KEGG   DRUG: Morphine sulfate
Entry
D00842                      Drug                                   

Name
Morphine sulfate (USP);
Morphine sulfate hydrate (JP17);
Morphine sulfate pentahydrate;
Astramor PH (TN);
Avinza (TN);
Depodur (TN);
Kadian (TN);
MS contin (TN)
Product
MORPHINE SULFATE (ATLANTIC BIOLOGICALS CORP.), MORPHINE SULFATE (ATLANTIC BIOLOGICALS CORP.), KADIAN (Actavis Pharma), KADIAN (Allergan), MORPHINE SULFATE (Bryant Ranch Prepack), MORPHINE SULFATE (DIRECTRX), MORPHABOND (Daiichi Sankyo), MORPHINE SULFATE (Fresenius Kabi USA), MORPHINE SULFATE (Fresenius Kabi USA), MORPHINE SULFATE (Fresenius Kabi), MORPHINE SULFATE (Hikma Pharmaceuticals USA), DURAMORPH (Hikma Pharmaceuticals USA), MORPHINE SULFATE (Hospira), MORPHINE SULFATE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lohxa), MORPHINE SULFATE (Meridian Medical Technologies), MORPHINE SULFATE (Precision Dose), MORPHINE SULFATE (Precision Dose), MORPHINE SULFATE (RedPharm Drug), MS CONTIN (Rhodes Pharmaceuticals L.P.), MORPHINE SULFATE (West-Ward Pharmaceuticals Corp), MORPHINE SULFATE (West-Ward Pharmaceuticals Corp.), ARYMO (Zyla Life Sciences US)
  Generic
MORPHINE SULFATE (ANI Pharmaceuticals), MORPHINE SULFATE (ATLANTIC BIOLOGICALS CORP.), MORPHINE SULFATE (Actavis Pharma), MORPHINE SULFATE (Actavis Pharma), MORPHINE SULFATE (Actavis Pharma), MORPHINE SULFATE (American Health Packaging), MORPHINE SULFATE (Amneal Pharmaceuticals of New York LLC), MORPHINE SULFATE (Bryant Ranch Prepack), MORPHINE SULFATE (Bryant Ranch Prepack), MORPHINE SULFATE (Bryant Ranch Prepack), MORPHINE SULFATE (Civica), MORPHINE SULFATE (Direct_Rx), MORPHINE SULFATE (Hi-Tech Pharmacal), MORPHINE SULFATE (Hikma Pharmaceuticals USA), MORPHINE SULFATE (Hospira), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lupin Pharmaceuticals), MORPHINE SULFATE (Major Pharmaceuticals), MORPHINE SULFATE (Mayne Pharma), MORPHINE SULFATE ORAL SOLUTION CII (Nostrum Laboratories), MORPHINE SULFATE (Novel Laboratories), MORPHINE SULFATE (Pharmaceutical Associates), MITIGO (Piramal Critical Care), MORPHINE SULFATE (Quality Care Products), MORPHINE SULFATE (Quality Care Products), MORPHINE SULFATE (RedPharm Drug), MORPHINE SULFATE (RedPharm Drug), MORPHINE SULFATE (Rhodes Pharmaceuticals L. P.), MORPHINE SULFATE (Rhodes Pharmaceuticals L.P.), MORPHINE SULFATE (Safecor Health), MORPHINE SULFATE (SpecGx LLC), MORPHINE SULFATE (SpecGx LLC), MORPHINE SULFATE (Sun Pharmaceutical Industries), MORPHINE SULFATE (Tris Pharma), MORPHINE SULFATE (Upsher-Smith Laboratories), MORPHINE SULFATE (Upsher-Smith Laboratories), MORPHINE SULFATE (VistaPharm), MORPHINE SULFATE (Zydus Pharmaceuticals (USA)), MORPHINE SULFATE EXTENDED-RELEASE (Sun Pharmaceutical Industries), MORPHINE SULFATE ORAL SOLUTION (Nostrum Laboratories)
Formula
(C17H19NO3)2. H2SO4. 5H2O
Exact mass
758.2932
Mol weight
758.8302
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Metabolizing enzyme substrate
 DG02924  UGT substrate
Remark
Therapeutic category: 8114
ATC code: N02AA01
Chemical structure group: DG00810
Product (DG00810): D00842<JP/US> D02271<JP>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Opium alkaloid
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Metabolism
Enzyme: UGT [KO:K00699]
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Other map
map05032  Morphine addiction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AA Natural opium alkaloids
     N02AA01 Morphine
      D00842  Morphine sulfate (USP) <JP/US>
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Long-acting
   Morphine
    D00842  Morphine sulfate (USP)
  Opioid Analgesics, Short-acting
   Morphine
    D00842  Morphine sulfate (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 8  Narcotics
  81  Alkaloidal narcotics
   811  Opium alkaloids
    8114  Morphines
     D00842  Morphine sulfate (USP); Morphine sulfate hydrate (JP17)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D00842  Morphine sulfate (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00842  Morphine sulfate hydrate
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00842
Other DBs
CAS: 6211-15-0
PubChem: 7847907
ChEBI: 50731
ChEMBL: CHEMBL2103744
DrugBank: DB00295
LigandBox: D00842
NIKKAJI: J244.872F
LinkDB
KCF data

ATOM        52
            1   S4a S    29.2515  -20.6431
            2   O1d O    29.2457  -19.2411
            3   O1d O    29.2457  -22.0511
            4   O1d O    27.8437  -20.6374
            5   O1d O    30.6536  -20.6431
            6   O0  O    30.0311  -24.2752
            7   C1z C    18.8784  -23.6206
            8   C8y C    18.8784  -22.2988
            9   C1y C    20.0610  -24.3162
            10  C1y C    17.7653  -24.2467
            11  C1x C    20.0610  -22.9945
            12  C8y C    17.7653  -21.6727
            13  C8y C    20.0610  -21.6727
            14  C1y C    21.1741  -23.6206
            15  C2x C    20.0610  -25.5684
            16  O2x O    16.4436  -22.9248
            17  C1y C    17.7653  -25.5684
            18  C1x C    22.2871  -22.9945
            19  C8y C    17.7653  -20.3509
            20  C1x C    21.1741  -22.3683
            21  C8x C    20.0610  -20.3509
            22  N1y N    22.2871  -24.3162
            23  C2x C    18.8784  -26.2641
            24  O1a O    16.6523  -26.2641
            25  C8x C    18.9480  -19.7249
            26  O1a O    16.6523  -19.7249
            27  C1a C    23.6837  -24.3162
            28  O0  O    30.0311  -24.2752
            29  O0  O    30.0311  -24.2752
            30  O0  O    30.0311  -24.2752
            31  O0  O    30.0311  -24.2752
            32  C1z C    18.8784  -23.6206
            33  C8y C    18.8784  -22.2988
            34  C8y C    17.7653  -21.6727
            35  C8y C    17.7653  -20.3509
            36  C8x C    18.9480  -19.7249
            37  C8x C    20.0610  -20.3509
            38  C8y C    20.0610  -21.6727
            39  C1x C    21.1741  -22.3683
            40  C1y C    21.1741  -23.6206
            41  C1y C    20.0610  -24.3162
            42  C2x C    20.0610  -25.5684
            43  C2x C    18.8784  -26.2641
            44  C1y C    17.7653  -25.5684
            45  C1y C    17.7653  -24.2467
            46  O2x O    16.4436  -22.9248
            47  O1a O    16.6523  -26.2641
            48  N1y N    22.2871  -24.3162
            49  C1x C    22.2871  -22.9945
            50  C1x C    20.0610  -22.9945
            51  C1a C    23.6837  -24.3162
            52  O1a O    16.6523  -19.7249
BOND        54
            1     1   2 2
            2     1   3 2
            3     1   4 1
            4     1   5 1
            5     7   8 1
            6     7   9 1
            7     7  10 1
            8     7  11 1 #Up
            9     8  12 2
            10    8  13 1
            11    9  14 1
            12    9  15 1
            13   10  16 1 #Down
            14   10  17 1
            15   11  18 1
            16   12  19 1
            17   13  20 1
            18   13  21 2
            19   14  22 1 #Up
            20   15  23 2
            21   17  24 1 #Down
            22   19  25 2
            23   19  26 1
            24   12  16 1
            25   14  20 1
            26   17  23 1
            27   18  22 1
            28   21  25 1
            29   22  27 1
            30   32  33 1
            31   32  41 1
            32   32  45 1
            33   32  50 1 #Up
            34   33  34 2
            35   33  38 1
            36   41  40 1
            37   41  42 1
            38   45  46 1 #Down
            39   45  44 1
            40   50  49 1
            41   34  35 1
            42   38  39 1
            43   38  37 2
            44   40  48 1 #Up
            45   42  43 2
            46   44  47 1 #Down
            47   35  36 2
            48   35  52 1
            49   34  46 1
            50   40  39 1
            51   44  43 1
            52   49  48 1
            53   37  36 1
            54   48  51 1
BRACKET     1    28.0700  -25.2700   28.0700  -23.2400
            1    30.4500  -23.2400   30.4500  -25.2700
            1  5
 ORIGINAL  1    6
 REPEAT    1   29  30  31  32
            2    14.5600  -27.0200   14.5600  -18.6900
            2    25.4800  -18.6900   25.4800  -27.0200
            2  2
 ORIGINAL  2    7   8  12  19  25  21  13  20  14   9  15  23  17  10  16  24
            2   27  22  18  11  28  26
 REPEAT    2   33  34  35  36  37  38  39  40  41  42  43  44  45  46  47  48
            2   49  50  51  52  53  54

» Japanese version   » Back

KEGG   DRUG: Morphine hydrochloride hydrate
Entry
D02271                      Drug                                   

Name
Morphine hydrochloride hydrate (JP17);
Morphine hydrochloride trihydrate;
Anpec (TN)
Formula
C17H19NO3. 3H2O. HCl
Exact mass
375.1449
Mol weight
375.8444
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Metabolizing enzyme substrate
 DG02924  UGT substrate
Remark
Therapeutic category: 8114
ATC code: N02AA01
Chemical structure group: DG00810
Product (DG00810): D00842<JP/US> D02271<JP>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Opium alkaloid
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Metabolism
Enzyme: UGT [KO:K00699]
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Other map
map05032  Morphine addiction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AA Natural opium alkaloids
     N02AA01 Morphine
      D02271  Morphine hydrochloride hydrate (JP17) <JP>
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Long-acting
   Morphine
    D02271  Morphine hydrochloride hydrate (JP17)
Therapeutic category of drugs in Japan [BR:br08301]
 8  Narcotics
  81  Alkaloidal narcotics
   811  Opium alkaloids
    8114  Morphines
     D02271  Morphine hydrochloride hydrate (JP17)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D02271  Morphine hydrochloride hydrate (JP17) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02271  Morphine hydrochloride hydrate
  D02271  Morphine hydrochloride tablets
  D02271  Morphine hydrochloride injection
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D02271
Other DBs
CAS: 6055-06-7
PubChem: 7849330
ChEBI: 55348
DrugBank: DB00295
LigandBox: D02271
LinkDB
KCF data

ATOM        25
            1   X   Cl   27.0190  -23.0527
            2   O0  O    27.2299  -20.5437
            3   C1z C    19.1395  -23.6495
            4   C8y C    19.1395  -22.3255
            5   C1y C    20.3241  -24.3462
            6   C1y C    18.0246  -24.2766
            7   C1x C    20.3241  -23.0224
            8   C8y C    18.0246  -21.6984
            9   C8y C    20.3241  -21.6984
            10  C1y C    21.4390  -23.6495
            11  C2x C    20.3241  -25.6005
            12  O2x O    16.7007  -22.9526
            13  C1y C    18.0246  -25.6005
            14  C1x C    22.5538  -23.0224
            15  C8y C    18.0246  -20.3745
            16  C1x C    21.4390  -22.3952
            17  C8x C    20.3241  -20.3745
            18  N1y N    22.5538  -24.3462
            19  C2x C    19.1395  -26.2973
            20  O1a O    16.9098  -26.2973
            21  C8x C    19.2092  -19.7474
            22  O1a O    16.9098  -19.7474
            23  C1a C    23.9527  -24.3462
            24  O0  O    27.2299  -20.5437
            25  O0  O    27.2299  -20.5437
BOND        25
            1     3   4 1
            2     3   5 1
            3     3   6 1
            4     3   7 1 #Up
            5     4   8 2
            6     4   9 1
            7     5  10 1
            8     5  11 1
            9     6  12 1 #Down
            10    6  13 1
            11    7  14 1
            12    8  15 1
            13    9  16 1
            14    9  17 2
            15   10  18 1 #Up
            16   11  19 2
            17   13  20 1 #Down
            18   15  21 2
            19   15  22 1
            20    8  12 1
            21   10  16 1
            22   13  19 1
            23   14  18 1
            24   17  21 1
            25   18  23 1
BRACKET     1    25.0600  -21.4200   25.0600  -19.5300
            1    27.9300  -19.5300   27.9300  -21.4200
            1  3
 ORIGINAL  1    2
 REPEAT    1   25  26

» Japanese version   » Back

KEGG   DRUG: Morphine
Entry
D08233                      Drug                                   

Name
Morphine (BAN);
Morfina Dosa (TN);
Substitol (TN)
Formula
C17H19NO3
Exact mass
285.1365
Mol weight
285.3377
Structure
Simcomp
Source
Papaver somniferum [TAX:3469]
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Metabolizing enzyme substrate
 DG02924  UGT substrate
Remark
Same as: C01516
ATC code: N02AA01
Chemical structure group: DG00810
Product (DG00810): D00842<JP/US> D02271<JP>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Opium alkaloid
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Metabolism
Enzyme: UGT [KO:K00699]
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Other map
map00982  Drug metabolism - cytochrome P450
map05032  Morphine addiction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AA Natural opium alkaloids
     N02AA01 Morphine
      D08233  Morphine (BAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D08233  Morphine (BAN)
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D08233
Prodrugs [br08324.html]
 D08233
Other DBs
CAS: 57-27-2
PubChem: 96024921
ChEBI: 17303
ChEMBL: CHEMBL409938 CHEMBL70
DrugBank: DB00295
PDB-CCD: MOI[PDBj]
LigandBox: D08233
NIKKAJI: J2.323J
LinkDB
KCF data

ATOM        21
            1   C1z C    21.5533  -23.4873
            2   C8y C    21.5533  -22.2201
            3   C1y C    22.7502  -24.1914
            4   C1y C    20.4268  -24.1210
            5   C1x C    22.7502  -22.8537
            6   C8y C    20.4268  -21.5864
            7   C8y C    22.7502  -21.5864
            8   C1y C    23.8062  -23.4873
            9   C2x C    22.7502  -25.4587
            10  O2x O    19.0891  -22.7833
            11  C1y C    20.4268  -25.4587
            12  C1x C    24.9327  -22.8537
            13  C8y C    20.4268  -20.2487
            14  C1x C    23.8062  -22.2905
            15  C8x C    22.7502  -20.2487
            16  N1y N    24.9327  -24.1914
            17  C2x C    21.5533  -26.1627
            18  O1a O    19.3003  -26.1627
            19  C8x C    21.6237  -19.6151
            20  O1a O    19.3003  -19.6151
            21  C1a C    26.3408  -24.1914
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1 #Up
            5     2   6 2
            6     2   7 1
            7     3   8 1
            8     3   9 1
            9     4  10 1 #Down
            10    4  11 1
            11    5  12 1
            12    6  13 1
            13    7  14 1
            14    7  15 2
            15    8  16 1 #Up
            16    9  17 2
            17   11  18 1 #Down
            18   13  19 2
            19   13  20 1
            20    6  10 1
            21    8  14 1
            22   11  17 1
            23   12  16 1
            24   15  19 1
            25   16  21 1

» Japanese version   » Back

KEGG   DRUG: Morphine tartrate
Entry
D08234                      Drug                                   

Name
Morphine tartrate;
Morphine Tartrate (TN)
Formula
(C17H19NO3)2. C4H6O6
Exact mass
720.2894
Mol weight
720.7622
Structure
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Metabolizing enzyme substrate
 DG02924  UGT substrate
Remark
ATC code: N02AA01
Chemical structure group: DG00810
Product (DG00810): D00842<JP/US> D02271<JP>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Opium alkaloid
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Metabolism
Enzyme: UGT [KO:K00699]
Interaction
Structure map
map07224  Opioid receptor agonists/antagonists
Other map
map05032  Morphine addiction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AA Natural opium alkaloids
     N02AA01 Morphine
      D08234  Morphine tartrate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D08234  Morphine tartrate
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D08234
Other DBs
CAS: 302-31-8
PubChem: 96024922
LigandBox: D08234
LinkDB
KCF data

ATOM        52
            1   C1z C    17.5000  -23.2400
            2   C8y C    17.5000  -21.9100
            3   C1y C    18.6900  -23.9400
            4   C1y C    16.3800  -23.8700
            5   C1x C    18.6900  -22.5400
            6   C8y C    16.3800  -21.2800
            7   C8y C    18.6900  -21.2800
            8   C1y C    19.7400  -23.2400
            9   C2x C    18.6900  -25.2000
            10  O2x O    15.0500  -22.4700
            11  C1y C    16.3800  -25.2000
            12  C1x C    20.8600  -22.5400
            13  C8y C    16.3800  -19.9500
            14  C1x C    19.7400  -21.9800
            15  C8x C    18.6900  -19.9500
            16  N1y N    20.8600  -23.9400
            17  C2x C    17.5000  -25.9000
            18  O1a O    15.2600  -25.9000
            19  C8x C    17.5700  -19.3200
            20  O1a O    15.2600  -19.3200
            21  C1a C    22.2600  -23.9400
            22  O6a O    26.4600  -22.4700
            23  C6a C    27.6724  -21.7700
            24  C1c C    28.8849  -22.4700
            25  C1c C    30.0973  -21.7700
            26  C6a C    31.3097  -22.4700
            27  O6a O    32.5222  -21.7700
            28  O6a O    27.6724  -20.3702
            29  O6a O    31.3097  -23.8699
            30  O1a O    28.8849  -23.8698
            31  O1a O    30.0973  -20.3700
            32  C1z C    17.5000  -23.2400
            33  C8y C    17.5000  -21.9100
            34  C8y C    16.3800  -21.2800
            35  C8y C    16.3800  -19.9500
            36  C8x C    17.5700  -19.3200
            37  C8x C    18.6900  -19.9500
            38  C8y C    18.6900  -21.2800
            39  C1x C    19.7400  -21.9800
            40  C1y C    19.7400  -23.2400
            41  C1y C    18.6900  -23.9400
            42  C2x C    18.6900  -25.2000
            43  C2x C    17.5000  -25.9000
            44  C1y C    16.3800  -25.2000
            45  C1y C    16.3800  -23.8700
            46  O2x O    15.0500  -22.4700
            47  O1a O    15.2600  -25.9000
            48  N1y N    20.8600  -23.9400
            49  C1x C    20.8600  -22.5400
            50  C1x C    18.6900  -22.5400
            51  C1a C    22.2600  -23.9400
            52  O1a O    15.2600  -19.3200
BOND        59
            1    22  23 1
            2    23  24 1
            3    24  25 1
            4    25  26 1
            5    26  27 1
            6    23  28 2
            7    26  29 2
            8    24  30 1 #Up
            9    25  31 1 #Up
            10    1   2 1
            11    1   3 1
            12    1   4 1
            13    1   5 1 #Up
            14    2   6 2
            15    2   7 1
            16    3   8 1
            17    3   9 1
            18    4  10 1 #Down
            19    4  11 1
            20    5  12 1
            21    6  13 1
            22    7  14 1
            23    7  15 2
            24    8  16 1 #Up
            25    9  17 2
            26   11  18 1 #Down
            27   13  19 2
            28   13  20 1
            29    6  10 1
            30    8  14 1
            31   11  17 1
            32   12  16 1
            33   15  19 1
            34   16  21 1
            35   32  33 1
            36   32  41 1
            37   32  45 1
            38   32  50 1 #Up
            39   33  34 2
            40   33  38 1
            41   41  40 1
            42   41  42 1
            43   45  46 1 #Down
            44   45  44 1
            45   50  49 1
            46   34  35 1
            47   38  39 1
            48   38  37 2
            49   40  48 1 #Up
            50   42  43 2
            51   44  47 1 #Down
            52   35  36 2
            53   35  52 1
            54   34  46 1
            55   40  39 1
            56   44  43 1
            57   49  48 1
            58   37  36 1
            59   48  51 1
BRACKET     1    13.2300  -28.0000   13.2300  -17.7800
            1    24.2900  -17.7800   24.2900  -28.0000
            1  2
 ORIGINAL  1    1   2   6  13  19  15   7  14   8   3   9  17  11   4  10  18
            1   21  16  12   5  22  20
 REPEAT    1   33  34  35  36  37  38  39  40  41  42  43  44  45  46  47  48
            1   49  50  51  52  53  54

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