KEGG   ENZYME: 2.4.1.191
Entry
EC 2.4.1.191                Enzyme                                 

Name
luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase;
uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase;
UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase;
UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase;
LDT;
UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-alpha-D-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-alpha-D-glucuronate + luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] = UDP + luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide [RN:R06828]
Reaction(KEGG)
R06828
Substrate
UDP-alpha-D-glucuronate [CPD:C00167];
luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] [CPD:C12632]
Product
UDP [CPD:C00015];
luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide [CPD:C04900]
Comment
The enzyme participates in the biosynthesis of luteolin triglucuronide, the major flavone found in the photosynthetically-active mesophyll of the primary leaves of Secale cereale (rye).
History
EC 2.4.1.191 created 1992, modified 2011
Pathway
ec00944  Flavone and flavonol biosynthesis
Reference
1
  Authors
Schulz, M. and Weissenbock, G.
  Title
3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale.
  Journal
Phytochemistry 27:1261-1267 (1988)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.191
IUBMB Enzyme Nomenclature: 2.4.1.191
ExPASy - ENZYME nomenclature database: 2.4.1.191
BRENDA, the Enzyme Database: 2.4.1.191
CAS: 115490-50-1
LinkDB

KEGG   REACTION: R06828
Entry
R06828                      Reaction                               

Name
UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase
Definition
Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + UDP-glucuronate <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + UDP
Equation
Comment
luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase
Reaction class
RC00005  C00015_C00167
RC00171  C04900_C12632
Enzyme
Pathway
rn00944  Flavone and flavonol biosynthesis
Other DBs
RHEA: 22119
LinkDB

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