KEGG   DRUG: Piperidolate hydrochloride
Entry
D01165                      Drug                                   

Name
Piperidolate hydrochloride (JAN);
Dactil (TN)
Formula
C21H25NO2. HCl
Exact mass
359.1652
Mol weight
359.8896
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
Remark
Therapeutic category: 1249
ATC code: A03AA30
Chemical structure group: DG00034
Product (DG00034): D01165<JP>
Efficacy
Antispasmodic, Muscarinic acetylcholine receptor antagonist
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
Interaction
Structure map
map07038  Antiulcer drugs
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
    A03AA Synthetic anticholinergics, esters with tertiary amino group
     A03AA30 Piperidolate
      D01165  Piperidolate hydrochloride (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   124  Antispasmodics
    1249  Others
     D01165  Piperidolate hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D01165  Piperidolate hydrochloride (JAN) <JP>
Other DBs
CAS: 129-77-1
PubChem: 7848228
ChEBI: 32007
ChEMBL: CHEMBL1511957
LigandBox: D01165
NIKKAJI: J2.210.677E
LinkDB
KCF data

ATOM        25
            1   C8x C    28.0660  -21.8349
            2   C8x C    29.2704  -21.1216
            3   C8x C    29.2535  -19.7194
            4   C8x C    28.0357  -19.0366
            5   C8y C    26.8313  -19.7498
            6   C8x C    26.8446  -21.1459
            7   C1c C    25.6119  -19.0624
            8   C8y C    25.5975  -17.6628
            9   C7a C    24.4069  -19.7747
            10  O7a O    23.1874  -19.0874
            11  O6a O    24.4214  -21.1746
            12  C8x C    26.8035  -16.9561
            13  C8x C    26.7891  -15.5565
            14  C8x C    25.5697  -14.8693
            15  C8x C    24.3647  -15.5815
            16  C8x C    24.3793  -16.9812
            17  C1y C    21.9594  -19.8132
            18  C1x C    20.7542  -19.1336
            19  N1y N    19.5490  -19.8458
            20  C1x C    19.5631  -21.2458
            21  C1x C    20.7683  -21.9254
            22  C1x C    21.9736  -21.2132
            23  C1b C    18.3302  -19.1586
            24  C1a C    17.1230  -19.8720
            25  X   Cl   30.8735  -20.9800
BOND        26
            1     5   6 2
            2     6   1 1
            3     5   7 1
            4     8  12 2
            5    12  13 1
            6    13  14 2
            7    14  15 1
            8    15  16 2
            9    16   8 1
            10    7   8 1
            11    1   2 2
            12    7   9 1
            13    2   3 1
            14    9  10 1
            15    3   4 2
            16    9  11 2
            17    4   5 1
            18   10  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   17  22 1
            25   19  23 1
            26   23  24 1

» Japanese version   » Back

KEGG   DRUG: Piperidolate
Entry
D08382                      Drug                                   

Name
Piperidolate (INN)
Formula
C21H25NO2
Exact mass
323.1885
Mol weight
323.4287
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
Remark
ATC code: A03AA30
Chemical structure group: DG00034
Product (DG00034): D01165<JP>
Efficacy
Antispasmodic, Muscarinic acetylcholine receptor antagonist
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
Interaction
Structure map
map07038  Antiulcer drugs
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
    A03AA Synthetic anticholinergics, esters with tertiary amino group
     A03AA30 Piperidolate
      D08382  Piperidolate (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D08382  Piperidolate (INN)
Other DBs
CAS: 82-98-4
PubChem: 96025068
ChEMBL: CHEMBL1623992
LigandBox: D08382
NIKKAJI: J4.624H
LinkDB
KCF data

ATOM        24
            1   C8x C    23.5036  -19.6405
            2   C8x C    24.6958  -18.9392
            3   C8x C    24.6958  -17.5366
            4   C8x C    23.5036  -16.8352
            5   C8y C    22.2412  -17.5366
            6   C8x C    22.2413  -18.9392
            7   C1c C    21.0489  -16.8352
            8   C8y C    21.0489  -15.4326
            9   C7a C    19.8567  -17.6067
            10  O7a O    18.5943  -16.9054
            11  O6a O    19.8567  -19.0093
            12  C8x C    22.2412  -14.7312
            13  C8x C    22.2412  -13.3286
            14  C8x C    20.9788  -12.6974
            15  C8x C    19.7865  -13.3987
            16  C8x C    19.7865  -14.8014
            17  C1y C    17.4020  -17.6067
            18  C1x C    16.2097  -16.9054
            19  N1y N    15.0173  -17.6768
            20  C1x C    15.0175  -19.0795
            21  C1x C    16.2097  -19.7107
            22  C1x C    17.4020  -19.0093
            23  C1b C    13.7551  -16.9755
            24  C1a C    12.5628  -17.6768
BOND        26
            1     5   6 2
            2     6   1 1
            3     5   7 1
            4     8  12 2
            5    12  13 1
            6    13  14 2
            7    14  15 1
            8    15  16 2
            9    16   8 1
            10    7   8 1
            11    1   2 2
            12    7   9 1
            13    2   3 1
            14    9  10 1
            15    3   4 2
            16    9  11 2
            17    4   5 1
            18   10  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   17  22 1
            25   19  23 1
            26   23  24 1

» Japanese version   » Back

DBGET integrated database retrieval system