| Entry |
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| Name |
Diazepam (JP17/USP/INN);
Diastat (TN);
Valium (TN)
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| Product |
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| Generic |
DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (A-S Medication Solutions), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Aphena Pharma Solutions - Tennessee), DIAZEPAM (Bryant Ranch Prepack), DIAZEPAM (Bryant Ranch Prepack), DIAZEPAM (Bryant Ranch Prepack), DIAZEPAM (Bryant Ranch Prepack), DIAZEPAM (Cardinal Health), DIAZEPAM (Cardinal Health), DIAZEPAM (Cardinal Health), DIAZEPAM (Civica), DIAZEPAM (Clinical Solutions Wholesale), DIAZEPAM (Clinical Solutions Wholesale), DIAZEPAM (Clinical Solutions Wholesale), DIAZEPAM (Clinical Solutions Wholesale), DIAZEPAM (Contract Pharmacy Services-PA), DIAZEPAM (Contract Pharmacy Services-PA), DIAZEPAM (DIRECT RX), DIAZEPAM (Dash Pharmaceuticals LLC), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (Direct_Rx), DIAZEPAM (General Injectables and Vaccines), DIAZEPAM (General Injectables and Vaccines), DIAZEPAM (Hospira), DIAZEPAM (Hospira), DIAZEPAM (Hospira), DIAZEPAM (Lake Erie Medical DBA Quality Care Products LLC), DIAZEPAM (Lake Erie Medical DBA Quality Care Products LLC), DIAZEPAM (Lannett Company), DIAZEPAM (Major Pharmaceuticals), DIAZEPAM (Mayne Pharma), DIAZEPAM (McKesson Corporation dba SKY Packaging), DIAZEPAM (Medsource Pharmaceuticals), DIAZEPAM (Medsource Pharmaceuticals), DIAZEPAM (Mylan Institutional), DIAZEPAM (Mylan Pharmaceuticals), DIAZEPAM (NCS HealthCare of KY), DIAZEPAM (NCS HealthCare of KY), DIAZEPAM (NCS HealthCare of KY), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (NuCare Pharmaceuticals), DIAZEPAM (Oceanside Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (PD-Rx Pharmaceuticals), DIAZEPAM (Precision Dose), DIAZEPAM (Preferred Pharmaceuticals), DIAZEPAM (Preferred Pharmaceuticals), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Proficient Rx LP), DIAZEPAM (Proficient Rx LP), DIAZEPAM (REMEDYREPACK), DIAZEPAM (REMEDYREPACK), DIAZEPAM (REMEDYREPACK), DIAZEPAM (REMEDYREPACK), DIAZEPAM (REMEDYREPACK), DIAZEPAM (REMEDYREPACK), DIAZEPAM (RedPharm Drug), DIAZEPAM (RedPharm Drug), DIAZEPAM (Redpharm Drug), DIAZEPAM (St Mary's Medical Park Pharmacy), DIAZEPAM (St. Mary's Medical Park Pharmacy), DIAZEPAM (Teva Pharmaceuticals USA), DIAZEPAM (Teva Pharmaceuticals USA), DIAZEPAM (Unit Dose Services), DIAZEPAM INTENSOL (West-Ward Pharmaceuticals Corp.) |
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| Formula |
C16H13ClN2O
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| Exact mass |
284.0716
|
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| Mol weight |
284.7402
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| Structure |
   |
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| Simcomp |
 |
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| Class |
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG01914 Anxiolytics, benzodiazepine derivatives
Metabolizing enzyme substrate
DG01639 CYP2C19 substrate
DG02913 CYP3A4 substrate
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| Remark |
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| Efficacy |
Antianxiety, Minor tranquilizer, Sedative-hypnotic |
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| Disease |
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| Comment |
Benzodiazepine derivative
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Metabolism |
Enzyme: CYP2C19 [HSA: 1557], CYP3A4 [HSA: 1576]
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| Interaction |
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| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05B ANXIOLYTICS
N05BA Benzodiazepine derivatives
N05BA01 Diazepam
D00293 Diazepam (JP17/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Anticonvulsants
Gamma-aminobutyric Acid (GABA) Augmenting Agents
Benzodiazepines
Diazepam
D00293 Diazepam (JP17/USP/INN)
Anxiolytics
Benzodiazepines
Diazepam
D00293 Diazepam (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1124 Benzodiazepins
D00293 Diazepam (JP17/USP/INN)
113 Antiepileptics
1139 Others
D00293 Diazepam (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00293 Diazepam (JP17/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00293 Diazepam
D00293 Diazepam tablets
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00293
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 20
1 C2y C 17.4934 -14.8494
2 C8y C 16.6513 -13.7398
3 C8y C 16.9865 -12.3830
4 N1y N 18.2475 -11.8049
5 N2x N 18.8992 -14.8746
6 C5x C 19.5011 -12.4272
7 C1x C 19.7876 -13.7959
8 C8x C 15.9794 -11.4146
9 C8x C 14.6374 -11.8027
10 C8y C 14.3022 -13.1595
11 C8x C 15.3093 -14.1276
12 O5x O 20.5452 -11.4928
13 X Cl 12.9374 -13.5539
14 C8y C 16.8589 -16.0991
15 C8x C 15.4573 -16.0991
16 C1a C 18.2692 -10.4300
17 C8x C 14.7573 -17.3116
18 C8x C 15.4573 -18.5240
19 C8x C 16.8589 -18.5240
20 C8x C 17.5589 -17.3116
BOND 22
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 6 12 2
14 10 13 1
15 1 14 1
16 14 15 1
17 4 16 1
18 15 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 14 20 2
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