KEGG Organisms
KEGG GENOME has been a collection of KEGG organisms (see release history), which are the organisms with known complete genome sequences supplemented by those with massive EST datasets (see also KEGG GENES).
KEGG GENOME is being extended in three ways.
First, it now contains metagenomes representing environmental samples (ecosystems) of genome sequences for multiple species.
Second, KEGG organisms with high-quality KOALA annotation can now be combined computationally to examine, for example, reconstructed pathways for pangenomes and organism groups.
Third, virus genomes will be integrated and virus genes will be annotated.
KEGG Mapping for Genome Comparison and Combination
An organism group may be defined to compare or combine KEGG organisms, enabling the analysis of combined pathway maps for the group.
| (Genome comparison) |
| hsa eco |
Homo sapiens (human) vs. Escherichia coli K-12 strain
such as Terpenoid backbone biosynthesis
where green for human, red for E.coli, and split for both |
| (Host-microbiome relationship) |
| hsa+T30003 |
Homo sapiens (human) + gut microbiome
such as Global metabolism map
where green for human, red for gut microbiome, and blue for both |
| (Host-symbiont relationship) |
| dlja+mlo |
Lotus japonicus (lotus) + Mesorhizobium loti |
| api+buc |
Acyrthosiphon pisum (pea aphid) + Buchnera aphidicola |
| bmy+wbm |
Brugia malayi (filaria) + Wolbachia |
| (Host-pathogen relationship) |
| hsa+pfa |
Homo sapiens (human) + Plasmodium falciparum |
| aga+pfa |
Anopheles gambiae (mosquito) + Plasmodium falciparum |
There are predefined organism groups in KEGG, such as shown below:
KEGG Taxonomy
KEGG organisms are organized in a simple hierarchy of taxonomic classification. Animals and plants are classified in somewhat more detailed hierarchies. These hierarchies are maintained as part of the KEGG BRITE database.
The interface below allows mapping of KEGG organisms to these hierarchies according to the three- or four-letter KEGG organism codes.
NCBI Taxonomy
KEGG organisms, as well as viruses, can be viewed in the NCBI taxonomy.
Given a set of NCBI taxonomy IDs, the following interface generates a taxonomy tree.
Last updated: February 1, 2012
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