| Entry |
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| Name |
Carbamazepine (JP17/USP/INN);
Equetro (TN);
Tegretol (TN) |
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| Product |
|
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| Generic |
CARBAMAZEPINE (A-S Medication Solutions), CARBAMAZEPINE (ATLANTIC BIOLOGICALS CORP.), CARBAMAZEPINE (ATLANTIC BIOLOGICALS CORP.), CARBAMAZEPINE (American Health Packaging), CARBAMAZEPINE (American Health Packaging), CARBAMAZEPINE (American Health Packaging), CARBAMAZEPINE (American Health Packaging), CARBAMAZEPINE (Aphena Pharma Solutions - Tennessee), CARBAMAZEPINE (Aphena Pharma Solutions - Tennessee), CARBAMAZEPINE (Apotex Corp.), CARBAMAZEPINE (Apotex Corp.), CARBAMAZEPINE (Bryant Ranch Prepack), CARBAMAZEPINE (Bryant Ranch Prepack), CARBAMAZEPINE (Bryant Ranch Prepack), CARBAMAZEPINE (Bryant Ranch Prepack), CARBAMAZEPINE (Bryant Ranch Prepack), CARBAMAZEPINE (Cadila Healthcare Limited), CARBAMAZEPINE (Cardinal Health), CARBAMAZEPINE (Clinical Solutions Wholesale), CARBAMAZEPINE (Contract Pharmacy Services-PA), CARBAMAZEPINE (Contract Pharmacy Services-PA), CARBAMAZEPINE (Golden State Medical Supply), CARBAMAZEPINE (Golden State Medical Supply), CARBAMAZEPINE (Golden State Medical Supply), CARBAMAZEPINE (Major Pharmaceuticals), CARBAMAZEPINE (Morton Grove Pharmaceuticals), CARBAMAZEPINE (Mylan Institutional), CARBAMAZEPINE (NCS HealthCare of KY), CARBAMAZEPINE (NCS HealthCare of KY), CARBAMAZEPINE (NIVAGEN PHARMACEUTICALS), CARBAMAZEPINE (Nostrum Laboratories), CARBAMAZEPINE (NuCare Pharmaceuticals), CARBAMAZEPINE (NuCare Pharmaceuticals), CARBAMAZEPINE (PD-Rx Pharmaceuticals), CARBAMAZEPINE (Pharmaceutical Associates), CARBAMAZEPINE (Prasco Laboratories), CARBAMAZEPINE (Precision Dose), CARBAMAZEPINE (Preferred Pharmaceuticals), CARBAMAZEPINE (Proficient Rx LP), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (REMEDYREPACK), CARBAMAZEPINE (RedPharm Drug), CARBAMAZEPINE (Rising Pharma Holdings), CARBAMAZEPINE (Sandoz), CARBAMAZEPINE (Taro Pharmaceuticals U.S.A.), CARBAMAZEPINE (Taro Pharmaceuticals U.S.A.), EPITOL (Teva Pharmaceuticals USA), CARBAMAZEPINE (Teva Pharmaceuticals USA), CARBAMAZEPINE (Torrent Pharmaceuticals Limited), CARBAMAZEPINE (Zydus Pharmaceuticals (USA)), CARBAMAZEPINE (direct rx) |
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| Formula |
C15H12N2O
|
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| Exact mass |
236.095
|
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| Mol weight |
236.2686
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG02034 Carboxamide antiepileptics
Metabolizing enzyme substrate
DG02913 CYP3A4 substrate
Metabolizing enzyme inducer
DG01635 CYP3A4 inducer
Transporter inducer
DG01893 ABCB1 (P-GP) inducer
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| Remark |
|
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| Efficacy |
Analgesic, Antiepileptic |
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| Disease |
Trigeminal neuralgia [DS: H01638] |
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| Comment |
Carboxamide derivative
|
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| Target |
|
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| Pathway |
|
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
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| Interaction |
CYP induction: CYP3A4 [HSA: 1576]
Transporter induction: ABCB1 [HSA: 5243]
|
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| Structure map |
|
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| Other map |
| map00982 | Drug metabolism - cytochrome P450 |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N03 ANTIEPILEPTICS
N03A ANTIEPILEPTICS
N03AF Carboxamide derivatives
N03AF01 Carbamazepine
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Anticonvulsants
Sodium Channel Agents
Carbamazepine
D00252 Carbamazepine (JP17/USP/INN)
Bipolar Agents
Mood Stabilizers
Carbamazepine
D00252 Carbamazepine (JP17/USP/INN)
Central Nervous System Agents
Central Nervous System, Other
Carbamazepine
D00252 Carbamazepine (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
113 Antiepileptics
1139 Others
D00252 Carbamazepine (JP17/USP/INN)
117 Psychotropics
1179 Others
D00252 Carbamazepine (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
SCN2A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
SCN3A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
SCN4A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
SCN5A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
SCN8A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
SCN9A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
SCN10A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
SCN11A
D00252 Carbamazepine (JP17/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00252 Carbamazepine
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00252
Drug transporters
D00252
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00252
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 18
1 C8y C 25.8138 -16.0918
2 N1y N 27.0678 -15.4768
3 C8y C 28.3384 -16.0677
4 C8y C 28.6645 -17.4200
5 C8y C 25.5184 -17.4703
6 C2x C 27.8109 -18.5337
7 C2x C 26.4089 -18.5521
8 C8x C 24.7745 -15.1529
9 C8x C 23.4416 -15.5834
10 C8x C 23.1462 -16.9619
11 C8x C 24.1856 -17.9009
12 C8x C 30.0176 -17.7825
13 C8x C 31.0080 -16.7920
14 C8x C 30.6455 -15.4389
15 C8x C 29.2925 -15.0764
16 C5a C 27.1234 -14.0772
17 O5a O 25.8856 -13.3793
18 N1a N 28.3126 -13.3740
BOND 20
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 2
8 1 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 5 11 2
13 4 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 15 3 2
18 2 16 1
19 16 17 2
20 16 18 1
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