SSDB Paralog Search Result

KEGG ID :hsa:10451 (287 a.a.)
Definition:vav 3 guanine nucleotide exchange factor; K05730 guanine nucleotide exchange factor VAV
Update status:T01001 (acan,actn,ast,baci,btd,cpas,dfa,dgi,fve,hdt,hhm,hpyi,hpym,hpyr,hpyu,koe,lad,lff,loa,lph,lpo,lpr,mao,mro,mtuc,mtue,mtuh,nzs,pprc,saal,sagl,sent,sfi,sly,soi,ssut,tmm,tpb : calculation not yet completed)
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Search Result : 196 hits

       Entry                                                 KO       len  SW-score  bits  identity overlap
-------------------------------------------------------------------  ----------------------------------------
hsa:7410 vav 2 guanine nucleotide exchange factor        K05730     878     892     209    0.453    309     
hsa:7409 vav 1 guanine nucleotide exchange factor        K05730     823     810     190    0.478    276     
hsa:10750 GRB2-related adaptor protein                              217     328      81    0.291    234     
hsa:5336 phospholipase C, gamma 2 (phosphatidylinositol  K05859    1265     298      74    0.322    202     
hsa:5335 phospholipase C, gamma 1 (EC:3.1.4.11)          K01116    1291     290      72    0.306    196     
hsa:2885 growth factor receptor-bound protein 2          K04364     217     271      68    0.267    232     
hsa:4145 megakaryocyte-associated tyrosine kinase (EC:2  K08888     508     228      58    0.271    210     
hsa:1399 v-crk sarcoma virus CT10 oncogene homolog (avi  K04438     303     226      57    0.290    176     
hsa:6714 v-src sarcoma (Schmidt-Ruppin A-2) viral oncog  K05704     536     221      56    0.290    162     
hsa:25 c-abl oncogene 1, non-receptor tyrosine kinase (  K06619    1130     214      55    0.293    150     
hsa:2534 FYN oncogene related to SRC, FGR, YES (EC:2.7.  K05703     537     213      54    0.282    142     
hsa:5296 phosphoinositide-3-kinase, regulatory subunit   K02649     728     213      54    0.285    165     
hsa:4690 NCK adaptor protein 1                           K07365     313     212      54    0.252    202     
hsa:7525 v-yes-1 Yamaguchi sarcoma viral oncogene homol  K05705     543     212      54    0.296    142     
hsa:2268 Gardner-Rasheed feline sarcoma viral (v-fgr) o  K08891     529     211      54    0.273    176     
hsa:27 v-abl Abelson murine leukemia viral oncogene hom  K08887    1064     204      52    0.287    150     
hsa:8440 NCK adaptor protein 2                           K07365     380     202      52    0.302    149     
hsa:6725 src-related kinase lacking C-terminal regulato  K08895     488     197      51    0.264    208     
hsa:8503 phosphoinositide-3-kinase, regulatory subunit   K02649     461     197      51    0.314    118     
hsa:9459 Rac/Cdc42 guanine nucleotide exchange factor (  K05729     776     196      51    0.481    54      
hsa:5921 RAS p21 protein activator (GTPase activating p  K04352    1047     195      50    0.302    225     
hsa:8874 Rho guanine nucleotide exchange factor (GEF) 7  K13710     803     192      50    0.490    51      
hsa:1445 c-src tyrosine kinase (EC:2.7.10.2)             K05728     450     191      49    0.269    130     
hsa:2444 fyn-related kinase (EC:2.7.10.2)                K08892     505     191      49    0.281    185     
hsa:3055 hemopoietic cell kinase (EC:2.7.10.2)           K08893     505     190      49    0.287    171     
hsa:30011 SH3-domain kinase binding protein 1            K12470     628     189      49    0.240    229     
hsa:640 B lymphoid tyrosine kinase (EC:2.7.10.2)         K08890     505     187      48    0.259    189     
hsa:10580 sorbin and SH3 domain containing 1             K06086    1292     182      47    0.519    52      
hsa:1398 v-crk sarcoma virus CT10 oncogene homolog (avi  K04438     204     182      47    0.269    193     
hsa:9402 GRB2-related adaptor protein 2                  K07366     330     182      47    0.241    162     
hsa:3932 lymphocyte-specific protein tyrosine kinase (E  K05856     509     181      47    0.263    171     
hsa:695 Bruton agammaglobulinemia tyrosine kinase (EC:2  K07370     659     180      47    0.240    242     
hsa:7006 tec protein tyrosine kinase (EC:2.7.10.2)       K07364     631     178      46    0.263    236     
hsa:152503 SH3 domain containing 19                                 790     173      45    0.268    287     
hsa:5781 protein tyrosine phosphatase, non-receptor typ  K07293     593     173      45    0.278    126     
hsa:115677 nitric oxide synthase trafficker                         506     172      45    0.423    78      
hsa:4296 mitogen-activated protein kinase kinase kinase  K04419     847     171      45    0.400    80      
hsa:5777 protein tyrosine phosphatase, non-receptor typ  K05697     595     169      44    0.288    125     
hsa:5295 phosphoinositide-3-kinase, regulatory subunit   K02649     361     168      44    0.351    97      
hsa:6453 intersectin 1 (SH3 domain protein)                        1220     167      44    0.451    51      
hsa:50944 SH3 and multiple ankyrin repeat domains 1      K15009    2161     166      44    0.390    77      
hsa:8470 sorbin and SH3 domain containing 2                         644     165      43    0.528    53      
hsa:50618 intersectin 2                                            1697     161      43    0.451    51      
hsa:84451 mixed lineage kinase 4 (EC:2.7.11.25)                    1036     161      43    0.348    89      
hsa:4067 v-yes-1 Yamaguchi sarcoma viral related oncoge  K05854     491     160      42    0.239    197     
hsa:7535 zeta-chain (TCR) associated protein kinase 70k  K07360     619     160      42    0.330    100     
hsa:7294 TXK tyrosine kinase (EC:2.7.10.2)               K08016     527     159      42    0.277    206     
hsa:79729 SH3 domain containing 21                                  756     159      42    0.231    234     
hsa:126669 Src homology 2 domain containing E                       495     158      42    0.314    105     
hsa:10174 sorbin and SH3 domain containing 3                        329     156      41    0.469    49      
hsa:2241 fer (fps/fes related) tyrosine kinase (EC:2.7.  K08889     822     156      41    0.232    198     
hsa:3059 hematopoietic cell-specific Lyn substrate 1     K06106     486     156      41    0.393    84      
hsa:25759 SHC (Src homology 2 domain containing) transf  K06279     582     151      40    0.276    105     
hsa:10603 SH2B adaptor protein 2                         K07193     675     150      40    0.238    122     
hsa:6464 SHC (Src homology 2 domain containing) transfo  K06279     584     148      40    0.282    103     
hsa:25970 SH2B adaptor protein 1                         K12459     756     147      39    0.240    175     
hsa:284948 SH2 domain containing 6                                  175     147      39    0.272    191     
hsa:393 Rho GTPase activating protein 4                             986     147      39    0.392    51      
hsa:9873 FCH and double SH3 domains 2                               740     147      39    0.434    53      
hsa:27071 dual adaptor of phosphotyrosine and 3-phospho  K12229     280     146      39    0.258    132     
hsa:6769 SH3 and cysteine rich domain                               402     146      39    0.228    79      
hsa:6850 spleen tyrosine kinase (EC:2.7.10.2)            K05855     612     146      39    0.270    111     
hsa:23607 CD2-associated protein                         K13738     639     145      39    0.385    52      
hsa:26578 osteoclast stimulating factor 1                           214     145      39    0.393    61      
hsa:285590 SH3 and PX domains 2B                                    911     145      39    0.360    50      
hsa:4293 mitogen-activated protein kinase kinase kinase  K04417    1118     145      39    0.453    53      
hsa:89848 FCH and double SH3 domains 1                              690     145      39    0.315    108     
hsa:653361 neutrophil cytosolic factor 1                 K08011     390     144      39    0.262    126     
hsa:4542 myosin IF                                       K10356    1098     143      38    0.333    78      
hsa:8190 melanoma inhibitory activity                    K16655     131     143      38    0.353    68      
hsa:6709 spectrin, alpha, non-erythrocytic 1             K06114    2477     142      38    0.283    99      
hsa:10019 SH2B adaptor protein 3                         K12459     575     140      38    0.248    105     
hsa:23380 SLIT-ROBO Rho GTPase activating protein 2      K07526    1070     139      38    0.412    51      
hsa:4294 mitogen-activated protein kinase kinase kinase  K04418     954     139      38    0.342    79      
hsa:57522 SLIT-ROBO Rho GTPase activating protein 1      K07526    1085     138      37    0.412    51      
hsa:57630 SH3 domain containing ring finger 1            K12171     888     137      37    0.325    77      
hsa:6503 Src-like-adaptor                                           276     137      37    0.201    174     
hsa:9901 SLIT-ROBO Rho GTPase activating protein 3       K07526    1075     137      37    0.412    51      
hsa:10254 signal transducing adaptor molecule (SH3 doma  K04705     525     136      37    0.284    88      
hsa:50649 Rho guanine nucleotide exchange factor (GEF)   K05769     690     136      37    0.329    73      
hsa:6461 Src homology 2 domain containing adaptor prote             509     136      37    0.284    134     
hsa:8027 signal transducing adaptor molecule (SH3 domai  K04705     540     136      37    0.287    150     
hsa:90525 Src homology 2 domain containing F                        423     136      37    0.273    183     
hsa:2888 growth factor receptor-bound protein 14                    540     135      37    0.282    85      
hsa:400581 GRB2-related adaptor protein-like                        118     135      37    0.283    106     
hsa:9051 proline-serine-threonine phosphatase interacti  K12804     416     135      37    0.373    51      
hsa:53358 SHC (Src homology 2 domain containing) transf  K06279     594     134      36    0.293    82      
hsa:23504 RIMS binding protein 2                                   1052     133      36    0.284    102     
hsa:4643 myosin IE                                       K10356    1108     133      36    0.408    49      
hsa:54806 Abelson helper integration site 1              K16740    1196     133      36    0.333    51      
hsa:85358 SH3 and multiple ankyrin repeat domains 3      K15009    1731     133      36    0.450    40      
hsa:3635 inositol polyphosphate-5-phosphatase, 145kDa (  K03084    1189     132      36    0.297    128     
hsa:3702 IL2-inducible T-cell kinase (EC:2.7.10.2)       K07363     620     132      36    0.262    187     
hsa:6456 SH3-domain GRB2-like 2                          K11247     352     132      36    0.278    90      
hsa:342667 SH3 and cysteine rich domain 2                           411     131      36    0.303    76      
hsa:6708 spectrin, alpha, erythrocytic 1 (elliptocytosi  K06114    2419     130      35    0.380    50      
hsa:221178 spermatogenesis associated 13                           1277     129      35    0.301    93      
hsa:2242 feline sarcoma oncogene (EC:2.7.10.2)           K07527     764     129      35    0.260    146     
hsa:27352 small G protein signaling modulator 3                     749     129      35    0.404    52      
hsa:23268 dynamin binding protein                                  1577     128      35    0.229    236     
hsa:4688 neutrophil cytosolic factor 2                   K08010     526     128      35    0.298    84      
hsa:8935 src kinase associated phosphoprotein 2                     359     128      35    0.439    41      
hsa:10152 abl-interactor 2                               K05751     475     127      35    0.373    51      
hsa:22941 SH3 and multiple ankyrin repeat domains 2      K15009    1849     127      35    0.425    40      
hsa:6455 SH3-domain GRB2-like 1                          K11247     320     127      35    0.380    50      
hsa:6457 SH3-domain GRB2-like 3                          K11247     347     127      35    0.354    48      
hsa:26084 Rho guanine nucleotide exchange factor (GEF)   K13744     871     126      35    0.429    56      
hsa:26751 SH3 domain containing, Ysc84-like 1 (S. cerev             323     126      35    0.272    81      
hsa:29760 B-cell linker                                  K07371     433     126      35    0.280    93      
hsa:646892 SH2 domain containing 7                                  451     125      34    0.248    109     
hsa:9655 suppressor of cytokine signaling 5              K04698     536     125      34    0.234    201     
hsa:10045 SH2 domain containing 3A                                  576     124      34    0.315    108     
hsa:3275 protein arginine methyltransferase 2 (EC:2.1.1  K11435     331     124      34    0.295    88      
hsa:10006 abl-interactor 1                                          481     123      34    0.293    82      
hsa:29763 protein kinase C and casein kinase substrate              424     123      34    0.289    83      
hsa:56961 Src homology 2 domain containing transforming             340     123      34    0.249    189     
hsa:8631 src kinase associated phosphoprotein 1                     358     123      34    0.413    46      
hsa:257364 sorting nexin 33                                         574     122      34    0.353    51      
hsa:660 BMX non-receptor tyrosine kinase (EC:2.7.10.2)   K08896     675     122      34    0.299    87      
hsa:9644 SH3 and PX domains 2A                                     1105     122      34    0.328    58      
hsa:116449 cytokine-dependent hematopoietic cell linker             428     121      33    0.294    102     
hsa:153769 SH3 domain containing ring finger 2           K12171     729     121      33    0.351    77      
hsa:4703 nebulin                                                   8525     121      33    0.341    88      
hsa:54436 SH3 domain and tetratricopeptide repeats 1               1336     121      33    0.300    100     
hsa:128272 Rho guanine nucleotide exchange factor (GEF)             802     120      33    0.232    185     
hsa:344558 SH3 domain containing ring finger 3           K12171     882     119      33    0.254    67      
hsa:3927 LIM and SH3 protein 1                                      205     119      33    0.248    157     
hsa:9306 suppressor of cytokine signaling 6              K10322     535     119      33    0.253    79      
hsa:375056 melanoma inhibitory activity family, member             1907     118      33    0.286    91      
hsa:8651 suppressor of cytokine signaling 1              K04694     211     118      33    0.342    73      
hsa:1123 chimerin 1                                                 433     117      33    0.237    93      
hsa:399694 SHC (Src homology 2 domain containing) famil  K06279     630     117      33    0.226    133     
hsa:54440 SAM and SH3 domain containing 3                           380     117      33    0.333    78      
hsa:57091 Cas scaffolding protein family member 4                   732     117      33    0.328    61      
hsa:85376 RIMS binding protein 3                                   1639     117      33    0.302    106     
hsa:11252 protein kinase C and casein kinase substrate              486     116      32    0.373    51      
hsa:150221 RIMS binding protein 3C                                 1639     116      32    0.302    106     
hsa:440804 RIMS binding protein 3B                                 1639     116      32    0.302    106     
hsa:4689 neutrophil cytosolic factor 4, 40kDa            K08012     339     115      32    0.275    80      
hsa:115703 Rho GTPase activating protein 33                        1123     113      32    0.400    65      
hsa:2887 growth factor receptor-bound protein 10                    548     113      32    0.220    182     
hsa:29993 protein kinase C and casein kinase substrate              444     113      32    0.339    56      
hsa:7984 Rho guanine nucleotide exchange factor (GEF) 5            1597     113      32    0.444    45      
hsa:10811 NADPH oxidase activator 1                                 476     112      31    0.291    55      
hsa:1793 dedicator of cytokinesis 1                      K13708    1865     112      31    0.368    57      
hsa:55971 BAI1-associated protein 2-like 1                          511     112      31    0.413    46      
hsa:8835 suppressor of cytokine signaling 2              K04695     198     112      31    0.256    82      
hsa:2059 epidermal growth factor receptor pathway subst             822     111      31    0.213    258     
hsa:80115 BAI1-associated protein 2-like 2                          529     111      31    0.395    43      
hsa:9256 benzodiazapine receptor (peripheral) associate            1848     111      31    0.385    39      
hsa:9564 breast cancer anti-estrogen resistance 1        K05726     916     111      31    0.350    60      
hsa:8573 calcium/calmodulin-dependent serine protein ki  K06103     898     110      31    0.214    229     
hsa:10137 RNA binding motif protein 12                              932     109      31    0.225    253     
hsa:122809 suppressor of cytokine signaling 4            K04697     440     109      31    0.261    115     
hsa:146760 reticulon 4 receptor-like 1                   K16660     441     109      31    0.239    134     
hsa:23677 SH3-domain binding protein 4                              963     109      31    0.317    63      
hsa:246329 SH3 and cysteine rich domain 3                           364     109      31    0.300    50      
hsa:28988 drebrin-like                                              430     109      31    0.377    53      
hsa:8491 mitogen-activated protein kinase kinase kinase  K04406     873     109      31    0.219    224     
hsa:9743 Rho GTPase activating protein 32                          2087     108      30    0.354    65      
hsa:2017 cortactin                                       K06106     634     107      30    0.413    46      
hsa:4867 nephronophthisis 1 (juvenile)                              733     107      30    0.346    52      
hsa:4901 neural retina leucine zipper                    K09038     237     107      30    0.268    127     
hsa:56904 SH3-domain GRB2-like endophilin B2             K11248     395     107      30    0.333    63      
hsa:389337 Rho guanine nucleotide exchange factor (GEF)             675     106      30    0.359    64      
hsa:1154 cytokine inducible SH2-containing protein       K04701     275     105      30    0.263    95      
hsa:1288 collagen, type IV, alpha 6                      K06237    1691     105      30    0.366    71      
hsa:2318 filamin C, gamma                                K04437    2692     105      30    0.267    150     
hsa:23368 protein phosphatase 1, regulatory subunit 13B            1090     105      30    0.333    51      
hsa:23644 enhancer of mRNA decapping 4                   K12616    1401     105      30    0.220    168     
hsa:2886 growth factor receptor-bound protein 7                     532     105      30    0.228    184     
hsa:80005 dedicator of cytokinesis 5                     K05727    1870     105      30    0.383    60      
hsa:84174 Src-like-adaptor 2                                        261     105      30    0.254    142     
hsa:112574 sorting nexin 18                                         624     104      30    0.370    54      
hsa:23328 SAM and SH3 domain containing 1                          1247     104      30    0.387    62      
hsa:3636 inositol polyphosphate phosphatase-like 1 (EC:  K15909    1258     104      30    0.298    84      
hsa:56914 otoraplin                                                 128     104      30    0.328    67      
hsa:57524 CASK interacting protein 1                               1431     104      30    0.316    57      
hsa:5753 protein tyrosine kinase 6 (EC:2.7.10.2)         K08894     134     104      30    0.353    68      
hsa:6452 SH3-domain binding protein 2                    K07984     561     104      30    0.224    210     
hsa:8412 breast cancer anti-estrogen resistance 3                   825     104      30    0.304    56      
hsa:257397 TGF-beta activated kinase 1/MAP3K7 binding p  K12793     712     103      29    0.301    93      
hsa:79574 EPS8-like 3                                               563     103      29    0.316    95      
hsa:84941 hematopoietic SH2 domain containing                       352     103      29    0.289    83      
hsa:64787 EPS8-like 2                                               715     102      29    0.340    50      
hsa:85446 zinc finger homeobox 2                         K09379    2572     102      29    0.333    60      
hsa:10188 tyrosine kinase, non-receptor, 2 (EC:2.7.11.1  K08886    1086     101      29    0.311    45      
hsa:23199 Gse1 coiled-coil protein                                 1113     101      29    0.273    139     
hsa:27237 Rho guanine nucleotide exchange factor (GEF)              709     101      29    0.348    46      
hsa:80781 collagen, type XVIII, alpha 1                  K06823    1516     101      29    0.288    111     
hsa:25791 neuronal guanine nucleotide exchange factor    K07525     618     100      29    0.353    51      
hsa:30837 suppressor of cytokine signaling 7             K04699     581     100      29    0.253    87      
hsa:4739 neural precursor cell expressed, developmental  K16832     834     100      29    0.309    55      
hsa:51100 SH3-domain GRB2-like endophilin B1             K11248     394     100      29    0.347    49      
hsa:64092 SAM domain, SH3 domain and nuclear localizati             441     100      29    0.357    56      
hsa:8853 ArfGAP with SH3 domain, ankyrin repeat and PH   K12488     961     100      29    0.294    85
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