KEGG   DRUG: Biperiden hydrochlorideHelp
Entry
D02246                      Drug                                   

Name
Biperiden hydrochloride (JP17/USP);
Tasmolin (TN)
Formula
C21H29NO. HCl
Exact mass
347.2016
Mol weight
347.922
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
 DG01745  Anticholinergic antiparkinson agent
 DG01967  Antiparkinson agent
  DG01745  Anticholinergic antiparkinson agent
Remark
Therapeutic category: 1162
ATC code: N04AA02
Chemical structure group: DG00852
Product (DG00852): D02246<JP> D02247<JP>
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
  Disease
Parkinsonism [DS:H01600]
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Drug interaction
Structure map
map07057  Antiparkinsonian agents
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA02 Biperiden
      D02246  Biperiden hydrochloride (JP17/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1162  Biperidens
     D02246  Biperiden hydrochloride (JP17/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D02246  Biperiden hydrochloride (JP17/USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02246  Biperiden hydrochloride
BRITE hierarchy
Other DBs
CAS: 1235-82-1
PubChem: 7849305
ChEMBL: CHEMBL1201035
DrugBank: DB00810
LigandBox: D02246
NIKKAJI: J349.697J
LinkDB All DBs
KCF data Show

ATOM        24
            1   X   Cl   28.7000  -22.4700
            2   C1y C    21.8400  -20.9300
            3   C1d C    21.8400  -22.3300
            4   C1y C    23.1000  -20.2300
            5   C1x C    20.6500  -20.2300
            6   C8y C    23.1000  -23.0300
            7   C1b C    20.6500  -23.0300
            8   C1x C    22.1200  -19.2500
            9   C2x C    23.1000  -18.8300
            10  C1y C    20.6500  -18.8300
            11  C8x C    23.1000  -24.4300
            12  C8x C    24.2900  -22.3300
            13  C1b C    19.4600  -22.3300
            14  C2x C    21.9100  -18.1300
            15  C8x C    24.2200  -25.1300
            16  C8x C    25.4800  -23.1000
            17  N1y N    18.2000  -23.0300
            18  C8x C    25.4800  -24.4300
            19  C1x C    18.2000  -24.4300
            20  C1x C    17.0100  -22.3300
            21  C1x C    17.0100  -25.0600
            22  C1x C    15.8200  -23.0300
            23  C1x C    15.8200  -24.3600
            24  O1a O    23.0524  -21.6300
BOND        26
            1     2   3 1
            2     2   4 1
            3     2   5 1
            4     3   6 1
            5     3   7 1
            6     4   8 1
            7     4   9 1
            8     5  10 1
            9     6  11 1
            10    6  12 2
            11    7  13 1
            12    9  14 2
            13   11  15 2
            14   12  16 1
            15   13  17 1
            16   15  18 1
            17   17  19 1
            18   17  20 1
            19   19  21 1
            20   20  22 1
            21   21  23 1
            22    8  10 1
            23   10  14 1
            24   16  18 2
            25   22  23 1
            26    3  24 1

» Japanese version   » Back

KEGG   DRUG: Biperiden lactateHelp
Entry
D02247                      Drug                                   

Name
Biperiden lactate (JAN/USP);
Tasmolin (TN)
Formula
C21H29NO. C3H6O3
Exact mass
401.2566
Mol weight
401.539
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
 DG01745  Anticholinergic antiparkinson agent
 DG01967  Antiparkinson agent
  DG01745  Anticholinergic antiparkinson agent
Remark
Therapeutic category: 1162
ATC code: N04AA02
Chemical structure group: DG00852
Product (DG00852): D02246<JP> D02247<JP>
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
  Disease
Parkinsonism [DS:H01600]
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Drug interaction
Structure map
map07057  Antiparkinsonian agents
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA02 Biperiden
      D02247  Biperiden lactate (JAN/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1162  Biperidens
     D02247  Biperiden lactate (JAN/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D02247  Biperiden lactate (JAN/USP) <JP>
BRITE hierarchy
Other DBs
CAS: 7085-45-2
PubChem: 7849306
ChEMBL: CHEMBL1201067
DrugBank: DB00810
LigandBox: D02247
NIKKAJI: J231.542D
LinkDB All DBs
KCF data Show

ATOM        29
            1   O1a O    26.1800  -22.4700
            2   C1c C    27.4400  -23.1700
            3   C6a C    28.6300  -22.4700
            4   O6a O    29.8200  -23.1700
            5   C1a C    27.4400  -24.5700
            6   O6a O    28.6300  -21.0700
            7   C1y C    20.7900  -20.9300
            8   C1d C    20.7900  -22.3300
            9   C1y C    22.0500  -20.2300
            10  C1x C    19.6000  -20.2300
            11  C8y C    22.0500  -23.0300
            12  C1b C    19.6000  -23.0300
            13  C1x C    21.0700  -19.2500
            14  C2x C    22.0500  -18.8300
            15  C1y C    19.6700  -18.8300
            16  C8x C    22.0500  -24.4300
            17  C8x C    23.2400  -22.3300
            18  C1b C    18.4100  -22.3300
            19  C2x C    20.8600  -18.1300
            20  C8x C    23.1700  -25.1300
            21  C8x C    24.4300  -23.0300
            22  N1y N    17.1500  -23.0300
            23  C8x C    24.4300  -24.4300
            24  C1x C    17.1500  -24.3600
            25  C1x C    15.9600  -22.3300
            26  C1x C    15.9600  -25.0600
            27  C1x C    14.7700  -23.0300
            28  C1x C    14.7700  -24.3600
            29  O1a O    22.0024  -21.6300
BOND        31
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     2   5 1
            5     3   6 2
            6     7   8 1
            7     7   9 1
            8     7  10 1
            9     8  11 1
            10    8  12 1
            11    9  13 1
            12    9  14 1
            13   10  15 1
            14   11  16 1
            15   11  17 2
            16   12  18 1
            17   14  19 2
            18   16  20 2
            19   17  21 1
            20   18  22 1
            21   20  23 1
            22   22  24 1
            23   22  25 1
            24   24  26 1
            25   25  27 1
            26   26  28 1
            27   13  15 1
            28   15  19 1
            29   21  23 2
            30   27  28 1
            31    8  29 1

» Japanese version   » Back

KEGG   DRUG: BiperidenHelp
Entry
D00779                      Drug                                   

Name
Biperiden (JAN/USP/INN);
Akineton (TN)
Formula
C21H29NO
Exact mass
311.2249
Mol weight
311.4611
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
 DG01745  Anticholinergic antiparkinson agent
 DG01967  Antiparkinson agent
  DG01745  Anticholinergic antiparkinson agent
Remark
Same as: C07941
ATC code: N04AA02
Chemical structure group: DG00852
Product (DG00852): D02246<JP> D02247<JP>
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
Comment
Centrally active anticholinergic drugs
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Drug interaction
Structure map
map07057  Antiparkinsonian agents
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA02 Biperiden
      D00779  Biperiden (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D00779  Biperiden (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 514-65-8
PubChem: 7847844
ChEBI: 3112
ChEMBL: CHEMBL1101
DrugBank: DB00810
LigandBox: D00779
NIKKAJI: J2.059A
LinkDB All DBs
KCF data Show

ATOM        23
            1   C1y C    26.3034   -7.3312
            2   C1d C    26.3034   -8.7346
            3   C1y C    27.5665   -6.6295
            4   C1x C    25.1105   -6.6295
            5   C8y C    27.5665   -9.4363
            6   C1b C    25.1105   -9.4363
            7   C1x C    26.5841   -5.6471
            8   C2x C    27.5665   -5.2260
            9   C1y C    25.1105   -5.2260
            10  C8x C    27.5665  -10.8397
            11  C8x C    28.7594   -8.7346
            12  C1b C    23.9176   -8.7346
            13  C2x C    26.3736   -4.5243
            14  C8x C    28.6892  -11.5414
            15  C8x C    29.9523   -9.5065
            16  N1y N    22.6545   -9.4363
            17  C8x C    29.9523  -10.8397
            18  C1x C    22.6545  -10.8397
            19  C1x C    21.4616   -8.7346
            20  C1x C    21.4616  -11.4713
            21  C1x C    20.2687   -9.4363
            22  C1x C    20.2687  -10.7696
            23  O1a O    27.5188   -8.0329
BOND        26
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    5  11 2
            11    6  12 1
            12    8  13 2
            13   10  14 2
            14   11  15 1
            15   12  16 1
            16   14  17 1
            17   16  18 1
            18   16  19 1
            19   18  20 1
            20   19  21 1
            21   20  22 1
            22    7   9 1
            23    9  13 1
            24   15  17 2
            25   21  22 1
            26    2  23 1

» Japanese version   » Back

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