KEGG image  Prodrugs

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Prodrug Active form Reaction class Reactant pair
(Pathway map)
   Chemical structure transformation pattern
KEGG ID Name KEGG ID Name
C07049
D08070
DG00928
Imipramine C06943
D07791
Desipramine RC00181 C07049_C06943 png
C07108
D08559
DG00734
Tamoxifen C16547 Endoxifen RC00181
RC00490
C07108_C16546
C16546_C16547
(map00982)
png
C06174
DG01076
Codeine C01516
D08233
Morphine RC00392 C06174_C01516
(map00982)
png
D00426 Risperidone C21516
D05339
Paliperidone RC00277 D00426_C21516 png
D01518 Alfacalcidol C01673
D00129
Calcitriol RC00963 D01518_C01673 png
C07371
D00474
Primidone C07434
D00506
Phenobarbital C07371_C07434 png
D01244 Tegafur C07649
D00584
Fluorouracil RC00063 C12673_C07649
(map00983)
png
C07888
D07760
DG00675
Cyclophosphamide C07643 4-Hydroxycyclophosphamide RC02241 C07888_C07643
(map00982)
png
C07047
D00343
Ifosfamide C16553 4-Hydroxyifosfamide RC01203 C07047_C16553
(map00982)
png
D10704 Evofosfamide C21578 Bromo-isophosphoramide mustard RC02242 D10704_C21578 png
D05868 Sodium phenylbutyrate C07086 Phenylacetate D05868_C07086 png
C00355
D00059
Levodopa C03758
D07870
Dopamine RC00299 C00355_C03758
(map00350)
png
C12739
D01309
Doxifluridine C07649
D00584
Fluorouracil RC00063 C12739_C07649
(map00983)
png
D03690 Desciclovir C06810
D00222
Aciclovir D03690_C06810 png
D00317 Famciclovir C07417
D05407
Penciclovir D00317_C07417 png
D01981 Ximelagatran C21551
D07143
Melagatran D01981_C21551 png
D00359 Lovastatin C21130 Lovastatin acid D00359_C21130 png
D00434 Simvastatin C21581 Simvastatin acid D00434_C21581 png
D01633 Enocitabine C02961
D00168
Cytarabine RC00416 D01633_C02961 png
D03046 Cytarabine ocfosphate C02961
D00168
Cytarabine C21596_C02961 png
D07377
DG01060
Bambuterol C07129
D08570
Terbutaline D07377_C07129 png
C06963
D01017
DG01129
Dipivefrin C00788
D00095
Adrenaline (Epinephrine) RC02393 C06963_C00788 png
D07294
DG00828
Propacetamol C06804
D00217
Acetaminophen RC00476 D07294_C06804 png
D08664
DG00647
Valaciclovir C06810
D00222
Aciclovir RC00041 D08664_C06810 png
D02495
DG00649
Valganciclovir C07019
D00333
Ganciclovir RC00041 D02495_C07019 png
D10894
DG02199
Valtorcitabine C21554
D06196
Torcitabine RC00055 D10894_C21554 png
C12796
D01361
Erythromycin ethylsuccinate C01912
D00140
Erythromycin RC00055 C12796_C01912 png
D02525 Erythromycin propionate C01912
D00140
Erythromycin RC00055 D02525_C01912 png
C21595
(D02523)
Erythromycin acistrate C01912
D00140
Erythromycin RC00055 C21595_C01912 png
D05351
DG00604
Josamycin propionate C12662
D01235
Josamycin RC00055 D05351_C12662 png
D05340
DG00907
Paliperidone palmitate C21516
D05339
Paliperidone RC00055 D05340_C21516 png
C07955
D00792
Fluphenazine enanthate C07010
D07977
Fluphenazine RC00041 C07955_C07010 png
C07956
D00793
Fluphenazine decanoate C07010
D07977
Fluphenazine RC00041 C07956_C07010 png
D01898
DG00885
Haloperidol decanoate C01814
D00136
Haloperidol D01898_C01814 png
C11727
D07675
DG00399
Chloramphenicol succinate C00918
D00104
Chloramphenicol RC00041 C11727_C00918 png
C11726
D01072
Chloramphenicol palmitate C00918
D00104
Chloramphenicol RC00041 C11726_C00918 png
D07674 Chloramphenicol stearate C00918
D00104
Chloramphenicol RC00041 D07674_C00918 png
C21598
(D09547)
Laninamivir octanoate C21557
D09410
Laninamivir RC00041 C21598_C21557 png
C21594
(D01990)
Clindamycin palmitate C06914
D00277
Clindamycin RC00055 C21594_C06914 png
C06534
D07286
DG01003
Diamorphine (Heroin) C01516
D08233
Morphine RC01611 C06534_C01516 png
D07285
DG00812
Nicomorphine C01516
D08233
Morphine RC01611 D07285_C01516 png
D10612
DG01850
Benzhydrocodone C08024
D08045
Hydrocodone D10612_C08024 png
D01794
DG00310
Bopindolol C21520 18-502 D07537_C21520 png
C16641
D08086
DG00726
Irinotecan C11173 SN-38 RC00476 C16641_C11173
(map00983)
png
C07908
D00752
DG00739
Mycophenolate mofetil C20380
D05096
Mycophenolic acid RC00020 C07908_C20380 png
D01122 Ibuprofen piconol C01588
D00126
Ibuprofen RC00020 D01122_C01588 png
D02199
DG00443
Carfecillin C06869
D07614
Carbenicillin RC00475 C11752_C06869 png
D08329 Penethamate hydriodide C05551
D02336
Benzylpenicillin RC00020 D08329_C05551 png
D01565 Indometacin farnesil C01926
D00141
Indometacin RC00020 D01565_C01926 png
D01582 Acemetacin C01926
D00141
Indometacin RC00020 D01582_C01926 png
D07304 Melevodopa C00355
D00059
Levodopa RC00460 D07304_C00355 png
D01132 Tazarotene C21518 Tazarotenic acid RC00020 D01132_C21518 png
D00383 Trandolapril C21515 Trandolaprilat RC00020 D00383_C21515 png
C07707
D00624
DG00337
Perindopril C21517 Perindoprilat RC00020 C07706_C21517 png
C07398
D03752
DG00338
Quinapril C21540
D03773
Quinaprilat RC00020 C07398_C21540 png
C06843
D07499
DG00339
Benazepril C21541
D03077
Benazeprilat RC00020 C06843_C21541 png
D07699
DG00340
Cilazapril C17309 Cilazaprilat RC00020 D07699_C17309 png
D08566
DG00345
Temocapril C11373 Temocaprilat RC00020 D08566_C11373 png
C06977
D07892
DG00335
Enalapril C11720 Enalaprilat RC00020 C06977_C11720 png
D08068
DG00347
Imidapril C21519 Imidaprilat RC00020 D08068_C21519 png
D07781
DG00343
Delapril C21575 Delaprilat RC00020 D07781_C21575 png
D01900 Alacepril C06867
D00251
Captopril D01900_C06867 png
D08688
DG00346
Zofenopril C21576 Zofenoprilat RC00004 D08688_C21576 png
C07016
D07992
DG00341
Fosinopril C21542
D03772
Fosinoprilat C07016_C21542 png
D01853 Miproxifene phosphate C21549 Miproxifene D01853_C21549 png
D01907 Fludarabine phosphate C21550
D07966
Fludarabine D01907_C21550 png
D02497
DG00656
Fosamprenavir C08086
D00894
Amprenavir D02497_C08086 png
C13031
D02398
DG00724
Estramustine phosphate sodium C11228
D04066
Estramustine C13031_C11228 png
C08145
D00946
DG00466
Diethylstilbestrol diphosphate C07620
D00577
Diethylstilbestrol RC01436 C08145_C07620 png
C11728
D01073
DG00435
Clindamycin phosphate C06914
D00277
Clindamycin C11728_C06914 png
D01429
DG00371
Fosfluconazole C07002
D00322
Fluconazole RC01439 D01429_C07002 png
C07840
D07993
DG00847
Fosphenytoin C07443
D00512
Phenytoin C07840_C07443 png
D04257 Fospropofol disodium C07523
D00549
Propofol RC01372 D04257_C07523 png
D10707
DG01860
Fostemsavir C21558
D10734
Temsavir RC00856 D10707_C21558 png
D06597
DG02200
Fosaprepitant C21555
D02968
Aprepitant D10895_C21555 png
D01784 Carmofur C07649
D00584
Fluorouracil RC01908 D01784_C07649
(map00983)
png
C07659
D02440
Phthalylsulfathiazole C11169
D01047
Sulfathiazole RC00416 C07659_C11169 png
C11745
D07060
DG00088
Succinylsulfathiazole C11169
D01047
Sulfathiazole RC00416 C11745_C11169 png
D07562
DG01214
Alatrofloxacin C07664
D08654
Trovafloxacin RC00166 D07562_C07664 png
D03716
DG00759
Parecoxib C21552
D02709
Valdecoxib D03716_C21552 png
D08130
DG00973
Lisdexamfetamine C07884
D03740
Dextroamphetamine (Dexamfetamine) D08130_C07884 png
D10896
DG02201
Pomaglumetad methionil C21577 LY404039 D10896_C21577 png
D08220
DG00224
Midodrine C21521 Deglymidodrine RC00096 D08220_C21521 png
C01956
D00144
Pyrazinamide C19915 Pyrazinoic acid (POA) RC00100 C01956_C19915 png
D10428 Tenofovir alafenamide C17407 Tenofovir D10428_C17407 png
C13480
(D01982)
Tenofovir disoproxil C17407 Tenofovir C13480_C17407 png
D01655 Adefovir dipivoxil C11277
D02768
Adefovir D01655_C11277 png
D10355 Aripiprazole cavoxil C12564
D01164
Aripiprazole D10355_C12564 png
D10364 Aripiprazole lauroxil C12564
D01164
Aripiprazole D10364_C12564 png
D01397 Ampiroxicam C01608
D00127
Piroxicam RC03192 D01397_C01608 png
D08861 Arbaclofen placarbil C21605
D09791
Arbaclofen (R-Baclofen) RC00744 D08861_C21605 png
D09539 Gabapentin enacarbil C07018
D00332
Gabapentin RC00744 D09539_C07018 png
C07709
D00626
Candesartan cilexetil C07468
D00522
Candesartan RC00094 C07709_C07468 png
D01475 Flurbiprofen axetil C07013
D00330
Flurbiprofen RC00094 D01475_C07013 png
C08107
D00914
Cefuroxime axetil C06894
D00262
Cefuroxime RC00094 C08107_C06894 png
D03431 Cefuroxime pivoxetil C06894
D00262
Cefuroxime RC00094 D03431_C06894 png
C08115
D00920
Cefpodoxime proxetil C08114
D07650
Cefpodoxime RC00094 C08115_C08114 png
C12861
(D01415)
Cefotiam hexetil C21544
D07648
Cefotiam RC00094 C12861_C21544 png
D01628 Cefditoren pivoxil C21546
D07639
Cefditoren D01628_C21546 png
D01686 Cefteram pivoxil C21548
D07655
Cefteram RC00020 D01686_C21548 png
C13141
(D01680)
Cefcapene pivoxil C21547
D07638
Cefcapene RC00020 C13141_C21547 png
C21592
(D09793)
Ceftizoxime alapivoxil C06890
D07658
Ceftizoxime C21592_C06890 png
D02889
DG00523
Pivmecillinam C21545
D02888
Mecillinam RC00020 D02889_C21545 png
D09598 Tebipenem pivoxil C21522 Tebipenem RC00020 D09598_C21522 png
C08122
D07487
DG00522
Bacampicillin C06574
D00204
Ampicillin RC00094 C08122_C06574 png
C11750
D08396
DG00518
Pivampicillin C06574
D00204
Ampicillin RC00020 C11750_C06574 png
D05805 Sarmoxicillin C06827
D07452
Amoxicillin D05805_C06827 png
C11729
D01074
DG00532
Hetacillin C06574
D00204
Ampicillin C11729_C06574 png
D01144 Prulifloxacin C14492 Ulifloxacin D01144_C14492 png
D01204 Olmesartan medoxomil C21543
D05246
Olmesartan RC00020 D01204_C21543 png
D01602 Mepitiostane C12694
D01265
Epitiostanol RC00077 D01602_C12694 png
D01903 Docarpamine C03758
D07870
Dopamine D01903_C03758 png
D07144 Dabigatran etexilate C21556
D09707
Dabigatran D07144_C21556 png
D07061 Acediasulfone sodium C07666
D00592
Dapsone RC00121 D07061_C07666 png
D07446 Amfetaminil C07514
D07445
Amphetamine RC00283 D07446_C07514 png
D10715 Mipsagargin C21580 12ADT-Asp RC00141 D10715_C21580 png


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Last updated: April 2, 2018