| Entry |
|
|---|
| Name |
Bimatoprost (JAN/USAN/INN);
Lumigan (TN);
Latisse (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C25H37NO4
|
|---|
| Exact mass |
415.2723
|
|---|
| Mol weight |
415.5656
|
|---|
| Structure |
|
|---|
| Class |
Other
DG02573 Prostanoid derivative
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiglaucoma, Eyelash growth stimulant |
|---|
| Disease |
Open angle glaucoma [DS: H00612] |
|---|
| Comment |
Prostamide analog
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EE Prostaglandin analogues
S01EE03 Bimatoprost
D02724 Bimatoprost (JAN/USAN/INN) <JP/US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatological Agents, Other
Miscellaneous, dermatological
Bimatoprost
D02724 Bimatoprost (JAN/USAN/INN)
Ophthalmic Agents
Intraocular Pressure Lowering Agents
Ophthalmic Prostaglandin and Prostamide Analogs
Bimatoprost
D02724 Bimatoprost (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D02724 Bimatoprost (JAN/USAN/INN)
2 Agents affecting individual organs
26 Epidermides
267 Hair remedies
2679 Others
D02724 Bimatoprost (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostaglandin
PTGFR
D02724 Bimatoprost (JAN/USAN/INN) <JP/US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D02724
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D02724
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D02724
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D02724
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 30
1 C1y C 11.4800 -17.9900
2 C1y C 11.4800 -16.5900
3 C1y C 10.1485 -16.1574
4 C1x C 9.3256 -17.2900
5 C1y C 10.1485 -18.4226
6 O1a O 9.7197 -14.8378
7 O1a O 9.7197 -19.7422
8 C1b C 12.6924 -15.8900
9 C2b C 13.9049 -16.5900
10 C2b C 12.6924 -18.6900
11 C2b C 13.9049 -17.9900
12 C1c C 15.1173 -18.6900
13 C1b C 16.3297 -17.9900
14 C1b C 17.5422 -18.6900
15 C2b C 15.3049 -16.5900
16 C1b C 16.5424 -15.8900
17 C1b C 17.7549 -16.5900
18 C1b C 18.9673 -15.8900
19 C5a C 20.1797 -16.5900
20 N1b N 21.3922 -15.8900
21 C1b C 22.6046 -16.5900
22 O1a O 15.1173 -20.0900
23 C8y C 17.5422 -20.0900
24 C8x C 16.3508 -20.7781
25 C8x C 16.3510 -22.1781
26 C8x C 17.5636 -22.8779
27 C8x C 18.7550 -22.1898
28 C8x C 18.7547 -20.7898
29 O5a O 20.1797 -17.9899
30 C1a C 23.8211 -15.8877
BOND 31
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 3 6 1 #Down
7 5 7 1 #Down
8 2 8 1 #Down
9 8 9 1
10 1 10 1 #Up
11 10 11 2
12 11 12 1
13 12 13 1
14 13 14 1
15 9 15 2
16 15 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 12 22 1 #Down
23 14 23 1
24 23 24 2
25 24 25 1
26 25 26 2
27 26 27 1
28 27 28 2
29 23 28 1
30 19 29 2
31 21 30 1
|
|---|
