KEGG   DRUG: Ethambutol hydrochloride
Entry
D00878                      Drug                                   
Name
Ethambutol hydrochloride (JP18/USP);
Myambutol (TN)
Product
  Generic
Formula
C10H24N2O2. 2HCl
Exact mass
276.1371
Mol weight
277.2316
Structure
Simcomp
Class
Antibacterial
 DG01966  Antitubercular
Remark
Therapeutic category: 6225
ATC code: J04AK02
Chemical structure group: DG00643
Product (DG00643): D00878<JP/US>
Efficacy
Antibacterial (tuberculostatic), Arabinosyltransferase inhibitor
  Disease
Pulmonary tuberculosis [DS:H00342]
Target
arabinosyltransferase [KO:K11385 K11386 K11387]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AK Other drugs for treatment of tuberculosis
     J04AK02 Ethambutol
      D00878  Ethambutol hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Antimycobacterials
  Antituberculars
   Ethambutol
    D00878  Ethambutol hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   622  Tuberculosis preparations
    6225  Ethambutols
     D00878  Ethambutol hydrochloride (JP18/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01966  Antitubercular
   DG00643  Ethambutol
    D00878  Ethambutol hydrochloride
Antimicrobials [BR:br08307]
 Antibacterials
  Other antibacterials
   Arabinosyltransferase inhibitor
    D00878  Ethambutol hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00878  Ethambutol hydrochloride
Drug groups [BR:br08330]
 Antibacterial
  DG01966  Antitubercular
   DG00643  Ethambutol
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Other antibacterials
   Arabinosyltransferase inhibitor
    DG00643  Ethambutol
Other DBs
CAS: 1070-11-7
PubChem: 7847942
ChEBI: 4878
LigandBox: D00878
NIKKAJI: J349.674K
LinkDB
KCF data

ATOM        16
            1   C1c C    25.9405  -15.1673
            2   N1b N    27.1523  -15.8663
            3   C1b C    24.7230  -15.8663
            4   C1b C    25.9405  -13.7691
            5   C1b C    28.3698  -15.1673
            6   C1a C    23.5113  -15.1673
            7   O1a O    27.1523  -13.0643
            8   C1b C    29.5757  -15.8663
            9   N1b N    30.7875  -15.1673
            10  C1c C    32.0049  -15.8663
            11  C1b C    33.2167  -15.1673
            12  C1b C    32.0049  -17.2645
            13  C1a C    34.4283  -15.8663
            14  O1a O    33.2167  -17.9694
            15  X   Cl   38.8500  -16.0300
            16  X   Cl   38.8500  -16.0300
BOND        13
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     2   5 1
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   10  12 1 #Up
            12   11  13 1
            13   12  14 1
BRACKET     1    37.3100  -16.8000   37.3100  -15.1900
            1    39.7600  -15.1900   39.7600  -16.8000
            1  2
 ORIGINAL  1   15
 REPEAT    1   16

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