KEGG   DRUG: Tiquizium bromide
Entry
D01875                      Drug                                   

Name
Tiquizium bromide (JAN/INN);
Thiaton (TN)
Formula
C19H24NS2. Br
Exact mass
409.0534
Mol weight
410.4346
Structure
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
Remark
Therapeutic category: 1231
Product: D01875<JP>
Efficacy
Antispasmodic, Muscarinic acetylcholine receptor antagonist
Target
CHRM3 [HSA:1131] [KO:K04131]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04971  Gastric acid secretion
Interaction
Structure map
map07038  Antiulcer drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   123  Autonomic nervous system agents
    1231  Quaternary ammoniums
     D01875  Tiquizium bromide (JAN/INN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for digestive organs
  15 Stomach pain and cramp relievers
   D01875  Tiquizium bromide (JAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Tiquizium
    D01875  Tiquizium bromide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM3
     D01875  Tiquizium bromide (JAN/INN) <JP>
Rx-to-OTC switch list in Japan [br08314.html]
 D01875
Other DBs
CAS: 71731-58-3
PubChem: 7848937
ChEBI: 32232
ChEMBL: CHEMBL2360047
LigandBox: D01875
NIKKAJI: J349.600G
LinkDB
KCF data

ATOM        23
            1   C1x C    20.5800  -23.9400
            2   C1x C    21.7700  -23.3100
            3   C2y C    21.7700  -21.9100
            4   C1x C    20.5800  -21.2100
            5   C2c C    23.0300  -21.2800
            6   C8y C    24.1500  -21.9800
            7   C8y C    23.0300  -19.8800
            8   C8x C    21.9423  -19.0650
            9   C8x C    22.4162  -17.7532
            10  C8x C    23.7480  -17.7375
            11  S2x S    24.1833  -19.0864
            12  C8x C    24.6400  -23.2400
            13  C8x C    26.0400  -23.1700
            14  C8x C    26.3900  -21.8400
            15  S2x S    25.2700  -21.0700
            16  C1y C    19.3900  -23.2400
            17  N2y N    19.3900  -21.9100 #+
            18  C1x C    18.2000  -21.2100
            19  C1x C    17.0100  -21.8400
            20  C1x C    17.0100  -23.2400
            21  C1x C    18.2000  -23.9400
            22  C1a C    19.3900  -19.8800
            23  X   Br   18.1300  -18.9700 #-
BOND        25
            1     8   9 1
            2     9  10 2
            3    10  11 1
            4    11   7 1
            5    16   1 1
            6     1   2 1
            7     6  12 2
            8    12  13 1
            9    13  14 2
            10   14  15 1
            11   15   6 1
            12    2   3 1
            13    3   5 2
            14    3   4 1
            15    5   6 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   21  16 1
            22    4  17 1
            23    5   7 1
            24   17  22 1 #Up
            25    7   8 2

» Japanese version   » Back

DBGET integrated database retrieval system