KEGG   DRUG: BetamethasoneHelp
Entry
D00244                      Drug                                   

Name
Betamethasone (JP17/USP/INN);
Celestone (TN);
Rinderon (TN)
Formula
C22H29FO5
Exact mass
392.1999
Mol weight
392.4611
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
Same as: C06848
Therapeutic category: 2454
ATC code: A07EA04 C05AA05 D07AC01 D07XC01 H02AB01 R01AD06 R03BA04 S01BA06 S01CB04 S02BA07 S03BA03
Chemical structure group: DG00095
Product (DG00095): D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP>
Product (mixture): D04447<JP> D10300<US>
Efficacy
Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA04 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA05 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AC Corticosteroids, potent (group III)
     D07AC01 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XC Corticosteroids, potent, other combinations
     D07XC01 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB01 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD06 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA04 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA06 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB04 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA07 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03B CORTICOSTEROIDS
    S03BA Corticosteroids
     S03BA03 Betamethasone
      D00244  Betamethasone (JP17/USP/INN) <JP>
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatitis and Pruitus Agents
   Glucocorticoids, Medium Potency
    Betamethasone
     D00244  Betamethasone (JP17/USP/INN)
   Glucocorticoids, High Potency
    Betamethasone
     D00244  Betamethasone (JP17/USP/INN)
   Glucocorticoids, Very High Potency
    Betamethasone
     D00244  Betamethasone (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   245  Adrenal hormone preparations
    2454  Fluorinated adrenocorticotropic hormones
     D00244  Betamethasone (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D00244  Betamethasone (JP17/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00244  Betamethasone
  D00244  Betamethasone tablets
BRITE hierarchy
Other DBs
CAS: 378-44-9
PubChem: 7847310
ChEBI: 3077
ChEMBL: CHEMBL1377507 CHEMBL1610678 CHEMBL632
DrugBank: DB00443
LigandBox: D00244
NIKKAJI: J2.038I
LinkDB All DBs
KCF data Show

ATOM        28
            1   C2x C     6.7900  -14.9100
            2   C5x C     6.7900  -16.3100
            3   C2x C     8.0024  -17.0100
            4   C2y C     9.2149  -16.3100
            5   C1z C     9.2149  -14.9100
            6   C2x C     8.0024  -14.2100
            7   C1x C    10.4273  -17.0100
            8   C1x C    11.6397  -16.3100
            9   C1y C    11.6397  -14.9100
            10  C1z C    10.4273  -14.2100
            11  C1y C    12.8522  -14.2100
            12  C1z C    12.8522  -12.8100
            13  C1x C    11.6397  -12.1100
            14  C1y C    10.4273  -12.8100
            15  C1x C    15.2770  -14.2100
            16  C1y C    15.2770  -12.8100
            17  C1z C    14.0646  -12.1100
            18  C1a C     9.2149  -13.5100
            19  O1a O     9.2169  -12.1112
            20  C1a C    12.8522  -11.4100
            21  C1a C    16.4766  -12.1173
            22  C5a C    14.0646  -10.3600
            23  X   F    10.4273  -15.6100
            24  O1a O    15.2770  -11.4100
            25  O5x O     5.5776  -17.0100
            26  O5a O    15.2811   -9.6577
            27  C1b C    12.8562   -9.6623
            28  O1a O    11.6627  -10.3516
BOND        31
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    5  18 1 #Up
            22   14  19 1 #Up
            23   12  20 1 #Up
            24   16  21 1 #Up
            25   17  22 1 #Up
            26   10  23 1 #Down
            27   17  24 1 #Down
            28    2  25 2
            29   22  26 2
            30   22  27 1
            31   27  28 1

» Japanese version   » Back

KEGG   DRUG: Betamethasone sodium phosphateHelp
Entry
D00972                      Drug                                   

Name
Betamethasone sodium phosphate (JP17/USP);
Celestone (TN)
Formula
C22H28FO8P. 2Na
Exact mass
516.1301
Mol weight
516.4046
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
Therapeutic category: 1315 1329 2454
ATC code: A07EA04 C05AA05 D07AC01 D07XC01 H02AB01 R01AD06 R03BA04 S01BA06 S01CB04 S02BA07 S03BA03
Chemical structure group: DG00095
Product (DG00095): D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP>
Product (mixture): D04246<JP> D04446<JP/US>
Efficacy
Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA04 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA05 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AC Corticosteroids, potent (group III)
     D07AC01 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XC Corticosteroids, potent, other combinations
     D07XC01 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB01 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD06 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA04 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA06 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB04 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA07 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03B CORTICOSTEROIDS
    S03BA Corticosteroids
     S03BA03 Betamethasone
      D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatitis and Pruitus Agents
   Glucocorticoids, Medium Potency
    Betamethasone
     D00972  Betamethasone sodium phosphate (JP17/USP)
   Glucocorticoids, High Potency
    Betamethasone
     D00972  Betamethasone sodium phosphate (JP17/USP)
   Glucocorticoids, Very High Potency
    Betamethasone
     D00972  Betamethasone sodium phosphate (JP17/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1315  Ophthalmic cortisones
     D00972  Betamethasone sodium phosphate (JP17/USP)
   132  Otic and nasal agents
    1329  Others
     D00972  Betamethasone sodium phosphate (JP17/USP)
 2  Agents affecting individual organs
  24  Hormones
   245  Adrenal hormone preparations
    2454  Fluorinated adrenocorticotropic hormones
     D00972  Betamethasone sodium phosphate (JP17/USP)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D00972  Betamethasone sodium phosphate (JP17/USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00972  Betamethasone sodium phosphate
BRITE hierarchy
Other DBs
CAS: 151-73-5
PubChem: 7848035
ChEBI: 3078
ChEMBL: CHEMBL1200762
DrugBank: DB00443
LigandBox: D00972
NIKKAJI: J7.409H
LinkDB All DBs
KCF data Show

ATOM        34
            1   C1y C    20.5509  -18.6771
            2   C1y C    19.3622  -19.3588
            3   C1z C    20.5626  -17.2961
            4   C1x C    22.9399  -18.7004
            5   C1z C    18.1794  -18.6655
            6   C1x C    19.3622  -20.7281
            7   C1z C    21.7686  -16.6144
            8   C1x C    19.3855  -16.6144
            9   C1a C    20.5567  -15.9269
            10  C1y C    22.9514  -17.3253
            11  C1z C    16.9908  -19.3471
            12  C1y C    18.1910  -17.2961
            13  X   F    18.1677  -20.0289
            14  C1x C    18.1677  -21.4098
            15  C5a C    21.7745  -15.2451
            16  O1a O    23.0913  -16.2589
            17  C1a C    24.2741  -17.2381
            18  C2y C    16.9849  -20.7222
            19  C2x C    15.8021  -18.6596
            20  C1a C    16.9791  -17.9662
            21  O1a O    17.0025  -16.6028
            22  C1b C    22.9573  -14.5575
            23  O5a O    20.5743  -14.5575
            24  C2x C    15.8021  -21.4040
            25  C2x C    14.6135  -19.3471
            26  O2b O    24.1401  -15.2334
            27  C5x C    14.6135  -20.7222
            28  P1b P    25.2763  -14.4585
            29  O5x O    13.4190  -21.3981
            30  O1c O    26.4534  -15.1461
            31  O1c O    26.4068  -13.6836 #-
            32  O1c O    24.5014  -13.3223 #-
            33  Z   Na   28.9880  -14.9538 #+
            34  Z   Na   28.9181  -18.1935 #+
BOND        35
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     3   9 1 #Up
            9     4  10 1
            10    5  11 1
            11    5  12 1
            12    5  13 1 #Down
            13    6  14 1
            14    7  15 1 #Up
            15    7  16 1 #Down
            16   10  17 1 #Up
            17   11  18 1
            18   11  19 1
            19   11  20 1 #Up
            20   12  21 1 #Up
            21   15  22 1
            22   15  23 2
            23   18  24 2
            24   19  25 2
            25   22  26 1
            26   24  27 1
            27   26  28 1
            28   27  29 2
            29   28  30 2
            30   28  31 1
            31   28  32 1
            32    7  10 1
            33    8  12 1
            34   14  18 1
            35   25  27 1

» Japanese version   » Back

KEGG   DRUG: Betamethasone valerateHelp
Entry
D01357                      Drug                                   

Name
Betamethasone valerate (JP17/USP);
Beta-Val (TN);
Luxiq (TN);
Rinderon-V (TN)
Product
  Generic
Formula
C27H37FO6
Exact mass
476.2574
Mol weight
476.5775
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
Therapeutic category: 2646
ATC code: A07EA04 C05AA05 D07AC01 D07XC01 H02AB01 R01AD06 R03BA04 S01BA06 S01CB04 S02BA07 S03BA03
Chemical structure group: DG00095
Product (DG00095): D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP>
Product (mixture): D04773<JP> D04796<JP>
Efficacy
Anti-inflammatory, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA04 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA05 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AC Corticosteroids, potent (group III)
     D07AC01 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XC Corticosteroids, potent, other combinations
     D07XC01 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB01 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD06 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA04 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA06 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB04 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA07 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03B CORTICOSTEROIDS
    S03BA Corticosteroids
     S03BA03 Betamethasone
      D01357  Betamethasone valerate (JP17/USP) <JP/US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatitis and Pruitus Agents
   Glucocorticoids, Medium Potency
    Betamethasone
     D01357  Betamethasone valerate (JP17/USP)
   Glucocorticoids, High Potency
    Betamethasone
     D01357  Betamethasone valerate (JP17/USP)
   Glucocorticoids, Very High Potency
    Betamethasone
     D01357  Betamethasone valerate (JP17/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   264  Analgesics, anti-itchings, astringents, anti-inflammatory agents
    2646  Adrenocorticotropic hormones
     D01357  Betamethasone valerate (JP17/USP)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  56 Purulent skin remedies
   D01357  Betamethasone valerate (JP17/USP)
  57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
   D01357  Betamethasone valerate (JP17/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Betamethasone valerate
    D01357  Betamethasone valerate (JP17/USP)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Betamethasone valerate
    D01357  Betamethasone valerate (JP17/USP)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D01357  Betamethasone valerate (JP17/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01357  Betamethasone valerate
Topical steroids potency [br08317.html]
 Classification in Japan
  D01357
BRITE hierarchy
Other DBs
CAS: 2152-44-5
PubChem: 7848420
ChEBI: 31277
ChEMBL: CHEMBL1497
DrugBank: DB00443
LigandBox: D01357
NIKKAJI: J7.337G
LinkDB All DBs
KCF data Show

ATOM        34
            1   C2x C     5.4764  -10.5555
            2   C5x C     5.4764  -11.9007
            3   C2x C     6.6413  -12.5733
            4   C2y C     7.8063  -11.9007
            5   C1z C     7.8063  -10.5555
            6   C2x C     6.6413   -9.8830
            7   C1x C     8.9713  -12.5733
            8   C1x C    10.1362  -11.9007
            9   C1y C    10.1362  -10.5555
            10  C1z C     8.9713   -9.8830
            11  C1y C    11.3011   -9.8830
            12  C1z C    11.3011   -8.5378
            13  C1x C    10.1362   -7.8652
            14  C1y C     8.9713   -8.5378
            15  C1x C    13.6310   -9.8830
            16  C1y C    13.6310   -8.5378
            17  C1z C    12.4661   -7.8652
            18  C1a C     7.8063   -9.2103
            19  O1a O     7.8083   -7.8664
            20  C1a C    11.3011   -7.1927
            21  C1a C    14.7836   -7.8722
            22  C5a C    12.4661   -6.1138
            23  X   F     8.9713  -11.2281
            24  O7a O    14.2538   -6.7775
            25  O5x O     4.3116  -12.5733
            26  O5a O    13.6350   -5.4390
            27  C1b C    11.3050   -5.4434
            28  C7a C    15.6379   -6.7775
            29  O6a O    16.3156   -7.9508
            30  C1b C    16.3407   -5.5606
            31  C1b C    17.7063   -5.5610
            32  O1a O    10.0592   -6.1628
            33  C1b C    18.4212   -4.3241
            34  C1a C    19.8099   -4.3249
BOND        37
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    5  18 1 #Up
            22   14  19 1 #Up
            23   12  20 1 #Up
            24   16  21 1 #Up
            25   17  22 1 #Up
            26   10  23 1 #Down
            27   17  24 1 #Down
            28    2  25 2
            29   22  26 2
            30   22  27 1
            31   24  28 1
            32   28  29 2
            33   28  30 1
            34   30  31 1
            35   27  32 1
            36   31  33 1
            37   33  34 1

» Japanese version   » Back

KEGG   DRUG: Betamethasone acetateHelp
Entry
D01402                      Drug                                   

Name
Betamethasone acetate (JAN/USP)
Formula
C24H31FO6
Exact mass
434.2105
Mol weight
434.4977
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
ATC code: A07EA04 C05AA05 D07AC01 D07XC01 H02AB01 R01AD06 R03BA04 S01BA06 S01CB04 S02BA07 S03BA03
Chemical structure group: DG00095
Product (DG00095): D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP>
Product (mixture): D04446<JP/US>
Efficacy
Anti-inflammatory, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA04 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA05 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AC Corticosteroids, potent (group III)
     D07AC01 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XC Corticosteroids, potent, other combinations
     D07XC01 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB01 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD06 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA04 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA06 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB04 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA07 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03B CORTICOSTEROIDS
    S03BA Corticosteroids
     S03BA03 Betamethasone
      D01402  Betamethasone acetate (JAN/USP)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D01402  Betamethasone acetate (JAN/USP)
BRITE hierarchy
Other DBs
CAS: 987-24-6
PubChem: 7848465
ChEBI: 31275
ChEMBL: CHEMBL1200538
DrugBank: DB00443
LigandBox: D01402
NIKKAJI: J7.211G
LinkDB All DBs
KCF data Show

ATOM        31
            1   C2x C    23.2592  -19.7410
            2   C5x C    23.2592  -21.1017
            3   C2x C    24.4375  -21.7820
            4   C2y C    25.6159  -21.1017
            5   C1z C    25.6159  -19.7410
            6   C2x C    24.4375  -19.0607
            7   C1x C    26.7943  -21.7820
            8   C1x C    27.9726  -21.1017
            9   C1y C    27.9726  -19.7410
            10  C1z C    26.7943  -19.0607
            11  C1y C    29.1510  -19.0607
            12  C1z C    29.1510  -17.7000
            13  C1x C    27.9726  -17.0197
            14  C1y C    26.7943  -17.7000
            15  C1x C    31.5077  -19.0607
            16  C1y C    31.5077  -17.7000
            17  C1z C    30.3294  -17.0197
            18  C1a C    25.6159  -18.3803
            19  O1a O    25.6179  -17.0209
            20  C1a C    29.1510  -16.3394
            21  C1a C    32.6736  -17.0268
            22  C5a C    30.3294  -15.3189
            23  X   F    26.7943  -20.4213
            24  O1a O    31.5077  -16.1294
            25  O5x O    22.0809  -21.7820
            26  O5a O    31.5117  -14.6363
            27  C1b C    29.1549  -14.6408
            28  O7a O    27.9950  -15.3107
            29  C7a C    26.7945  -14.6180
            30  C1a C    25.5888  -15.3147
            31  O6a O    26.7943  -13.2301
BOND        34
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    5  18 1 #Up
            22   14  19 1 #Up
            23   12  20 1 #Up
            24   16  21 1 #Up
            25   17  22 1 #Up
            26   10  23 1 #Down
            27   17  24 1 #Down
            28    2  25 2
            29   22  26 2
            30   22  27 1
            31   27  28 1
            32   28  29 1
            33   29  30 1
            34   29  31 2

» Japanese version   » Back

KEGG   DRUG: Betamethasone dipropionateHelp
Entry
D01637                      Drug                                   

Name
Betamethasone dipropionate (JP17/USP);
Diprolene (TN);
Rinderon-DP (TN);
Sernivo (TN)
Product
  Generic
BETAMETHASONE DIPROPIONATE (A-S Medication Solutions), BETAMETHASONE DIPROPIONATE (A-S Medication Solutions), BETAMETHASONE DIPROPIONATE (A-S Medication Solutions), BETAMETHASONE DIPROPIONATE (A-S Medication Solutions), BETAMETHASONE DIPROPIONATE (A-S Medication Solutions), BETAMETHASONE DIPROPIONATE (A-S Medication Solutions), BETAMETHASONE DIPROPIONATE (Actavis Pharma), BETAMETHASONE DIPROPIONATE (Actavis Pharma), BETAMETHASONE DIPROPIONATE (Actavis Pharma), BETAMETHASONE DIPROPIONATE (Cadila Healthcare Limited), BETAMETHASONE DIPROPIONATE (Cosette Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Cosette Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Cosette Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Cosette Pharmaceuticals), BETAMETHASONE DIPROPIONATE (E. Fougera & Co. a division of Fougera Pharmaceuticals), BETAMETHASONE DIPROPIONATE (E. Fougera & Co. a division of Fougera Pharmaceuticals), BETAMETHASONE DIPROPIONATE (E. Fougera & Co. a division of Fougera Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Glenmark Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Golden State Medical Supply), BETAMETHASONE DIPROPIONATE (H.J. Harkins Company), BETAMETHASONE DIPROPIONATE (Lupin Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Northstar Rx LLC.), BETAMETHASONE DIPROPIONATE (NuCare Pharmaceuticals), BETAMETHASONE DIPROPIONATE (NuCare Pharmaceuticals), BETAMETHASONE DIPROPIONATE (NuCare Pharmaceuticals), BETAMETHASONE DIPROPIONATE (NuCare Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Perrigo New York), BETAMETHASONE DIPROPIONATE (Perrigo New York), BETAMETHASONE DIPROPIONATE (Prasco Laboratories), BETAMETHASONE DIPROPIONATE (Preferred Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Preferred Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Preferred Pharmaceuticals), BETAMETHASONE DIPROPIONATE (Proficient Rx LP), BETAMETHASONE DIPROPIONATE (Proficient Rx LP), BETAMETHASONE DIPROPIONATE (Taro Pharmaceuticals U.S.A.), BETAMETHASONE DIPROPIONATE (Taro Pharmaceuticals U.S.A.), BETAMETHASONE DIPROPIONATE (Taro Pharmaceuticals U.S.A.), BETAMETHASONE DIPROPIONATE (Taro Pharmaceuticals U.S.A.), BETAMETHASONE DIPROPIONATE (Taro Pharmaceuticals U.S.A.), BETAMETHASONE DIPROPIONATE (Teligent Pharma), BETAMETHASONE DIPROPIONATE (Teligent Pharma), BETAMETHASONE DIPROPIONATE (VersaPharm Inc. - An Akorn Company), BETAMETHASONE DIPROPIONATE (VersaPharm), BETAMETHASONE DIPROPIONATE (Zydus Pharmaceuticals (USA))
Formula
C28H37FO7
Exact mass
504.2523
Mol weight
504.5876
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
Therapeutic category: 2646
ATC code: A07EA04 C05AA05 D07AC01 D07XC01 H02AB01 R01AD06 R03BA04 S01BA06 S01CB04 S02BA07 S03BA03
Chemical structure group: DG00095
Product (DG00095): D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP>
Product (mixture): D10300<US> D10534<JP/US>
Efficacy
Anti-inflammatory, Antipruritic, Glucocorticoid receptor agonist
  Disease
Plaque psoriasis [DS:H01656]
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA04 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA05 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AC Corticosteroids, potent (group III)
     D07AC01 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XC Corticosteroids, potent, other combinations
     D07XC01 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB01 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD06 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA04 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA06 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB04 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA07 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03B CORTICOSTEROIDS
    S03BA Corticosteroids
     S03BA03 Betamethasone
      D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatitis and Pruitus Agents
   Glucocorticoids, Medium Potency
    Betamethasone
     D01637  Betamethasone dipropionate (JP17/USP)
   Glucocorticoids, High Potency
    Betamethasone
     D01637  Betamethasone dipropionate (JP17/USP)
   Glucocorticoids, Very High Potency
    Betamethasone
     D01637  Betamethasone dipropionate (JP17/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   264  Analgesics, anti-itchings, astringents, anti-inflammatory agents
    2646  Adrenocorticotropic hormones
     D01637  Betamethasone dipropionate (JP17/USP)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D01637  Betamethasone dipropionate (JP17/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01637  Betamethasone dipropionate
Topical steroids potency [br08317.html]
 Classification in the USA
  D01637
 Classification in Japan
  D01637
BRITE hierarchy
Other DBs
CAS: 5593-20-4
PubChem: 7848700
ChEBI: 31276
ChEMBL: CHEMBL1200384
DrugBank: DB00443
LigandBox: D01637
NIKKAJI: J8.022E
LinkDB All DBs
KCF data Show

ATOM        36
            1   C2x C     6.3892  -13.6510
            2   C5x C     6.3892  -15.0117
            3   C2x C     7.5675  -15.6920
            4   C2y C     8.7459  -15.0117
            5   C1z C     8.7459  -13.6510
            6   C2x C     7.5675  -12.9707
            7   C1x C     9.9243  -15.6920
            8   C1x C    11.1026  -15.0117
            9   C1y C    11.1026  -13.6510
            10  C1z C     9.9243  -12.9707
            11  C1y C    12.2810  -12.9707
            12  C1z C    12.2810  -11.6100
            13  C1x C    11.1026  -10.9297
            14  C1y C     9.9243  -11.6100
            15  C1x C    14.6377  -12.9707
            16  C1y C    14.6377  -11.6100
            17  C1z C    13.4594  -10.9297
            18  C1a C     8.7459  -12.2903
            19  O1a O     8.7479  -10.9309
            20  C1a C    12.2810  -10.2494
            21  C1a C    15.8036  -10.9368
            22  C5a C    13.4594   -9.2289
            23  X   F     9.9243  -14.3313
            24  O7a O    15.2677   -9.8294
            25  O5x O     5.2109  -15.6920
            26  O5a O    14.6417   -8.5463
            27  C1b C    12.2849   -8.5508
            28  O7a O    11.1250   -9.2207
            29  C7a C     9.9245   -8.5280
            30  C1b C     8.7188   -9.2247
            31  C1a C     7.5362   -8.5423
            32  O6a O     9.9243   -7.1401
            33  C7a C    16.6677   -9.8294
            34  O6a O    17.3532  -11.0163
            35  C1b C    17.3786   -8.5985
            36  C1a C    18.7600   -8.5989
BOND        39
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    5  18 1 #Up
            22   14  19 1 #Up
            23   12  20 1 #Up
            24   16  21 1 #Up
            25   17  22 1 #Up
            26   10  23 1 #Down
            27   17  24 1 #Down
            28    2  25 2
            29   22  26 2
            30   22  27 1
            31   27  28 1
            32   28  29 1
            33   29  30 1
            34   30  31 1
            35   29  32 2
            36   24  33 1
            37   33  34 2
            38   33  35 1
            39   35  36 1

» Japanese version   » Back

KEGG   DRUG: Betamethasone butyrate propionateHelp
Entry
D02032                      Drug                                   

Name
Betamethasone butyrate propionate (JAN);
Antebate (TN)
Formula
C29H39FO7
Exact mass
518.268
Mol weight
518.6142
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
Therapeutic category: 2646
ATC code: A07EA04 C05AA05 D07AC01 D07XC01 H02AB01 R01AD06 R03BA04 S01BA06 S01CB04 S02BA07 S03BA03
Chemical structure group: DG00095
Product (DG00095): D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP>
Product (mixture): D10788<JP>
Efficacy
Anti-inflammatory, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA04 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA05 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AC Corticosteroids, potent (group III)
     D07AC01 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XC Corticosteroids, potent, other combinations
     D07XC01 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB01 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD06 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA04 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA06 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB04 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA07 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03B CORTICOSTEROIDS
    S03BA Corticosteroids
     S03BA03 Betamethasone
      D02032  Betamethasone butyrate propionate (JAN) <JP>
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatitis and Pruitus Agents
   Glucocorticoids, Medium Potency
    Betamethasone
     D02032  Betamethasone butyrate propionate (JAN)
   Glucocorticoids, High Potency
    Betamethasone
     D02032  Betamethasone butyrate propionate (JAN)
   Glucocorticoids, Very High Potency
    Betamethasone
     D02032  Betamethasone butyrate propionate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   264  Analgesics, anti-itchings, astringents, anti-inflammatory agents
    2646  Adrenocorticotropic hormones
     D02032  Betamethasone butyrate propionate (JAN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D02032  Betamethasone butyrate propionate (JAN) <JP>
Topical steroids potency [br08317.html]
 Classification in Japan
  D02032
BRITE hierarchy
Other DBs
CAS: 5534-02-1
PubChem: 7849094
ChEMBL: CHEMBL1697785
DrugBank: DB00443
LigandBox: D02032
NIKKAJI: J277.648K
LinkDB All DBs
KCF data Show

ATOM        37
            1   C2x C    15.6561  -19.4690
            2   C5x C    15.6561  -20.8194
            3   C2x C    16.8256  -21.4948
            4   C2y C    17.9952  -20.8194
            5   C1z C    17.9952  -19.4690
            6   C2x C    16.8256  -18.7937
            7   C1x C    19.1647  -21.4948
            8   C1x C    20.3344  -20.8194
            9   C1y C    20.3344  -19.4690
            10  C1z C    19.1647  -18.7937
            11  C1y C    21.5039  -18.7937
            12  C1z C    21.5039  -17.4432
            13  C1x C    20.3344  -16.7679
            14  C1y C    19.1647  -17.4432
            15  C1x C    23.8430  -18.7937
            16  C1y C    23.8430  -17.4432
            17  C1z C    22.6735  -16.7679
            18  C1a C    25.2197  -17.4517
            19  C5a C    22.6737  -15.0019
            20  C1a C    21.4866  -16.0984
            21  O1a O    17.9476  -16.7404
            22  C1a C    17.9831  -18.0546
            23  O5x O    14.4453  -21.5185
            24  X   F    19.1493  -20.2006
            25  O7a O    23.9078  -16.0487
            26  O5a O    23.9029  -14.2923
            27  C1b C    21.4828  -14.2991
            28  O7a O    20.2708  -14.9989
            29  C7a C    19.0588  -14.2991
            30  C1b C    17.8467  -14.9989
            31  O6a O    19.0588  -12.8996
            32  C1a C    16.6320  -14.2975
            33  C7a C    26.0073  -16.0487
            34  O6a O    26.7103  -17.2661
            35  C1b C    26.6970  -14.8538
            36  C1b C    28.0922  -14.8536
            37  C1a C    28.7947  -13.6363
BOND        40
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21   16  18 1 #Up
            22   17  19 1 #Up
            23   12  20 1 #Up
            24   14  21 1 #Up
            25    5  22 1 #Up
            26    2  23 2
            27   10  24 1 #Down
            28   17  25 1 #Down
            29   19  26 2
            30   19  27 1
            31   27  28 1
            32   28  29 1
            33   29  30 1
            34   29  31 2
            35   30  32 1
            36   25  33 1
            37   33  34 2
            38   33  35 1
            39   35  36 1
            40   36  37 1

» Japanese version   » Back

KEGG   DRUG: Betamethasone benzoateHelp
Entry
D02286                      Drug                                   

Name
Betamethasone benzoate (USP);
Uticort (TN)
Formula
C29H33FO6
Exact mass
496.2261
Mol weight
496.5671
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
ATC code: A07EA04 C05AA05 D07AC01 D07XC01 H02AB01 R01AD06 R03BA04 S01BA06 S01CB04 S02BA07 S03BA03
Chemical structure group: DG00095
Product (DG00095): D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP>
Efficacy
Anti-inflammatory, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA04 Betamethasone
      D02286  Betamethasone benzoate (USP)
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA05 Betamethasone
      D02286  Betamethasone benzoate (USP)
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AC Corticosteroids, potent (group III)
     D07AC01 Betamethasone
      D02286  Betamethasone benzoate (USP)
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XC Corticosteroids, potent, other combinations
     D07XC01 Betamethasone
      D02286  Betamethasone benzoate (USP)
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB01 Betamethasone
      D02286  Betamethasone benzoate (USP)
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD06 Betamethasone
      D02286  Betamethasone benzoate (USP)
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA04 Betamethasone
      D02286  Betamethasone benzoate (USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA06 Betamethasone
      D02286  Betamethasone benzoate (USP)
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB04 Betamethasone
      D02286  Betamethasone benzoate (USP)
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA07 Betamethasone
      D02286  Betamethasone benzoate (USP)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03B CORTICOSTEROIDS
    S03BA Corticosteroids
     S03BA03 Betamethasone
      D02286  Betamethasone benzoate (USP)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D02286  Betamethasone benzoate (USP)
BRITE hierarchy
Other DBs
CAS: 22298-29-9
PubChem: 7849345
ChEMBL: CHEMBL1200376
DrugBank: DB00443
LigandBox: D02286
NIKKAJI: J11.413H
LinkDB All DBs
KCF data Show

ATOM        36
            1   C2x C    15.5339  -19.8143
            2   C5x C    15.5339  -21.1939
            3   C2x C    16.7287  -21.8837
            4   C2y C    17.9235  -21.1939
            5   C1z C    17.9235  -19.8143
            6   C2x C    16.7287  -19.1245
            7   C1x C    19.1182  -21.8837
            8   C1x C    20.3130  -21.1939
            9   C1y C    20.3130  -19.8143
            10  C1z C    19.1182  -19.1245
            11  C1y C    21.5077  -19.1245
            12  C1z C    21.5077  -17.7449
            13  C1x C    20.3130  -17.0551
            14  C1y C    19.1182  -17.7449
            15  C1x C    23.8973  -19.1245
            16  C1y C    23.8973  -17.7449
            17  C1z C    22.7024  -17.0551
            18  O5x O    14.3392  -21.8837
            19  C1a C    17.9252  -18.4347
            20  C1a C    21.5122  -16.3653
            21  C1a C    25.0047  -17.2364
            22  X   F    19.1208  -20.5041
            23  O1a O    17.9254  -17.0562
            24  C5a C    22.7078  -15.3256
            25  C1b C    21.5157  -14.6311
            26  O5a O    23.9052  -14.6403
            27  O1a O    20.3137  -15.3189
            28  O7a O    23.9035  -16.3653
            29  C7a C    25.6330  -16.3653
            30  O6a O    26.3228  -17.5601
            31  C8y C    26.3228  -15.1705
            32  C8x C    27.7024  -15.1705
            33  C8x C    28.3922  -13.9758
            34  C8x C    27.7024  -12.7811
            35  C8x C    26.3228  -12.7811
            36  C8x C    25.6330  -13.9758
BOND        40
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    2  18 2
            22    5  19 1 #Up
            23   12  20 1 #Up
            24   16  21 1 #Up
            25   10  22 1 #Down
            26   14  23 1 #Up
            27   17  24 1 #Up
            28   24  25 1
            29   24  26 2
            30   25  27 1
            31   17  28 1 #Down
            32   28  29 1
            33   29  30 2
            34   29  31 1
            35   31  32 2
            36   32  33 1
            37   33  34 2
            38   34  35 1
            39   35  36 2
            40   31  36 1

» Japanese version   » Back

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