KEGG   DRUG: フルコナゾール
エントリ  
D00322                      Drug                                   

一般名   
フルコナゾール (JP17);
Fluconazole (JP17/USP/INN)
商品名   
  後発品
米国の商品 
  後発品
FLUCONAZOLE (A-S Medication Solutions), FLUCONAZOLE (A-S Medication Solutions), FLUCONAZOLE (A-S Medication Solutions), FLUCONAZOLE (A-S Medication Solutions), FLUCONAZOLE (A-S Medication Solutions), FLUCONAZOLE (A-S Medication Solutions), FLUCONAZOLE (A-S Medication Solutions), FLUCONAZOLE (A-S Medication Solutions), FLUCONAZOLE (ACETRIS HEALTH), FLUCONAZOLE (American Health Packaging), FLUCONAZOLE (Aurobindo Pharma Limited), FLUCONAZOLE (Aurobindo Pharma Limited), FLUCONAZOLE (AvPAK), FLUCONAZOLE (Baxter Healthcare Corporation), FLUCONAZOLE (BluePoint Laboratories), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Bryant Ranch Prepack), FLUCONAZOLE (Cadila Healthcare Limited), FLUCONAZOLE (Cardinal Health), FLUCONAZOLE (DIRECT RX), FLUCONAZOLE (Denton Pharma), FLUCONAZOLE (Denton Pharma), FLUCONAZOLE (Direct RX), FLUCONAZOLE (Direct Rx), FLUCONAZOLE (Dr. Reddy's Laboratories Limited), FLUCONAZOLE (Glenmark Pharmaceuticals), FLUCONAZOLE (Golden State Medical Supply), FLUCONAZOLE (Greenstone LLC), FLUCONAZOLE (Harris Pharmaceutical), FLUCONAZOLE (Hikma Pharmaceuticals USA), FLUCONAZOLE (Lake Erie Medical DBA Quality Care Products LLC), FLUCONAZOLE (Major Pharmaceuticals), FLUCONAZOLE (NorthStar Rx LLC), FLUCONAZOLE (NorthStar Rx LLC), FLUCONAZOLE (NuCare Pharmaceuticals), FLUCONAZOLE (NuCare Pharmaceuticals), FLUCONAZOLE (NuCare Pharmaceuticals), FLUCONAZOLE (NuCare Pharmaceuticals), FLUCONAZOLE (NuCare Pharmaceuticals), FLUCONAZOLE (NuCare Pharmaceuticals), FLUCONAZOLE (PD-Rx Pharmaceuticals), FLUCONAZOLE (PD-Rx Pharmaceuticals), FLUCONAZOLE (PD-Rx Pharmaceuticals), FLUCONAZOLE (PD-Rx Pharmaceuticals), FLUCONAZOLE (PD-Rx Pharmaceuticals), FLUCONAZOLE (Preferred Pharmaceutical), FLUCONAZOLE (Preferred Pharmaceuticals), FLUCONAZOLE (Preferred Pharmaceuticals), FLUCONAZOLE (Preferred Pharmaceuticals), FLUCONAZOLE (Preferred Pharmaceuticals), FLUCONAZOLE (Preferred Pharmaceuticals), FLUCONAZOLE (Preferred Pharmaceuticals), FLUCONAZOLE (Proficient Rx LP), FLUCONAZOLE (Proficient Rx LP), FLUCONAZOLE (Proficient Rx LP), FLUCONAZOLE (Proficient Rx LP), FLUCONAZOLE (Proficient Rx LP), FLUCONAZOLE (Proficient Rx LP), FLUCONAZOLE (Proficient Rx LP), FLUCONAZOLE (Proficient Rx LP), FLUCONAZOLE (REMEDYREPACK), FLUCONAZOLE (REMEDYREPACK), FLUCONAZOLE (REMEDYREPACK), FLUCONAZOLE (REMEDYREPACK), FLUCONAZOLE (RPK Pharmaceuticals), FLUCONAZOLE (RPK Pharmaceuticals), FLUCONAZOLE (Rising Health), FLUCONAZOLE (Rising Health), FLUCONAZOLE (Rising Pharmaceuticals), FLUCONAZOLE (Sagent Pharmaceuticals), FLUCONAZOLE (Sagent Pharmaceuticals), FLUCONAZOLE (Sagent Pharmaceuticals), FLUCONAZOLE (St Marys Medical Park Pharmacy), FLUCONAZOLE (St. Mary's Medical Park Pharmacy), FLUCONAZOLE (Taro Pharmaceuticals U.S.A.), FLUCONAZOLE (Teva Pharmaceuticals USA), FLUCONAZOLE (West-Ward Pharmaceuticals Corp), FLUCONAZOLE (Zydus Pharmaceuticals (USA)), FLUCONAZOLE (direct rx), FLUCONAZOLE IN SODIUM CHLORIDE (Hospira), FLUCONAZOLE IN SODIUM CHLORIDE (Woodward Pharma Services LLC), FLUCONAZOLE IN SODIUM CHLORIDE (Woodward Pharma Services LLC)
組成式   
C13H12F2N6O
質量    
306.1041
分子量   
306.2708
構造式   
Simcomp   
クラス   
抗真菌薬
 DG01523  トリアゾール系抗真菌薬
代謝酵素阻害薬
 DG01643  CYP2C9阻害薬
 DG01933  CYP2C19阻害薬
 DG01522  CYP3A4阻害薬
コード   
同一コード: C07002
薬効分類: 6290
ATCコード: D01AC15 J02AC01
化学構造グループ: DG00371
商品 (DG00371): D00322<JP/US> D01429<JP>
効能    
抗真菌薬, エルゴステロール合成阻害薬
  疾患
カンジダ症 [DS:H00363]
クリプトコッカス症 [DS:H00364]
コメント  
トリアゾール誘導体
ターゲット 
sterol 14alpha-demethylase [KO:K05917]
  パスウェイ
ko00100  ステロイドの生合成
相互作用  
CYP inhibition: CYP2C19 [HSA:1557], CYP2C9 [HSA:1559], CYP3A4 [HSA:1576]

構造マップ 
map07026  抗真菌薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 6  病原生物に対する医薬品
  62  化学療法剤
   629  その他の化学療法剤
    6290  その他の化学療法剤
     D00322  フルコナゾール (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 D 皮膚科用薬
  D01 皮膚科用抗真菌薬
   D01A 局所用抗真菌薬
    D01AC イミダゾールとトリアゾール誘導体
     D01AC15 フルコナゾール
      D00322  フルコナゾール (JP17) <JP/US>
 J 全身用抗感染薬
  J02 全身用抗真菌薬
   J02A 全身用抗真菌薬
    J02AC トリアゾール誘導体
     J02AC01 フルコナゾール
      D00322  フルコナゾール (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗真菌薬
  フルコナゾール
   D00322  フルコナゾール (JP17)
抗感染症薬 [BR:jp08307]
 抗真菌薬
  エルゴステロール合成阻害薬
   トリアゾール
    D00322  フルコナゾール (JP17) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00322  フルコナゾール
  D00322  フルコナゾールカプセル
  D00322  フルコナゾール注射液
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00322
リンク   
CAS: 86386-73-4
PubChem: 7847388
ChEBI: 46081
ChEMBL: CHEMBL106
DrugBank: DB00196
PDB-CCD: TPF[PDBj]
LigandBox: D00322
日化辞: J23.677B
LinkDB    

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