| Entry |
|
|---|
| Name |
Mitomycin (USP/INN);
Mitomycin C (JP17);
MMC;
Jelmyto (TN);
Mitomycin (TN);
Muamycin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C15H18N4O5
|
|---|
| Exact mass |
334.1277
|
|---|
| Mol weight |
334.3272
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Streptomyces caespitosus [TAX: 53502]
|
|---|
| Remark |
| Therapeutic category: | 4231 |
|
|---|
| Efficacy |
Antineoplastic |
|---|
| Disease |
Glaucoma [DS: H00612] Upper tract urothelial cancer [DS: H00022] Adenocarcinoma of the stomach or pancreas [DS: H00018 H00019] |
|---|
| Comment |
DNA synthesis inhibitor
|
|---|
| Target |
DNA |
|---|
| Interaction |
|
|---|
| Structure map |
| map07040 | Antineoplastics - alkylating agents |
| map07042 | Antineoplastics - agents from natural products |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
L01DC Other cytotoxic antibiotics
L01DC03 Mitomycin
D00208 Mitomycin (USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
423 Antibiotics
4231 Mytomycin C
D00208 Mitomycin (USP/INN); Mitomycin C (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00208 Mitomycin C
D00208 Mitomycin C for injection
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C1z C 26.7153 -18.5085
2 N1y N 25.8935 -19.6917
3 C1y C 28.0734 -18.9398
4 C1y C 25.8935 -17.3777
5 C2y C 24.5646 -19.2603
6 C1x C 26.7445 -20.7467
7 C1y C 28.0967 -20.3444
8 N1x N 29.3090 -19.6509
9 C2y C 24.5646 -17.8557
10 C1b C 26.3074 -16.0547
11 C5x C 23.3581 -19.9714
12 C5x C 23.3581 -17.1213
13 O7a O 25.3573 -15.0289
14 C2y C 22.1049 -19.2953
15 O5x O 23.3581 -21.3645
16 C2y C 22.0875 -17.8674
17 O5x O 23.3990 -15.7574
18 C7a C 25.7537 -13.6360
19 C1a C 20.8694 -20.0006
20 N1a N 20.8694 -17.1796
21 N1a N 27.1700 -13.3270
22 O6a O 24.8443 -12.5926
23 O2a O 27.4153 -17.2960
24 C1a C 28.8400 -16.6662
BOND 27
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 4 10 1 #Up
10 5 11 1
11 9 12 1
12 10 13 1
13 11 14 1
14 11 15 2
15 12 16 1
16 12 17 2
17 13 18 1
18 14 19 1
19 16 20 1
20 18 21 1
21 18 22 2
22 5 9 2
23 6 7 1
24 7 8 1
25 14 16 2
26 1 23 1 #Down
27 23 24 1
|
|---|
