SSDB Paralog Search Result

KEGG ID :hsa:2889 (1077 a.a.)
Definition:Rap guanine nucleotide exchange factor (GEF) 1; K06277 Rap guanine nucleotide exchange factor 1
Update status:T01001 (abaa,abau,abk,abw,axs,babo,bamy,bhm,bmal,bsui,bthe,ced,cem,cen,cft,cfx,cgj,cgq,echp,echv,echw,ecla,eclc,efq,kln,kom,kph,kpk,kpq,kpz,law,lsj,mak,mavr,may,maz,mbz,mcat,ngi,ocu,paea,paee,paef,paeh,paej,paen,paeq,pbd,pcp,pda,pfn,pgm,pmul,pod,prh,pste,pstu,psw,sagc,seps,sgu,smia,smub,sthe,synd,synk,synr,xfl,xfs,zmc : calculation not yet completed)
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Search Result : 190 hits

       Entry                                                 KO       len  SW-score  bits  identity overlap
-------------------------------------------------------------------  ----------------------------------------
hsa:5923 Ras protein-specific guanine nucleotide-releas  K04349    1257     508     122    0.284    461     
hsa:6654 son of sevenless homolog 1 (Drosophila)         K03099    1333     473     114    0.289    401     
hsa:6655 son of sevenless homolog 2 (Drosophila)         K03099    1332     473     114    0.281    427     
hsa:5924 Ras protein-specific guanine nucleotide-releas  K12326    1237     454     109    0.317    300     
hsa:11069 Rap guanine nucleotide exchange factor (GEF)   K04351     867     415     100    0.303    244     
hsa:9771 Rap guanine nucleotide exchange factor (GEF) 5  K08019     730     391      95    0.306    232     
hsa:10125 RAS guanyl releasing protein 1 (calcium and D  K04350     762     389      95    0.238    441     
hsa:25780 RAS guanyl releasing protein 3 (calcium and D  K12362     690     388      94    0.262    359     
hsa:55103 Ral GEF with PH domain and SH3 binding motif              557     357      87    0.323    251     
hsa:9693 Rap guanine nucleotide exchange factor (GEF) 2  K08018    1499     355      87    0.323    291     
hsa:10411 Rap guanine nucleotide exchange factor (GEF)   K08014     923     352      86    0.335    179     
hsa:9649 Ral GEF with PH domain and SH3 binding motif 1             529     336      82    0.313    252     
hsa:51735 Rap guanine nucleotide exchange factor (GEF)   K08020    1609     335      82    0.354    178     
hsa:51195 Rap guanine nucleotide exchange factor (GEF)-             456     332      82    0.251    334     
hsa:10235 RAS guanyl releasing protein 2 (calcium and D  K12361     609     329      81    0.250    360     
hsa:5863 ral guanine nucleotide dissociation stimulator  K17636     695     328      81    0.263    430     
hsa:153020 RasGEF domain family, member 1B                          473     323      79    0.242    417     
hsa:266747 ral guanine nucleotide dissociation stimulat             473     315      78    0.287    282     
hsa:23179 ral guanine nucleotide dissociation stimulato  K17635     803     307      76    0.273    411     
hsa:57139 ral guanine nucleotide dissociation stimulato  K17639     710     305      75    0.301    282     
hsa:5900 ral guanine nucleotide dissociation stimulator  K08732     859     293      73    0.277    296     
hsa:102723511 adhesive plaque matrix protein-like                   590     281      70    0.245    458     
hsa:115727 RAS guanyl releasing protein 4                K12363     659     277      69    0.250    252     
hsa:255426 RasGEF domain family, member 1C                          466     273      68    0.235    426     
hsa:221002 RasGEF domain family, member 1A                          489     248      62    0.227    441     
hsa:102724633 adhesive plaque matrix protein-like                   752     247      62    0.225    480     
hsa:647024 chromosome 6 open reading frame 132                     1188     231      59    0.246    499     
hsa:23067 SET domain containing 1B (EC:2.1.1.43)         K11422    1923     228      58    0.264    444     
hsa:56252 YLP motif containing 1                         K17602    2146     228      58    0.226    681     
hsa:27445 piccolo presynaptic cytomatrix protein         K16882    4935     227      58    0.232    501     
hsa:1822 atrophin 1                                      K05626    1190     225      57    0.232    456     
hsa:11273 ataxin 2-like                                            1075     224      57    0.236    461     
hsa:132864 cytoplasmic polyadenylation element binding   K02602    1007     224      57    0.247    478     
hsa:80164 putative uncharacterized protein FLJ22184                1346     224      57    0.237    666     
hsa:23368 protein phosphatase 1, regulatory subunit 13B  K17554    1090     220      56    0.227    506     
hsa:23248 regulation of nuclear pre-mRNA domain contain            1461     219      56    0.214    518     
hsa:29998 glioma tumor suppressor candidate region gene            1560     219      56    0.232    475     
hsa:9757 lysine (K)-specific methyltransferase 2B (EC:2  K14959    2715     218      56    0.234    419     
hsa:84627 zinc finger protein 469                                  3925     215      55    0.233    455     
hsa:1387 CREB binding protein (EC:2.3.1.48)              K04498    2404     213      54    0.205    787     
hsa:8085 lysine (K)-specific methyltransferase 2D (EC:2  K09187    5537     213      54    0.246    467     
hsa:653247 proline-rich protein BstNI subfamily 2        K13911     416     212      54    0.253    450     
hsa:7082 tight junction protein 1                        K05701    1748     212      54    0.218    564     
hsa:51168 myosin XVA                                     K10361    3530     211      54    0.248    492     
hsa:8867 synaptojanin 1 (EC:3.1.3.36)                    K01099    1295     211      54    0.262    252     
hsa:23148 NAC alpha domain containing                              1562     209      53    0.229    511     
hsa:9947 melanoma antigen family C, 1                              1142     209      53    0.230    893     
hsa:10579 transforming, acidic coiled-coil containing p  K14282    2826     208      53    0.241    610     
hsa:85456 tankyrase 1 binding protein 1, 182kDa                    1729     208      53    0.227    534     
hsa:102725117 rho guanine nucleotide exchange factor 5-            1493     206      53    0.220    841     
hsa:7984 Rho guanine nucleotide exchange factor (GEF) 5            1597     206      53    0.220    841     
hsa:9612 nuclear receptor corepressor 2                  K06065    2458     206      53    0.234    611     
hsa:343990 KIAA1211-like                                            962     205      53    0.209    716     
hsa:58508 lysine (K)-specific methyltransferase 2C (EC:  K09188    4911     205      53    0.233    490     
hsa:114783 lemur tyrosine kinase 3 (EC:2.7.11.1)         K08899    1489     203      52    0.240    471     
hsa:57648 KIAA1522                                                 1035     203      52    0.233    511     
hsa:25930 protein tyrosine phosphatase, non-receptor ty  K18040    1636     202      52    0.216    677     
hsa:5542 proline-rich protein BstNI subfamily 1          K13911     331     202      52    0.260    277     
hsa:65268 WNK lysine deficient protein kinase 2 (EC:2.7  K08867    2297     202      52    0.227    397     
hsa:8660 insulin receptor substrate 2                    K07187    1338     202      52    0.241    402     
hsa:10523 calcium homeostasis endoplasmic reticulum pro  K12841     916     201      52    0.207    526     
hsa:1981 eukaryotic translation initiation factor 4 gam  K03260    1606     201      52    0.225    570     
hsa:7916 proline-rich coiled-coil 2A                               2157     200      51    0.239    535     
hsa:114785 methyl-CpG binding domain protein 6                     1003     189      49    0.250    448     
hsa:6853 synapsin I                                                 705     189      49    0.252    298     
hsa:284615 ankyrin repeat domain 34A                                496     188      49    0.275    375     
hsa:155435 RNA binding motif protein 33                            1170     187      48    0.252    484     
hsa:115703 Rho GTPase activating protein 33              K17933    1123     186      48    0.273    444     
hsa:6525 smoothelin                                                1002     185      48    0.281    274     
hsa:29109 formin homology 2 domain containing 1                    1164     183      48    0.273    161     
hsa:23616 SH3-domain binding protein 1                              701     182      47    0.266    425     
hsa:7456 WAS/WASL interacting protein family, member 1              503     181      47    0.251    402     
hsa:57555 neuroligin 2                                   K07378     835     177      46    0.253    434     
hsa:200014 coiled-coil and C2 domain containing 1B       K18260     858     176      46    0.256    523     
hsa:7917 BCL2-associated athanogene 6                              1126     175      46    0.253    221     
hsa:5544 proline-rich protein BstNI subfamily 3                     309     174      46    0.252    242     
hsa:63946 DMRT-like family C2                                       367     174      46    0.254    252     
hsa:84133 zinc and ring finger 3                         K16273     936     174      46    0.258    411     
hsa:23371 tensin like C1 domain containing phosphatase   K18080    1419     172      45    0.255    294     
hsa:4137 microtubule-associated protein tau              K04380     776     169      44    0.251    351     
hsa:23235 salt-inducible kinase 2 (EC:2.7.11.1)          K16311     926     167      44    0.268    194     
hsa:342346 chromosome 16 open reading frame 96                     1141     167      44    0.263    289     
hsa:283149 B-cell CLL/lymphoma 9-like                              1499     166      44    0.263    285     
hsa:64759 tensin 3                                       K18080    1445     166      44    0.261    357     
hsa:1281 collagen, type III, alpha 1                     K06236    1466     165      43    0.274    175     
hsa:23373 CREB regulated transcription coactivator 1     K15309     650     165      43    0.250    284     
hsa:286262 taperin                                                  711     165      43    0.281    274     
hsa:146909 kinesin family member 18B                                833     164      43    0.256    402     
hsa:23094 signal-induced proliferation-associated 1 lik  K17703    1781     164      43    0.252    404     
hsa:6595 SWI/SNF related, matrix associated, actin depe  K11647    1590     164      43    0.255    294     
hsa:1277 collagen, type I, alpha 1                       K06236    1464     163      43    0.267    251     
hsa:10021 hyperpolarization activated cyclic nucleotide  K04957    1203     162      43    0.250    344     
hsa:23187 pleckstrin homology-like domain, family B, me            1377     162      43    0.265    264     
hsa:64919 B-cell CLL/lymphoma 11B (zinc finger protein)             893     162      43    0.251    557     
hsa:389333 proline-rich basic protein 1                            1015     161      43    0.267    277     
hsa:90780 pygopus family PHD finger 2                               406     161      43    0.256    266     
hsa:1288 collagen, type IV, alpha 6                      K06237    1707     159      42    0.259    487     
hsa:146325 proline rich 35                                          571     159      42    0.264    303     
hsa:1729 diaphanous-related formin 1                     K05740    1263     159      42    0.267    210     
hsa:4026 LIM domain containing preferred translocation   K16676     612     159      42    0.250    308     
hsa:1296 collagen, type VIII, alpha 2                               638     158      42    0.257    249     
hsa:7205 thyroid hormone receptor interactor 6           K12792     476     157      42    0.250    308     
hsa:9632 SEC24 family member C                           K14007    1094     157      42    0.252    317     
hsa:147179 WAS/WASL interacting protein family, member              440     156      41    0.252    294     
hsa:10262 splicing factor 3b, subunit 4, 49kDa           K12831     424     155      41    0.262    237     
hsa:85442 kinase non-catalytic C-lobe domain (KIND) con            1749     155      41    0.251    283     
hsa:4776 nuclear factor of activated T-cells, cytoplasm  K17334     964     151      40    0.259    290     
hsa:9627 synuclein, alpha interacting protein            K04558     603     150      40    0.251    303     
hsa:144100 pleckstrin homology domain containing, famil            1121     145      39    0.333    84      
hsa:79720 vacuolar protein sorting 37 homolog B (S. cer  K12185     285     137      37    0.309    165     
hsa:752 formin-like 1                                              1100     135      37    0.318    88      
hsa:197407 zinc finger protein 48                                   618     130      35    0.303    132     
hsa:23002 dishevelled associated activator of morphogen  K04512    1068     130      35    0.329    76      
hsa:91977 myozenin 3                                                251     129      35    0.313    147     
hsa:285800 proline rich 18                                          295     126      35    0.304    138     
hsa:4037 low density lipoprotein receptor-related prote             770     126      35    0.301    146     
hsa:100652824 uncharacterized protein KIAA2012                     1180     125      34    0.301    193     
hsa:113220 kinesin family member 12                      K10399     513     123      34    0.333    108     
hsa:11189 CUGBP, Elav-like family member 3               K13207     418     121      33    0.352    88      
hsa:7425 VGF nerve growth factor inducible                          615     121      33    0.305    118     
hsa:610 hyperpolarization activated cyclic nucleotide-g  K04955     889     120      33    0.319    94      
hsa:85455 dispatched homolog 2 (Drosophila)                        1401     120      33    0.319    141     
hsa:1793 dedicator of cytokinesis 1                      K13708    1886     118      33    0.319    116     
hsa:55150 chromosome 19 open reading frame 73                       129     118      33    0.330    94      
hsa:79869 cleavage and polyadenylation specific factor   K14398     471     118      33    0.326    89      
hsa:8456 forkhead box N1                                 K09407     648     118      33    0.320    128     
hsa:22809 activating transcription factor 5              K09044     282     117      33    0.318    88      
hsa:1737 dihydrolipoamide S-acetyltransferase (EC:2.3.1  K00627     647     116      32    0.300    110     
hsa:8447 double C2-like domains, beta                               412     116      32    0.301    153     
hsa:101930339 protein piccolo-like                                   88     114      32    0.321    84      
hsa:23158 TBC1 domain family, member 9 (with GRAM domai            1266     113      32    0.319    135     
hsa:155382 vacuolar protein sorting 37 homolog D (S. ce  K12185     251     112      31    0.307    101     
hsa:23270 TSPY-like 4                                    K11287     414     112      31    0.303    109     
hsa:729627 proline rich 23A                                         266     112      31    0.355    62      
hsa:773 calcium channel, voltage-dependent, P/Q type, a  K04344    2266     112      31    0.310    84      
hsa:124535 heat shock transcription factor family membe             596     111      31    0.307    101     
hsa:55740 enabled homolog (Drosophila)                   K05746     591     111      31    0.338    71      
hsa:729238 surfactant protein A2                         K10067     248     111      31    0.300    90      
hsa:84108 polycomb group ring finger 6                   K11470     350     111      31    0.306    98      
hsa:6854 synapsin II                                                478     110      31    0.360    50      
hsa:101930098 mediator of RNA polymerase II transcripti             165     109      31    0.326    86      
hsa:3059 hematopoietic cell-specific Lyn substrate 1     K06106     449     109      31    0.323    96      
hsa:51341 zinc finger and BTB domain containing 7A       K10494     584     109      31    0.310    87      
hsa:101929941 zinc finger homeobox protein 4-like                   193     108      30    0.375    40      
hsa:389895 chromosome 16 open reading frame 72-like                 273     108      30    0.307    114     
hsa:678 ZFP36 ring finger protein-like 2                            494     108      30    0.325    120     
hsa:29941 protein kinase N3 (EC:2.7.11.13)               K06071     889     107      30    0.319    94      
hsa:7074 T-cell lymphoma invasion and metastasis 1       K05731    1591     106      30    0.320    225     
hsa:81608 factor interacting with PAPOLA and CPSF1       K14405     588     106      30    0.354    48      
hsa:101928380 glyceraldehyde-3-phosphate dehydrogenase,             135     105      30    0.319    94      
hsa:3141 holocarboxylase synthetase (biotin-(proprionyl  K01942     726     105      30    0.315    146     
hsa:8541 protein tyrosine phosphatase, receptor type, f            1194     105      30    0.351    77      
hsa:101928629 leucine-rich repeat extensin-like protein             125     104      30    0.320    103     
hsa:137735 actin-binding Rho activating protein                     381     104      30    0.301    83      
hsa:23500 dishevelled associated activator of morphogen  K04512    1068     104      30    0.317    63      
hsa:26330 glyceraldehyde-3-phosphate dehydrogenase, spe  K10705     408     104      30    0.351    57      
hsa:3976 leukemia inhibitory factor                      K05419      88     104      30    0.329    73      
hsa:57101 anoctamin 2, calcium activated chloride chann            1003     104      30    0.320    75      
hsa:7469 negative elongation factor complex member A     K15179     539     104      30    0.327    98      
hsa:83861 radial spoke 3 homolog (Chlamydomonas)                    560     104      30    0.314    86      
hsa:101928587 putative uncharacterized protein FLJ44672             165     103      29    0.317    123     
hsa:10409 brain abundant, membrane attached signal prot  K17272     227     103      29    0.301    93      
hsa:1044 caudal type homeobox 1                          K09312     265     103      29    0.315    92      
hsa:1762 dystrophia myotonica, WD repeat containing                 674     103      29    0.304    102     
hsa:22880 MORC family CW-type zinc finger 2                         970     103      29    0.338    80      
hsa:57719 anoctamin 8                                              1232     103      29    0.472    36      
hsa:9132 potassium voltage-gated channel, KQT-like subf  K04929     695     103      29    0.305    95      
hsa:101928657 basic proline-rich protein-like                       265     102      29    0.324    68      
hsa:101929994 putative uncharacterized protein FLJ44672             165     102      29    0.311    119     
hsa:144717 family with sequence similarity 109, member              262     102      29    0.312    154     
hsa:266722 heparan sulfate 6-O-sulfotransferase 3 (EC:2  K08103     471     102      29    0.328    64      
hsa:3975 LIM homeobox 1                                  K09372     406     102      29    0.325    83      
hsa:6631 small nuclear ribonucleoprotein polypeptide C   K11095     159     102      29    0.317    63      
hsa:79000 aurora kinase A and ninein interacting protei  K16800     371     102      29    0.306    134     
hsa:101929358 protein piccolo-like                                  126     101      29    0.342    38      
hsa:102724705 small nuclear ribonucleoprotein-associate             203     101      29    0.321    84      
hsa:151963 Mab-21 domain containing 2                               491     101      29    0.309    68      
hsa:1840 deltex 1, E3 ubiquitin ligase                   K06058     620     101      29    0.309    81      
hsa:22859 latrophilin 1                                  K04592    1474     101      29    0.346    81      
hsa:100996365 putative uncharacterized protein FLJ44672             165     100      29    0.309    123     
hsa:100996414 putative uncharacterized protein FLJ92257             165     100      29    0.309    123     
hsa:10664 CCCTC-binding factor (zinc finger protein)                399     100      29    0.359    64      
hsa:219287 APC membrane recruitment protein 2                       671     100      29    0.326    95      
hsa:22795 nidogen 2 (osteonidogen)                       K06826    1375     100      29    0.302    86      
hsa:254173 tubulin tyrosine ligase-like family, member              673     100      29    0.333    84      
hsa:30813 visual system homeobox 1                       K09335     236     100      29    0.409    44      
hsa:3833 kinesin family member C1                        K10405     673     100      29    0.300    140     
hsa:4692 necdin, melanoma antigen (MAGE) family member              321     100      29    0.340    100     
hsa:79797 zinc finger protein 408                                   712     100      29    0.326    86      
hsa:8711 tyrosine kinase, non-receptor, 1 (EC:2.7.10.2)  K08885     666     100      29    0.342    76      

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