KEGG   DRUG: ノルトリプチリン塩酸塩
エントリ  
D00816                      Drug                                   

一般名   
ノルトリプチリン塩酸塩 (JP17);
Nortriptyline hydrochloride (JP17/USP/INN)
商品名   
米国の商品 
  後発品
NORTRIPTYLINE HCI (Direct_Rx), NORTRIPTYLINE HCI (Direct_Rx), NORTRIPTYLINE HCI (Direct_Rx), NORTRIPTYLINE HCL (Direct_Rx), NORTRIPTYLINE HYDROCHLORIDE (A-S Medication Solutions), NORTRIPTYLINE HYDROCHLORIDE (A-S Medication Solutions), NORTRIPTYLINE HYDROCHLORIDE (American Health Packaging), NORTRIPTYLINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), NORTRIPTYLINE HYDROCHLORIDE (AvPAK), NORTRIPTYLINE HYDROCHLORIDE (Bryant Ranch Prepack), NORTRIPTYLINE HYDROCHLORIDE (Clinical Solutions Wholesale), NORTRIPTYLINE HYDROCHLORIDE (DIRECT RX), NORTRIPTYLINE HYDROCHLORIDE (DIRECT RX), NORTRIPTYLINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), NORTRIPTYLINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), NORTRIPTYLINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), NORTRIPTYLINE HYDROCHLORIDE (Mayne Pharma), NORTRIPTYLINE HYDROCHLORIDE (Mayne Pharma), NORTRIPTYLINE HYDROCHLORIDE (NuCare Pharmaceuticals), NORTRIPTYLINE HYDROCHLORIDE (NuCare Pharmaceuticals), NORTRIPTYLINE HYDROCHLORIDE (NuCare Pharmaceuticals), NORTRIPTYLINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), NORTRIPTYLINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), NORTRIPTYLINE HYDROCHLORIDE (Pharmaceutical Associates), NORTRIPTYLINE HYDROCHLORIDE (Preferred Pharmaceuticals), NORTRIPTYLINE HYDROCHLORIDE (Preferred Pharmaceuticals), NORTRIPTYLINE HYDROCHLORIDE (Preferred Pharmaceuticals), NORTRIPTYLINE HYDROCHLORIDE (Proficient Rx LP), NORTRIPTYLINE HYDROCHLORIDE (Proficient Rx LP), NORTRIPTYLINE HYDROCHLORIDE (Proficient Rx LP), NORTRIPTYLINE HYDROCHLORIDE (Proficient Rx LP), NORTRIPTYLINE HYDROCHLORIDE (Proficient Rx LP), NORTRIPTYLINE HYDROCHLORIDE (Proficient Rx LP), NORTRIPTYLINE HYDROCHLORIDE (Proficient Rx LP), NORTRIPTYLINE HYDROCHLORIDE (Proficient Rx LP), NORTRIPTYLINE HYDROCHLORIDE (REMEDYREPACK), NORTRIPTYLINE HYDROCHLORIDE (REMEDYREPACK), NORTRIPTYLINE HYDROCHLORIDE (REMEDYREPACK), NORTRIPTYLINE HYDROCHLORIDE (REMEDYREPACK), NORTRIPTYLINE HYDROCHLORIDE (RedPharm Drug), NORTRIPTYLINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), NORTRIPTYLINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), NORTRIPTYLINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), NORTRIPTYLINE HYDROCHLORIDE (Taro Pharmaceuticals U.S.A.), NORTRIPTYLINE HYDROCHLORIDE (Teva Pharmaceuticals USA), NORTRIPTYLINE HYDROCHLORIDE (Unit Dose Services)
組成式   
C19H21N. HCl
質量    
299.1441
分子量   
299.8377
構造式   
Simcomp   
クラス   
精神神経系用薬
 DG01730  非選択的モノアミン再取り込み阻害薬
 DG01728  三環系抗うつ薬
代謝酵素基質薬
 DG01644  CYP2D6基質薬
コード   
薬効分類: 1179
ATCコード: N06AA10
化学構造グループ: DG00935
商品 (DG00935): D00816<JP/US>
効能    
抗うつ薬, セロトニン・ノルアドレナリン再取り込み阻害薬
ターゲット 
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
  パスウェイ
hsa04721  シナプス小胞サイクル
hsa04726  セロトニン作動性シナプス
代謝    
Enzyme: CYP2D6 [HSA:1565]
相互作用  

構造マップ 
map07027  抗うつ薬
map07048  抗片頭痛薬
map07234  神経伝達物質トランスポーター阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   117  精神神経用剤
    1179  その他の精神神経用剤
     D00816  ノルトリプチリン塩酸塩 (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N06 精神賦活薬
   N06A 抗うつ薬
    N06AA 非選択的モノアミン再取り込み阻害薬
     N06AA10 ノルトリプチリン
      D00816  ノルトリプチリン塩酸塩 (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗うつ薬
  三環系抗うつ薬
   ノルトリプチリン
    D00816  ノルトリプチリン塩酸塩 (JP17)
ターゲットに基づく医薬品分類 [BR:jp08310]
 トランスポーター
  SLC ファミリー
   SLC6
    SLC6A2 (NAT1)
     D00816  ノルトリプチリン塩酸塩 (JP17) <JP/US>
    SLC6A4 (HTT)
     D00816  ノルトリプチリン塩酸塩 (JP17) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00816  ノルトリプチリン塩酸塩
  D00816  ノルトリプチリン塩酸塩錠
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00816
ゲノムバイオマーカー [jp08341.html]
 医薬品応答に影響を与える多型と変異
  D00816
リンク   
CAS: 894-71-3
PubChem: 7847881
ChEBI: 7641
ChEMBL: CHEMBL1201156
DrugBank: DB00540
LigandBox: D00816
日化辞: J358.588C
LinkDB    

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