| Entry |
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| Name |
rosmarinate synthase;
rosmarinic acid synthase;
caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase;
4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase;
RAS (gene name)
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
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| Sysname |
caffeoyl-CoA:(R)-3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase
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| Reaction(IUBMB) |
caffeoyl-CoA + (R)-3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate [RN: R03374]
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| Reaction(KEGG) |
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| Substrate |
caffeoyl-CoA [CPD: C00323];
(R)-3-(3,4-dihydroxyphenyl)lactate [CPD: C22038]
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| Product |
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| Comment |
Involved, with EC 1.1.1.237 (hydroxyphenylpyruvate reductase) in the biosynthesis of rosmarinic acid. Characterized from the plant Melissa officinalis L. (lemon balm).
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| History |
EC 2.3.1.140 created 1992, modified 2013
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| Pathway |
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| Orthology |
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| Reference |
1 |
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| Authors |
Petersen, M. and Alfermann, A.W. |
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| Title |
Two new enzymes of rosmarinic acid biosynthesis from cell cultures of Coleus blumei: hydroxyphenylpyruvate reductase and rosmarinic acid synthase. |
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| Journal |
Z Naturforsch C: Biosci 43:501-504 (1988) |
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| Reference |
2 |
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| Authors |
Petersen, M. S. |
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| Title |
Characterization of rosmarinic acid synthase from cell cultures of Coleus blumei. |
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| Journal |
Phytochemistry 30:2877-2881 (1991) |
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| Reference |
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| Authors |
Weitzel C, Petersen M |
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| Title |
Cloning and characterisation of rosmarinic acid synthase from Melissa officinalis L. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.3.1.140 |
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| LinkDB |
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