| Definition : | K10563 formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] | (GenBank) mutM; Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23) (Fapy-DNA glycosylase).,This enzyme may play a significant role in processes leading to recovery from mutagenesis and/or cell death by alkylating agents. Also involved in the go system responsible for removing an oxidatively damaged form of guanine (78-dihydro-8-oxoguanine = 7-OxoG) from DNA. Can also nick DNA at apurinic/apyrimidinic sites (AP sites) (By similarity). |