KEGG   DRUG: Phenelzine sulfate
Entry
D00505                      Drug                                   

Name
Phenelzine sulfate (USP);
Nardil (TN)
Product
  Generic
Formula
C8H12N2. H2SO4
Exact mass
234.0674
Mol weight
234.2728
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01568  MAO inhibitor
  DG01519  Non-selective monoamine oxidase inhibitor
Remark
Same as: C07431
ATC code: N06AF03
Chemical structure group: DG00948
Product (DG00948): D00505<US>
Efficacy
Antidepressant, Monoamine oxidase (MAO) inhibitor
Target
MAO [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
Interaction
Structure map
map07027  Antidepressants
map07216  Catecholamine transferase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AF Monoamine oxidase inhibitors, non-selective
     N06AF03 Phenelzine
      D00505  Phenelzine sulfate (USP) <US>
USP drug classification [BR:br08302]
 Antidepressants
  Monoamine Oxidase Inhibitors
   Phenelzine
    D00505  Phenelzine sulfate (USP)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Amine oxidases
    MAO
     D00505  Phenelzine sulfate (USP) <US>
Other DBs
CAS: 156-51-4
PubChem: 7847571
ChEBI: 8061
ChEMBL: CHEMBL1200895
DrugBank: DB00780
LigandBox: D00505
NIKKAJI: J334.999C
LinkDB
KCF data

ATOM        15
            1   C8y C    20.2300  -17.5000
            2   C8x C    20.2300  -16.0300
            3   C8x C    19.0400  -18.2000
            4   C1b C    21.4200  -18.2000
            5   C8x C    19.0400  -15.3300
            6   C8x C    17.8500  -17.4300
            7   C1b C    22.6800  -17.5000
            8   C8x C    17.8500  -16.0300
            9   N1b N    23.8700  -18.2000
            10  N1a N    25.0600  -17.5000
            11  S4a S    29.6800  -16.8700
            12  O1d O    28.2800  -16.8700
            13  O1d O    31.0800  -16.8700
            14  O1d O    29.6800  -15.4700
            15  O1d O    29.6800  -18.2700
BOND        14
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     9  10 1
            10    6   8 2
            11   11  12 1
            12   11  13 1
            13   11  14 2
            14   11  15 2

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KEGG   DRUG: Phenelzine
Entry
D08349                      Drug                                   

Name
Phenelzine (BAN)
Formula
C8H12N2
Exact mass
136.1
Mol weight
136.1943
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01568  MAO inhibitor
  DG01519  Non-selective monoamine oxidase inhibitor
Remark
Same as: C07430
ATC code: N06AF03
Chemical structure group: DG00948
Product (DG00948): D00505<US>
Efficacy
Antidepressant, Monoamine oxidase (MAO) inhibitor
Target
MAO [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
Interaction
Structure map
map07027  Antidepressants
map07216  Catecholamine transferase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AF Monoamine oxidase inhibitors, non-selective
     N06AF03 Phenelzine
      D08349  Phenelzine (BAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Amine oxidases
    MAO
     D08349  Phenelzine (BAN)
Other DBs
CAS: 51-71-8
PubChem: 96025036
ChEBI: 8060
ChEMBL: CHEMBL1089
DrugBank: DB00780
LigandBox: D08349
NIKKAJI: J4.125D
LinkDB
KCF data

ATOM        10
            1   C8y C    23.7300  -17.5700
            2   C8x C    23.7300  -16.1700
            3   C8x C    22.4700  -18.2000
            4   C1b C    24.9200  -18.2000
            5   C8x C    22.5400  -15.4700
            6   C8x C    21.2800  -17.5700
            7   C1b C    26.1100  -17.5700
            8   C8x C    21.2800  -16.1700
            9   N1b N    27.3000  -18.2000
            10  N1a N    28.5600  -17.5700
BOND        10
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     9  10 1
            10    6   8 2

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