KEGG   DRUG: Liothyronine sodiumHelp
Entry
D01011                      Drug                                   

Name
Liothyronine sodium (JP17/USAN);
Cytomel (TN);
Triostat (TN)
Product
  Generic
LIOTHYRONINE SODIUM (A-S Medication Solutions), LIOTHYRONINE SODIUM (A-S Medication Solutions), LIOTHYRONINE SODIUM (Aidarex Pharmaceuticals LLC), LIOTHYRONINE SODIUM (Aidarex Pharmaceuticals LLC), LIOTHYRONINE SODIUM (AvKARE), LIOTHYRONINE SODIUM (Bryant Ranch Prepack), LIOTHYRONINE SODIUM (Bryant Ranch Prepack), LIOTHYRONINE SODIUM (Bryant Ranch Prepack), LIOTHYRONINE SODIUM (Carilion Materials Management), LIOTHYRONINE SODIUM (Carilion Materials Management), LIOTHYRONINE SODIUM (DIRECT RX), LIOTHYRONINE SODIUM (KAISER FOUNDATION HOSPITALS), LIOTHYRONINE SODIUM (KAISER FOUNDATION HOSPITALS), LIOTHYRONINE SODIUM (KAISER FOUNDATION HOSPITALS), LIOTHYRONINE SODIUM (Lake Erie Medical DBA Quality Care Products LLC), LIOTHYRONINE SODIUM (Mayne Pharma), LIOTHYRONINE SODIUM (Mylan Pharmaceuticals), LIOTHYRONINE SODIUM (Northwind Pharmaceuticals), LIOTHYRONINE SODIUM (Northwind Pharmaceuticals), LIOTHYRONINE SODIUM (NuCare Pharmaceuticals), LIOTHYRONINE SODIUM (PD-Rx Pharmaceuticals), LIOTHYRONINE SODIUM (PD-Rx Pharmaceuticals), LIOTHYRONINE SODIUM (PD-Rx Pharmaceuticals), LIOTHYRONINE SODIUM (Paddock Laboratories), LIOTHYRONINE SODIUM (Proficient Rx LP), LIOTHYRONINE SODIUM (SIGMAPHARM LABORATORIES), LIOTHYRONINE SODIUM (X-GEN Pharmaceuticals)
Formula
C15H11I3NO4. Na
Exact mass
672.772
Mol weight
672.9553
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01608  Thyroid hormone
 DG01953  Thyroid preparation
  DG01608  Thyroid hormone
Remark
Therapeutic category: 2431
ATC code: H03AA02
Chemical structure group: DG01372
Product (DG01372): D01011<JP/US>
Efficacy
Replenisher (thyroid hormone)
Target
NR1A (THR) [HSA:7067 7068] [KO:K05547 K08362]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04919  Thyroid hormone signaling pathway
Interaction
Drug interaction
Structure map
map07043  Antineoplastics - hormones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H03 THYROID THERAPY
   H03A THYROID PREPARATIONS
    H03AA Thyroid hormones
     H03AA02 Liothyronine sodium
      D01011  Liothyronine sodium (JP17/USAN) <JP/US>
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Thyroid)
  Liothyronine
   D01011  Liothyronine sodium (JP17/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   243  Thyroid and parathyroid hormone preparations
    2431  Thyroid hormones
     D01011  Liothyronine sodium (JP17/USAN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Thyroid hormone receptor (THR)
    NR1A (THR)
     D01011  Liothyronine sodium (JP17/USAN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01011  Liothyronine sodium
  D01011  Liothyronine sodium tablets
Drug classes of therapeutic agents [br08360.html]
 Endocrine and hormonal agents
  D01011
BRITE hierarchy
Other DBs
CAS: 55-06-1
PubChem: 7848074
ChEBI: 6484
ChEMBL: CHEMBL1201119
DrugBank: DB00279
LigandBox: D01011
NIKKAJI: J1.372B
LinkDB All DBs
KCF data Show

ATOM        24
            1   C8y C    22.6938  -17.3834
            2   O2a O    23.9120  -18.0919
            3   C8y C    21.4993  -18.0919
            4   C8y C    22.6938  -15.9897
            5   C8y C    25.1241  -18.7889
            6   C8x C    20.2754  -17.3834
            7   X   I    21.4993  -19.4857
            8   C8x C    21.4993  -15.2870
            9   X   I    23.9120  -15.2870
            10  C8x C    26.3421  -18.0919
            11  C8x C    25.1241  -20.1884
            12  C8y C    20.2754  -15.9897
            13  C8y C    27.5543  -18.7889
            14  C8x C    26.3421  -20.8911
            15  C1b C    19.0632  -15.2870
            16  C8y C    27.5543  -20.1884
            17  X   I    28.7605  -18.0919
            18  C1c C    17.8453  -15.9897
            19  O1a O    28.7605  -20.8911
            20  C6a C    16.6331  -15.2870
            21  N1a N    17.8453  -17.3834
            22  O6a O    16.6331  -13.8875
            23  O6a O    15.4149  -15.9897 #-
            24  Z   Na   13.6172  -13.9050 #+
BOND        24
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     4   8 2
            8     4   9 1
            9     5  10 1
            10    5  11 2
            11    6  12 2
            12   10  13 2
            13   11  14 1
            14   12  15 1
            15   13  16 1
            16   13  17 1
            17   15  18 1
            18   16  19 1
            19   18  20 1
            20   18  21 1 #Down
            21   20  22 2
            22   20  23 1
            23    8  12 1
            24   14  16 2

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