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Name |
Description |
Object |
Legend |
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hsa05168
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Herpes simplex virus 1 infection |
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal ... |
..., 3717 (JAK2) 3458 (IFNG) 6732 (SRPK1) 10929 (SRSF8), 6426 (SRSF1), 6427 (SRSF2), 6428 (SRSF3), 6429... |
HERPES SIMPLEX VIRUS 1 INFECTION Herpes simplex virus-1 LTα LIGHT HVEM Nectin PILRα Heparan sulf... |
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hsa04060
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Cytokine-cytokine receptor interaction |
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulat... |
...NFRSF18) 7293 (TNFRSF4) 3604 (TNFRSF9) 943 (TNFRSF8) 939 (CD27) 958 (CD40) 355 (FAS) 8771 (TNFRSF6B)... |
...L6ST IL31 IL31RA OSMR IL1RN IL1F5 IL1F6 IL1F7 IL1F8 IL1F9 IL1F10 IL33 IL1RAP IL1RL2 ST2 Non-classifi... |
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hsa03040
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Spliceosome |
After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. ... |
...(HNRNPM), 5093 (PCBP1) 10772 (SRSF10), 10929 (SRSF8), 29896 (TRA2A), 6426 (SRSF1), 6427 (SRSF2), 642... |
complex pre-mRNA Exon 5' splice site 3' splice site Branch point complex complex complex B* Post-spl... |
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hsa00590
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Arachidonic acid metabolism |
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...YP2J2) 127281 (PRXL2B) 1557 (CYP2C19) 11283 (CYP4F8) 1571 (CYP2E1) 2879 (GPX4) 3248 (HPGD) 145482 (P... |
... diols CYP2J 1.11.1.20 CYP4A11 CYP4A CYP2C19 CYP4F8 CYP2E 1.1.1.- 1.11.1.12 15-Keto-PGD2 1.1.1.196 1... |
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hsa03022
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Basal transcription factors |
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...6878 (TAF6) 54457 (TAF7L), 6879 (TAF7) 129685 (TAF8) 51616 (TAF9B), 6880 (TAF9) 6881 (TAF10) 6882 (T... |
...FACTORS TBP TAF1 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TAF10 TAF11 TFIIB TFIIA1 TFIIA2 TFII-I TFII... |
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hsa04340
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Hedgehog signaling pathway |
The Hedgehog (Hh) signaling pathway has numerous roles in the control of cell proliferation, tissue ... |
...L2) 595 (CCND1), 894 (CCND2) 596 (BCL2) 1954 (MEGF8) 23295 (MGRN1) 730094 (MOSMO) 64399 (HHIP) 55733... |
...ation of Hh target genes CCND BCL2 CCND BCL2 MEGF8 MGRN1 Internalization ATTHOG Hhip HHAT EFCAB7 IQ... |
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hsa04610
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Complement and coagulation cascades |
The complement system is a proteolytic cascade in blood plasma and a mediator of innate immunity, a ... |
...2161 (F12) 2160 (F11) 2158 (F9) 7450 (VWF) 2157 (F8) 2159 (F10) 2147 (F2) 2153 (F5) 2243 (FGA), 2244... |
...hway Tissue damage F7a F12a F12 F11 F11a F9a VWF F8a F10a F10 F2a (Thrombin) F5a Fibrin monomer Fib... |
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hsa05133
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Pertussis |
Pertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bact... |
...) 3592 (IL12A), 3593 (IL12B) 3586 (IL10) 3394 (IRF8) 3659 (IRF1) 834 (CASP1) 114548 (NLRP3) 3592 (IL... |
...ke receptor signaling pathway CD14 IL-12 IL-10 IRF8 IRF1 DNA K efflux CASP1 NALP3 p38, ERK activat... |
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hsa01100
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Metabolic pathways |
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...1531 (UPP2), 7378 (UPP1) 57733 (GBA3) 11283 (CYP4F8), 113612 (CYP2U1), 1557 (CYP2C19), 1571 (CYP2E1)... |
Monoterpenoid biosynthesis One carbon pool by folate Flavonoid biosynthesis Starch and sucrose metab... |
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hsa04010
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MAPK signaling pathway |
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in... |
..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 2277 (VEGFD), 2323 ... |
LPS RasGRF MKP PTP PP2CB FASL DAG cAMP HGK cPLA2 STMN1 Tau NFκB IKK NIK ERK MP1 MEK2 MEK1 Raf1 RafB ... |
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hsa04014
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Ras signaling pathway |
The Ras proteins are GTPases that function as molecular switches for signaling pathways regulating c... |
..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 2277 (VEGFD), 2323 ... |
MAPK signaling pathway RAS SIGNALING PATHWAY ERK MEK Raf-1 Ras PI3K-Akt signaling pathway Grb2 SOS... |
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hsa04015
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Rap1 signaling pathway |
Rap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction fo... |
..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 2277 (VEGFD), 26281... |
MAPK signaling pathway RAP1 SIGNALING PATHWAY ERK MEK Raf-1 Rap1 RIAM RTK RalGDS Rac RapL MEK3,6 p... |
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hsa04020
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Calcium signaling pathway |
Ca2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is dr... |
..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 2277 (VEGFD), 26281... |
Long term depression Long term potentiation Phosphatidylinositol signaling pathway Apoptosis ... |
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hsa04144
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Endocytosis |
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins... |
...028 (VPS36) 7251 (TSG101) 84313 (VPS25) 11267 (SNF8) 79643 (CHMP6) 100526767 (RNF103-CHMP3), 51652 (... |
ENDOCYTOSIS STAM Hrs PI(3)P PI(3)P ESCRT-I ESCRT-0 ESCRT-II ESCRT-III Late endosome and multivesicul... |
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hsa04151
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PI3K-Akt signaling pathway |
The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellul... |
..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 2277 (VEGFD), 2323 ... |
PIP eIF4E 4EBPs eIF4B S6K1/2 Raptor mTOR GβL Rheb TSC2 TSC1 AKT PDK1 PI3K p53 signaling pathway mTOR... |
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hsa04714
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Thermogenesis |
Thermogenesis is essential for warm-blooded animals, ensuring normal cellular and physiological func... |
...2), 25915 (NDUFAF3), 27089 (UQCRQ), 284184 (NDUFAF8), 285521 (COX18), 28958 (COA3), 29078 (NDUFAF4),... |
THERMOGENESIS CREB PKA p38 β3-AR ATF2 cAMP Acyl-CoA FGF21 UCP1 PGC-1α Mitochondrion Nucleus UCP1 Sec... |
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hsa04810
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Regulation of actin cytoskeleton |
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..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 26281 (FGF20), 2629... |
PIP PIP PIP Acetylcholine TMSB4 Arp2/3 PFN WAVE2 WAVE1 HSPC300 APC NWASP Asef Abi2 Nap125 PIR121 IRS... |
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hsa05200
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Pathways in cancer |
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..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 26281 (FGF20), 2629... |
PATHWAYS IN CANCER DCC CASP3 CASP9 CASP3 ECAD β-catenin Wnt α-catenin β-catenin ITGB Dvl ECM ITGA ... |
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hsa05207
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Chemical carcinogenesis - receptor activation |
Carcinogenesis is a multistage process that consists of initiation, promotion, and progression stage... |
..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 26281 (FGF20), 2700... |
CHEMICAL CARCINOGENESIS - RECEPTOR ACTIVATION EGFR DNA Ras Raf MEK ERK1/2 DNA PKA pCREB MAPK sig... |
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hsa05218
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Melanoma |
Melanoma is a form of skin cancer that has a poor prognosis and which is on the rise in Western popu... |
..., 2250 (FGF5), 2251 (FGF6), 2252 (FGF7), 2253 (FGF8), 2254 (FGF9), 2255 (FGF10), 26281 (FGF20), 2629... |
p53 signaling pathway Melanogenesis BRAF ECAD Adherens junction NRAS CDK4 CyclinD1 MITF PTEN RTK Bad... |