| Entry |
|
|---|
| Name |
Amobarbital (JP18/INN);
Isomytal (TN) |
|---|
| Formula |
C11H18N2O3
|
|---|
| Exact mass |
226.1317
|
|---|
| Mol weight |
226.2722
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG01567 GABA-A receptor agonist
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
|
|---|
| Remark |
| Therapeutic category: | 1125 |
|
|---|
| Efficacy |
Sedative-hypnotic |
|---|
| Comment |
Barbiturates
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CA Barbiturates, plain
N05CA02 Amobarbital
D00555 Amobarbital (JP18/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1125 Barbiturates and thiobarbiturates
D00555 Amobarbital (JP18/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00916 Amobarbital
D00555 Amobarbital
DG01567 GABA-A receptor agonist
DG00916 Amobarbital
D00555 Amobarbital
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
DG00916 Amobarbital
D00555 Amobarbital
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00555 Amobarbital (JP18/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00555 Amobarbital
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00555
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Cabinet order Article 3 (78 substances)
D00555
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00916 Amobarbital
DG01567 GABA-A receptor agonist
DG00916 Amobarbital
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
DG00916 Amobarbital
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 16
1 C1z C 20.9187 -17.4474
2 C5x C 20.9187 -18.8579
3 C5x C 19.7006 -16.7423
4 C1b C 22.4050 -17.4533
5 C1b C 20.9071 -16.0952
6 N1x N 19.7006 -19.5633
7 O5x O 22.1311 -19.5633
8 N2x N 18.4767 -17.4474
9 O5x O 19.7006 -15.3377
10 C1b C 23.1103 -16.4509
11 C1a C 22.1195 -15.3841
12 C2y C 18.4767 -18.8579
13 C1c C 24.5440 -16.4566
14 O1a O 17.2525 -19.5633
15 C1a C 25.2493 -17.6748
16 C1a C 25.2493 -15.2385
BOND 16
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 2
7 3 8 1
8 3 9 2
9 4 10 1
10 5 11 1
11 6 12 1
12 10 13 1
13 12 14 1
14 13 15 1
15 13 16 1
16 8 12 2
|
|---|
