
Thumbnail Image |
Name |
Description |
Object |
Legend |
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hsa01212
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Fatty acid metabolism |
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...16 (ACSBG2) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 33... |
FATTY ACID METABOLISM Acetyl-CoA Acetyl-[acp] Malonyl-CoA Malonyl-[acp] Butanoyl-[acp] (AcACP) (Ma... |
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hsa04922
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Glucagon signaling pathway |
Glucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical ... |
...140 (PDE3B) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 52... |
GLUCAGON SIGNALING PATHWAY GLUT1/2 Glucose G6P Pyruvate Glucose Citrate cycle (TCA cycle) Citrate ... |
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hsa05415
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Diabetic cardiomyopathy |
Diabetic cardiomyopathy has been defined as left ventricular dysfunction that occurs among patients ... |
...01 (COX4I2), 9167 (COX7A2L), 9377 (COX5A) 1375 (CPT1B) 948 (CD36) 5164 (PDK2), 5165 (PDK3), 5166 (PD... |
FFA FFA LCFA-CoA DAG PKCα/δ FAT/CD36 Cer PP2A DIABETIC CARDIOMYOPATHY PKCβ Glucose Glucose UDP-GlcNA... |
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hsa00071
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Fatty acid degradation |
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...37 (ACADVL) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 1376 (CPT2) 217 (ALDH2), 219 (ALDH1B1), 223 (... |
1.3.99.- 1.3.99.- 1.3.99.- 1.3.99.- 1.3.99.- 1.3.99.- 1.3.8.1 1.1.1.35 4.2.1.17 1.3.8.7 6.2.1.20 5.3... |
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hsa03320
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PPAR signaling pathway |
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated... |
...1376 (CPT2) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 2180 (ACSL1), 2181 (ACSL3), 2182 (ACSL4), 232... |
Unsaturated fatty acid Unsaturated fatty acid Saturated fatty acid Eicosanoid Fibrate drug NSAID 9-c... |
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hsa04148
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Efferocytosis |
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...4953 (ODC1) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 7386 (UQCRFS1) 102 (ADAM10), 6868 (ADAM17), 8... |
ADGRB1 MERTK DOCK1 Rac1 GULP1 ELMO Actin polymerization ITGA STAB ITGB MFGE8 Efferocyte AXL FAK CRK ... |
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hsa04152
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AMPK signaling pathway |
AMP-activated protein kinase (AMPK) is a serine threonine kinase that is highly conserved through ev... |
... 31 (ACACA) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 5207 (PFKFB1), 5208 (PFKFB2), 5209 (PFKFB3), ... |
AMPK INS Glucose INSR Akt P13K PDK1/2 IRS PIP AMPK SIGNALING PATHWAY Glycolysis / Gluconeogenesis ... |
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hsa04714
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Thermogenesis |
Thermogenesis is essential for warm-blooded animals, ensuring normal cellular and physiological func... |
...346 (PLIN1) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 9658 (ZNF516) 23028 (KDM1A) 26291 (FGF21) 273... |
THERMOGENESIS CREB PKA p38 β3-AR ATF2 cAMP Acyl-CoA FGF21 UCP1 PGC-1α Mitochondrion Nucleus UCP1 Sec... |
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hsa04920
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Adipocytokine signaling pathway |
Increased adipocyte volume and number are positively correlated with leptin production, and negative... |
...021 (SOCS3) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 2538 (G6PC1), 57818 (G6PC2), 92579 (G6PC3) 51... |
Ceramide Long-chain fatty acid Retinoic acid NF-κB IκB SHP-2 SOCS3 CPT-1 G6PC PEPCK FACS Diglyceride... |
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hsa04931
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Insulin resistance |
Insulin resistance is a condition where cells become resistant to the effects of insulin. It is ofte... |
...TPA) 3569 (IL6) 6774 (STAT3) 9021 (SOCS3) 1375 (CPT1B) 4792 (NFKBIA) 4790 (NFKB1), 5970 (RELA) 5579 ... |
JNK1 TNFα FFA ER stress TNFR1 FATPs FFA IKKβ mTOR S6K INSR IRS-1 PI3K AKT2 GSK-3 +py LCFA-CoA DAG PK... |
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hsa04936
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Alcoholic liver disease |
Alcoholic liver disease (ALD) refers to the damages to the liver and its functions due to alcohol ov... |
... 31 (ACACA) 126129 (CPT1C), 1374 (CPT1A), 1375 (CPT1B) 6720 (SREBF1) 2194 (FASN) 31 (ACACA) 6319 (SC... |
MyD88 TRAF3 IFN-β IFN-α TAK1 IRAK1 IL-8 TIRAP IL-1β TBK1 TRAF6 IKKε IL-6 TAB1 TAB2 IκBα TNFα IRF3 MD... |