KEGG   ENZYME: 2.4.1.242
Entry
EC 2.4.1.242                Enzyme                                 

Name
NDP-glucose---starch glucosyltransferase;
granule-bound starch synthase;
starch synthase II (ambiguous);
waxy protein;
starch granule-bound nucleoside diphosphate glucose-starch glucosyltransferase;
granule-bound starch synthase I;
GBSSI;
granule-bound starch synthase II;
GBSSII;
GBSS;
NDPglucose-starch glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
NDP-glucose:(1->4)-alpha-D-glucan 4-alpha-D-glucosyltransferase
Reaction(IUBMB)
NDP-glucose + [(1->4)-alpha-D-glucosyl]n = NDP + [(1->4)-alpha-D-glucosyl]n+1 [RN:R07261]
Reaction(KEGG)
R07261 > R00292 R02421 R06049(G) R06051(G)
Substrate
NDP-glucose [CPD:C15541];
[(1->4)-alpha-D-glucosyl]n
Product
NDP [CPD:C00454];
[(1->4)-alpha-D-glucosyl]n+1
Comment
Unlike EC 2.4.1.11, glycogen(starch) synthase and EC 2.4.1.21, starch synthase, which use UDP-glucose and ADP-glucose, respectively, this enzyme can use either UDP- or ADP-glucose. Mutants that lack the Wx (waxy) allele cannot produce this enzyme, which plays an important role in the normal synthesis of amylose. In such mutants, only amylopectin is produced in the endosperm [3] or pollen [5].
History
EC 2.4.1.242 created 2005
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K13679  granule-bound starch synthase
K20812  glycogen synthase
Genes
ATH: AT1G32900(GBSS1)
ALY: 9327077
CRB: 17898386
CSAT: 104741860 104757652 104779038
EUS: EUTSA_v10007089mg
BRP: 103874772
BNA: 111211457 111212542
BOE: 106295327
RSZ: 108863044
THJ: 104806459
CPAP: 110816544
TCC: 18605949
LJA: Lj3g3v2515230.1(Lj3g3v2515230.1) Lj5g3v1262950.2(Lj5g3v1262950.2)
PMUM: 103344039
CSV: 101208974
CMO: 103482870
MCHA: 111026058
SLY: 101259777(GBSS1)
SPEN: 107027917
SOT: 102577459(GBSS)
CANN: 107863475(waxy)
NTA: 107759522(GBSS1) 107829009(GBSSI)
NSY: 104222724
NTO: 104114157
NAU: 109237066
INI: 109157098(waxy)
SIND: 105164411
HAN: 110937495
LSV: 111911063
CCAV: 112503778
DCR: 108209256
NNU: 104593836(Waxy) 104604810
DOSA: Os06t0133000-01(Os06g0133000) Os07t0412100-01(Os07g0412100)
ATS: 109732118(LOC109732118) 109774163(LOC109774163)
ZMA: 100125638(GBSSIIa) 103630223 111589219 541854(wx1)
SITA: 101761090(WAXY) 101786779
PDA: 103695691
MUS: 103978866(GBSSI-2) 103996709 103998560(GBSSI-4)
DCT: 110099111
AOF: 109848515
ATR: 18428468
SMO: SELMODRAFT_149847(GBSS)
MNG: MNEG_7624
MIS: MICPUN_104736(GBSSI)
MPP: MICPUCDRAFT_49698(GBSSI)
SMIN: v1.2.010047.t1(symbB.v1.2.010047.t1) v1.2.010048.t1(symbB.v1.2.010048.t1) v1.2.021726.t1(symbB.v1.2.021726.t1) v1.2.021727.t1(symbB.v1.2.021727.t1)
GTT: GUITHDRAFT_164385(gbss)
PFU: PF2044
PFI: PFC_08345
PHO: PH0069(PH0069)
PAB: PAB2292
PYN: PNA2_0609
PYS: Py04_0144
TKO: TK1768
TON: TON_1798
TGA: TGAM_0597(glgA)
TSI: TSIB_1780
THE: GQS_06195
THA: TAM4_616
THM: CL1_0882
TLT: OCC_09339
THS: TES1_1656
TNU: BD01_1443
TEU: TEU_03535
PPAC: PAP_04985
TAG: Tagg_0641
 » show all
Reference
1  [PMID:4824506]
  Authors
Tsai CY.
  Title
The function of the waxy locus in starch synthesis in maize endosperm.
  Journal
Biochem Genet 11:83-96 (1974)
DOI:10.1007/bf00485766
Reference
2  [PMID:9765530]
  Authors
Nakamura T, Vrinten P, Hayakawa K, Ikeda J.
  Title
Characterization of a granule-bound starch synthase isoform found in the pericarp of wheat.
  Journal
Plant Physiol 118:451-9 (1998)
DOI:10.1104/pp.118.2.451
Reference
3  [PMID:9951718]
  Authors
Fujita N, Taira T.
  Title
A 56-kDa protein is a novel granule-bound starch synthase existing in the pericarps, aleurone layers, and embryos of immature seed in diploid wheat (Triticum monococcum L.).
  Journal
Planta 207:125-32 (1998)
DOI:10.1007/s004250050464
Reference
4  [PMID:10393240]
  Authors
Murai J, Taira T, Ohta D.
  Title
Isolation and characterization of the three Waxy genes encoding the granule-bound starch synthase in hexaploid wheat.
  Journal
Gene 234:71-9 (1999)
DOI:10.1016/S0378-1119(99)00178-X
Reference
5  [PMID:17248421]
  Authors
Nelson OE.
  Title
The WAXY Locus in Maize. II. the Location of the Controlling Element Alleles.
  Journal
Genetics 60:507-524 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.242
IUBMB Enzyme Nomenclature: 2.4.1.242
ExPASy - ENZYME nomenclature database: 2.4.1.242
BRENDA, the Enzyme Database: 2.4.1.242
CAS: 9031-53-2
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