SSDB Paralog Search Result

KEGG ID :hsa:7410 (878 a.a.)
Definition:vav guanine nucleotide exchange factor 2; K05730 guanine nucleotide exchange factor VAV
Update status:T01001 (agl,aoa,asq,avu,bcig,bgy,bhu,boe,btho,caby,hhsr,hsi,jaz,jeu,kba,mbf,myz,pmuc,suam,vhl,xho : calculation not yet completed)
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Search Result : 198 hits

                 Entry                                       KO      len   SW-score(margin)  bits  identity overlap  best(all)
------------------------------------------------------------------ -------------------------------------------------------------
hsa:10451 vav guanine nucleotide exchange factor 3      K05730     847     3102 (    -)     713    0.520    898      -> 
hsa:7409 vav guanine nucleotide exchange factor 1       K05730     845     2896 (    -)     666    0.499    895      -> 
hsa:80243 phosphatidylinositol-3,4,5-trisphosphate depe K17588    1606      389 (    -)      95    0.291    406      -> 
hsa:57580 phosphatidylinositol-3,4,5-trisphosphate depe K12365    1659      383 (    -)      93    0.298    342      -> 
hsa:221178 spermatogenesis associated 13                K05769     652      380 (    -)      92    0.267    404      -> 
hsa:50649 Rho guanine nucleotide exchange factor 4      K05769     690      364 (    -)      89    0.265    344      -> 
hsa:64857 pleckstrin homology and RhoGEF domain contain           1386      364 (    -)      89    0.263    486      -> 
hsa:23229 Cdc42 guanine nucleotide exchange factor 9    K20686     516      360 (    -)      88    0.254    343      -> 
hsa:26030 pleckstrin homology and RhoGEF domain contain           1219      358 (    -)      87    0.270    318      -> 
hsa:57480 pleckstrin homology and RhoGEF domain contain           1385      337 (    -)      83    0.286    252      -> 
hsa:10750 GRB2-related adaptor protein                             217      312 (    -)      77    0.248    266      -> 
hsa:8874 Rho guanine nucleotide exchange factor 7       K13710     803      308 (    -)      76    0.226    583      -> 
hsa:9459 Rac/Cdc42 guanine nucleotide exchange factor 6 K05729     776      304 (    -)      75    0.236    576      -> 
hsa:9828 Rho guanine nucleotide exchange factor 17      K20689    2063      297 (    -)      74    0.281    270      -> 
hsa:54848 Rho guanine nucleotide exchange factor 38     K20711     777      284 (    -)      71    0.219    729      -> 
hsa:89846 FYVE, RhoGEF and PH domain containing 3       K05722     725      283 (    -)      70    0.213    413      -> 
hsa:23263 MCF.2 cell line derived transforming sequence K20685    1129      282 (    -)      70    0.244    508      -> 
hsa:25791 neuronal guanine nucleotide exchange factor   K07525     710      275 (    -)      69    0.245    290      -> 
hsa:5924 Ras protein specific guanine nucleotide releas K12326    1237      274 (    -)      68    0.229    442      -> 
hsa:27237 Rho guanine nucleotide exchange factor 16     K20688     709      273 (    -)      68    0.231    368      -> 
hsa:55200 pleckstrin homology and RhoGEF domain contain            790      273 (    -)      68    0.232    522      -> 
hsa:10276 neuroepithelial cell transforming 1           K20683     596      272 (    -)      68    0.261    295      -> 
hsa:4168 MCF.2 cell line derived transforming sequence  K20685     925      268 (    -)      67    0.266    267      -> 
hsa:5923 Ras protein specific guanine nucleotide releas K04349    1273      268 (    -)      67    0.233    352      -> 
hsa:2245 FYVE, RhoGEF and PH domain containing 1        K05720     961      265 (    -)      66    0.222    460      -> 
hsa:5336 phospholipase C gamma 2                        K05859    1265      263 (    -)      66    0.282    220      -> 
hsa:50650 Rho guanine nucleotide exchange factor 3      K20683     526      261 (    -)      65    0.245    290      -> 
hsa:7204 trio Rho guanine nucleotide exchange factor    K08810    3097      261 (    -)      65    0.251    335      -> 
hsa:2885 growth factor receptor bound protein 2         K04364     217      259 (    -)      65    0.253    265      -> 
hsa:5335 phospholipase C gamma 1                        K01116    1290      258 (    -)      65    0.256    219      -> 
hsa:23268 dynamin binding protein                       K20705    1577      255 (    -)      64    0.223    813      -> 
hsa:6453 intersectin 1                                  K20045    1721      252 (    -)      63    0.232    267      -> 
hsa:8997 kalirin, RhoGEF kinase                         K15048    2986      250 (    -)      63    0.215    404      -> 
hsa:84904 Rho guanine nucleotide exchange factor 39                335      247 (    -)      62    0.223    346      -> 
hsa:121512 FYVE, RhoGEF and PH domain containing 4      K05723     766      246 (    -)      62    0.202    431      -> 
hsa:221472 FYVE, RhoGEF and PH domain containing 2      K05721     655      245 (    -)      62    0.222    419      -> 
hsa:23365 Rho guanine nucleotide exchange factor 12     K07532    1544      243 (    -)      61    0.216    305      -> 
hsa:26230 T-cell lymphoma invasion and metastasis 2     K16847    1701      243 (    -)      61    0.261    261      -> 
hsa:7074 T-cell lymphoma invasion and metastasis 1      K05731    1591      242 (    -)      61    0.235    310      -> 
hsa:389337 Rho guanine nucleotide exchange factor 37    K20710     675      238 (    -)      60    0.288    208      -> 
hsa:115557 Rho guanine nucleotide exchange factor 25    K20690     580      237 (    -)      60    0.253    289      -> 
hsa:26084 Rho guanine nucleotide exchange factor 26     K13744     871      237 (    -)      60    0.229    384      -> 
hsa:695 Bruton tyrosine kinase                          K07370     659      233 (    -)      59    0.216    385      -> 
hsa:1894 epithelial cell transforming 2                 K20704     914      232 (    -)      59    0.235    251      -> 
hsa:7525 YES proto-oncogene 1, Src family tyrosine kina K05705     543      231 (    -)      59    0.290    183      -> 
hsa:9639 Rho guanine nucleotide exchange factor 10      K16727    1368      230 (    -)      58    0.252    282      -> 
hsa:9138 Rho guanine nucleotide exchange factor 1       K12330     912      228 (    -)      58    0.231    385      -> 
hsa:4145 megakaryocyte-associated tyrosine kinase       K08888     507      226 (    -)      57    0.238    240      -> 
hsa:102725117 rho guanine nucleotide exchange factor 5- K20684    1485      225 (    -)      57    0.242    356      -> 
hsa:50618 intersectin 2                                 K20045    1697      225 (    -)      57    0.239    205      -> 
hsa:7984 Rho guanine nucleotide exchange factor 5       K20684    1597      225 (    -)      57    0.244    357      -> 
hsa:10125 RAS guanyl releasing protein 1                K04350     797      223 (    -)      57    0.245    408      -> 
hsa:9402 GRB2-related adaptor protein 2                 K07366     330      223 (    -)      57    0.261    207      -> 
hsa:9826 Rho guanine nucleotide exchange factor 11      K12331    1522      219 (    -)      56    0.209    512      -> 
hsa:5296 phosphoinositide-3-kinase regulatory subunit 2 K02649     728      218 (    -)      56    0.245    204      -> 
hsa:55160 Rho guanine nucleotide exchange factor 10 lik K16727    1279      218 (    -)      56    0.236    296      -> 
hsa:9181 Rho/Rac guanine nucleotide exchange factor 2   K12791     986      213 (    -)      54    0.217    420      -> 
hsa:9855 FERM, ARH/RhoGEF and pleckstrin domain protein K06082    1054      213 (    -)      54    0.235    378      -> 
hsa:64283 Rho guanine nucleotide exchange factor 28     K16529    1705      211 (    -)      54    0.191    361      -> 
hsa:2534 FYN proto-oncogene, Src family tyrosine kinase K05703     537      210 (    -)      54    0.298    171      -> 
hsa:345930 epithelial cell transforming 2 like                     904      209 (    -)      53    0.190    474      -> 
hsa:4690 NCK adaptor protein 1                          K07365     377      209 (    -)      53    0.299    154      -> 
hsa:660 BMX non-receptor tyrosine kinase                K08896     675      208 (    -)      53    0.204    406      -> 
hsa:3055 HCK proto-oncogene, Src family tyrosine kinase K08893     526      204 (    -)      52    0.254    224      -> 
hsa:6714 SRC proto-oncogene, non-receptor tyrosine kina K05704     536      204 (    -)      52    0.280    175      -> 
hsa:1445 c-src tyrosine kinase                          K05728     450      203 (    -)      52    0.238    160      -> 
hsa:115727 RAS guanyl releasing protein 4               K12363     673      201 (    -)      52    0.270    222      -> 
hsa:5753 protein tyrosine kinase 6                      K08894     451      201 (    -)      52    0.272    173      -> 
hsa:8440 NCK adaptor protein 2                          K19862     380      197 (    -)      51    0.289    152      -> 
hsa:2444 fyn related Src family tyrosine kinase         K08892     505      195 (    -)      50    0.288    198      -> 
hsa:2268 FGR proto-oncogene, Src family tyrosine kinase K08891     529      193 (    -)      50    0.280    189      -> 
hsa:10580 sorbin and SH3 domain containing 1            K06086    1292      190 (    -)      49    0.491    53       -> 
hsa:8470 sorbin and SH3 domain containing 2                       1100      189 (    -)      49    0.280    261      -> 
hsa:4293 mitogen-activated protein kinase kinase kinase K04417    1104      185 (    -)      48    0.456    68       -> 
hsa:4296 mitogen-activated protein kinase kinase kinase K04419     847      185 (    -)      48    0.400    85       -> 
hsa:25780 RAS guanyl releasing protein 3                K12362     690      183 (    -)      48    0.333    114      -> 
hsa:5578 protein kinase C alpha                         K02677     672      179 (    -)      47    0.256    301      -> 
hsa:56904 SH3 domain containing GRB2 like endophilin B2 K11248     395      179 (    -)      47    0.251    263      -> 
hsa:79729 SH3 domain containing 21                                 645      179 (    -)      47    0.397    78       -> 
hsa:27 ABL proto-oncogene 2, non-receptor tyrosine kina K08887    1182      177 (    -)      46    0.255    188      -> 
hsa:3932 LCK proto-oncogene, Src family tyrosine kinase K05856     509      177 (    -)      46    0.279    165      -> 
hsa:4294 mitogen-activated protein kinase kinase kinase K04418     954      177 (    -)      46    0.432    74       -> 
hsa:5781 protein tyrosine phosphatase, non-receptor typ K07293     593      175 (    -)      46    0.300    110      -> 
hsa:84451 mixed lineage kinase 4                        K17534    1036      173 (    -)      45    0.439    57       -> 
hsa:10174 sorbin and SH3 domain containing 3                       671      171 (    -)      45    0.333    111      -> 
hsa:50944 SH3 and multiple ankyrin repeat domains 1     K15009    2161      171 (    -)      45    0.314    121      -> 
hsa:1264 calponin 1                                                297      169 (    -)      44    0.340    94       -> 
hsa:5579 protein kinase C beta                          K19662     671      169 (    -)      44    0.304    138      -> 
hsa:23683 protein kinase D3                             K06070     890      168 (    -)      44    0.348    69       -> 
hsa:115677 nitric oxide synthase trafficking            K20126     506      166 (    -)      44    0.410    78       -> 
hsa:22998 LIM and calponin homology domains 1                     1083      166 (    -)      44    0.411    73       -> 
hsa:4034 leucine rich repeats and calponin homology dom            683      164 (    -)      43    0.352    88       -> 
hsa:57630 SH3 domain containing ring finger 1           K12171     888      164 (    -)      43    0.311    106      -> 
hsa:6850 spleen associated tyrosine kinase              K05855     635      164 (    -)      43    0.347    98       -> 
hsa:5582 protein kinase C gamma                         K19663     697      163 (    -)      43    0.266    139      -> 
hsa:153478 pleckstrin homology and RhoGEF domain contai           1271      162 (    -)      43    0.260    246      -> 
hsa:25865 protein kinase D2                             K06070     878      162 (    -)      43    0.383    47       -> 
hsa:23143 leucine rich repeats and calponin homology do            728      161 (    -)      43    0.326    86       -> 
hsa:89848 FCH and double SH3 domains 1                  K20125     690      161 (    -)      43    0.386    88       -> 
hsa:393 Rho GTPase activating protein 4                 K20122     946      160 (    -)      42    0.442    52       -> 
hsa:5580 protein kinase C delta                         K06068     676      160 (    -)      42    0.266    158      -> 
hsa:5587 protein kinase D1                              K06070     912      160 (    -)      42    0.354    65       -> 
hsa:4008 LIM domain 7                                   K06084    1631      159 (    -)      42    0.419    74       -> 
hsa:646892 SH2 domain containing 7                                 451      159 (    -)      42    0.337    92       -> 
hsa:126669 Src homology 2 domain containing E                      495      158 (    -)      42    0.253    154      -> 
hsa:55561 CDC42 binding protein kinase gamma            K16307    1551      158 (    -)      42    0.289    90       -> 
hsa:6456 SH3 domain containing GRB2 like 2, endophilin  K11247     352      158 (    -)      42    0.278    180      -> 
hsa:1265 calponin 2                                                309      157 (    -)      42    0.333    96       -> 
hsa:5777 protein tyrosine phosphatase, non-receptor typ K05697     595      157 (    -)      42    0.274    106      -> 
hsa:9873 FCH and double SH3 domains 2                   K20125     740      157 (    -)      42    0.472    53       -> 
hsa:160851 diacylglycerol kinase eta                    K00901    1220      156 (    -)      41    0.276    163      -> 
hsa:84174 Src like adaptor 2                                       261      155 (    -)      41    0.256    199      -> 
hsa:22852 ankyrin repeat domain 26                                1709      153 (    -)      41    0.309    123      -> 
hsa:26578 osteoclast stimulating factor 1                          214      153 (    -)      41    0.365    74       -> 
hsa:5588 protein kinase C theta                         K18052     706      152 (    -)      40    0.276    105      -> 
hsa:6769 SH3 and cysteine rich domain                              402      152 (    -)      40    0.339    59       -> 
hsa:342667 SH3 and cysteine rich domain 2                          411      151 (    -)      40    0.252    155      -> 
hsa:85358 SH3 and multiple ankyrin repeat domains 3     K15009    1731      151 (    -)      40    0.297    138      -> 
hsa:10811 NADPH oxidase activator 1                                476      150 (    -)      40    0.317    82       -> 
hsa:1124 chimerin 2                                     K20630     468      150 (    -)      40    0.353    51       -> 
hsa:1609 diacylglycerol kinase theta                    K00901     942      146 (    -)      39    0.359    64       -> 
hsa:2017 cortactin                                      K06106     550      146 (    -)      39    0.426    54       -> 
hsa:1266 calponin 3                                                329      145 (    -)      39    0.303    89       -> 
hsa:29763 protein kinase C and casein kinase substrate  K20123     424      145 (    -)      39    0.322    121      -> 
hsa:3059 hematopoietic cell-specific Lyn substrate 1    K06106     486      145 (    -)      39    0.341    85       -> 
hsa:57631 leucine rich repeats and calponin homology do            765      145 (    -)      39    0.302    96       -> 
hsa:7535 zeta chain of T cell receptor associated prote K07360     619      144 (    -)      39    0.306    147      -> 
hsa:4542 myosin IF                                      K10356    1098      143 (    -)      38    0.312    109      -> 
hsa:23380 SLIT-ROBO Rho GTPase activating protein 2     K07526    1071      142 (    -)      38    0.344    61       -> 
hsa:10152 abl interactor 2                              K05751     513      141 (    -)      38    0.358    67       -> 
hsa:5590 protein kinase C zeta                          K18952     592      140 (    -)      38    0.352    54       -> 
hsa:8027 signal transducing adaptor molecule            K04705     540      140 (    -)      38    0.400    50       -> 
hsa:285590 SH3 and PX domains 2B                                   911      138 (    -)      37    0.360    50       -> 
hsa:57522 SLIT-ROBO Rho GTPase activating protein 1     K07526    1085      138 (    -)      37    0.365    52       -> 
hsa:9051 proline-serine-threonine phosphatase interacti K12804     416      138 (    -)      37    0.365    52       -> 
hsa:6708 spectrin alpha, erythrocytic 1                 K06114    2419      137 (    -)      37    0.357    70       -> 
hsa:23025 unc-13 homolog A                              K15293    1703      136 (    -)      37    0.370    46       -> 
hsa:344558 SH3 domain containing ring finger 3          K12171     882      136 (    -)      37    0.315    89       -> 
hsa:8935 src kinase associated phosphoprotein 2                    359      136 (    -)      37    0.463    41       -> 
hsa:6876 transgelin                                     K20526     201      135 (    -)      37    0.300    90       -> 
hsa:27352 small G protein signaling modulator 3         K20176     749      133 (    -)      36    0.415    53       -> 
hsa:54806 Abelson helper integration site 1             K16740    1196      133 (    -)      36    0.333    57       -> 
hsa:1608 diacylglycerol kinase gamma                    K00901     791      132 (    -)      36    0.380    50       -> 
hsa:6709 spectrin alpha, non-erythrocytic 1             K06114    2472      132 (    -)      36    0.321    53       -> 
hsa:8190 melanoma inhibitory activity                   K16655     131      128 (    -)      35    0.358    67       -> 
hsa:10006 abl interactor 1                                         508      125 (    -)      34    0.343    67       -> 
hsa:1607 diacylglycerol kinase beta                     K00901     804      124 (    -)      34    0.306    62       -> 
hsa:8631 src kinase associated phosphoprotein 1         K17699     359      124 (    -)      34    0.436    39       -> 
hsa:11252 protein kinase C and casein kinase substrate  K20123     486      123 (    -)      34    0.325    77       -> 
hsa:1793 dedicator of cytokinesis 1                     K13708    1865      123 (    -)      34    0.394    66       -> 
hsa:23371 tensin 2                                      K18080    1409      123 (    -)      34    0.338    68       -> 
hsa:152503 SH3 domain containing 19                                790      122 (    -)      34    0.346    52       -> 
hsa:115703 Rho GTPase activating protein 33             K17933    1126      121 (    -)      33    0.354    65       -> 
hsa:4703 nebulin                                        K18267    6669      121 (    -)      33    0.355    62       -> 
hsa:3927 LIM and SH3 protein 1                                     261      120 (    -)      33    0.316    98       -> 
hsa:4689 neutrophil cytosolic factor 4                  K08012     339      119 (    -)      33    0.333    75       -> 
hsa:51225 ABI family member 3                                      366      119 (    -)      33    0.314    70       -> 
hsa:28988 drebrin like                                  K20520     430      118 (    -)      33    0.370    54       -> 
hsa:10848 protein phosphatase 1 regulatory subunit 13 l            828      114 (    -)      32    0.333    54       -> 
hsa:1287 collagen type IV alpha 5 chain                 K06237    1685      114 (    -)      32    0.330    97       -> 
hsa:29998 glioma tumor suppressor candidate region gene           1560      114 (    -)      32    0.337    104      -> 
hsa:257364 sorting nexin 33                             K17923     574      112 (    -)      31    0.346    52       -> 
hsa:29993 protein kinase C and casein kinase substrate  K20123     444      111 (    -)      31    0.310    84       -> 
hsa:4739 neural precursor cell expressed, developmental K16832     834      111 (    -)      31    0.333    54       -> 
hsa:90113 von Willebrand factor A domain containing 5B2           1242      111 (    -)      31    0.303    109      -> 
hsa:10278 embryonal Fyn-associated substrate                       561      110 (    -)      31    0.382    55       -> 
hsa:51429 sorting nexin 9                               K17923     595      110 (    -)      31    0.310    58       -> 
hsa:8522 growth arrest specific 7                       K18618     476      110 (    -)      31    0.353    51       -> 
hsa:23504 RIMS binding protein 2                        K17591    1052      109 (    -)      31    0.390    41       -> 
hsa:50807 ArfGAP with SH3 domain, ankyrin repeat and PH K12488    1129      109 (    -)      31    0.346    78       -> 
hsa:8711 tyrosine kinase non receptor 1                 K08885     666      109 (    -)      31    0.348    66       -> 
hsa:9743 Rho GTPase activating protein 32               K20647    2087      109 (    -)      31    0.328    64       -> 
hsa:54874 formin binding protein 1 like                 K20121     605      108 (    -)      30    0.333    57       -> 
hsa:80005 dedicator of cytokinesis 5                    K17707    1870      108 (    -)      30    0.407    54       -> 
hsa:815 calcium/calmodulin dependent protein kinase II  K04515     478      108 (    -)      30    0.343    105      -> 
hsa:9564 BCAR1, Cas family scaffolding protein          K05726     870      108 (    -)      30    0.317    60       -> 
hsa:5358 plastin 3                                      K17336     630      107 (    -)      30    0.333    78       -> 
hsa:10188 tyrosine kinase non receptor 2                K08886    1038      106 (    -)      30    0.310    71       -> 
hsa:3275 protein arginine methyltransferase 2           K11435     433      106 (    -)      30    0.353    51       -> 
hsa:653247 proline rich protein BstNI subfamily 2       K13911     416      106 (    -)      30    0.306    98       -> 
hsa:1289 collagen type V alpha 1 chain                  K19721    1838      105 (    -)      30    0.302    96       -> 
hsa:23526 Rho GTPase activating protein 45              K20644    1136      105 (    -)      30    0.308    52       -> 
hsa:1300 collagen type X alpha 1 chain                  K19479     680      104 (    -)      30    0.329    73       -> 
hsa:3936 lymphocyte cytosolic protein 1                 K17276     627      104 (    -)      30    0.333    78       -> 
hsa:4354 membrane palmitoylated protein 1                          466      104 (    -)      30    0.333    51       -> 
hsa:817 calcium/calmodulin dependent protein kinase II  K04515     499      104 (    -)      30    0.333    105      -> 
hsa:112574 sorting nexin 18                             K17923     628      103 (    -)      29    0.370    54       -> 
hsa:1310 collagen type XIX alpha 1 chain                          1142      103 (    -)      29    0.300    80       -> 
hsa:5555 proline rich protein HaeIII subfamily 2        K13910     166      103 (    -)      29    0.310    100      -> 
hsa:55971 BAI1 associated protein 2 like 1              K20127     511      103 (    -)      29    0.317    63       -> 
hsa:126820 WD repeat domain 63                                     891      101 (    -)      29    0.300    70       -> 
hsa:54436 SH3 domain and tetratricopeptide repeats 1              1336      101 (    -)      29    0.325    80       -> 
hsa:116986 ArfGAP with GTPase domain, ankyrin repeat an K17848    1192      100 (    -)      29    0.309    110      -> 
hsa:1263 polo like kinase 3                             K08862     646      100 (    -)      29    0.338    71       -> 
hsa:1286 collagen type IV alpha 4 chain                 K06237    1690      100 (    -)      29    0.323    65       -> 
hsa:369 A-Raf proto-oncogene, serine/threonine kinase   K08845     606      100 (    -)      29    0.319    47       -> 
hsa:5357 plastin 1                                      K17275     629      100 (    -)      29    0.317    63       -> 
hsa:9820 cullin 7                                       K10613    1698      100 (    -)      29    0.330    91       -> 

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