KEGG   DRUG: Sucralfate
Entry
D00446                      Drug                                   

Name
Sucralfate (USP/INN);
Sucralfate hydrate (JP17);
Carafate (TN)
Product
  Generic
SUCRALFATE (A-S Medication Solutions), SUCRALFATE (ATLANTIC BIOLOGICALS CORP.), SUCRALFATE (Aphena Pharma Solutions - Tennessee), SUCRALFATE (Aphena Pharma Solutions - Tennessee), SUCRALFATE (AvKARE), SUCRALFATE (Bryant Ranch Prepack), SUCRALFATE (Cardinal Health), SUCRALFATE (Cardinal Health), SUCRALFATE (Denton Pharma), SUCRALFATE (Greenstone LLC), SUCRALFATE (McKesson Corporation dba SKY Packaging), SUCRALFATE (Mylan Institutional), SUCRALFATE (NCS HealthCare of KY), SUCRALFATE (Nostrum Laboratories), SUCRALFATE (NuCare Pharmaceuticals), SUCRALFATE (NuCare Pharmaceuticals), SUCRALFATE (Par Pharmaceutical), SUCRALFATE (Precision Dose), SUCRALFATE (Preferred Pharmaceuticals), SUCRALFATE (REMEDYREPACK), SUCRALFATE (Teva Pharmaceuticals USA), SUCRALFATE (ATLANTIC BIOLOGICALS CORP.), SUCRALFATE (Amneal Pharmaceuticals LLC), SUCRALFATE (AvPAK)
Formula
C12H14O11R8. xAlH3O3. yH2O
Structure
Simcomp
Class
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
  DG02008  Gastric mucosal protectant
 DG02008  Gastric mucosal protectant
Remark
Therapeutic category: 2329
ATC code: A02BX02
Chemical structure group: DG00025
Product (DG00025): D00446<JP/US>
Efficacy
Anti-ulcerative, Antipepcin
  Disease
Duodenal ulcer [DS:H01634]
Comment
R: SO3Al(OH)2
Interaction
Structure map
map07038  Antiulcer drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A02 DRUGS FOR ACID RELATED DISORDERS
   A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
    A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
     A02BX02 Sucralfate
      D00446  Sucralfate (USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Protectants
   Sucralfate
    D00446  Sucralfate (USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   232  Peptic ulcer agents
    2329  Others
     D00446  Sucralfate (USP/INN); Sucralfate hydrate (JP17)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for digestive organs
  10 Antacids
   D00446  Sucralfate (USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Sucralfate
    D00446  Sucralfate (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00446  Sucralfate hydrate
Other DBs
PubChem: 7847512
DrugBank: DB00364
LinkDB
KCF data

ATOM        36
            1   C1z C    21.3189  -14.4796
            2   C1y C    21.7452  -15.7816
            3   O2a O    19.9999  -15.4079
            4   O2x O    22.4866  -13.6390
            5   C1b C    20.3381  -13.4814
            6   C1y C    23.1638  -15.7816
            7   O2a O    20.9221  -16.9200
            8   C1y C    18.7914  -16.1085
            9   C1y C    23.6133  -14.4563
            10  O2a O    23.9753  -16.9257
            11  R   R    21.4941  -18.1926
            12  C1y C    18.7914  -17.5096
            13  O2x O    17.5653  -15.4079
            14  C1b C    24.9503  -14.0361
            15  R   R    23.3915  -18.1985
            16  C1y C    17.5653  -18.2102
            17  O2a O    19.9940  -18.2102
            18  C1y C    16.3628  -16.1142
            19  C1y C    16.3628  -17.5096
            20  O2a O    17.5596  -19.6054
            21  R   R    19.9882  -19.6054
            22  C1b C    15.1484  -15.4079
            23  O2a O    15.1484  -18.2102
            24  R   R    16.3452  -20.3003
            25  O2a O    25.9815  -14.9828
            26  R   R    27.3074  -14.5660
            27  O2a O    19.0062  -13.8264
            28  R   R    18.0580  -12.8621
            29  O2a O    13.9161  -16.1145
            30  R   R    12.7100  -15.4133
            31  R   R    13.9105  -17.4949
            32  Z   Al   28.5340  -18.6793
            33  O1a O    28.5269  -17.2825
            34  O1a O    27.3279  -19.3838
            35  O1a O    29.9571  -19.3716
            36  O0  O    35.1075  -18.3830
BOND        35
            1     1   4 1
            2     1   5 1
            3     2   6 1
            4     2   7 1 #Down
            5     8   3 1 #Down
            6     4   9 1
            7     6  10 1 #Up
            8     7  11 1
            9     8  12 1
            10    8  13 1
            11    9  14 1 #Down
            12   10  15 1
            13   12  16 1
            14   12  17 1 #Down
            15   13  18 1
            16   16  19 1
            17   16  20 1 #Up
            18   17  21 1
            19   18  22 1 #Up
            20   19  23 1 #Down
            21   20  24 1
            22    6   9 1
            23   18  19 1
            24    1   2 1
            25    1   3 1 #Down
            26   14  25 1
            27   25  26 1
            28    5  27 1
            29   27  28 1
            30   22  29 1
            31   29  30 1
            32   23  31 1
            33   32  33 1
            34   32  34 1
            35   32  35 1
BRACKET     1    26.1800  -20.3700   26.1800  -16.4500
            1    31.0800  -16.4500   31.0800  -20.3700
            1  x
 ORIGINAL  1   32  33  34  35
 REPEAT    1
            2    33.4600  -19.3200   33.4600  -17.4300
            2    35.5600  -17.4300   35.5600  -19.3200
            2  y
 ORIGINAL  2   36
 REPEAT    2

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