| Entry |
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| Name |
Fosinopril sodium (USP);
Monopril (TN) |
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| Product |
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| Generic |
FOSINOPRIL SODIUM (A-S Medication Solutions), FOSINOPRIL SODIUM (A-S Medication Solutions), FOSINOPRIL SODIUM (Aurobindo Pharma Limited), FOSINOPRIL SODIUM (Bryant Ranch Prepack), FOSINOPRIL SODIUM (Bryant Ranch Prepack), FOSINOPRIL SODIUM (Bryant Ranch Prepack), FOSINOPRIL SODIUM (Bryant Ranch Prepack), FOSINOPRIL SODIUM (Chartwell RX), FOSINOPRIL SODIUM (Cipla USA), FOSINOPRIL SODIUM (Exelan Pharmaceuticals), FOSINOPRIL SODIUM (Preferred Pharmaceuticals), FOSINOPRIL SODIUM (Solco Healthcare LLC) |
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| Formula |
C30H45NO7P. Na
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| Exact mass |
585.2831
|
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| Mol weight |
585.6443
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
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| Remark |
| Product (DG00341): | D00622<US> |
| Product (mixture): | D10280<US> |
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| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
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| Disease |
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| Comment |
Active form of prodrug: Fosinoprilat [DR: D03772]
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
| map07217 | Renin-angiotensin system inhibitors |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA09 Fosinopril
D00622 Fosinopril sodium (USP) <US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Angiotensin-converting Enzyme (ACE) Inhibitors
Fosinopril
D00622 Fosinopril sodium (USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00341 Fosinopril
D00622 Fosinopril sodium
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00341 Fosinopril
D00622 Fosinopril sodium
Drug classes [BR:br08332]
Cardiovascular agent
DG01501 Angiotensin-converting enzyme inhibitor
D00622 Fosinopril sodium
DG03231 Antihypertensive
D00622 Fosinopril sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-dipeptidases
ACE (CD143)
D00622 Fosinopril sodium (USP) <US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00341 Fosinopril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00341 Fosinopril
Prodrugs [br08324.html]
DG00341
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 40
1 C8x C 10.2582 -15.1697
2 C8x C 10.2582 -16.5677
3 C8x C 11.4466 -17.2668
4 C8x C 12.7048 -16.5677
5 C8y C 12.7048 -15.1697
6 C8x C 11.4466 -14.4707
7 C1b C 13.8932 -14.4707
8 C1b C 15.1515 -15.1697
9 C1b C 16.3398 -14.4707
10 C1b C 17.5282 -15.1697
11 P1a P 18.7864 -14.4707
12 C1b C 19.9748 -15.1697
13 C5a C 21.1631 -14.4707
14 N1y N 22.4214 -15.1697
15 O3b O 18.7864 -13.0028
16 O5a O 21.1631 -13.0727
17 C1x C 22.8408 -16.4978
18 C1y C 24.2389 -16.4978
19 C1x C 24.6583 -15.1697
20 C1y C 23.5398 -14.3309
21 C1y C 24.9379 -17.7561
22 C1x C 24.2389 -18.9444
23 C1x C 24.9379 -20.1328
24 C1x C 26.3360 -20.1328
25 C1x C 27.0350 -18.9444
26 C1x C 26.3360 -17.7561
27 C6a C 23.5398 -12.9329
28 O6a O 24.7282 -12.2338 #-
29 O6a O 22.3515 -12.2338
30 O2b O 18.7864 -16.0085
31 C1c C 18.7864 -17.4066
32 O7a O 17.5981 -18.1056
33 C1c C 19.9748 -18.1056
34 C1a C 21.1631 -17.4066
35 C1a C 19.9748 -19.5037
36 C7a C 16.4097 -17.4066
37 C1b C 15.2214 -18.1056
38 O6a O 16.4097 -16.0085
39 C1a C 14.0330 -17.4066
40 Z Na 26.2661 -12.2338 #+
BOND 41
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 11 15 2
16 13 16 2
17 14 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 14 20 1
22 21 22 1
23 22 23 1
24 23 24 1
25 24 25 1
26 25 26 1
27 21 26 1
28 18 21 1 #Up
29 20 27 1 #Down
30 27 28 1
31 27 29 2
32 11 30 1
33 30 31 1
34 31 32 1 #Up
35 31 33 1
36 33 34 1
37 33 35 1
38 32 36 1
39 36 37 1
40 36 38 2
41 37 39 1
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