| Entry |
|
|---|
| Name |
Naltrexone hydrochloride (USP);
ReVia (TN) |
|---|
| Product |
|
|---|
| Generic |
NALTREXONE HYDROCHLORIDE (A-S Medication Solutions), NALTREXONE HYDROCHLORIDE (A-S Medication Solutions), NALTREXONE HYDROCHLORIDE (Accord Healthcare), NALTREXONE HYDROCHLORIDE (American Health Packaging), NALTREXONE HYDROCHLORIDE (AvKARE), NALTREXONE HYDROCHLORIDE (Bryant Ranch Prepack), NALTREXONE HYDROCHLORIDE (Bryant Ranch Prepack), NALTREXONE HYDROCHLORIDE (Bryant Ranch Prepack), NALTREXONE HYDROCHLORIDE (Bryant Ranch Prepack), NALTREXONE HYDROCHLORIDE (Bryant Ranch Prepack), NALTREXONE HYDROCHLORIDE (Bryant Ranch Prepack), NALTREXONE HYDROCHLORIDE (Bryant Ranch Prepack), NALTREXONE HYDROCHLORIDE (Chartwell RX), NALTREXONE HYDROCHLORIDE (Heritage Pharmaceuticals Inc d/b/a Avet Pharmaceuticals), NALTREXONE HYDROCHLORIDE (Major Pharmaceuticals), NALTREXONE HYDROCHLORIDE (NuCare Pharmceuticals), NALTREXONE HYDROCHLORIDE (Precision Dose), NALTREXONE HYDROCHLORIDE (Precision Dose), NALTREXONE HYDROCHLORIDE (REMEDYREPACK), NALTREXONE HYDROCHLORIDE (SpecGx LLC), NALTREXONE HYDROCHLORIDE (Sun Pharmaceutical Industries), NALTREXONE HYDROCHLORIDE (TAGI Pharma) |
|---|
| Formula |
C20H23NO4. HCl
|
|---|
| Exact mass |
377.1394
|
|---|
| Mol weight |
377.8619
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Analgesic
DG01586 Opioid receptor antagonist
|
|---|
| Remark |
| Product (DG00997): | D05113<US> D02095<US> |
| Product (mixture): | D10751<US> |
|
|---|
| Efficacy |
Antialcohol dependence, Narcotic antagonist, Opioid receptor antagonist |
|---|
| Disease |
Alcohol dependence [DS: H01611] |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07B DRUGS USED IN ADDICTIVE DISORDERS
N07BB Drugs used in alcohol dependence
N07BB04 Naltrexone
D02095 Naltrexone hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Anti-Addiction/Substance Abuse Treatment Agents
Alcohol Deterrents/Anti-craving
Naltrexone
D02095 Naltrexone hydrochloride (USP)
Opioid Dependence
Naltrexone
D02095 Naltrexone hydrochloride (USP)
Drug groups [BR:br08330]
Analgesic
DG01586 Opioid receptor antagonist
DG00997 Naltrexone
D02095 Naltrexone hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D02095 Naltrexone hydrochloride (USP) <US>
OPRK1
D02095 Naltrexone hydrochloride (USP) <US>
OPRD1
D02095 Naltrexone hydrochloride (USP) <US>
Drug groups [BR:br08330]
Analgesic
DG01586 Opioid receptor antagonist
DG00997 Naltrexone
|
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| Other DBs |
|
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| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 X Cl 37.1700 -16.1000
2 C1z C 29.4000 -17.5000
3 C8y C 29.4000 -16.1700
4 C1z C 30.5900 -18.2000
5 C1y C 28.2800 -18.1300
6 C1x C 30.5900 -16.8700
7 C8y C 28.2800 -15.5400
8 C8y C 30.5900 -15.5400
9 C1y C 31.7100 -17.5000
10 C1x C 30.5900 -19.4600
11 O2x O 27.0200 -16.8000
12 C5x C 28.2800 -19.4600
13 C1x C 32.8300 -16.8700
14 C8y C 28.2800 -14.2100
15 C1x C 31.7100 -16.2400
16 C8x C 30.5900 -14.2100
17 N1y N 32.8300 -18.2000
18 C1x C 29.4000 -20.1600
19 C8x C 29.4700 -13.5800
20 O1a O 27.2300 -13.5800
21 O1a O 31.8500 -19.1100
22 C1b C 34.2300 -18.2000
23 C1y C 34.9300 -19.3900
24 C1x C 34.9300 -20.7900
25 C1x C 36.1200 -20.0900
26 O5x O 27.0900 -20.1600
BOND 30
1 2 3 1
2 2 4 1
3 2 5 1
4 2 6 1 #Up
5 3 7 2
6 3 8 1
7 4 9 1
8 4 10 1
9 5 11 1 #Down
10 5 12 1
11 6 13 1
12 7 14 1
13 8 15 1
14 8 16 2
15 9 17 1 #Up
16 10 18 1
17 14 19 2
18 14 20 1
19 7 11 1
20 9 15 1
21 12 18 1
22 13 17 1
23 16 19 1
24 4 21 1 #Up
25 17 22 1
26 22 23 1
27 23 24 1
28 23 25 1
29 24 25 1
30 12 26 2
|
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