| Entry |
Thumbnail Image |
Name |
Description |
Object |
Legend |
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hsa01100
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Metabolic pathways |
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... (ACOT8), 10998 (SLC27A5) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
Monoterpenoid biosynthesis One carbon pool by folate Flavonoid biosynthesis Starch and sucrose metab... |
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hsa00190
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Oxidative phosphorylation |
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...67 (COX7A2L) 1345 (COX6C) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
F-type ATPase (Eukaryotes) V/A-type ATPase (Bacteria, Archaea) V-type ATPase (Eukaryotes) F-type ATP... |
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hsa04260
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Cardiac muscle contraction |
Contraction of the heart is a complex process initiated by the electrical excitation of cardiac myoc... |
...1349 (COX7B), 1350 (COX7C), 1351 (COX8A), 1537 (CYC1), 170712 (COX7B2), 27089 (UQCRQ), 29796 (UQCR10... |
CARDIAC MUSCLE CONTRACTION T-tubule Sarcoplasmic Reticulum (SR) DHPR RyR2 NCX NCX Systole Diastole... |
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hsa04714
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Thermogenesis |
Thermogenesis is essential for warm-blooded animals, ensuring normal cellular and physiological func... |
... (COX11), 1355 (COX15), 137682 (NDUFAF6), 1537 (CYC1), 170712 (COX7B2), 25915 (NDUFAF3), 27089 (UQCR... |
THERMOGENESIS CREB PKA p38 β3-AR ATF2 cAMP Acyl-CoA FGF21 UCP1 PGC-1α Mitochondrion Nucleus UCP1 Sec... |
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hsa04932
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Non-alcoholic fatty liver disease |
Non-alcoholic fatty liver disease (NAFLD) represents a spectrum ranging from simple steatosis to mor... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
NON-ALCOHOLIC FATTY LIVER DISEASE Simple steatosis (without inflammation and fibrosis) (Cirrhos... |
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hsa05010
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Alzheimer disease |
Alzheimer disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cogniti... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
PEN2 PSEN NCSTN APH-1 γ-Secretase BACE ADAM10/17 β-Secretase α-Secretase TNF Microglia AICD C99 sAPP... |
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hsa05012
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Parkinson disease |
Parkinson disease (PD) is a progressive neurodegenerative movement disorder that results primarily f... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
LRRK2 Ubiquitin mediated proteolysis Proteasome Apoptosis UBA1 UbcH7/8 Parkin CDCrel1 synphilin1 Pae... |
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hsa05014
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Amyotrophic lateral sclerosis |
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by a progressive d... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
SOD1 EAAT2 AMYOTROPHIC LATERAL SCLEROSIS Motor neuron Astrocyte Presynaptic neuron Microglial cell... |
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hsa05016
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Huntington disease |
Huntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects m... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
HUNTINGTON DISEASE Cx I Cx II Cx III Cx IV Cx V Htt Htt Htt Htt Htt REST REST coREST Sin3A HDACs DN... |
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hsa05020
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Prion disease |
Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal n... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
PrP PRION DISEASE DNA Endoplasmic reticulum (ER) Neuron Endocytosis Proteasome Golgi Early endosome... |
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hsa05022
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Pathways of neurodegeneration - multiple diseases |
Neurodegeneration is generally defined as progressive, irreversible loss of neurons, which may affec... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
PATHWAYS OF NEURODEGENERATION - MULTIPLE DISEASES Endoplasmic reticulum (ER) PrP ER stress CASP... |
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hsa05208
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Chemical carcinogenesis - reactive oxygen species |
It is well established that cancer is a multi-step process which involves initiation, promotion and ... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
CHEMICAL CARCINOGENESIS - REACTIVE OXYGEN SPECIES CYP1A2 4-Aminobiphenyl N-Hydroxy-4-aminobiphe... |
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hsa05415
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Diabetic cardiomyopathy |
Diabetic cardiomyopathy has been defined as left ventricular dysfunction that occurs among patients ... |
... 6391 (SDHC), 6392 (SDHD) 10975 (UQCR11), 1537 (CYC1), 27089 (UQCRQ), 29796 (UQCR10), 440567 (UQCRHL... |
FFA FFA LCFA-CoA DAG PKCα/δ FAT/CD36 Cer PP2A DIABETIC CARDIOMYOPATHY PKCβ Glucose Glucose UDP-GlcNA... |