KEGG   DRUG: GabapentinHelp
Entry
D00332                      Drug                                   

Name
Gabapentin (JAN/USAN/INN);
Neurontin (TN);
Gralise (TN)
Product
  Generic
GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (A-S Medication Solutions), GABAPENTIN (ACETRIS HEALTH), GABAPENTIN (ACI Healthcare USA), GABAPENTIN (ACI Healthcare USA), GABAPENTIN (ATLANTIC BIOLOGICALS CORP.), GABAPENTIN (ATLANTIC BIOLOGICALS CORP.), GABAPENTIN (Acella Pharmaceuticals), GABAPENTIN (Actavis Pharma), GABAPENTIN (Actavis Pharma), GABAPENTIN (Aidarex Pharmaceuticals LLC), GABAPENTIN (Aidarex Pharmaceuticals LLC), GABAPENTIN (Aidarex Pharmaceuticals LLC), GABAPENTIN (Aidarex Pharmaceuticals LLC), GABAPENTIN (Aidarex Pharmaceuticals LLC), GABAPENTIN (Aidarex Pharmaceuticals LLC), GABAPENTIN (Aidarex Pharmaceuticals LLC), GABAPENTIN (Akron Pharma), GABAPENTIN (Akron Pharma), GABAPENTIN (Allied Pharma), GABAPENTIN (American Health Packaging), GABAPENTIN (American Health Packaging), GABAPENTIN (Amneal Pharmaceuticals LLC), GABAPENTIN (Amneal Pharmaceuticals LLC), GABAPENTIN (Amneal Pharmaceuticals of New York LLC), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Aphena Pharma Solutions - Tennessee), GABAPENTIN (Apotex Corp.), GABAPENTIN (Ascend Laboratories), GABAPENTIN (Ascend Laboratories), GABAPENTIN (Atlantic Biologicals Corps), GABAPENTIN (Atlantic Biologicals Corps), GABAPENTIN (Atlantic Biologicals Corps), GABAPENTIN (Aurobindo Pharma Limited), GABAPENTIN (Aurobindo Pharma Limited), GABAPENTIN (AvKARE), GABAPENTIN (AvPAK), GABAPENTIN (AvPAK), GABAPENTIN (Avera McKennan Hospital), GABAPENTIN (Avera McKennan Hospital), GABAPENTIN (Bi-Coastal Pharma International LLC), GABAPENTIN (Blenheim Pharmacal), GABAPENTIN (Blenheim Pharmacal), GABAPENTIN (Blenheim Pharmacal), GABAPENTIN (Blenheim Pharmacal), GABAPENTIN (Blenheim Pharmacal), GABAPENTIN (Blenheim Pharmacal), GABAPENTIN (BluePoint Laboratories), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Bryant Ranch Prepack), GABAPENTIN (Cadila Healthcare Limited), GABAPENTIN (Camber Pharmaceuticals), GABAPENTIN (Camber Pharmaceuticals), GABAPENTIN (Cardinal Health), GABAPENTIN (Cardinal Health), GABAPENTIN (Cardinal Health), GABAPENTIN (Cardinal Health), GABAPENTIN (Cardinal Health), GABAPENTIN (Cardinal Health), GABAPENTIN (Carilion Materials Management), GABAPENTIN (Carilion Materials Management), GABAPENTIN (Cipla USA), GABAPENTIN (Cipla USA), GABAPENTIN (Contract Pharmacy Services-PA), GABAPENTIN (Contract Pharmacy Services-PA), GABAPENTIN (Contract Pharmacy Services-PA), GABAPENTIN (Contract Pharmacy Services-PA), GABAPENTIN (Contract Pharmacy Services-PA), GABAPENTIN (Contract Pharmacy Services-PA), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECT RX), GABAPENTIN (DIRECTRX), GABAPENTIN (Department of State Health Services), GABAPENTIN (Department of State Health Services), GABAPENTIN (Direct Rx), GABAPENTIN (Direct Rx), GABAPENTIN (DirectRX), GABAPENTIN (DirectRX), GABAPENTIN (Dispensing Solutions), GABAPENTIN (Epic Pharma), GABAPENTIN (Exelan Pharmaceuticals), GABAPENTIN (Exelan Pharmaceuticals), GABAPENTIN (Glenmark Pharmaceuticals), GABAPENTIN (Golden State Medical Supply), GABAPENTIN (Greenstone LLC), GABAPENTIN (H.J. Harkins Company), GABAPENTIN (H.J. Harkins Company), GABAPENTIN (Hi-Tech Pharmacal), GABAPENTIN (Hikma Pharmaceutical), GABAPENTIN (Jiangsu Hengrui Medicine Co.), GABAPENTIN (Keltman Pharmaceuticals), GABAPENTIN (Kiel Laboratories), GABAPENTIN (Lake Erie Medica & Surgical Supply DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical & Surgical S6758upply DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Lake Erie Medical DBA Quality Care Products LLC), GABAPENTIN (Liberty Pharmaceuticals), GABAPENTIN (Liberty Pharmaceuticals), GABAPENTIN (MARKSANS PHARMA LIMITED), GABAPENTIN (MSM Repackaging), GABAPENTIN (Major Pharmaceuticals), GABAPENTIN (Major Pharmaceuticals), GABAPENTIN (Major Pharmaceuticals), GABAPENTIN (Marlex Pharmaceuticals), GABAPENTIN (Marlex Pharmaceuticals), GABAPENTIN (Mas Management Group), GABAPENTIN (McKesson Corporation), GABAPENTIN (McKesson Corporation), GABAPENTIN (McKesson Corporation), GABAPENTIN (MedVantx), GABAPENTIN (MedVantx), GABAPENTIN (MedVantx), GABAPENTIN (Medsource Pharmaceuticals), GABAPENTIN (Medsource Pharmaceuticals), GABAPENTIN (Medsource Pharmaceuticals), GABAPENTIN (Medsource Pharmaceuticals), GABAPENTIN (Megalith Pharmaceuticals), GABAPENTIN (Method Pharmaceuticals), GABAPENTIN (Method Pharmaceuticals), GABAPENTIN (Mylan Institutional), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (NCS HealthCare of KY), GABAPENTIN (New Horizon Rx Group), GABAPENTIN (NorthStar Rx LLC), GABAPENTIN (NorthStar Rx LLC), GABAPENTIN (NorthStar RxLLC), GABAPENTIN (Northwind Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (NuCare Pharmaceuticals), GABAPENTIN (Nucare Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN (PD-Rx Pharmaceuticals), GABAPENTIN KIT (Pharmaceutica North America), GABAPENTIN (Pharmaceutica North America), GABAPENTIN (Pharmaceutica North America), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Preferred Pharmaceuticals), GABAPENTIN (Proficient Rx), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABAPENTIN (Proficient Rx LP), GABA 300-EZS (PureTek Corporation), GABAPENTIN (QPharma), GABAPENTIN (QPharma), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (REMEDYREPACK), GABAPENTIN (RPK Pharmaceuticals), GABAPENTIN (RPK Pharmaceuticals), GABAPENTIN (Ranbaxy Pharmaceuticals), GABAPENTIN (ReadyMeds), GABAPENTIN (Rebel Distributors Corp), GABAPENTIN (Rebel Distributors Corp), GABAPENTIN (Rebel Distributors Corp), GABAPENTIN (Rebel Distributors Corp.), GABAPENTIN (Rebel Distributors Corp.), GABAPENTIN (RedPharm Drug), GABAPENTIN (RedPharm Drug), GABAPENTIN (RedPharm Drug), GABAPENTIN (RxChange), GABAPENTIN (RxChange), GABAPENTIN (Safecor Health), GABAPENTIN (ScieGen Pharmaceuticals), GABAPENTIN (ScieGen Pharmaceuticals), GABAPENTIN (Solco Healthcare U.S.), GABAPENTIN (Solco Healthcare U.S.), GABAPENTIN (Solco Healthcare U.S.), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St. Mary's Medical Park Pharmacy), GABAPENTIN (St.Mary's Medical Park Pharmacy), GABAPENTIN (Sterling Knight Pharmaceuticals), GABAPENTIN (Strides Pharma Science Limited), GABAPENTIN (Sun Pharmaceutical Industries), GABAPENTIN (Sun Pharmaceutical Industries), GABAPENTIN (TIME CAP LABORATORIES), GABAPENTIN (TMIG), GABAPENTIN (TYA Pharmaceuticals), GABAPENTIN (TYA Pharmaceuticals), GABAPENTIN (TYA Pharmaceuticals), GABAPENTIN (TYA Pharmaceuticals), GABAPENTIN (Taro Pharmaceuticals U.S.A.), GABAPENTIN (Teva Pharmaceuticals USA), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (Unit Dose Services), GABAPENTIN (West-ward Pharmaceutical Corp), GABAPENTIN (West-ward Pharmaceutical Corp), GABAPENTIN (Westminster Pharmaceuticals), GABAPENTIN (Westminster Pharmaceuticals), GABAPENTIN (Westwood Manufacturing), GABAPENTIN (Zydus Pharmaceuticals (USA))
Formula
C9H17NO2
Exact mass
171.1259
Mol weight
171.2368
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG02037  GABA mimetic antiepileptics
Other
 DG01575  Calcium channel blocker
  DG01574  Calcium channel alpha-2 delta blocker
Remark
Same as: C07018
Therapeutic category: 1139
ATC code: N03AX12
Chemical structure group: DG01245
Product (DG01245): D00332<JP/US> D09539<JP/US>
Efficacy
Anticonvulsant, Antiepileptic
  Disease
Postherpetic neuralgia [DS:H01624]
Comment
GABA [CPD:C00334] analog
Target
CACNA2D [HSA:781 9254 55799 93589] [KO:K04858 K04859 K04860 K04861]
SLC6A1 (GAT1) [HSA:6529] [KO:K05034]
  Pathway
hsa04010  MAPK signaling pathway
hsa04727  GABAergic synapse
Interaction
Drug interaction
Structure map
map07033  Anticonvulsants
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AX Other antiepileptics
     N03AX12 Gabapentin
      D00332  Gabapentin (JAN/USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Anticonvulsants
  Gamma-aminobutyric Acid (GABA) Augmenting Agents
   Gabapentin
    D00332  Gabapentin (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1139  Others
     D00332  Gabapentin (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA2D
     D00332  Gabapentin (JAN/USAN/INN) <JP/US>
 Transporters
  Solute carrier family
   SLC6
    SLC6A1 (GAT1)
     D00332  Gabapentin (JAN/USAN/INN) <JP/US>
Drug classes of therapeutic agents [br08360.html]
 Neurological agents
  D00332
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00332
Prodrugs [br08324.html]
 D00332
BRITE hierarchy
Other DBs
CAS: 60142-96-3
PubChem: 7847398
ChEBI: 42797
ChEMBL: CHEMBL940
DrugBank: DB00996
PDB-CCD: GBN[PDBj]
LigandBox: D00332
NIKKAJI: J39.388F
LinkDB All DBs
KCF data Show

ATOM        12
            1   C6a C    17.5000  -18.1300
            2   O6a O    18.6900  -18.8300
            3   C1b C    16.3100  -18.8300
            4   O6a O    17.5000  -16.7300
            5   C1z C    15.1200  -18.1300
            6   C1b C    13.9300  -18.8300
            7   N1a N    12.7400  -18.1300
            8   C1x C    13.9300  -16.0300
            9   C1x C    13.9300  -17.4300
            10  C1x C    16.3800  -17.4300
            11  C1x C    16.3800  -16.0300
            12  C1x C    15.1200  -15.3300
BOND        12
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     3   5 1
            5     5   6 1
            6     6   7 1
            7     8   9 1
            8     9   5 1
            9    10  11 1
            10   11  12 1
            11    8  12 1
            12    5  10 1

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