KEGG   DRUG: Perazine maleateHelp
Entry
D01412                      Drug                                   

Name
Perazine maleate (JAN)
Formula
C20H25N3S. (C4H4O4)2
Exact mass
571.1988
Mol weight
571.6419
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
Remark
ATC code: N05AB10
Chemical structure group: DG00881
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Structure map
map07029  Antipsychotics - phenothiazines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AB Phenothiazines with piperazine structure
     N05AB10 Perazine
      D01412  Perazine maleate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D01412  Perazine maleate (JAN)
BRITE hierarchy
Other DBs
CAS: 14516-56-4
PubChem: 7848475
ChEBI: 31979
LigandBox: D01412
NIKKAJI: J364.433B
LinkDB All DBs
KCF data Show

ATOM        40
            1   C8x C     8.9805  -16.6184
            2   C8x C     8.9805  -18.0205
            3   C8x C    10.1947  -18.7216
            4   C8y C    11.4090  -18.0205
            5   C8y C    11.4090  -16.6184
            6   C8x C    10.1947  -15.9174
            7   S2x S    12.6233  -18.7216
            8   C8y C    13.8375  -18.0205
            9   C8y C    13.8375  -16.6184
            10  N1y N    12.6233  -15.9174
            11  C8x C    15.0518  -18.7216
            12  C8x C    16.2660  -18.0205
            13  C8x C    16.2660  -16.6184
            14  C8x C    15.0518  -15.9174
            15  C1b C    12.6233  -14.5153
            16  C1b C    13.8396  -13.8130
            17  C1b C    15.0224  -14.4961
            18  N1y N    16.2141  -13.8080
            19  C1x C    17.4043  -14.4954
            20  C1x C    18.6176  -13.7951
            21  N1y N    18.6178  -12.3942
            22  C1x C    17.4275  -11.7067
            23  C1x C    16.2142  -12.4071
            24  C1a C    19.8444  -11.6859
            25  C6a C    24.0985  -17.2062
            26  C2b C    23.4234  -16.0415
            27  O6a O    23.4989  -18.4464
            28  O6a O    25.4491  -17.1999
            29  C2b C    21.8065  -16.0477
            30  C6a C    21.1375  -17.2185
            31  O6a O    19.7869  -17.2185
            32  O6a O    21.8190  -18.4525
            33  C6a C    24.0985  -17.2062
            34  C2b C    23.4234  -16.0415
            35  C2b C    21.8065  -16.0477
            36  C6a C    21.1375  -17.2185
            37  O6a O    19.7869  -17.2185
            38  O6a O    21.8190  -18.4525
            39  O6a O    23.4989  -18.4464
            40  O6a O    25.4491  -17.1999
BOND        41
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    9  14 1
            17   10  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   18  23 1
            27   21  24 1
            28   25  26 1
            29   25  27 1
            30   25  28 2
            31   26  29 2
            32   29  30 1
            33   30  31 1
            34   30  32 2
            35   33  34 1
            36   33  39 1
            37   33  40 2
            38   34  35 2
            39   35  36 1
            40   36  37 1
            41   36  38 2
BRACKET     1    18.6200  -18.9700   18.6200  -15.5400
            1    26.1100  -15.5400   26.1100  -18.9700
            1  2
 ORIGINAL  1   25  26  29  30  31  32  27  28
 REPEAT    1   33  34  35  36  37  38  39  40

» Japanese version   » Back

KEGG   DRUG: Perazine dimalonateHelp
Entry
D01860                      Drug                                   

Name
Perazine dimalonate (JAN)
Formula
C20H25N3S. (C3H4O4)2
Exact mass
547.1988
Mol weight
547.6205
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
Remark
ATC code: N05AB10
Chemical structure group: DG00881
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Structure map
map07029  Antipsychotics - phenothiazines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AB Phenothiazines with piperazine structure
     N05AB10 Perazine
      D01860  Perazine dimalonate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D01860  Perazine dimalonate (JAN)
BRITE hierarchy
Other DBs
CAS: 14777-25-4
PubChem: 7848922
ChEBI: 31978
LigandBox: D01860
NIKKAJI: J369.086E
LinkDB All DBs
KCF data Show

ATOM        38
            1   N1y N    25.4022  -18.9095
            2   C8y C    24.1939  -19.6274
            3   C8y C    26.6107  -19.6217
            4   C1b C    25.4314  -17.5084
            5   C8y C    24.1881  -21.0286
            6   C8x C    22.9797  -18.9211
            7   C8y C    26.6048  -21.0286
            8   C8x C    27.8192  -18.9211
            9   C1b C    26.5990  -16.8019
            10  S2x S    25.4022  -21.7174
            11  C8x C    22.9797  -21.7174
            12  C8x C    21.7654  -19.6217
            13  C8x C    27.8075  -21.7231
            14  C8x C    29.0333  -19.6332
            15  C8x C    21.7713  -21.0286
            16  C8x C    29.0275  -21.0343
            17  C1b C    27.8200  -17.4868
            18  N1y N    28.9957  -16.7884
            19  C1x C    30.2096  -17.4694
            20  C1x C    31.4133  -16.7544
            21  N1y N    31.3960  -15.3545
            22  C1x C    30.1820  -14.6735
            23  C1x C    28.9783  -15.3885
            24  C1a C    32.6356  -14.6184
            25  O6a O    35.4767  -20.0324
            26  C6a C    36.6893  -19.3303
            27  C1b C    37.9022  -20.0255
            28  C6a C    39.1151  -19.3233
            29  O6a O    40.3280  -20.0183
            30  O6a O    36.6863  -17.9260
            31  O6a O    39.1120  -17.9190
            32  O6a O    35.4767  -20.0324
            33  C6a C    36.6893  -19.3303
            34  C1b C    37.9022  -20.0255
            35  C6a C    39.1151  -19.3233
            36  O6a O    40.3280  -20.0183
            37  O6a O    39.1120  -17.9190
            38  O6a O    36.6863  -17.9260
BOND        39
            1     3   8 1
            2     4   9 1
            3     5  10 1
            4     5  11 1
            5     6  12 2
            6     7  13 1
            7     8  14 2
            8    11  15 2
            9    13  16 2
            10    7  10 1
            11   12  15 1
            12   14  16 1
            13    1   2 1
            14    1   3 1
            15    1   4 1
            16    2   5 2
            17    2   6 1
            18    3   7 2
            19    9  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   18  23 1
            27   21  24 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   28  29 1
            32   26  30 2
            33   28  31 2
            34   32  33 1
            35   33  34 1
            36   34  35 1
            37   35  36 1
            38   33  38 2
            39   35  37 2
BRACKET     1    34.0900  -20.7200   34.0900  -16.9400
            1    41.6500  -16.9400   41.6500  -20.7200
            1  2
 ORIGINAL  1   25  26  27  28  29  31  30
 REPEAT    1   32  33  34  35  36  37  38

» Japanese version   » Back

KEGG   DRUG: Perazine fendizoateHelp
Entry
D02608                      Drug                                   

Name
Perazine fendizoate (JAN)
Formula
(C20H14O4)2. C20H25N3S
Exact mass
975.3553
Mol weight
976.1431
Structure
Mol fileKCF fileDB search
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
Remark
ATC code: N05AB10
Chemical structure group: DG00881
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Structure map
map07029  Antipsychotics - phenothiazines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AB Phenothiazines with piperazine structure
     N05AB10 Perazine
      D02608  Perazine fendizoate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D02608  Perazine fendizoate (JAN)
BRITE hierarchy
Other DBs
PubChem: 17396778
LigandBox: D02608
LinkDB All DBs
KCF data Show

ATOM        72
            1   C8x C    19.2577  -19.4055
            2   C8x C    19.2577  -20.8067
            3   C8x C    20.4711  -21.5073
            4   C8y C    21.6846  -20.8067
            5   C8y C    21.6846  -19.4055
            6   C8x C    20.4711  -18.7050
            7   S2x S    22.8981  -21.5073
            8   C8y C    24.1115  -20.8067
            9   C8y C    24.1115  -19.4055
            10  N1y N    22.8981  -18.7050
            11  C8x C    25.3250  -21.5073
            12  C8x C    26.5384  -20.8067
            13  C8x C    26.5384  -19.4055
            14  C8x C    25.3250  -18.7050
            15  C1b C    22.8981  -17.3038
            16  C1b C    24.1136  -16.6020
            17  C1b C    25.2956  -17.2846
            18  N1y N    26.4865  -16.5970
            19  C1x C    27.6759  -17.2839
            20  C1x C    28.8884  -16.5841
            21  N1y N    28.8886  -15.1841
            22  C1x C    27.6991  -14.4971
            23  C1x C    26.4866  -15.1970
            24  C1a C    30.1144  -14.4763
            25  C8x C    32.4287  -19.3355
            26  C8x C    32.4287  -20.7367
            27  C8x C    33.6422  -21.4373
            28  C8x C    34.8557  -20.7367
            29  C8y C    34.8557  -19.3355
            30  C8y C    33.6422  -18.6350
            31  C6a C    33.6422  -17.2340
            32  O6a O    32.4119  -16.5235
            33  O6a O    34.8388  -16.5430
            34  C5a C    36.0878  -18.6239
            35  C8y C    37.2940  -19.3202
            36  O5a O    36.0875  -17.2339
            37  C8x C    37.2944  -20.7363
            38  C8x C    38.5081  -21.4366
            39  C8y C    39.7214  -20.7356
            40  C8y C    39.7209  -19.3194
            41  C8x C    38.5073  -18.6192
            42  C8y C    40.9227  -18.6252
            43  C8x C    42.1277  -19.3207
            44  C8x C    43.3411  -18.6200
            45  C8x C    43.3409  -17.2189
            46  C8x C    42.1358  -16.5233
            47  C8x C    40.9225  -17.2241
            48  O1a O    40.9306  -21.4333
            49  C8x C    32.4287  -19.3355
            50  C8x C    32.4287  -20.7367
            51  C8x C    33.6422  -21.4373
            52  C8x C    34.8557  -20.7367
            53  C8y C    34.8557  -19.3355
            54  C8y C    33.6422  -18.6350
            55  C6a C    33.6422  -17.2340
            56  O6a O    32.4119  -16.5235
            57  O6a O    34.8388  -16.5430
            58  C5a C    36.0878  -18.6239
            59  C8y C    37.2940  -19.3202
            60  C8x C    37.2944  -20.7363
            61  C8x C    38.5081  -21.4366
            62  C8y C    39.7214  -20.7356
            63  C8y C    39.7209  -19.3194
            64  C8x C    38.5073  -18.6192
            65  C8y C    40.9227  -18.6252
            66  C8x C    42.1277  -19.3207
            67  C8x C    43.3411  -18.6200
            68  C8x C    43.3409  -17.2189
            69  C8x C    42.1358  -16.5233
            70  C8x C    40.9225  -17.2241
            71  O1a O    40.9306  -21.4333
            72  O5a O    36.0875  -17.2339
BOND        79
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    9  14 1
            17   10  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   18  23 1
            27   21  24 1
            28   25  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 2
            32   29  30 1
            33   25  30 2
            34   30  31 1
            35   31  32 1
            36   31  33 2
            37   29  34 1
            38   34  35 1
            39   34  36 2
            40   35  37 2
            41   37  38 1
            42   38  39 2
            43   39  40 1
            44   40  41 2
            45   35  41 1
            46   40  42 1
            47   42  43 2
            48   43  44 1
            49   44  45 2
            50   45  46 1
            51   46  47 2
            52   42  47 1
            53   39  48 1
            54   49  50 1
            55   50  51 2
            56   51  52 1
            57   52  53 2
            58   53  54 1
            59   49  54 2
            60   54  55 1
            61   55  56 1
            62   55  57 2
            63   53  58 1
            64   58  59 1
            65   58  72 2
            66   59  60 2
            67   60  61 1
            68   61  62 2
            69   62  63 1
            70   63  64 2
            71   59  64 1
            72   63  65 1
            73   65  66 2
            74   66  67 1
            75   67  68 2
            76   68  69 1
            77   69  70 2
            78   65  70 1
            79   62  71 1
BRACKET     1    31.2200  -21.9800   31.2200  -15.6100
            1    43.7500  -15.6100   43.7500  -21.9800
            1  2
 ORIGINAL  1   25  26  27  28  29  30  31  32  33  34  35  37  38  39  40  41
            1   42  43  44  45  46  47  48  36
 REPEAT    1   49  50  51  52  53  54  55  56  57  58  59  60  61  62  63  64
            1   65  66  67  68  69  70  71  72

» Japanese version   » Back

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