KEGG   ENZYME: 2.8.1.5
Entry
EC 2.8.1.5                  Enzyme                                 

Name
thiosulfate---dithiol sulfurtransferase;
thiosulfate reductase;
TSR
Class
Transferases;
Transferring sulfur-containing groups;
Sulfurtransferases
Sysname
thiosulfate:dithioerythritol sulfurtransferase
Reaction(IUBMB)
thiosulfate + dithioerythritol = sulfite + 4,5-cis-dihydroxy-1,2-dithiacyclohexane (i.e. oxidized dithioerythritol) + sulfide [RN:R05072]
Reaction(KEGG)
R05072
Substrate
thiosulfate [CPD:C00320];
dithioerythritol [CPD:C00950]
Product
sulfite [CPD:C00094];
4,5-cis-dihydroxy-1,2-dithiacyclohexane [CPD:C06484];
sulfide [CPD:C00283]
Comment
The enzyme from Chlorella shows very little activity towards monothiols such as glutathione and cysteine (cf. EC 2.8.1.3 thiosulfate---thiolsulfurtransferase). The enzyme probably transfers the sulfur atom onto one thiol group to form -S-S-, and sulfide is spontaneously expelled from this by reaction with the other thiol group. May be identical with EC 2.8.1.1 thiosulfate sulfurtransferase.
History
EC 2.8.1.5 created 1989, modified 1999
Pathway
ec00920  Sulfur metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:24253096]
  Authors
Schmidt A, Erdle I, Gamon B
  Title
Isolation and characterization of thiosulfate reductases from the green alga Chlorella fusca.
  Journal
Planta 162:243-9 (1984)
DOI:10.1007/BF00397446
Other DBs
ExplorEnz - The Enzyme Database: 2.8.1.5
IUBMB Enzyme Nomenclature: 2.8.1.5
ExPASy - ENZYME nomenclature database: 2.8.1.5
BRENDA, the Enzyme Database: 2.8.1.5
CAS: 9059-49-8
LinkDB

KEGG   REACTION: R05072
Entry
R05072                      Reaction                               

Name
Thiosulfate:dithioerythritol sulfurtransferase
Definition
Thiosulfate + Dithioerythritol + H+ <=> Sulfite + Hydrogen sulfide + 4,5-cis-Dihydroxy-1,2-dithiacyclohexane
Equation
Reaction class
RC02813  C00094_C00320
RC02823  C00283_C00320
Enzyme
Pathway
rn00920  Sulfur metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Other DBs
RHEA: 15124
LinkDB

DBGET integrated database retrieval system