KEGG   DRUG: MeticraneHelp
Entry
D01605                      Drug                                   

Name
Meticrane (JP17/INN);
Arresten (TN)
Formula
C10H13NO4S2
Exact mass
275.0286
Mol weight
275.3445
Structure
Mol fileKCF fileDB search
Class
Cardiovascular agent
 DG01690  Sulfonamide diuretic
 DG02992  Thiazide related diuretic
Remark
Therapeutic category: 2149
ATC code: C03BA09
Efficacy
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor
Comment
Sulfonamide derivative
Target
SLC12A3 (TSC) [HSA:6559] [KO:K14426]
Interaction
Drug interaction
Structure map
map07017  Sulfonamide derivatives - diuretics
map07233  Ion transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
    C03BA Sulfonamides, plain
     C03BA09 Meticrane
      D01605  Meticrane (JP17/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D01605  Meticrane (JP17/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3 (TSC)
     D01605  Meticrane (JP17/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01605  Meticrane
BRITE hierarchy
Other DBs
CAS: 1084-65-7
PubChem: 7848668
ChEBI: 31839
ChEMBL: CHEMBL1318341
LigandBox: D01605
NIKKAJI: J7.246J
LinkDB All DBs
KCF data Show

ATOM        17
            1   C1x C    11.4100  -18.1300
            2   C1x C    11.4100  -19.5300
            3   C1x C    12.6224  -20.2300
            4   C8y C    13.8349  -19.5300
            5   C8y C    13.8349  -18.1300
            6   S2x S    12.6224  -17.4300
            7   C8x C    15.0473  -20.2300
            8   C8y C    16.2597  -19.5300
            9   C8y C    16.2597  -18.1300
            10  C8x C    15.0473  -17.4300
            11  O3c O    13.6124  -16.4401
            12  O3c O    11.6325  -16.4401
            13  S4a S    17.4573  -17.4385
            14  N1a N    18.6697  -16.7385
            15  O3c O    16.7471  -16.2079
            16  O3c O    18.1465  -18.6327
            17  C1a C    17.4573  -20.2215
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 2
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 2
            12    6  11 2
            13    6  12 2
            14    9  13 1
            15   13  14 1
            16   13  15 2
            17   13  16 2
            18    8  17 1

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