KEGG   DRUG: Methoxypromazine maleateHelp
Entry
D02605                      Drug                                   

Name
Methoxypromazine maleate
Formula
C18H22N2OS. C4H4O4
Exact mass
430.1562
Mol weight
430.5172
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction
Interaction
Drug interaction
Structure map
map07029  Antipsychotics - phenothiazines
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D02605  Methoxypromazine maleate
BRITE hierarchy
Other DBs
CAS: 3403-42-7
PubChem: 17396775
ChEMBL: CHEMBL2104822
LigandBox: D02605
NIKKAJI: J220.159C
LinkDB All DBs
KCF data Show

ATOM        30
            1   C8x C    22.5471  -19.2822
            2   C8x C    22.5471  -20.6738
            3   C8x C    23.7522  -21.3696
            4   C8y C    24.9574  -20.6738
            5   C8y C    24.9574  -19.2822
            6   C8x C    23.7522  -18.5864
            7   S2x S    26.1626  -21.3696
            8   C8y C    27.3677  -20.6738
            9   C8y C    27.3677  -19.2822
            10  N1y N    26.1626  -18.5864
            11  C8x C    28.5730  -21.3696
            12  C8x C    29.7781  -20.6738
            13  C8y C    29.7781  -19.2822
            14  C8x C    28.5730  -18.5864
            15  C1b C    26.1626  -17.1948
            16  C1b C    27.3698  -16.4978
            17  C1a C    29.7393  -15.1019
            18  O2a O    30.9873  -18.5841
            19  C1a C    32.1776  -19.2715
            20  C1b C    28.5920  -17.2032
            21  N1c N    29.7731  -16.5211
            22  C1a C    30.9677  -17.2108
            23  C2b C    37.7852  -17.3339
            24  C2b C    39.5247  -17.3339
            25  C6a C    37.0894  -18.5391
            26  C6a C    40.2205  -18.5391
            27  O6a O    41.6121  -18.5391
            28  O6a O    35.6978  -18.5391
            29  O6a O    37.7757  -19.7274
            30  O6a O    39.5343  -19.7274
BOND        31
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    9  14 1
            17   10  15 1
            18   15  16 1
            19   13  18 1
            20   18  19 1
            21   16  20 1
            22   20  21 1
            23   21  22 1
            24   21  17 1
            25   23  24 2
            26   23  25 1
            27   24  26 1
            28   26  27 2
            29   25  28 1
            30   25  29 2
            31   26  30 1

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