| Entry |
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| Name |
Gentamicin sulfate (JP18/USP);
Garamycin (TN);
Gentacin (TN) |
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| Product |
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| Generic |
GENTAK (Proficient Rx LP), GENTAMICIN (Eugia US LLC), GENTAMICIN (Eugia US LLC), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (HF Acquisition Co LLC), GENTAMICIN (Henry Schein), GENTAMICIN (Hikma Pharmaceuticals USA), GENTAMICIN (Medical Purchasing Solutions), GENTAMICIN (REMEDYREPACK), GENTAMICIN SULFATE (A-S Medication Solutions), GENTAMICIN SULFATE (A-S Medication Solutions), GENTAMICIN SULFATE (Asclemed USA), GENTAMICIN SULFATE (Asclemed USA), GENTAMICIN SULFATE (Bausch & Lomb Incorporated), GENTAMICIN SULFATE (Cardinal Health 107), GENTAMICIN SULFATE (Cosette Pharmaceuticals), GENTAMICIN SULFATE (Cosette Pharmaceuticals), GENTAMICIN SULFATE (DIRECT RX), GENTAMICIN SULFATE (HF Acquisition Co LLC), GENTAMICIN SULFATE (Henry Schein), GENTAMICIN SULFATE (Hospira), GENTAMICIN SULFATE (Medical Purchasing Solutions), GENTAMICIN SULFATE (Medsource Pharmaceuticals), GENTAMICIN SULFATE (NuCare Pharmaceuticals), GENTAMICIN SULFATE (NuCare Pharmaceuticals), GENTAMICIN SULFATE (Pacific Pharma), GENTAMICIN SULFATE (Padagis Israel Pharmaceuticals), GENTAMICIN SULFATE (Padagis Israel Pharmaceuticals), GENTAMICIN SULFATE (Preferred Pharmaceuticals), GENTAMICIN SULFATE (Preferred Pharmaceuticals), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (REMEDYREPACK), GENTAMICIN SULFATE (REMEDYREPACK), GENTAMICIN SULFATE (RPK Pharmaceuticals), GENTAMICIN SULFATE (RPK Pharmaceuticals), GENTAMICIN SULFATE (Sandoz), GENTAMICIN SULFATE IN SODIUM CHLORIDE (Baxter Healthcare Corporation), GENTAMICIN SULFATE OPTH SOLUTION (Direct_Rx) |
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| Formula |
C19H37N5O7(R1)(R2). H2SO4
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| Structure |
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| Simcomp |
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| Source |
Micromonospora purpurea [TAX: 1877]
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| Class |
Antibacterial
DG01447 Aminoglycoside antibiotic
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| Remark |
| Product (DG00401): | D01063<JP/US> |
| Product (mixture): | D04773<JP> |
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| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
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| Disease |
Bacterial endocarditis [DS: H00334] |
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| Comment |
R1,R2: See Gentamicin C [CPD: C01918]
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| Target |
30S ribosomal subunit |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX07 Gentamicin
D01063 Gentamicin sulfate (JP18/USP) <JP/US>
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01G AMINOGLYCOSIDE ANTIBACTERIALS
J01GB Other aminoglycosides
J01GB03 Gentamicin
D01063 Gentamicin sulfate (JP18/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA11 Gentamicin
D01063 Gentamicin sulfate (JP18/USP) <JP/US>
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA14 Gentamicin
D01063 Gentamicin sulfate (JP18/USP) <JP/US>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03A ANTIINFECTIVES
S03AA Antiinfectives
S03AA06 Gentamicin
D01063 Gentamicin sulfate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Aminoglycosides
Gentamicin
D01063 Gentamicin sulfate (JP18/USP)
Dermatological Agents
Topical Anti-infectives
Antibacterials, dermatological
Gentamicin
D01063 Gentamicin sulfate (JP18/USP)
Ophthalmic Agents
Ophthalmic Anti-Infectives
Antibacterials, Ophthalmic
Gentamicin
D01063 Gentamicin sulfate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1317 Ophthalmic antibiotics
D01063 Gentamicin sulfate (JP18/USP)
2 Agents affecting individual organs
26 Epidermides
263 Suppurative dermatosis agents
2634 Antibiotics for external use
D01063 Gentamicin sulfate (JP18/USP)
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6134 Amino sugars
D01063 Gentamicin sulfate (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00401 Gentamicin
D01063 Gentamicin sulfate
Drug classes [BR:br08332]
Antibacterial
DG01447 Aminoglycoside antibiotic
D01063 Gentamicin sulfate
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
D01063 Gentamicin sulfate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01063 Gentamicin sulfate
D01063 Gentamicin sulfate injection
D01063 Gentamicin sulfate ophthalmic solution
D01063 Gentamicin sulfate ointment
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00401 Gentamicin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
DG00401 Gentamicin
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 38
1 S4a S 53.5166 -22.8214
2 O1d O 53.5166 -21.4177
3 O1d O 53.5166 -24.1551
4 O1d O 54.9203 -22.8214
5 O1d O 52.1830 -22.8214
6 C1x C 38.9466 -19.9619
7 C1z C 38.9466 -21.3632
8 C1y C 40.1600 -22.0639
9 C1y C 41.3736 -21.3632
10 C1y C 41.3736 -19.9619
11 O2x O 40.1600 -19.2614
12 O2a O 42.6058 -19.2504
13 C1y C 43.8193 -18.5497
14 C1y C 45.0612 -19.2669
15 C1x C 46.2748 -18.5664
16 C1y C 46.2750 -17.1651
17 C1y C 45.0331 -16.4480
18 C1y C 43.8195 -17.1484
19 O1a O 42.6058 -22.0749
20 C1a C 38.5840 -22.7167
21 O1a O 37.5453 -21.3632
22 N1b N 40.1600 -23.4649
23 C1a C 38.9298 -24.1754
24 N1a N 45.0610 -20.6625
25 O1a O 42.6345 -16.4639
26 N1a N 47.5120 -16.4509
27 O2a O 45.0333 -15.0576
28 C1y C 46.2535 -14.3534
29 O2x O 47.4531 -15.0464
30 C1y C 48.6668 -14.3461
31 C1x C 48.6671 -12.9449
32 C1x C 47.4675 -12.2519
33 C1y C 46.2538 -12.9521
34 C1c C 49.8987 -15.0577
35 Z R# 51.0955 -14.3670
36 N1b N 49.8984 -16.4586
37 Z R# 51.0952 -17.1500
38 N1a N 45.0266 -12.2431
BOND 39
1 1 2 2
2 1 3 2
3 1 4 1
4 1 5 1
5 6 7 1
6 7 8 1
7 8 9 1
8 9 10 1
9 10 11 1
10 6 11 1
11 10 12 1 #Down
12 13 12 1 #Down
13 13 14 1
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 13 18 1
19 9 19 1 #Down
20 7 20 1 #Down
21 7 21 1 #Up
22 8 22 1 #Up
23 22 23 1
24 14 24 1 #Up
25 18 25 1 #Up
26 16 26 1 #Up
27 17 27 1 #Down
28 28 27 1 #Down
29 28 29 1
30 29 30 1
31 30 31 1
32 31 32 1
33 32 33 1
34 28 33 1
35 30 34 1
36 34 35 1 #Up
37 34 36 1
38 36 37 1
39 33 38 1 #Down
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